Sutthira Sutthasupa

• Ph.D (Polymer Chemistry)
• Professor (Associate) at Chiang Mai University

Amino acid derived norbornene monomers having carboxy (1) and amino groups (2) were synthesized and subjected to ring-opening metathesis copolymerization with various feed ratios using the Grubbs second generation ruthenium catalyst. The M(n)'s of the copolymers ranged from 5300 to 9400 (M(w)/M(n) = 1.40-1.69). The monomer conversion and M(n) of th...

Amino acid derived norbornene monomers having unprotected carboxy (1) and amino groups (2) and 7-oxanorbornene having ester groups (3) were block copolymerized using the Grubbs ruthenium complexes. In the combination of 1 and 2, block copolymers with number-average molecular weights ranging from 43 000 to 95 000 were obtained in good yields. Poly(1...

This article reviews the development of catalysts for ring-opening metathesis polymerization (ROMP), synthesis of polymers bearing amino acids and peptides by ROMP of functionalized norbornenes, formation of aggregates and micelles, and applications of the polymers to medical materials. It also describes the control of monomer unit sequences, that...

Norbornene macromonomers 2 and 3 bearing 10- and 20-mers of lactide were synthesized by ring-opening polymerization of lactide using 5-norbornene-2, 3-exo-exo-dimethanol as an initiator and DBU as a catalyst. Macromonomers 2 and 3 were copolymerized with amino acid derived norbornene monomer 1, using the Grubbs 2nd generation ruthenium catalyst. Th...

Aspartic acid derived norbornene monomer 1 and indomethacin-conjugated norbornene monomer 2 were block copolymerized via ring-opening metathesis polymerization (ROMP) using the Grubbs 2nd generation ruthenium complexes. The block copolymers with number-average molecular weights ranging from 11 700 to 15 300 were obtained in good yields. Well-contro...

A hydrogel-based colorimetric oxygen indicator that exhibits high photoreduction efficiency and fast oxygen response was produced by integrating ZnO nanoparticles and a redox dye into an alginate hydrogel matrix. We found that varying the ZnO and glycerol [external sacrificial electron donor (SED)] content significantly affected the swelling behavi...

The alginate beads encapsulated thyme (AT), rosemary (AR) and geranium (AG) essential oils (EOs) were prepared to inhibit lipid oxidation in lard and coconut oil. The result showed that beads dried in hot air oven (45 °C) encapsulated higher amount of EOs than drying by desiccation method. Sachets containing AT, AR and AG were applied in PET bottle...

Hydrogels based on alginate and methylcellulose were developed as a colorimetric indicator for monitoring minced pork spoilage. The hydrogel was fabricated by an external gelation method using Ca²⁺ as the crosslinking agent. The pH-sensitive dye bromothymol blue was incorporated into the hydrogel to act as an indicator. The hydrogel’s swelling inde...

Encapsulation of clove, lavender essential oils (EOs)m and vanillin into chitosan (CH) and alginate (AL) beads was prepared using a simple oil‐entrapped emulsion to inhibit Botrytis cinerea in table grapes. The overall encapsulation efficiency of AL beads was observed to be higher than that of CH beads. The release of EO from beads depended mostly...

Thermo-responsive micelles were prepared from brush-like block copolymers of proline-derived norbornene and macromonomers bearing oligo(lactide) groups. The brush-like polymers with moderate molecular weights were synthesized by the ring-opening metathesis block copolymerization of a proline-functionalized norbornene (1) with norbornene macromonome...

Leucine-derived norbornene monomer (1), oligo(lactic acid)-derived norborne macromonomer (2) and indomethacin-conjugated norbornene (3) were synthesized and polymerized using the Grubbs ruthenium complex as a catalyst. Macromonomer 2 was synthesized by the ring-opening polymerization of lactide using 5-norbornene-2,3-exo,exo-dimethanol as an initia...

Amino acid-derived novel norbornene monomers (1a-2b) having nonprotected amino groups, together with tert-butoxycarbonyl (Boc) protected ones (1a-Boc-2b-Boc) were synthesized and polymerized by ring-opening metathesis polymerization using the Grubbs second generation ruthenium catalyst. The l-alanine-derived endo,endo-monomer 1a with amino groups g...

Amino acid‐derived novel norbornene monomers were synthesized and polymerized with ruthenium catalysts. The polymerization rates were affected by the stereo structure of the monomers; exo,exo ‐NBL underwent ROMP faster to give the polymers in higher yields than the endo,exo ‐counterpart. The Grubbs 2nd generation catalyst was the most effective for...

Amino acid derived novel norbornene monomers, N,N'-(exo-bicyclo[2.2.1]hept-5-en-2,3-diyldi-carbonyl) biS-L-leucine methyl ester (1) and N,N'-(exo-bicyclo[2.2.1]hept-5-en-2,3-diyldicarbonyl) biS-L-leucine (2) were synthesized and polymerized with Grubbs second generation ruthenium catalyst. The homopolymers, random, and block copolymers with number-...

Amino acid-derived novel norbornene diester derivatives, 5-norbornene-endo,endo-2,3-dicarboxylic acid bis((S)-2-N-(tert-butoxycarbonyl)aminopropyl) ester (1a), 5-norbornene-exo,exo-2,3-dicarboxylic acid bis((S)-2-N-(tert-butoxycarbonyl)aminopropyl) ester (1b), bis(N-α-(tert-butoxycarbonyl)-l-alanine) 5-norbornene-2,3-endo,endo-dimethyl ester (2a),...

Amino acid-derived novel norbornene derivatives, N,N′-(endo-bicyclo[2.2.1] hept-5-en-2,3-diyldicarbonyl) bis-L-alanine methyl ester (NBA), N,N′-(endo-bicyclo[2.2.1]hept-5-en-2,3-diyldicarbonyl) bis-L-leucine methyl ester (NBL), N,N′-(endo-bicyclo[2.2.1]hept-5-en-2,3-diyldicarbonyl) bis-L-phenylalanine methyl ester (NBF) were synthesized and polymer...

Kyoto University (京都大学) 0048 新制・課程博士 博士(工学) 甲第15038号 工博第3187号 新制/工/1479 27499 2010-01-25 京都大学大学院工学研究科高分子化学専攻 (主査)教授 赤木 和夫, 教授 長谷川 博一, 准教授 三田 文雄 学位規則第4条第1項該当