Susanne Zeilinger

Susanne Zeilinger
University of Innsbruck | UIBK · Department of Microbiology

PhD, Professor of Microbiology

About

129
Publications
48,981
Reads
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7,214
Citations
Citations since 2016
37 Research Items
4178 Citations
20162017201820192020202120220200400600800
20162017201820192020202120220200400600800
20162017201820192020202120220200400600800
20162017201820192020202120220200400600800
Introduction
Susanne Zeilinger currently works at the Institute of Microbiology, University of Innsbruck. Susanne does research in Mycology, Microbiology and Genetics. Their current research is on microbial interactions with a focus on the mycoparasitic fungus-fungus interaction. Research questions deal with signal exchange between the interaction partners, recognition events and cellular responses.
Additional affiliations
October 2015 - present
University of Innsbruck
Position
  • Professor
October 2001 - April 2019
Technische Universität Wien
Position
  • Project Manager
April 1996 - August 1996
Università degli Studi di Napoli Federico II
Position
  • Guest Researcher

Publications

Publications (129)
Article
Full-text available
Background Reverse transcription quantitative real-time PCR (RT-qPCR) is a well-established method for analysing gene expression. Most RT-qPCR experiments in the field of microbiology aim for the detection of transcriptional changes by relative quantification, which means the comparison of the expression level of a specific gene between different s...
Article
Full-text available
Trichoderma spp. are widely used as plant disease biocontrol agents in agriculture. Mycoparasitism, which is an ancestral trait of Trichoderma, is one of the most important mechanisms of reducing the pathogen inocula. Mycoparasitism is a complex physiological process that should be viewed in the broad perspective of microbial competition, and invol...
Article
Full-text available
Trichoderma atroviride (Ascomycota, Sordariomycetes) is a well-known mycoparasite applied for protecting plants against fungal pathogens. Its mycoparasitic activity involves processes shared with plant and human pathogenic fungi such as the production of cell wall degrading enzymes and secondary metabolites and is tightly regulated by environmental...
Article
Full-text available
Trichoderma atroviride is a mycoparasitic fungus used as biological control agent against fungal plant pathogens. The recognition and appropriate morphogenetic responses to prey-derived signals are essential for successful mycoparasitism. We established microcolony confrontation assays using T. atroviride strains expressing cell division cycle 42 (...
Article
Full-text available
The dry rot fungus Serpula lacrymans causes significant structural damage by decaying construction timber, resulting in costly restoration procedures. Dry rot fungi decompose cellulose and hemicellulose and are often accompanied by a succession of bacteria and other fungi. Bacterial-fungal interactions (BFI) have a considerable impact on all the pa...
Article
Full-text available
Fusarium oxysporum is a plant pathogenic fungus leading to severe crop losses in agriculture every year. A sustainable way of combating this pathogen is the application of mycoparasites—fungi parasitizing other fungi. The filamentous fungus Trichoderma atroviride is such a mycoparasite that is able to antagonize phytopathogenic fungi. It is therefo...
Article
Full-text available
The fungal cell wall is composed of a cross-linked matrix of chitin, glucans, mannans, galactomannans, and cell wall proteins with mannan chains. Cell wall mannans are directly attached to the cell wall core, while the majority of mannoproteins is produced with a glycosylphosphatidylinositol (GPI) anchor and then transferred to β-1,6-glucan in the...
Chapter
Secondary metabolites (SMs) are low molecular-weight compounds derived from primary metabolites via specialized pathways and are produced mainly by microorganisms and plants. Fungi produce a huge number and variety of SMs, many of which have interesting biological activities. SMs can provide self-protection and may act as mediators for communicatio...
Article
Full-text available
Trichoderma atroviride is a mycoparasitic fungus used as biological control agent to protect plants against fungal pathogens. Successful biocontrol is based on the perception of signals derived from both the plant symbiont and the fungal prey. Here, we applied three different chemotropic assays to study the chemosensing capacity of T. atroviride to...
Preprint
Full-text available
The dry-rot fungus Serpula lacrymans causes enormous structural damage by decaying construction timber thereby resulting in tremendous financial loss. Dry-rot fungi decompose cellulose and hemicellulose and, if the wood remains wet, are often accompanied by a succession of bacteria and other fungi. Bacterial-fungal interactions have considerable im...
Article
Transformation enables the transfer of DNA into fungal cells for subsequent integration into the genome. Due to its versatility in industrial application, transformation is of utmost importance in Trichoderma reesei and hence continuously optimized. As one of the most crucial obstacles in fungal transformation efforts, removal of the cell wall is r...
