Sushrut Arora

Vax-Immune™ Diagnostics LLC

Antibody-based therapies have garnered considerable success in recent years. This is due to the availability of strategies to successfully engineer antibodies into humanized forms, better understanding of the biological processes involved in cancer development, the availability of novel recombinant antibody formats, better antibody selection platfo...

Antibodies continue to be extremely utilized entities in myriad applications including basic research, imaging, targeted delivery, chromatography, diagnostics, and therapeutics. At production stage, antibodies are generally present in complex matrices and most of their intended applications necessitate purification. Antibody purification has always...

Bovine mastitis, an inflammation of the mammary gland in cows, is a major challenge for the dairy industry worldwide as it lowers milk yield, reduces milk quality and increases overall production costs. Early diagnosis is of the utmost importance. N-acetyl-β-D-glucosaminidase (NAGase) is an enzyme released into milk during inflammation and acts as...

Bovine mastitis, the most significant disease of dairy herds, has huge effects on farm economics due to reduction in milk production and treatment costs. Traditionally, methods of detection have included estimation of somatic cell counts, an indication of inflammation, measurement of biomarkers associated with the onset of the disease (e.g. the enz...

The present study was conducted to assess the best method of the most commonly used methods for detection of aeromonads in foods of animal origin. With this objective an OMP based indirect plate ELISA and a duplex-PCR using primers targeting aerolysin gene and 16S rRNA gene and yielding amplicons of 252 bp and 599 bp, respectively, were standardize...

There are significant challenges in food analysis, problems with food contamination and authentication, and a worldwide need to ensure food safety. This book provides a description of antibody-based technologies used in food analysis. It focuses on key applications, outlining the approaches used, their advantages and limitations, and describes futu...

Background: Ureaplasma spp are a known risk factor for bronchopulmonary dysplasia (BPD) in premature infants. Emerging research suggests treatment with azithromycin or clarithromycin in the first days of life reduces BPD in Ureaplasma spp positive infants. Side effects of these antibiotics make it imperative to optimize reliable non-invasive scree...

Abstract Antibodies are extensively utilized entities in biomedical research, and in the development of diagnostics and therapeutics. Many of these applications require high amounts of antibodies. However, meeting this ever-increasing demand of antibodies in the global market is one of the outstanding challenges. The need to maintain a balance betw...

The availability of purified antibodies is prerequisite for many applications and the appropriate choice(s) of antibody-purification steps is crucial. Numerous methods have been developed for the purification of antibodies; however, affinity chromatography-based methods are the most extensively utilized. These methods are based on highly specific a...

Hepatitis E is a virus mediated liver disease caused by hepatitis E virus (HEV). There are an estimated 3 million cases of acute HEV infection every year, causing 70,000 hepatitis E-related deaths worldwide. HEV is transmitted via the fecal-oral route. Contaminated water and food are main source of infection. HEV is classified in the family Hepevir...

Improved, cost–effective and rapid diagnostic are highly desirable for detection of veterinary pathogens. They are further desirable for veterinary viral pathogen detection as these pathogens generally cause major ailments in animals. Additionally, there are numerous emerging and re– emerging viral pathogens with many of them being zoonotic, and ha...

The global antibody market has grown exponentially due to increasing applications in research, diagnostics and therapy. Antibodies are present in complex matrices (e.g. serum, milk, egg yolk, fermentation broth or plant-derived extracts). This has led to the need for development of novel platforms for purification of large quantities of antibody wi...

The primary focus of this review is the discussion of how biosensor-based platforms can be used in conjunction with microbial cells for monitoring, environmental and industrial applications. Two approaches will be comprehensively discussed. The first of these will examine how immunosensors can be used for the sensitive and selective detection of ba...

The present study was carried out to record the antibiotic sensitivity pattern of the S. aureus strains isolated from cases of subclinical bovine mastitis.

The excessive and injudicious use of antimicrobials, prophylactic or therapeutic, in treatment of dairy animals, especially for treating mastitis, causes the excretion of the residues of these drugs in milk. Certain antimicrobial residues persist in milk for prolonged periods and cause allergic disturbances and specific toxicities to consumers. Var...

Curvularia spp. commonly occur as contaminants fungi but the significance of this agent as a pathogen especially in immunocompromised hosts is increasing. This study reports a rare case of isolation of fungus Curvulaira spp. from milk sample of a subclinical case of mastitis in goat.

A total of 94 raw cow milk samples from unorganized dairies in Mathura, Uttar Pradesh, India, were subjected to a disc assay using Bacillus subtilis as the test organism in order to determine antimicrobial residues [date not given]. 23 (24.47%) samples were positive for antimicrobial residues, characterized by a distinct zone of inhibition, while 1...

Ninety dairy products (10 samples each of butter, khoa and kulfi obtained in the summer, winter and rainy seasons) from retail outlets and vendors in Mhow and Indore, India, were analysed for the presence of yeasts and moulds. It was shown that overall yeast and mould counts were highest in the rainy season, followed by winter and summer seasons. Y...