Sunil Kumar KN

Sunil Kumar KN
Central Council for Research in Siddha · Siddha Central Research Institute

PhD

About

199
Publications
163,098
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516
Citations
Introduction
Researcher with interdisciplinary knowledge and experience in Medicinal plants, specialized in Pharmacognosy, experienced in Phytochemistry, interested in Pharmacology. Taxonomy is a passion, microscopy is the field of expertise. Working on medicinal plants identification in fresh as well as dry form using pharmacopoeial procedures. Exploring DNA fingerprinting methods to enrich quality control methods of herbal drugs for use in Pharmacopeias. 14 years of experience in herbal drug research.
Additional affiliations
October 2016 - present
Central Council for Research in Siddha
Position
  • Research Officer
June 2011 - October 2016
SDM Centre for Research in Ayurveda and Allied Science Udupi India
Position
  • Research Officer
June 2011 - present
SDM College of Ayurveda
Position
  • Lecturer
Description
  • Teaching Pharmacognosy, Phytochemistry, Quality control and Standardization of Ayurvedic drugs to MD (Ayu.) scholars - Dravyaguna and Agada tantra
Education
October 2007 - January 2014
Capt. Srinivasa Murthi Research Institute, The University of Madras
Field of study
  • Medicinal Plants - Pharmacognosy
June 2004 - May 2006
IPGT&RA, Gujarat Ayurved University
Field of study
  • Medicinal Plants - Pharmacognosy
June 2001 - May 2004
Shri Dharmasthala Manjunatheshwara College (Mangalore University), Ujire
Field of study
  • Pharmacognosy, Chemistry, Botany

