Susan Gathercole

Medical Research Council (UKRI) | mrc · MRC Cognition and Brain Sciences Unit

Most cognitive training programs are adaptive, despite limited direct evidence that this maximizes children's outcomes. This randomized controlled trial evaluated working memory training with difficulty of activities presented using adaptive, self‐select, or stepwise compared with an active control. At baseline, immediately, and 6‐months post‐inter...

Despite the abundance of research evaluating working memory training outcomes in children, few studies have examined the underlying cognitive mechanisms. This study aimed to contribute understanding by exploring whether working memory capacity (maximum span) and/or efficiency (basic and cognitive processing speeds), two proposed cognitive mechanism...

Objective A common assumption to maximise cognitive training outcomes is that training tasks should be adaptive, with difficulty adjusted to the individual’s performance. This has only been tested once in adults (von Bastian & Eschen, 2016). We aimed to examine children’s outcomes of working memory training using adaptive, self-select and stepwise...

Gathercole et al. (Journal of Memory and Language, 105, 19-42, 2019) presented a cognitive routine framework for explaining the underlying mechanisms of working memory (WM) training and transfer. This framework conceptualizes training-induced changes as the acquisition of novel cognitive routines similar to learning a new skill. We further infer th...

Background A common yet untested assumption of cognitive training in children is that activities should be adaptive, with difficulty adjusted to the individual’s performance in order to maximize improvements on untrained tasks (known as transfer). Working memory training provides the ideal testbed to systematically examine this assumption as it is...

BACKGROUND A common yet untested assumption of cognitive training in children is that activities should be adaptive, with difficulty adjusted to the individual’s performance in order to maximize improvements on untrained tasks (known as transfer). Working memory training provides the ideal testbed to systematically examine this assumption as it is...

Practitioners frequently use diagnostic criteria to identify children with neurodevelopmental disorders and to guide intervention decisions. These criteria also provide the organising framework for much of the research focussing on these disorders. Study design, recruitment, analysis and theory are largely built on the assumption that diagnostic cr...

The formation of large-scale brain networks, and their continual refinement, represent crucial developmental processes that can drive individual differences in cognition and which are associated with multiple neurodevelopmental conditions. But how does this organization arise, and what mechanisms drive diversity in organization? We use generative n...

A data-driven, transdiagnostic approach was used to identify the cognitive dimensions linked with learning in a mixed group of 805 children aged 5 to 18 years recognised as having problems in attention, learning and memory by a health or education practitioner. Assessments included phonological processing, information processing speed, short-term a...

Transcranial direct current stimulation (tDCS) has been shown to enhance the efficacy and generalisation of working memory (WM) training, but there has been little systematic investigation into how coupling task-specific WM training with stimulation impacts more specifically on transfer to untrained tasks. This randomised controlled trial investiga...

Running span can be performed by either passively listening to memory items or actively updating the target set. Previous research suggests that the active updating process is demanding and time consuming and is favored at slow rates of presentation while the passive strategy is employed at fast rates. Two experiments examined the time course of re...

This study in children born extremely preterm (EP; <28 weeks’ gestational age) or extremely low birth weight (ELBW; <1,000 g) investigated whether adaptive working memory training using Cogmed® is associated with structural and/or functional brain changes compared with a placebo program. Ninety‐one EP/ELBW children were recruited at a mean (standar...

A randomized controlled trial compared complex span and n-back training regimes to investigate the generality of training benefits across materials and paradigms. The memory items and training intensities were equated across programs, providing the first like-with-like comparison of transfer in these two widely used training paradigms. The stimuli...

Is the capacity of short-term memory fixed, or does it improve with practice? It is already known that training on complex working memory tasks is more likely to transfer to untrained tasks with similar properties, but this approach has not been extended to the more basic short-term memory system responsible for verbal serial recall. Here we invest...

Following Conrad (1965, Journal of Verbal Learning and Verbal Behavior, 4, 161–169) it is often assumed that backward verbal serial recall is performed by repeated forward scans through the list and then recalling the last remaining item. Direct evidence for this peel-off strategy is relatively weak, and there has to date been no examination of its...

Running span can be performed by either passively listening to to-be-remembered items or actively updating the target set during presentation. This choice of strategy is influenced by the rate of presentation in the task. Previous research suggests that the active updating process is demanding and time-consuming. It is favored at relatively slow ra...

We present a new framework characterizing training-induced changes in WM as the acquisition of novel cog-nitive routines akin to learning a new skill. Predictions were tested in three studies analyzing the transfer between WM tasks following WM training. Study 1 reports a meta-analysis establishing substantial transfer when trained and untrained ta...

