Suprabhat Giri

Suprabhat Giri
Nizam's Institute of Medical Sciences · Department of Medical Gastroenterology

DM (Gastroenterology)
Vascular liver disease, Portal hypertension, EUS, Interventional endoscopy

About

90
Publications
6,176
Reads
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26
Citations
Additional affiliations
October 2020 - October 2021
King Edward Memorial Hospital
Position
  • Professor (Assistant)
Education
September 2017 - September 2020
King Edward Memorial Hospital
Field of study
  • Gastroenterology

Publications

Publications (90)
Article
Full-text available
Background Underwater endoscopic mucosal resection (uEMR) without submucosal injection for sessile colorectal polyps was introduced as a newer replacement for conventional EMR (cEMR). However, the optimal resection strategy remains a topic of debate. Hence, this meta-analysis was conducted to compare the efficacy and safety of uEMR and cEMR in pati...
Article
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Background and study aims Clinical practice patterns for image-enhanced endoscopy (IEE) and colonic endoscopic resection practices vary among endoscopists. We conducted a survey to understand the differences in IEE and colonoscopic resection practices among endoscopists from India. Methods An online cross-sectional survey comprising 40 questions re...
Article
An array of pathophysiological processes can lead to chronic nausea and vomiting, including gastrointestinal and non-gastrointestinal disorders. Initial symptoms of adrenal insufficiency are usually non-specific, but intractable nausea and vomiting are infrequently associated, posing a diagnostic dilemma for clinicians. Here we present such a patie...
Conference Paper
Full-text available
Background A common indication for performing an endoscopic retrograde cholangiopancreatography (ERCP) is the removal of biliary stones. Although the majority of cases are amendable to clearance of the biliary system during a single session, there remains a portion where repeated procedures are required, due to factors pertaining to the anatomy of...
Conference Paper
Background Ascites is the most common complication of decompensated liver cirrhosis requiring paracentesis for diagnostic and therapeutic purposes. An ascitic fluid leak can develop after paracentesis in patients with cirrhosis leading to significant morbidity if persistent. We aimed to study the incidence and predictors of post-paracentesis leak i...
Conference Paper
Background Malnutrition is common in cirrhotics with a 50 – 90% prevalence and is an important prognostic factor. An ideal assessment tool is unclear due to confounders like ascites and edema. The role of sophisticated nutritional assessment tools is also controversial. Hence, this study was conducted to assess the nutritional status in cirrhotics...
Conference Paper
Background The diagnosis of intraparenchymal lung masses is challenging when lesions are located at sites inaccessible through bronchoscopy or endobronchial ultrasound. Endoscopic ultrasound (EUS)-guided tissue acquisition [fine-needle aspiration (FNA) or fine-needle biopsy (FNB)] provides a potentially useful diagnostic tool for lesions located ad...
Article
Full-text available
Objectives Hepatitis B virus (HBV) infection during pregnancy is associated with perinatal transmission contributing to the pool of HBV infection in the population. There is a wide variation in the reported data on the seroprevalence of hepatitis B virus in pregnant patients from various parts of India. Hence, a systematic review and meta-analysis...
Article
Full-text available
Backgrounds/aims: Endoscopic retrograde cholangiopancreatography (ERCP) remains the primary treatment for a subset of patients with pancreatic fistulae. The objective of this study was reporting outcomes of ERCP and predictors of resolution in patients with pancreatic fistulae refractory to conservative therapy. Methods: Retrospective review of...
Article
Purpose The data with respect to the safety and outcome of transjugular intrahepatic portosystemic shunt (TIPS) in patients with Budd-Chiari syndrome (BCS) are scarce due to the rarity of the disease. Hence, this meta-analysis was conducted to assess the critical role of TIPS in the management of BCS. Methods A comprehensive search of literature...
Article
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Biliary self-expanding metal stents (SEMSs) are most commonly used for establishment of drainage in case of malignant biliary obstruction. The most common complication associated with these stents is migration, which is usually distal. However, proximal migration of SEMS is less common. Here, we present a case of malignant extrahepatic biliary obst...
Article
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Objectives Shunt surgery is the definitive treatment for symptomatic patients with portal cavernoma cholangiopathy (PCC), but few patients are non-surgical candidates or fail to improve even after surgery. This study aims to analyze the long-term outcomes of endoscopic therapy in these patients. Methods Retrospective review of a prospectively main...
Article
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LINKED CONTENT This article is linked to Brandman et al papers. To view these articles, visit https://doi.org/10.1111/apt.16874 and https://doi.org/10.1111/apt.16972
Poster
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Introduction: Alcohol is the commonest etiology of cirrhosis in India and decompensation of liver cirrhosis with jaundice, ascites, variceal bleeding or hepatic encephalopathy is a critical point in the natural history of cirrhosis associated with increased morbidity and mortality. This study aims to analyze the outcome of patients with alcoholic c...
Article
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Pregnancy in non-cirrhotic portal hypertension (NCPH) is an uncommon condition. Its management is challenging both to the obstetricians as well as to the gastroenterologists due to the lack of more extensive studies and standard clinical practice guidelines. These patients are at increased risk of portal hypertension (PHT) complications, especially...
