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Surya Prakash Gupta

Surya Prakash Gupta
AKS University, Satna (M.P.) · Department of Pharmaceutical Science & Technology

M.Pharm (Pharmaceutical Chemistry), Ph.D.

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26
Publications
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174
Citations

Publications

Publications (26)
Article
ABSTRACT The present research has been undertaken with the aim to design, formulate and evaluate the polyherbal Tridax procumbens based cream comprising of Aloe vera, Marigold, Henna, Papaya and Neem. The cream was evaluated for pharmaceutical parameters & wound healing activity. The cream was formulated using accurately weighed amount of drug extr...
Article
Full-text available
Society of Pharmacovigilance, India (SoPI) was established in 2000 with an objective to foster science and learning in the discipline of pharmacovigilance. The society fulfils this aim by providing opportunities for networking in a friendly environment, collegial and convivial support among fellow pharmacovigilance professionals and members, open a...
Article
In the few decades, there has been exponential growth in the field of herbal medicines. Most of the traditional system of medicine is effective but they lack standardization. So there is a need to develop a standardization technique. Standardization of herbal formulation is essential in order to assess the quality, purity, safety and efficacy of th...
Article
A simple and reproducible UV- spectrophotometric method for the quantitative determination of Tannic acid in Bhuvnesvara vati (BV) were developed and validated in the present work. The parameters, precision, accuracy, Limit of Detection and Limit of Quantitation were studied. In this present study a new, simple, rapid, sensitive, precise and econom...
Article
A QSAR study of triazole-linked chalcone and dienone hybrid compounds as antimalarial agents was performed with 38 (33 training + 5 test) compounds. Molecular modeling studies were performed using chemoffice 6.0 supplied by cambridgesoft. The structures were drawn using chemdraw and were converted to 3D. Energy was minimized and the lowest energy s...
Article
Full-text available
Product development of ophthalmic preparations has received considerable attention in the last few years. With the increasing emphasis on their sterility, some of the differences between them and parenteral preparations are becoming less evident. Both classes of preparations employ similar added substances and manufacturing procedures. The successf...
Article
Full-text available
The aim of present study is to develop biodegradable microspheres of Tinidazole. Bovine Serum Albumin was used for the preparation of microspheres. They were made in four batches. The emulsion cross-linking method was used for the preparation. The quantity of BSA varies for each formulation. Formulations were evaluated for particle size, Melting po...
Article
Several 3-substituted 1,2-benzisoxazole derivatives were synthesized from treatment of 4-amino- 2-hydroxy acetophenone by different aldehyde substitution with the hope that different substituent formed at the third position show significant antimicrobial activity. 4-amino-2-hydroxy acetophenone 1 on treatment with different aldehydes 2a-e in sodium...
Article
In recent years, there have been increased efforts to find safer and effective drugs to treat various ocular conditions as well as to develop novel dosage forms and delivery systems to improve the topical delivery of existing drugs. Today, topical ophthalmic application is considered the preferred way to achieve therapeutic levels of the drug used...
Article
The present study describes the newer cost-effective formulation of metformin extended release tablets. Metformin is one of the widely used drugs for the management of type-II diabetes and is a large dose drug. The total average weight of the commercially available tablets was more than 750 mg. Size reduced oral extended release tablets were meant...
Article
To study the immunomodulatory property of the leaves of Gymnema sylvestre R.Br. (Asclepiadaceae). In our present study, the aqueous extract of Gymnema sylvestre leaves was investigated for immunomodulatory activity by assessing Neutrophil locomotion and chemotaxis test, phagocytosis of killed Candida albicans and Nitroblue terazolium tests. The ext...
Article
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The leaves of Murraya koenigii (L) Spreng (Rutaceae) are reported to have great medicinal value. Pharmacognostic evaluation including examinations of morphological and microscopic characters, determination of leaf content, ash value, powder analysis, and extractive values were carried out. Phytochemical screenings including qualitative chemical exa...
Article
Full-text available
The ethanomedicinal plant Murraya koenigii Linn. is a common ingredient in indian curry. Phytochemically, leaves of the plant are found to contain various biomolecules effective against various diseases and disorders. In present work, dried bark powder subjected to solvent extraction method using different organic solvents. After phytochemical scre...
Article
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Hair formulation of Emblica officinalis (Euphorbiaceae), Bacopa, monnieri (Scrophulariaceae), Trigonella foenumgraecum (Leguminosae), Murraya koenigii (Rutaceae) in various concentrations in the form of herbal oil were studied for their hair growth activity. Each drug was tested for their hair growth activity in a concentration range for 1-10% sepa...
Article
Full-text available
A novel series of 6-amino uracil base analogue were synthesized. QSAR study was used to relate the selective nonsubstrate inhibitory activity of 6-amino uracil base analogue with various physicochemical descriptors. Stepwise multiple regression analysis was performed to find out the correlation between various physicochemical descriptors and biolog...
Article
A number of quinoxaline-2-ones analogues have been synthesized by condensation of parent compound with different acid chlorides and screened for antibacterial activity against Escherichia coli, Bacillus subtilis, Bacillus cereus and Staphylococcus aureus and antifungal activity against Aspergillus niger and Candida species and analgesic activity. T...
Article
Stepwise multiple regression analysis was performed to find out the correlation between various physicochemical descriptors and biological activity of the compounds by using Openstat 2 version 6.5.1 and Valstat statistical software. Out of the several equations developed, the best equations having the highest significance were selected for further...
Article
Azoles are important five membered heterocyclic rings containing at least onenitrogen atom like Isoxazole, Thiazole, Pyrazole and Triazole. Hence we concentrateon 1,2,4-Trizoles, which possess three nitrogen in five membered heterocyclicring and show various medicinal properties such as possible hypoglycaemic activity,Antimicrobial, Antiinflammator...
Article
QSAR study was used to relate the tubulin inhibitory activity of 2-Aroylindole derivatives with various physicochemical descriptors. Stepwise multiple regression analysis was performed to find out the correlation between various physicochemical descriptors and biological activity of the compounds by using Openstat 2 version 6.5.1 and Valstat statis...
Article
An attempt has been made to provide upto date references that are categorized on the basis of phytochemical and pharmacological basis.

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