Susan Curtiss

Susan Curtiss
University of California, Los Angeles | UCLA · Department Of Linguistics

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68
Publications
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Publications

Publications (68)
Article
Full-text available
Purpose A previous study showed that assessment of language laterality could be improved by adding grammar tests to the recovery phase of the intracarotid amobarbital procedure (IAP) (Połczyńska et al. 2014). The aim of this study was to further investigate the extent to which grammar tests lateralize language function during the recovery phase of...
Data
Activation in grammar and standard tests in epilepsy (E) and tumor (T) patients. Lesion images are included for all tumor patients. Images of three epilepsy patients (E3, E4, E13) show a prior resection cavity. Overall, the grammar tests generate more robust activations in language areas than the standard test.
Data
Two-sample t-tests (uncorrected) run for patients with significant ANOVA tests (Table 4) to determine task type skew directionality (greater percent signal change in grammar or standard tests) within each ROI. Region stats with NaN denote regions which have been ablated by tumor masses or edema.
Article
Full-text available
Introduction Brain surgery in the language dominant hemisphere remains challenging due to unintended post-surgical language deficits, despite using pre-surgical functional magnetic resonance (fMRI) and intraoperative cortical stimulation. Moreover, patients are often recommended not to undergo surgery if the accompanying risk to language appears to...
Article
This article has no abstract.
Chapter
This article has no abstract.
Article
This study reports on functional morpheme (I, D, and C) production in the spontaneous speech of five pairs of children who have undergone hemispherectomy, matching each pair for etiology and age at symptom onset, surgery, and testing. Our results show that following left hemispherectomy (LH), children evidence a greater error rate in the use of fun...
Article
Full-text available
This article presents a rationale and description of GCS, or Grammatical Coding System. GCS is a general-use grammatical coding system designed for research on the language of normal and language-impaired children or adults and is especially useful for studies in which a relatively large number of participants are involved. It implements recent the...
Article
To compare hemispherectomy patients with different pathologic substrates for hospital course, seizure, developmental, language, and motor outcomes. The authors compared hemispherectomy patients (n = 115) with hemimegalencephaly (HME; n = 16), hemispheric cortical dysplasia (hemi CD; n = 39), Rasmussen encephalitis (RE; n = 21), infarct/ischemia (n...
Article
We examined the morphosyntax of eight left hemispherectomized children at two different stages and compared it to MLU-matched normals. We found that the language of the hemispherectomies paralleled that of their MLU matches with respect to the specific morphosyntactic characteristics of each stage. Our findings provide strong evidence for the prese...
Article
A review of the literature on the developmental outcome of medically and surgically treated symptomatic infantile spasms (IS) indicates that poor seizure control, severe mental retardation, and marked behavioral disorders are found at long-term outcome of symptomatic IS. The 2-year outcome findings of the UCLA Pediatric Epilepsy Surgery Research Gr...
Article
We analyzed postsurgery linguistic outcomes of 43 hemispherectomy patients operated on at UCLA. We rated spoken language (Spoken Language Rank, SLR) on a scale from 0 (no language) to 6 (mature grammar) and examined the effects of side of resection/damage, age at surgery/seizure onset, seizure control postsurgery, and etiology on language developme...
Article
Full-text available
We investigated the categories of neural plasticity and the genesis of the neural representation for language in population of 43 pediatric hemispherectomies. We have chosen to correlate language outcomes with the stages of neuronal plasticity rather than age at insult because of the unavoidable confound between the latter and etiology (Curtiss and...
Article
We studied the spoken language of 49 children who had undergone hemispherectomy as part of the UCLA Pediatric Epilepsy Surgery Research Program and analyzed, among a number of clinical factors, the relation between acquired vs developmental pathology and spoken language outcomes. In this paper we will briefly review the results of our study and att...
Article
We report on the effects of etiology and age on the linguistic outcomes in a large pediatric hemispherectomy population. Four populations were considered separately: cortical dysplasia (multilobar involvement), Rasmussen's encephalitis, infarction as a primary etiology and, fourth, children who failed to develop language, regardless of etiology. We...
Article
this paper we will examine one aspect of grammatical development in children who have undergone hemispherectomy to control intractable epilepsy. Our objective is to investigate language development in children who have undergone hemispherectomy, the removal of one hemisphere of the brain, as a way to gain insight into the potential of each cortical...