Evidence from dual-task studies suggests that working memory supports the retention and implementation of verbal instructions. One key finding that is not readily accommodated by existing models of working memory is that participants are consistently more accurate at physically performing rather than verbally repeating a sequence of commands. This...

The data presented in this article are produced as part of the original research article entitled “Working memory training involves learning new skills” (Gathercole, Dunning, Holmes & Norris, in press). This article presents a dataset of coded features for pairs of trained and untrained working memory (WM) tasks from randomized controlled trials of...

The cover image, by Joe Bathelt et al., is based on the Paper Children's academic attainment is linked to the global organization of the white matter connectome, DOI: 10.1111/desc.12662.

Objective: To assess the effectiveness of Cogmed Working Memory Training compared with a placebo program in improving academic functioning 24 months post-training in extremely preterm/extremely low birth weight 7-year-olds. Study design: A multicenter double-blind, placebo-controlled randomized controlled trial was conducted across all tertiary...

Running span is generally considered a working memory updating task, yet the mechanisms underlying task execution remain unspecified. We employ a novel paradigm to investigate the time-course of cognitive demand posited to indicate an updating process (Experiment 1) and the impact of varying the rate of stimulus presentation (Experiment 2).

Background A substantial proportion of the school-age population experience cognitive-related learning difficulties. Not all children who struggle at school receive a diagnosis, yet their problems are sufficient to warrant additional support. Understanding the causes of learning difficulties is the key to developing effective prevention and interve...

Literacy and numeracy are important skills that are typically learned during child- hood, a time that coincides with considerable shifts in large-scale brain organization. However, most studies emphasize focal brain contributions to literacy and numeracy development by employing case-control designs and voxel-by-voxel statistical com- parisons. Thi...

Background Academic underachievement often accompanies the symptoms of inattention and hyperactivity/ impulsivity associated with ADHD. The aim of the present study is to establish whether learning difficulties have the same cognitive origins in this comorbid condition as in children who do not have ADHD. Methods Participants were 163 school-aged...

Background: Adaptive working memory training is being implemented without an adequate understanding of developmental trajectories of working memory. We aimed to quantify from Grade 1 to Grade 3 of primary school (1) changes in verbal and visuospatial working memory and (2) whether low verbal and visuospatial working memory in Grade 1 predicts low...

Working memory (WM) skills are closely associated with learning progress in key areas such as reading and mathematics across childhood. As yet, however, little is known about how the brain systems underpinning WM develop over this critical developmental period. The current study investigated whether and how structural brain correlates of components...

Literacy and numeracy are fundamental skills acquired in childhood, a time that coincides with considerable shifts in large-scale brain organisation. However, most studies emphasize focal brain contributions to literacy and numeracy development by employing case-control designs and voxel-by-voxel statistical comparisons. This approach has been valu...

Literacy and numeracy are fundamental skills acquired in childhood, a time that coincides with considerable shifts in large-scale brain organisation. However, most studies emphasize focal brain contributions to literacy and numeracy development by employing case-control designs and voxel-by-voxel statistical comparisons. This approach has been valu...

Symptoms of inattention and hyperactivity frequently co-occur with language difficulties in both clinical and community samples. We explore the specificity and strength of these associations in a heterogeneous sample of 254 children aged 5 to 15 years identified by education and health professionals as having problems with attention, learning and/o...

The extent to which deficits in working memory (WM) are characteristic of children with reading and mathematics difficulties was investigated in a large sample aged 5–15 years reported to have problems in attention, learning and memory. WM performance was highly correlated with reading and mathematics scores. Although deficits in individual tests o...

Two experiments investigated the consequences of action at encoding and recall on the ability to follow sequences of instructions. Children aged 7–9 years recalled sequences of spoken action commands under presentation and recall conditions that either did or did not involve their physical performance. In both experiments, recall was enhanced by ca...

Transcranial random noise stimulation (tRNS), a noninvasive brain stimulation technique, enhances the generalization and sustainability of gains following mathematical training. Here it is combined for the first time with working memory training in a double-blind randomized controlled trial. Adults completed 10 sessions of Cogmed Working Memory Tra...

In the current study, we set out to answer three questions. First, can low scores on working memory tasks reliably detect children with specific maths, specific reading and comorbid maths and reading problems? Second, are the working memory deficits commonly found in children with mathematics and/or reading difficulties core to their learning probl...

Accumulating evidence that working memory supports the ability to follow instructions has so far been restricted to experimental paradigms that have greatly simplified the practical demands of performing actions to instructions in everyday tasks. The aim of the present study was to investigate whether working memory is involved in maintaining infor...

