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Publications
Publications (12)
The accurate and timely diagnosis of COVID-19 has played a pivotal role in controlling the spread of SARS-CoV-2 and managing the pandemic. This review examines the evolution of diagnostic methods, from initial molecular and immunoassay techniques to advanced innovations. Through systematic analysis of the existing literature, regulatory frameworks,...
Carbon nanotubes (CNTs) have emerged as revolutionary tools, offering innovative approaches to both diagnostic and therapeutic challenges spanning various cancer types. CNTs serve as imaging agents for early detection through MRI, CT, and fluorescence. They provide precise results with biosensors detecting cancer biomarkers for rapid diagnosis. In...
The COVID-19 outbreak has created disaster globally, and mankind is yet to come in terms with combating this global menace. Amid this turmoil, immunocompromised individuals like cancer patients exhibit dismal immune responses toward such infection. In order to treat cancer patients during such adverse situations, it is necessary to understand the p...
Glioblastoma multiforme (GBM) is a highly aggressive form of primary brain tumor in adults, which unfortunately has an abysmal prognosis and poor survival rates. Even though several FDA-approved multimodal treatments for targeting GBM are available, the effectiveness in most patients are not satisfactory. The reason behind this poor success rate is...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes the complicated disease COVID-19. Clinicians are continuously facing huge problems in the treatment of patients, as COVID-19-specific drugs are not available, hence the principle of drug repurposing serves as a one-and-only hope. Globally, the repurposing of many drugs is underway;...
Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2)‐induced COVID‐19 is a complicated disease. Clinicians are continuously facing difficulties to treat infected patients using the principle of repurposing of drugs as no specific drugs are available to treat COVID‐19. To minimize the severity and mortality, global vaccination is the only ho...
Maintaining the balance between eliciting immune responses against foreign proteins and tolerating self-proteins is crucial for maintenance of homeostasis. The functions of programmed death protein 1 (PD-1) and its ligand programmed death ligand 1 (PD-L1) are to inhibit immune responses so that over-reacting immune cells does not cause any damage t...
The carboxy-terminus of Hsp70-interacting protein (CHIP) is a ubiquitin ligase and co-chaperone belonging to Ubox family that plays a crucial role in the maintenance of cellular homeostasis by switching the equilibrium of the folding-refolding mechanism towards the proteasomal or lysosomal degradation pathway. It links molecular chaperones viz. HSC...