Article
This study was designed to evaluate the effect of donor hyperosmolarity secondary to diabetes insipidus, an almost universal occurrence among brain-dead patients, on hepatic function. In vitro (isolated liver perfusion) and in vivo (hyaluronic acid and indocyanine green uptake, arterial ketone body ratio, orthotopic liver transplantation) experimen...
Article
Cytokines, produced by both the recipient and the newly vascularized allograft, are central mediators in the inflammatory response to allografted tissue. This study examines the relationship between pre- and intraoperative levels of TNF, IL-1, IL-6, and IL-8 and hepatic allograft function in the early postoperative period and also determines which...
Article
Full-text available
Evidence from a hearing-impaired woman after 13 years of language instruction & exposure (delayed until after her early 30s) supports the argument that grammar & number are distinct mental faculties, in contrast to James Hurford's analysis (1978, 1987), & that number cannot be bootstrapped from language as per Paul Bloom & Michael C. Corballis (199...
Article
This prospective case study examined social communication (i.e., formal thought disorder, cohesion), language, positron emission tomography glucose utilization, and neuropathology in four children with Rasmussen encephalitis who achieved seizure control following right hemispherectomy. Prior to hemispherectomy, all four children had illogical think...
Article
Primary dysfunction is a failure of graft function which occurs in approximately 5% of transplanted livers. Retransplantation is often required. The presence of elevated serum cytokines interleukin 6 and tumor necrosis factor with hepatic graft dysfunction, as well as the historical benefit of plasmapheresis in fulminant hepatic failure-associated...
Article
Samples of conversational language were elicited with a standardized interview protocol from 24 children, aged 2:6 to 7:8, half with specific language impairment (SLI), half with normally developing language (LN), matched for language level. Samples were analyzed to determine whether there were associations between adult questioning and children's...
Article
Full-text available
Investigate longitudinally the course of development of preschool learning impaired (LI) children to better understand the interaction between neurodevelopmental delay, behavioral/emotional disorders, and language development and disorders. Relationships between developmental language disorders and emotional problems were investigated in 99 8-year-...
Article
This study investigates whether language-impaired (LI) children show deficits in rapid automatized naming and whether RAN performance is specific to verbal output (or to rapid motor output in general). A total of 67 LI and 54 age-matched control children were tested with the Rapid Automatized Naming (RAN) test (Denckla & Rudel, 1976) and with a man...
Article
To investigate the issue of delay versus deviance in the language acquisition of language-impaired (LI) children, the order of acquisition of a set of linguistic structures and the relationship obtaining between one structure and another were examined in comprehension and production over a 5-year period in a group of LI and language-matched normal...
Article
This paper presents grammatical comprehension, computerized tomography (CT) and positron emission tomography (PET) data from a group of 43 aphasic patients. Comparison of comprehension performance with structural lesion (CT) revealed a correlation between comprehension of syntax and one inferior frontal lobe region (Broca's area) and one temporal l...
Article
Although etiological influences in developmental language impairment (dysphasia) are not well defined, a significant increase of family aggregation for the disorder has been reported. We report data from a large cohort of language-impaired (LI) children participating in the San Diego longitudinal study in which we examined whether children with or...
Article
The need for a standardized approach to the selection of research subjects for studies on language impairment has long been an area of controversy in the literature. The data obtained from the selection of language-impaired and control subjects for the San Diego Longitudinal Study allows one to evaluate the effects a two-stage subject-selection pro...
Article
Evaluated the extent to which school placement (SP) reflects differences in the language profiles and academic achievement outcomes of 89 language impaired 4 yr olds and determined what factors would best predict SP at 8 yrs old. Parents completed questionnaires for each year of the study, all Ss completed a questionnaire in the 1st yr, and selecte...
Chapter
In attempting to gain a better understanding of the pathogenesis of developmental dysphasia, research has focused on the associated characteristics of language-disordered children. These studies initially focused on the most obvious surface symptomatology, that is the linguistic dysfunction of these children. Subsequent studies have focused on nonl...