Importance Working memory training may help children with attention and learning difficulties, but robust evidence from population-level randomized controlled clinical trials is lacking.Objective To test whether a computerized adaptive working memory intervention program improves long-term academic outcomes of children 6 to 7 years of age with lo...

This study investigated the involvement of working memory (WM) in following spoken instructions using concurrent tasks designed to disrupt components of the Baddeley and Hitch WM model [Baddeley, A. D., & Hitch, G. J. (1974). Working memory. In G. H. Bower (Ed.), The psychology of learning and motivation: Advances in research and theory (Vol. 8, pp...

The recall of instructions is more accurate if participants are required to physically perform rather than repeat back the information. Here we demonstrate that this effect can be selectively disrupted by a secondary task designed to disrupt the encoding of motoric representations.

This study investigated whether working memory training is effective in enhancing verbal memory in children with low language abilities (LLA). Cogmed Working Memory Training was completed by a community sample of children aged 8–11 years with LLA and a comparison group with matched non-verbal abilities and age-typical language performance. Short-te...

Low working memory (WM) is strongly linked with poor academic outcomes. WM capacity increases across childhood but how exposure to school is associated with WM development is not known. We aimed to determine extent to which chronological age and schooling duration are associated with WM at the population level. In 2012, children in Grade 1 (the sec...

Several studies have revealed that the working memory and its components are involved in the process of learning to read and Baddeley’s model (1986) best grasps this process as a whole. The first aim of this study is to carry out a longitudinal study on typical developed children, in order to assess the temporal evolution of the working memory proc...

The purpose of this study was to compare working memory (WM), executive function, academic ability, and problem classroom behaviors in children aged 8–11 years who were either identified via routine screening as having low WM, or had been diagnosed with ADHD. Standardized assessments of WM, executive function and reading and mathematics were admini...

Working memory skills have been shown to be enhanced by adaptive training in several randomised controlled trials. Here, two field trials were conducted in which teachers administered working memory training to their own pupils in school. Twenty-two children aged 8–9 years participated in Trial 1. In Trial 2, 50 children aged 9–11 years with the lo...

Two studies investigated whether the greater Stroop interference reported in children with reading difficulties compared to typical readers of the same age represents a generalized deficit in interference control or a consequence of their reading problems. In Study 1, a color-word Stroop task and a nonverbal task involving responses to locations as...

This article makes some observations on the Gospel of Thomas in connection with the responses to Goodacre's Thomas and the Gospels and Gathercole's Composition of the Gospel of Thomas. It notes that the order of Thomas's sayings and the genre of Thomas are irrelevant to the question of dependence or independence. More important to the question is t...

Chacko et al.'s investigation of the clinical utility of WM training to alleviate key symptoms of ADHD is timely and substantial, and marks a significant point in cognitive training research. Cogmed Working Memory Training (CWMT) involves intensive practice on multiple memory span tasks that increase in difficulty as performance improves with pract...

The spatiotemporal profile of activation of the prefrontal cortex in verbal and non-verbal recognition memory was examined using magnetoencephalography (MEG). Sixteen neurologically healthy right-handed participants were scanned whilst carrying out a modified version of the Doors and People Test of recognition memory. A pattern of significant prefr...

In recent years, there has been an increase in the number of students with learning difficulties entering post-secondary education. Research had shown that younger students with working memory deficit will typically experience learning difficulties. The present study investigates the working memory performance and self-reported learning strategies...

Very preterm children exhibit difficulties in working memory, a key cognitive ability vital to learning information and the development of academic skills. Previous research suggests that an adaptive working memory training intervention (Cogmed) may improve working memory and other cognitive and behavioural domains, although further randomised cont...

Children with low working memory typically make poor educational progress, and it has been speculated that difficulties in meeting the heavy working memory demands of the classroom may be a contributory factor. Intensive working memory training has been shown to boost performance on untrained memory tasks in a variety of populations. This first ran...

For this research, we used a dual-task approach to investigate the involvement of working memory in following written instructions. In two experiments, participants read instructions to perform a series of actions on objects and then recalled the instructions either by spoken repetition or performance of the action sequence. Participants engaged in...

The current study investigated the cause of the reported problems in working memory in children with reading difficulties. Verbal and visuospatial simple and complex span tasks, and digit span and reaction times tasks performed singly and in combination, were administered to 46 children with single word reading difficulties and 45 typically develop...

The current experiment examined the relative advantage of an errorless learning technique over an errorful one in the acquisition of novel names for unfamiliar objects in typically developing children aged between 7 and 9years. Errorless learning led to significantly better learning than did errorful learning. Processing speed and vocabulary predic...