Article
Full-text available
The ascomycete Trichoderma atroviride is well known for its mycoparasitic lifestyle. Similar to other organisms, light is an important cue for T. atroviride. However, besides triggering of conidiation, little is known on the physiological responses of T. atroviride to light. In this study, we analyzed how cultivation under different light wavelengt...
Preprint
Full-text available
The ascomycete Trichoderma atroviride is well known for its mycoparasitic lifestyle. Similar to other organisms, light is an important cue for T. atroviride. However, besides triggering of conidiation, little is known on the physiological responses of T. atroviride to light. In this study, we analyzed how cultivation under different light wavelengt...
Book
Full-text available
New and Future Developments in Microbial Biotechnology and Bioengineering: Recent Developments in Trichoderma Research covers topics on-Trichoderma biodiversity, strain improvement and related researches in bioprocess technology, chemical engineering, bioremediation process, secondary metabolite production, Protein production, plant disease resista...
Article
Full-text available
The necrotrophic mycoparasite Trichoderma atroviride is a biological pest control agent frequently applied in agriculture for the protection of plants against fungal phytopathogens. One of the main secondary metabolites produced by this fungus is 6-pentyl-α-pyrone (6-PP). 6-PP is an organic compound with antifungal and plant growth-promoting activi...
Article
Full-text available
Single-molecule localization microscopy has boosted our understanding of biological samples by offering access to subdiffraction resolution using fluorescence microscopy methods. While in standard mammalian cells this approach has found wide-spread use, its application to filamentous fungi has been scarce. This is mainly due to experimental challen...
Chapter
Genetic transformation methods are a prerequisite for the functional analysis and modification of genes. About 30 years ago, first reports on the genetic transformation of filamentous fungi have been published, a breakthrough technology not only for scientific purposes but also for fungal biotechnology. Key transformation tools and approaches now r...
Article
Full-text available
Trichoderma atroviride is a strong necrotrophic mycoparasite antagonizing and feeding on a broad range of fungal phytopathogens. It further beneficially acts on plants by enhancing growth in root and shoot and inducing systemic resistance. Volatile organic compounds (VOCs) are playing a major role in all those processes. Light is an important modul...
Chapter
Certain Trichoderma species such as Trichoderma atroviride and Trichoderma virens are successful mycoparasites applied for the protection of plants against fungal pathogens. The direct antagonism of phytopathogenic fungi by Trichoderma mycoparasites comprises several stages and includes the host-triggered activation of “molecular weapons” such as c...
Article
Full-text available
Single molecule localization microscopy is currently revolutionizing the life sciences as it offers, for the first time, insights into the organization of biological samples below the classical diffraction limit of light microscopy. While there have been numerous examples of new biological findings reported in the last decade, the technique could n...
Article
Full-text available
Mycoparasites, e.g. fungi feeding on other fungi, are prominent within the genus Trichoderma and represent a promising alternative to chemical fungicides for plant disease control. We previously showed that the seven-transmembrane receptor Gpr1 regulates mycelial growth and asexual development and governs mycoparasitism-related processes in Trichod...
Article
Full-text available
Aquaporins (AQPs) and aquaglyceroporins (AQGPs) are integral membrane proteins that mediate transport of water and a variety of low molecular weight solutes across biomembranes. We previously identified a gene encoding an AQGPs in Trichoderma harzianum that is up-regulated during biocontrol against Fusarium sp. and has biotechnological applications...
Article
Full-text available
Mycoparasitism is a lifestyle where one fungus establishes parasitic interactions with other fungi. Species of the genus Trichoderma together with Clonostachys rosea are among the most studied fungal mycoparasites. They have wide host ranges comprising several plant pathogens and are used for biological control of plant diseases. Trichoderma as wel...
Article
Necrotrophic Mycoparasites and Their Genomes, Page 1 of 2 Abstract Mycoparasitism is a lifestyle where one fungus establishes parasitic interactions with other fungi. Species of the genus Trichoderma together with Clonostachys rosea are among the most studied fungal mycoparasites. They have wide host ranges comprising several plant pathogens and...
Book
The continuous innovation of molecular and information technologies and the expansion of research into omics dramatically transform the landscape of microbial technology. This book aims to provide a consolidated overview of the research developments within this complex and multidisciplinary topic; encompassing the latest advances and future prospec...