Article
Self-report data from the families of children participating in the San Diego Longitudinal Study of specific developmental language impairment were used to assess familial aggregation in the disorder. Families of impaired children reported higher rates of affected first-degree relatives than did families of matched controls. Significantly higher in...
Article
There is a well-documented propensity of males affected with developmental language/learning impairment. Results from this study demonstrate, unexpectedly, that this sex-ratio difference of males to females with developmental language/learning disorders was found to occur significantly only in families with a language/learning-impaired mother. In a...
Article
Previous research has suggested that language-impaired (LI) children have a high prevalence of psychiatric disorders, and conversely, that children being treated for psychiatric disorders have a high incidence of language impairment. To investigate the relationship between developmental language and psychiatric disorders further, the behavioral and...
Article
Full-text available
Language ability of 20 patients with probable Alzheimer's disease (AD) was evaluated. Analysis of spontaneous speech revealed a normal range and frequency of syntactic constructions but poor lexical use. A writing task showed a similar divergence, with the ability to use syntactic cues significantly more intact than the ability to use semantic cues...
Article
An important issue for the cognitive sciences is whether grammar is to any nontrivial extent an autonomous cognitive system. Current cognitive hypotheses of language acquisition would argue against an autonomous linguistic system and would support the notion that language emerges from more general cognitive knowledge and is throughout its developme...
Article
The purpose of the study was to characterize the early pragmatic-semantic communicative development of young hearing-impaired children learning spoken English as a first language. Twelve children with impaired hearing, ranging in age from 22 months to 60 months, were videotaped. Approximately 13 hours of videotaped data from four different communic...
Chapter
This chapter presents a case history of Genie's condition during January 1971–June 1971. As of January 1971, Genie appeared to have a small receptive vocabulary and an even smaller productive vocabulary. Her spontaneous productive vocabulary included the terms stopit and nomore. During the months from January through June of 1971, Genie changed soc...
Chapter
This chapter presents a case history of Genie's condition during November 1970–January 1971. Genie was pitiful when she was admitted into the hospital. In November 1970, Genie was given the Vineland Social Maturity Scale and the Preschool Attainment Record, the scores of which were mental age (MA) 1.05 years and MA 13 months, respectively. In Janua...
Chapter
This chapter discusses the extent of Genie's comprehension of English, from the time she entered the hospital in November 1970, through the following 4.5 years. It presents evidence from videotapes on Genie's comprehension during the first weeks after her emergence. The nondominant hemisphere for language understands language only outside of the ri...
Chapter
This chapter focuses on phonological perception, that is, receptive phonological abilities and discusses aspects of Genie's phonological knowledge and abilities. Genie's phonological system is abnormally variable and unpredictable. Almost all the rules are optional, and many of the substitutions and deletions distort the phonological structure to a...
Chapter
This chapter presents a comparison of Genie's language acquisition to that of normal children acquiring a first language. Genie's acquisition of phonology paralleled normal phonological development in several respects such as her deletion of final consonants, simplification of initial clusters, relatively late use of affricates, and deletion of uns...
Article
This paper discusses the linguistic development of Genie, an adolescent girl who for most of her life underwent a degree of social isolation and experiential deprivation unparalleled in the reports of scientific investigation. This case touches on questions of profound interest to psychologists, philosophers, and linguists, including the relationsh...
Article
One dichotic listening experiment studying hemispheric specialization for pitch in a linguistic context (Thai) (Van Lancker and Fromkin, 1973) found a right?ear advantage for words that are differentiated by tone only; in another study (Cantonese) (Benson, Smith, and Arreaga, 1973) no ear advantage was found for perception of tone in words. Both st...
Article
The present paper reports on a case of a now-16-year-old girl who for most of her life suffered an extreme degree of social isolation and experiential deprivation. It summarizes her language acquisition which is occurring past the hypothesized “critical period” and the implications of this language development as related to hemispheric maturation a...
Article
This abstract will describe a grammatical coding and analysis system devised to study language development in normal and brain-damaged chil-dren, but which can be used to analyze mature as well as developing grammars. The research project for which this system was developed investigates the lateralization and loca-lization of language in its develo...
Article
Thesis--University of California, Los Angeles. Includes bibliographical references (leaves 654-669). Photocopy of typescript. Ann Arbor, Mich. : University Microfilms International, 1977. -- 21 cm.

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