Article
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Hepatocellular carcinoma (HCC) is the most common cause of, and accounts for almost 90% of all liver cancers. Data from India is limited especially due to cancer not being a reportable disease and in view of wide variation in diagnostic modalities. This document is a result of a consensus meeting comprising Hepatologists, Interventional Radiologist...
Article
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Optimal endoscopic management of benign biliary strictures (BBS) has been a matter of debate with choice of stent remaining largely at the discretion of the endoscopist. In this systematic review and meta-analysis, we compared self-expanding metal stents with multiple plastic stents for benign biliary strictures. A comprehensive search of literatur...
Article
We read with great interest the recent article by Marmo et al,1 comparing the outcome of acute upper gastrointestinal bleeding (AUGIB) in patients using antithrombotic agents (ATs) with patients who were not on AT therapy. Mortality, rebleeding, and need for surgery or radiologic intervention were similar between both groups. On multivariate analys...
Article
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Aim: Low anterior resection (LAR) and intersphincteric resection (ISR) are the standard surgical options for low and very low rectal cancers, respectively. Unlike LAR, dissection in between the internal and external sphincter in ISR may functionally compromise sphincter integrity post-surgery.The aim was to compare anal sphincter function using ano...
Article
Full-text available
LINKED CONTENT This article is linked to Higuchi et al papers. To view these articles, visit https://doi.org/10.1111/apt.16745 and https://doi.org/10.1111/apt.16791
Article
To the Editor, We read with great interest the recently published article by Garg et al. [1], reporting the outcome of gastrointestinal bleeding (GIB) in patients with end-stage renal disease (ESRD) based on the data of GIB from the National Inpatient Sample (NIS) database. The authors reported a significantly higher mortality rate and higher healt...
Article
Background and Objective: There are limited data on the adverse events of D-penicillamine in Wilson's disease (WD) that can result in dose modification or treatment discontinuation. The objective of this study was to observe the adverse events related to D-penicillamine in patients with hepatic WD. Methods: A retrospective audit of prospectively r...
Article
We read with great interest the recently published article by Kale et al. [1] on hepatic tuberculosis (HTB) mimicking as neoplastic liver lesions leading to diagnostic dilemma. The most common mimicker was cholangiocarcinoma (CCA) (58%), followed by liver metastasis (26%) and lymphoma (7%). Six patients had already undergone hepatic resection with...
Article
Full-text available
• Pregnancy-associated liver diseases are the most common causes of liver dysfunction during pregnancy affecting both maternal and fetal outcomes. • While hyperemesis gravidarum and intrahepatic cholestasis of pregnancy are usually associated with a benign course, preeclampsia with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndro...
Article
Endoscopic therapy is the first-line definitive therapy for acute variceal bleeding (AVB) in patients with portal hypertension (PHT) [ [1] ]. However, there is controversy regarding the optimal timing of endoscopy in both adults and pediatric populations due to the lack of prospective studies. Early endoscopy (within 12 h) for variceal bleeding is...
Article
Background Ascites is the most common complication of decompensated cirrhosis of liver requiring paracentesis for diagnostic and therapeutic purpose. Ascitic fluid leak can develop after paracentesis in patients with cirrhosis leading to significant morbidity if persistent. We aimed to study the incidence and predictors of post-paracentesis leak in...
Article
We read with great interest the article by Rajakannu et al. on the prediction of hepatic venous pressure gradient (HVPG) using a model based on preoperative liver stiffness measurement (LSM), liver function test, and international normalized ratio. The authors concluded that this model named as HVPG10 score can rule out clinically significant porta...
Article
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In the recently published original article by Paternostro et al., analyzing the prognostic value of HVPG-response to (NSBB) in patients with NASH-related cirrhosis and varices, the authors reported that 55.3% of the patients achieved HVPG-response to NSBB. Presence of diabetes (adjusted odds ratio (aOR) 0.16, p = 0.038) and baseline mean arterial p...
Article
We read with great interest the original article by Decraecker et al. [1] comparing the long‐term outcome of patients with alcoholic liver disease (ALD) and non‐alcoholic fatty liver disease (NAFLD) according to the degree of alcohol use and presence of the metabolic syndrome. The authors need to be congratulated for conducting this study with a pr...
Article
In a recently published systematic review and meta-analysis by Bhurwal et al., comparing the difference in the outcome of 6- to 9- and ≥ 9-min colonoscopy withdrawal time (CWT). The authors reported that CWT of ≥ 9 min was associated with a higher odd of adenoma detection, sessile serrated adenoma detection, and advanced adenoma detection compared...
Article
Full-text available
Background Wilson’s disease is a multisystem disorder with predominant clinical symptoms depending on the site of copper deposition in the body. Hepatic presentation is usually seen in the younger age group. And pancreatitis is rarely associated with Wilson’s disease. To the best of our knowledge, recurrent acute pancreatitis as a presenting manife...
Article