Data
Supporting Information on Chemicals and MALDI MSI Sample Preparation Supplemental Figure S1 Supplemental Figure 2 Supplemental Figure 3 Supplemental Figure 4 Supplemental Figure S5 and S6 Supplemental Figure 7
Article
Full-text available
Gene cluster Peptaibiotics Secondary metabolites Trichoderma VOCs a b s t r a c t Species of the genus Trichoderma inhabit diverse environments and undergo a variety of interactions with different other organisms. Mycoparasitic Trichoderma species are successfully applied as bio-fungicides due to their plant-protecting abilities and they are prolif...
Article
Full-text available
Studying microbial interactions by MALDI mass spectrometry imaging (MSI) directly from growing media is a difficult task if high sensitivity is demanded. We present a quick and robust sample preparation strategy for growing fungi (Trichoderma atroviride, Rhizoctonia solani) on glass slides to establish a miniaturized confrontation assay. By this we...
Article
Full-text available
The genus Trichoderma contains fungi with high relevance for humans, with applications in enzyme production for plant cell wall degradation and use in biocontrol. Here, we provide a broad, comprehensive overview of the genomic content of these species for “hot topic” research aspects, including CAZymes, transport, transcription factors, and develop...
Article
Full-text available
Fungi interact with plants in various ways, with each interaction giving rise to different alterations in both partners. While fungal pathogens have detrimental effects on plant physiology, mutualistic fungi augment host defence responses to pathogens and/or improve plant nutrient uptake. Tropic growth towards plant roots or stomata, mediated by ch...
Article
The Trichoderma atroviride 7-transmembrane receptor Gpr1 is essential for fungal mycoparasitism and interacts with a Sur7 family membrane protein S. Zeilinger,1,2 S. Gruber,2 T. Radebner2 and A. Lichius2 1Universit€at Innsbruck, Institut f€ur Mikrobiologie, Innsbruck, Austria and 2Technische Universit€at Wien, Institute of Chemical Engineering, Wie...
Chapter
Secondary metabolites produced by fungi have a tremendous impact on the human society; some are exploited for their antibiotic and pharmaceutical activities, others are involved in disease interactions with other organisms such as plants or animals. The Springer book series on fungal biology includes two volumes on the Biosynthesis and Molecular Ge...
Article
In this work, we present the 'Peptaibiotics Database' (PDB), a comprehensive online resource, which intends to cover all Aib-containing non-ribosomal fungal peptides currently described in scientific literature. This database shall extend and update the recently published 'Comprehensive Peptaibiotics Database' and currently consists of 1,297 peptai...
Chapter
Peptaibiotics and related peptaibols are linear or cyclic peptide antibiotics characterized by the presence of the non-proteinogenic amino acid alpha-aminoisobutyric acid. They belong to the constantly expanding group of fungal secondary metabolites with more than 1000 different peptaibiotics identified thus far. Peptaibiotics are biosynthesized by...
Book
Full-text available
This book continues the exploration of fungal secondary metabolism and underlying genetics initiated in the first volume, adding analysis of regulatory key players and epigenetic control of their biosynthesis, genomics- and metabolomics-guided approaches. This work unearths the potential of fungi as resources of novel biologically active substances...
Book
Full-text available
This book continues the exploration of fungal secondary metabolism and underlying genetics initiated in the first volume, adding analysis of regulatory key players and epigenetic control of their biosynthesis, genomics- and metabolomics-guided approaches. This work unearths the potential of fungi as resources of novel biologically active substances...
Article
Full-text available
Mycoparasitic species of the fungal genus Trichoderma are potent antagonists able to combat plant pathogenic fungi by direct parasitism. An essential step in this mycoparasitic fungus-fungus interaction is the detection of the fungal host followed by activation of molecular weapons in the mycoparasite by host-derived signals. The Trichoderma atrovi...
Book
Full-text available
This volume describes the more relevant secondary metabolites of different fungi with current information on their biosynthesis and molecular genetics. Bolstered with color illustrations and photographs, the book describes the possible application of molecular genetics to directed strain improvement in great detail. The needs for future development...
Article
Full-text available
Fungus-Fungus Interactions 1.5 million fungal species are estimated to exist on our planet which are assumed to account for at least 25% of the global biomass. Fungi inhabit a broad range of environmental niches and, due to their nutritional versatility, perform many essential processes like nutrient recycling and decomposition in global ecosystem...
Chapter
Fungi of the genus Trichoderma display an outstanding adaptability to various ecological conditions and the antagonism and parasitism of other fungi is widespread among Trichoderma species. Besides being able to sense the presence of a prey fungus already from a distance, which implies the involvement of respective cell surface receptors that respo...
