
Sunishtha YadavAmity Institute of Biotechnology/Indian Institute of Toxicology Research · Biosciences
Sunishtha Yadav
PhD
About
22
Publications
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731
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Introduction
Skills and Expertise
Additional affiliations
November 2010 - present
Amity Institute of Biotechnology, Amity University, Noida, India
Position
- Professor (Assistant)
August 2005 - July 2009
Education
August 2005 - July 2009
Publications
Publications (22)
Cancer has been known as a devastating disease that takes thousands of lives every year. And since this is a heterogenous disease, standard treatments, like chemotherapy, radiation, and chemo-radio therapy, are effective in specific patient population subset only. Genetic differences play a very crucial role in defining cancer susceptibility and al...
Drug discovery is the process in which healthcare is approached through identification of potential new therapeutic agents. CADD provides solutions at every stage of drug discovery including the leading challenges of cost and time. CADD has provided an effective solution to this challenge. AI has enabled multiple aspects of drug discovery, includin...
The COVID-19 pandemic has been an eye-opener towards human lifestyle and the healthcare sector. During this phase, a new factor witnessed by humankind is the economic and social impact of the healthcare sector. Due to this rising concern in the healthcare sector, new market segments, niches, and micro-niches are created, which have given some abund...
Functionalization of nanoscale (<100 nm) particles at the cellular level is highly specific and can be employed to develop efficient diagnostic and therapeutic procedures with the minimum of side effects. The binding of nanosized particles (quantum dots, iron oxide nanocrystals, nanowires, and nanotubes) with ligands creates varied optical, magneti...
Small heat shock proteins as large multigene family are present ubiquitously among Archaea to Eukaryota. The sHSPs are molecular chaperones that maintain the proper protein folding and disaggregation of denatured proteins during stress conditions. In the present study, out of identified 38 sHSPs in the pigeonpea genome, the 20 are distributed acros...
Key message
Comparative transcriptome analyses accompanied by biochemical assays revealed high variability in heat stress response inCajanusspecies. Among the studied species,C. scarabaeoides was the most thermotolerant followed byC. cajanifolius,C. cajan, andC. acutifolius.
Abstract
Pigeonpea is one of the climate-resilient grain legumes. Though...
Large clusters of patients were reported with pneumonia such as symptoms of unknown causes, all linked to a seafood, and wet animal wholesale market in the city of Wuhan, Hubei Province, China in December 2019. This was followed by studies conducted by the Chinese authorities leading to the detection of a novel strain of coronavirus named as 2019-n...
Cancer has been known as a devastating disease that takes thousands of lives every year. And since this is a heterogenous disease, standard treatments, like chemotherapy, radiation, and chemo-radio therapy, are effective in specific patient population subset only. Genetic differences play a very crucial role in defining cancer susceptibility and al...
As paper has become an important part of global consumption, there is a necessity to find a balance between production and resources, when an increase in paper production has been observed within past decades. Diverse technologies are being used for paper production one of them being use of enzyme of microbial origin for better bio-pulping and bio-...
The present paper will highlight the impact of COVID-19 on different sectors like cancer care and cancer patient’s management and on the education system. With this pandemic, almost all the sectors have been affected badly but the major impact is visible on health care and education system because both these sectors demands face-to-face interaction...
During the COVID-19, the cancer care is one of the most effected fields. The cancer care is either delayed or discontinued during the pandemic because of which cancer patients had to face resource constrain. Limited resources availability during this pandemic led to delay in the cancer diagnosis, undetected/ untreated cases and worse prognosis. The...
COVID-19 outbreak has caused a downward spiral in the world economy and caused a huge impact on the higher education system. The sudden closure of campuses as a social distancing measure to prevent community transmission has shifted face-to-face classes to online learning systems. This has thrown the focus on utilising eLearning tools and platforms...
Aim: The present study aimed to identify the poor metabolizers (PMs) genotype of CYP2D6 & their effect on treatment outcomes in HNSCC cases.
Methods: This case-control study comprised 375 male cases with head and neck squamous cell carcinoma (HNSCC) and an equal number of healthy controls from the same ethnic group (Indo-European community) of Nort...
The present case–control study involving 750 cases and equal number of healthy controls investigates the association of polymorphism in cytochrome P450 2C9 (CYP2C9) with head and neck squamous cell carcinoma (HNSCC) and response in patients receiving chemotherapy or combination of radio-chemotherapy. The frequency of heterozygous or homozygous geno...
The present case-control study attempted to investigate the association of poor metabolizer (PM) genotypes of cytochrome P450 2D6 (CYP2D6*4 and CYP2D6*10) with squamous cell carcinoma of head and neck (HNSCC) and treatment response in patients receiving chemotherapy or combination of chemo- and radiotherapy. Cases with the PM genotypes of CYP2D6 di...
A case-control study consisting of 300 patients and an equal number of healthy controls was carried out to investigate the association of polymorphism in cytochrome P450 2C19 (CYP2C19), which results in poor and extensive metabolizers (PMs and EMs) genotypes, with squamous cell carcinoma of head and neck (HNSCC) and treatment response in patients r...