We read with great interest the original article by Decraecker et al. [1] comparing the long‐term outcome of patients with alcoholic liver disease (ALD) and non‐alcoholic fatty liver disease (NAFLD) according to the degree of alcohol use and presence of the metabolic syndrome. The authors need to be congratulated for conducting this study with a pr...
Article
Renzulli et al. evaluated the prognostic role of CT features in cirrhotic patients with portal hypertension to predict the risk of hepatic decompensation. The authors reported the presence of spontaneous portosystemic shunts, a spleen diameter >16 cm, a portal vein diameter >17 mm, and ascites to be independent predictors of decompensation-free sur...
Article
We read with great interest the original article by Patidar et al. [1], studying the outcomes associated with intravenous (IV) albumin in patients with cirrhosis and acute kidney injury (AKI). The authors reported that albumin use was not associated with AKI-recovery or in-hospital survival compared to crystalloids. However, there are a few issues...
Article
Full-text available
Patients with cirrhosis of liver are at high risk of developing PV thrombosis (PVT), which has a complex, multifactorial cause. The condition may present with a myriad of symptoms and can occasionally cause severe complications. Contrast-enhanced computed tomography (CT) is the gold standard for the diagnosis of PVT. There are uncertainties regardi...
Conference Paper
Full-text available
Background and aims: Extrahepatic portal vein obstruction (EHPVO) is a heterogenous disease with regards to etiology, pathogenesis, age, and geographical location. EHPVO is the second most common cause of portal hypertension in India after cirrhosis, responsible for 35-40% cases of variceal bleeding. Although umbilical vein catheterization or ompha...
Conference Paper
Full-text available
Background: Budd Chiari syndrome (BCS) may present as acute on chronic liver failure (ACLF). However, there is paucity of data with regards to the outcomes and its predictors. Methods: We conducted this multi-center study by analyzing a prospectively collected data across the Asia Pacific region. Consecutive patients with BCS presenting as acute-o...
Article
Full-text available
Pancreatic strictures represent a complex clinical problem which often requires multidisciplinary management with a team of gastroenterologists, surgeons and radiologists. Dominant strictures are largely due to inflammatory processes of the pancreas like chronic pancreatitis. However, differentiating benign from malignant processes of the pancreas,...
Conference Paper
Full-text available
Background and Aim: Anomalous pancreatobiliary duct union (APBDU) is defined by abnormal position of union of bile duct (BD) and pancreatic duct (PD), outside duodenal wall above influence of sphincter of Oddi. APBDU may rarely present as recurrent acute pancreatitis (RAP) or chronic pancreatitis (CP).We assessed the response to endotherapy in pati...
Article
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Budd Chiari syndrome (BCS) is a diverse disease with regard to the site of obstruction, the predisposing thrombophilic disorders and clinical presentation across the Asia-Pacific region. The hepatic vein ostial stenosis and short segment thrombosis are common in some parts of Asia-Pacific region, while membranous obstruction of the vena cava is com...
Article
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Background/aims: Pancreatic strictures in chronic pancreatitis are treated using endoscopic retrograde cholangiopancreatography (ERCP) with plastic stent placement. The management of recalcitrant strictures remains a challenge, with the use of a Soehendra stent retriever or a needle knife described in case reports. Here, we discuss our experience...
Article
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Background/Aims: Bile leak is a common complication of cholecystectomy, and it is also observed in other conditions such as ruptured liver abscess, hydatid cyst, and trauma. Endoscopic retrograde cholangiopancreatography (ERCP) is the first-line management for such conditions. However, studies on the outcomes of endoscopic management for bile leaks...
Article
Full-text available
Background The majority of foreign bodies entering the small intestine are passed spontaneously. However, in case of a sharp object, its removal is an urgency due to a higher risk of intestinal perforation, and endoscopic intervention is an appropriate management strategy as surgery is associated with greater morbidity. Although enteroscopy is the...
Conference Paper
Full-text available
Background and Aims Bile leak is a known complication of cholecystectomy but is also seen in other conditions such as a ruptured liver abscess, post-surgery for hydatid cyst and trauma. Endoscopic retrograde cholangiopancreatography (ERCP) has evolved as the first line of management for such patients but very few studies have studied the outcome in...
Conference Paper
Full-text available
Introduction: SBP is a complication of decompensated cirrhosis, and is associated with poor survival and need for liver transplantation. Nosocomial SBP is associated with infection due to antibiotic-resistant organisms. We studied the predictors of short term mortality in patients with SBP. Methodology: A retrospective review of patients admitted...
Conference Paper
Background EGJOO is characterized by impaired relaxation of EGJ with intact or weak peristalsis. It includes a heterogeneous group of various etiologies. In most instances, no specific etiology is found. We present the characteristics of patients with diagnosis of EGJOO outflow obstruction on HRM their outcomes with conservative management. Meth...
Article
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Background: Microalbminuria is a major risk factor predisposing to cardiovascular morbidity and mortality but very limited evidence are there to suggest it's use as a prognostic tool to determine in-hospital morbidity and mortality. The aim of this study was to examine the presence of microalbuminuria as a predictor of major adverse cardiac events...