Surajit Majumder

Surajit Majumder
Bankura Sammilani College · Department of Zoology

Dr. Surajit Majumder, Ph.D.

About

22
Publications
6,789
Reads
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359
Citations
Additional affiliations
April 2010 - present
Bankura Sammilani College
Position
  • Professor (Assistant)
February 2002 - March 2006
Chittaranjan National Cancer Institute
Position
  • J.R.F. & S.R.F.

Publications

Publications (22)
Article
Full-text available
The Bankura town of district Bankura, West Bengal, India is full of lentic water bodies like pond, reservoir and water tank etc. In these lentic water bodies, some are perennial. Most of the rest waterbodies are seasonal. Out of these, a large number of waterbodies are partly seasonal; that means, these waterbodies can retain the water to some exte...
Article
Full-text available
The alarming pandemic situation of corona virus disease (COVID-19) outbreak arises due to rapid spread of Novel Corona Virus (SARSCoV-2). Impaired redox homeostasis in association with oxidative stress is found to be important biological processes that may account for increased individual susceptibility to COVID-19 infection. Glutathione (GSH) is o...
Article
Full-text available
Fish is a substantial element of both culture and emotion of Bengalis. Unfortunately, fish production does not reach the limit of its requirement in West Bengal, so we have to import fish from different states like Andhra Pradesh, Bihar, Karnataka, Tamil Nadu. The Bankura district of West Bengal is full of static water bodies like ponds, reservoirs...
Article
Full-text available
Eutrophication, an anthropogenic nutrient enrichment is a common phenomenon in enclosed waterbodies like ponds which can be found in the maximum part of West Bengal, India. The Bankura district of West Ben-gal is full of static water bodies like pond, reservoir, water tank. But in Bankura town the pisciculture is less efficient due to various natur...
Article
Full-text available
Water is the main source of survival for all the living organisms. Still people use it in a very casual way. As a result of unaware use of water, some changes have taken place in physico-chemical parameters followed by plankton diversity of pond and river water of Bankura district, West Bengal, India. The district Bankura has ranked first in piscic...
Article
Full-text available
Pisciculture is a proficient commercial means of upkeep for rurals of Bankura district (par-ticularly in Onda Block of Ramsagar village) of West Bengal, India. Due to various natural and anthropo-genic causes, fish mortality has become a great trouble of Bankura town nowadays. In this present study we have tried to find out the causes of fish morta...
Article
Full-text available
The Bankura district of West Bengal is with full of static water bodies like pond, reservoir, water tank etc. Most of these water bodies are being used by local residents for their daily purposes and some are also used for economic purposes such as fish culture. The unaware use of water causes some changes in physico-chemical parameters of some pon...
Article
Full-text available
The Bankura district of West Bengal is with full of static water bodies like pond, reservoir, water tank etc. Most of these water bodies are being used by local residents for their daily purposes and some are also used for economic purposes such as fish culture. The unaware use of water causes some changes in physico-chemical parameters of some pon...
Article
Full-text available
The Bankura district of West Bengal is with full of static water bodies like pond, reservoir, water tank etc. Most of these water bodies are being used by the local residents for their daily purposes. The unaware use of water causes some changes in physico-chemical parameters of some ponds of Bankura town. This project work reveals the fact that, h...
Article
Full-text available
The Bankura district of West Bengal is with full of static water bodies like pond, reservoir, water tank etc. Most of these water bodies are being used by the local residents for their daily purposes. The unaware use of water causes some changes in physico-chemical parameters of some ponds of Bankura town. This project work reveals the fact that, h...
Article
Full-text available
Present study focused on the spatial and seasonal variations in the physico-chemical parameters of the river Dwarakeshwar passing through district Bankura of West Bengal, India. A total of seven parameters were analysed and their seasonal variations are observed to assess the impact of effluents of Bankura town on the water quality. The sampling wa...
Article
Full-text available
Glutathione (GSH), an important component of the phase II detoxification system, plays a major role in storage, metabolism and transport of metals across the cell membrane. The role of copper, its metabolism and storage in living systems is not completely understood. Copper plays an important role in a number of physiological processes, e.g. severa...
Article
Full-text available
Multidrug resistance (MDR) is still a major threat to successful clinical application of cancer chemotherapy. Copper plays an important role in biological systems, and copper is also involved in carcinogenesis. In the present investigation, we addressed the question whether metal copper might be involved in drug resistance of murine and human tumor...
Article
Full-text available
Multiple drug resistance (MDR) represents a major obstacle to successful application of chemotherapy and a basic problem in cancer biology. MDR occurs at the cellular level and is multi-factorial in nature. The multidrug resistance gene, MDR1, and its gene product P-glycoprotein (P-gp) are now well known as an important determinant of MDR. Much eff...
Article
Full-text available
Previously, we have synthesized and characterized a novel Cu(II) complex, copper N-(2-hydroxy acetophenone) glycinate (CuNG). Herein, we have determined the efficacy of CuNG in overcoming multidrug-resistant cancer using drug-resistant murine and human cancer cell lines. Action of CuNG following single i.m. administration (5 mg/kg body weight) was...
Article
Full-text available
One of the important pathways of resistance to anthracyclines is governed by elevated levels of glutathione (GSH) in cancer cells. Resistant cells having elevated levels of GSH show higher expression of multidrug-resistant protein (MRP); the activity of glutathione S-transferases (GSTs) group of enzymes have also been found to be higher in some dru...
Article
Full-text available
In search of a suitable GSH-depleting agent, a novel copper complex viz., copper N-(2-hydroxyacetophenone) glycinate (CuNG) has been synthesized, which was initially found to be a potential resistance modifying agent and later found to be an immunomodulator in mice model in different doses. The objective of the present work was to decipher the effe...
Article
Full-text available
Multidrug resistance (MDR) is a major obstacle to successful application of cancer chemotherapy and also a basic problem in cancer biology. Studies on the molecular basis of MDR have revealed that a number of proteins over express in multidrug resistant cells viz., multidrug resistant MDR1 gene product P-glycoprotein, the multidrug resistance-assoc...
Patent
Full-text available
Abstract: A novel Cobalt useful for reversal of drug resistance, said cobalt complex having the general formula 1: OH2 O Co O Ar N C ===O C R (CH2)n Wherein “Ar” is selected form substituted or unsubstituted phenyl group, substituted or unsubstituted napthyl group and substituted and unsubstituted anthracene group; “R” is selected from methyl or et...
Article
Full-text available
Development of biochemical modulators and application of the same with anticancer drugs is a current approach of modern cancer chemotherapy. We report the effect of two novel hydroxamic acid derivatives, viz. oxaly bis (N-phenyl) hydroxamic acid (OBPHA) and succinyl bis (N-phenyl) hydroxamic acid (SBPHA) on doxorubicin sensitivity and on P-glycopro...
Article
Full-text available
The study of copper complex in relation to cancer is important in many ways. A novel copper complex has been synthesized with non toxic ligand, viz. potassium salt of N-(2-hydroxy acetophenone) glycinate (NHAG). The structure of the complex has been determined by spectroscopic means. Toxicity and antitumor property of the complex has been studied i...

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