Book
Full-text available
This volume describes the more relevant secondary metabolites of different fungi with current information on their biosynthesis and molecular genetics. Bolstered with color illustrations and photographs, the book describes the possible application of molecular genetics to directed strain improvement in great detail. The needs for future development...
Article
A putative terpene cyclase vir4, which is a member of a secondary metabolite cluster, has been deleted in Trichoderma virens to determine its function. The deletion mutants were compared for volatile production with the wild-type as well as two other Trichoderma spp. This gene cluster was originally predicted to function in the synthesis of viridin...
Article
Full-text available
Background Eukaryotic organisms employ cell surface receptors such as the seven-transmembrane G protein-coupled receptors (GPCRs) as sensors to connect to the environment. GPCRs react to a variety of extracellular cues and are considered to play central roles in the signal transduction in fungi. Several species of the filamentous ascomycete Trichod...
Article
Peptaibiotics are nonribosomally biosynthesized peptides, which - according to definition - contain the marker amino acid α-aminoisobutyric acid (Aib) and possess antibiotic properties. Being known since 1958, a constantly increasing number of peptaibiotics have been described and investigated with a particular emphasis on hypocrealean fungi. Start...
Article
Full-text available
The putative methyltransferase LaeA is a global regulator that affects the expression of multiple secondary metabolite gene clusters in several fungi, and it can modify heterochromatin structure in Aspergillus nidulans. We have recently shown that the LaeA ortholog of Trichoderma reesei (LAE1), a fungus that is an industrial producer of cellulase a...
Chapter
Full-text available
This book provides an update on the advances in Trichoderma research, covering most of the aspects related to the biology, genetics, genomics and applications of Trichoderma species. An overview of the importance of Trichoderma spp. in agriculture, industry and medicine (chapter 1) is presented. The remaining articles are broadly classified under t...
Chapter
A method based on solid phase microextraction coupled to gas chromatography–mass spectrometry (GC–MS) for the detection and identification of microbial volatile organic compounds (MVOCs) in the headspace of filamentous fungi is presented. MVOCs are identified by comparison of mass spectra and linear temperature programmed retention indices (LTPRIs)...
Article
Trichoderma spp. are widely used in agriculture as biofungicides. Induction of plant defense and mycoparasitism (killing of one fungus by another) are considered to be the most important mechanisms of Trichoderma-mediated biological control. Understanding these mechanisms at the molecular level would help in developing strains with superior biocont...
Article
Full-text available
Background Species of the fungal genus Trichoderma are important industrial producers of cellulases and hemicellulases, but also widely used as biocontrol agents (BCAs) in agriculture. In the latter function Trichoderma species stimulate plant growth, induce plant defense and directly antagonize plant pathogenic fungi through their mycoparasitic ca...
Data
Full-text available
Phenotype of nptII / tga3Q207L co-transformants on PDA and PDA + 80μg/ml geneticin. The figure shows the colony morphology of co-transformants 3/3 and 4/5 (with ectopic integration of the tga3Q207L gene) and co-transformant 2/1 (with homologous integration of the tga3Q207L gene) grown on PDA and PDA + 80μg/ml geneticin for 4 days at 28°C in the dar...
Article
Full-text available
Mycoparasitic Trichoderma species are applied as biocontrol agents in agriculture to guard plants against fungal diseases. During mycoparasitism, Trichoderma directly interacts with phytopathogenic fungi, preceded by a specific recognition of the host and resulting in its disarming and killing. In various fungal pathogens, including mycoparasites,...
Article
Full-text available
Trichoderma is a genus of common filamentous fungi that display a remarkable range of lifestyles and interactions with other fungi, animals and plants. Because of their ability to antagonize plant-pathogenic fungi and to stimulate plant growth and defence responses, some Trichoderma strains are used for biological control of plant diseases. In this...
Article
Full-text available
Trichoderma is a genus of common filamentous fungi that display a remarkable range of lifestyles and interactions with other fungi, animals and plants. Because of their ability to antagonize plant-pathogenic fungi and to stimulate plant growth and defence responses, some Trichoderma strains are used for biological control of plant diseases. In thi...
Data
Figures that illustrate selected aspects of the main text. Figure S1 provides a phylogeny of Trichoderma NPRSs. Figure S2 compares the numbers of epoxide hydrolase genes in Trichoderma with that in other fungi. Figure S3 compares the codon usage in genes from syntenic and nonsyntenic regions of the genomes of Trichoderma reesei, T. atroviride and T...