Highlights ► Working memory training has the potential to improve cognitive functioning ► Not all intervention research can employ full clinical trials methodology ► Evidence for efficacy should be based on a balanced evaluation of all evidence.

This paper reports a latent variable study exploring the specific links between executive processes of working memory, phonological short-term memory, phonological awareness, and proficiency in first (L1), second (L2), and third (L3) languages in 8- to 9-year-olds experiencing multilingual education. Children completed multiple L1-measures of compl...

This study investigates the relationship between working memory and language in young children growing up in a multilingual environment. The aim is to explore whether mechanisms of short-term storage and cognitive control hold similar relations to emerging language skills and to investigate if potential links are mediated by related cognitive abili...

Recent studies have shown that individuals with Down syndrome (DS) are poorer than controls in performing verbal and visuospatial dual tasks. The present study aims at better investigating the dual task deficit in working memory in individuals with DS. Forty-five individuals with DS and 45 typically developing children matched for verbal mental age...

Low academic achievement is common and is associated with adverse outcomes such as grade repetition, behavioural disorders and unemployment. The ability to accurately identify these children and intervene before they experience academic failure would be a major advance over the current 'wait to fail' model. Recent research suggests that a possible...

Findings from a longitudinal study designed to investigate phonological working memory skills in preschool children are reported. Two phonological memory tests, digit span and nonword repetition, were given to a large cohort of children at 3,4 and 5 years of age. The majority of children at all ages cooperated on both tests even at 3 years of age,...

Rhythmic grouping enhances verbal serial recall, yet very little is known about memory for rhythmic patterns. The aim of this study was to compare the cognitive processes supporting memory for rhythmic and verbal sequences using a range of concurrent tasks and irrelevant sounds. In Experiment 1, both concurrent articulation and paced finger tapping...

This study investigated how prosodic aspects and wordlikeness of nonwords affect young Japanese children's repetition of nonwords. We contrasted two conditions in which a nonword comprised of two morae was pronounced with and without a small pause between the two morae. We also manipulated accent patterns of presentation of nonwords. The results in...

An accumulating body of research suggests that adaptive training can effectively boost working memory in both children and adults. The aim of this study was test whether gains in working memory transfer to gains in learning and other cognitive skills. A randomised controlled trial was conducted with 72 children identified as having poor working mem...

Studies have shown that extensive training on artificial WM tasks benefits performance on other rarefied memory tasks administered under controlled conditions in children and adults. The aim of the current study is to establish whether these benefits will transfer to improvements in children’s reading, language and mathematical skills, as well as t...

Poor working memory affects approximately 15% of children. It is characterized by inattentive, distractible behavior that is accompanied by failures to complete everyday activities that require focused or sustained attention. Typically, children with poor working memory have normal social integration, normal levels of emotional control, and self-es...

The present study investigates how working memory and fluid intelligence are related in young children and how these links develop over time. The major aim is to determine which aspect of the working memory system—short-term storage or cognitive control—drives the relationship with fluid intelligence. A sample of 119 children was followed from kind...

Two contrasting forms of classroom-based intervention were implemented with 256 primary school children identified as having working memory (WM) difficulties. In one, teaching staff were trained to provide educational environments that were sensitive to the needs of identified children with WM difficulties. The second form of intervention utilized...

This study evaluated the impact of two interventions—a training program and stimulant medication—on working memory (WM) function in children with attention deficit hyperactivity disorder (ADHD). Twenty-five children aged between 8 and 11 years participated in training that taxed WM skills to the limit for a minimum of 20 days, and completed other a...

A good working memory is crucial to becoming a successful leaner, yet there is very little material available in an easy-to-use format that explains the concept and offers practitioners ways to support children with poor working memory in the classroom. This book provides a coherent overview of the role played by working memory in learning during t...

The aim of the present study was to investigate whether behaviours typical of working memory problems are associated with poor academic attainment in those with attention-deficit-hyperactivity disorder (ADHD), as well as a non-clinical group identified on the basis of working memory difficulties. Children clinically diagnosed with ADHD-combined (n=...

Background: Deficits in executive functions have been widely reported to characterise individuals with ADHD. The aim of this study was to evaluate the utility of a range of executive function measures for identifying children with ADHD. Method: Eighty-three children with ADHD and 50 normally-developing children without ADHD were assessed on measure...

The objective of this study was to assess the effects of atomoxetine on treating attention-deficit/hyperactivity disorder (ADHD), on reading performance, and on neurocognitive function in youth with ADHD and dyslexia (ADHD+D). Patients with ADHD (n = 20) or ADHD+D (n = 36), aged 10-16 years, received open-label atomoxetine for 16 weeks. Data from t...