Publications

Publications (199)
Article
Background Diabetes mellitus is a chronic metabolic disease that progresses to many microvascular complications. The phytoconstituents derived from herbs are thought to be important sources of anti-diabetic drug candidates. Mimosa pudica is one of such traditional herbal medicines having wide usage in treating diabetes mellitus. This study aims to...
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Introduction: Siddha being one of the ancient systems of medicine, has been counted on by most of the population during the outbreak of pandemics in recent times. The decoctions like nilavempu kutinir and kapacura kutinir have been authorized for prescription for conditions like dengue, Covid-19 etc. Kirampu kutinir (KK) is one such decoctions whic...
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Background: In Ayurveda, single or multiple herbs mixed in a particular proportion are used for the treatment of different diseases. Caturjata Curna (CC) is a popular Ayurvedic medicine with therapeutic application in tastelessness, diseases due to vitiated Kapha, poisoning and discoloration. The present study is an attempt to standardize a polyher...
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Classical Siddha medicine recommends the usage of functionally parallel substitute raw drugs in the scarcity of the original material. The concept of standard raw drug substitution is designated by the Tamil term Matru sarakku, which emphasizes selecting alternatives either in herbal or non-herbal sources based on certain attributes. Functionally...
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Introduction: Serankottai (Semecarpus anacardium L.) is a Schedule E (1) drug and is considered for treating all kinds of Vatha diseases, venereal disease, skin disease and cancerous conditions. Suthi murai denotes the purification process before any drug is employed in medicine. This study is aimed at evaluating the impact of Siddha purification...
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The present work aims to study powder microscopy, physicochemical and high-performance thin-layer chromatography photo documentation and fingerprint profiles of a Siddha drug, Rattha Piththathirku Kudinir Chooranam (RPK). The raw drugs were collected, authenticated and the RPK was prepared. Then the drug was investigated for powder microscopic char...
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Hemidesmus indicus (L.) R. Br. (Apocynaceae) root is extensively used in Indian traditional systems due to its biological activities. Decalepis hemiltonii Wight & Arn. is another member from the same family resembling H. indicus and is adulterated in the herbal market. Aim of the study was to compare and evaluate the distinguishing features based o...
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Medicinal plants have different types of active phytochemicals, which are still in use, either in their crude form or after proper processing. Though most of the plant drugs are safe, few are poisonous and may cause immediate toxic effect or cumulative toxic effect for human health. There are 25 poisonous or toxic plants in Siddha texts listed in t...
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RAPD analysis was carried out to determine genetic diversity that occurred among the selected accessions of H. elasticus obtained from six different hosts. All together 10 random primers were used for the RAPD assay, of which primer S11 produced 12 amplified bands in which 10 are polymorphic. Primer S9 produced the least number of amplified fragmen...
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Context: In traditional medicine, Kesaraja (Ayurveda) or Manjal karisali (Siddha) is effective for jaundice. Aim: Three species of Asteraceae need to be studied for their therapeutic superiority of their intended claim. They are Wedelia chinensis (Osbeck) Merr. Philipp J., Wedelia trilobata (L.) Hitchc. and Eclipta prostrata (L.) L. (Asteraceae). T...
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Siddha system of medicine is a distinct therapeutic science with many single drugs and compound formulations used for treating a broad spectrum of ailments. Siddha categorizes the fever manifested by viral infestation into 64 types and it has developed medicines for each type. Kapacurak / Kabasurak Kutinir (KK) described in the Citta Vaittiyattirat...
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The genus Viscum (Viscaceae) comprise of several species of hemi-parasitic plants with medicinal properties. Commonly known as mistletoes, these plants grow on other trees with the partial parasitic association. Viscum angulatum B.Heyne ex DC. is one such less explored leafless mistletoe of Asian countries with medicinal claims. In Ayurveda (Bandak...
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Infertility is a major health concern that may be caused due to inadequate fertility hormones or poor quality of reproductive parameters. The environmental pollutants such as cadmium is one of the causative factors for inducing infertility in men. Cadmium accumulates in various tissues and affects reproductive organs, especially testis which is hig...
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Pteridophytes are gaining importance as therapeutic agents due to the presence of various phytochemicals and their promising bioactivities. Drynaria quercifolia (L.) J. Sm., a Polypodiaceae member is endowed with numerous medicinal properties and finds wide usage in ethno as well as traditional medicines. The rhizome of D. quercifolia (L.) J. Sm. w...
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Liver detoxifies majority of chemicals and plays an important role in the maintenance of homeostasis of the body. In the recent years due to overwhelming use of drugs and alcohol there is an increased inci�dence of liver toxicities. The tubers of Actinoscirpus grossus are used in liver disease as a liver tonic in folklore medicine; However, there i...
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Arthritis and other rheumatoid or non-rheumatoid joint inflammations are prevalent among people all around the world. The plant-derived drugs and other herbal therapeutic practices are widely used against these malfunctions. Helicanthes elasticus (Desv.) Danser, an endemic hemiparasite was found less exploited for these types of disorders and this...
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Loranthaceae family includes hemiparasitic members which are seen invading a wide range of commercial crops. Helicanthes elasticus (Desv.) Danser is very common on mango trees. Though parasitic in nature, this mistletoe is also medicinally important as fetoprotective, against vesicular calculi and kidney infections. This study is an attempt to docu...
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Justicia beddomei (Clarke) Bennet, a member of Acanthaceae, is endemic to the Southern Western Ghats. This plant shows remarkable similarities with J. adhatoda L., and the only morphological difference is the smaller size of both leaves and inflorescence. J. beddomei has an abundance of phytochemicals and widely used in traditional medicinal system...
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Helicanthes elasticus (Desv.) Danser is a common type of mistletoes of Indian origin. In Indian traditional and folklore medicines the plant is claimed to possess a range of medicinal values such as immunomod-ulator, anti-diabetic and anti-microbial properties. However, there is no experimental proof for its therapeutic claim. The aqueous and alcoh...
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Background: Cinnamomum verum (true cinnamon or Tejpatra) is a well‑known spice with immense medicinal properties. Its adulteration with leaf and bark of other species belonging to genus Cinnamomum is found to be a common practice in India. Aims: Cinnamomum sulphuratum is used as a substitute of C. verum owing to its apparent macroscopic similaritie...
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Boerhaavia diffusa L. has been used extensively in Siddha system of medicine and is often confusedwith Trianthema portulacastrum L. due to morphological similarities. This particular study compares,analyses and identifies the key distinguishing features of the two whole plant drugs based onpharmacognostical and phytochemical aspects. The samples we...
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Introduction: 1/4th of all plant species in the world are at risk of being endangered or going extinct. The IUCN Red List is a critical indicator of the health of the world's biodiversity. It provides information about range, population size, habitat and ecology, use or trade, threats, and conservation actions that will help inform necessary conser...
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Introduction: Hydro distillation in Siddha medicine is the technique of extracting valuable principles from a pre-processed raw drug through the traditional process of distillation under a controlled temperature setting. Thiribhaladi Dravagam (TD) is one of the polyherbal distillate formulation stated in the Tamil medical text specified for phlegma...
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Objectives: To study pharmacognostical, physico-chemical, high performance thin layer chromatography and anti-oxidant activity potential of a Siddha drug “Noccik Kudinir Chooranam” (NKC). Methods: The raw drugs were collected, authenticated and the Kudinir Chooranam was prepared.Then the drug was subjected to powder microscopic diagnosis, physicoch...
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Objectives: To evaluate quality standards and to screen antioxidant activity of Cuvacakutori Chooranam (CC) a poly herbomineral Siddha formulation. Methods: The drug was prepared with authenticated ingredients. Powder microscopic, phytochemical, physicochemical, HPTLC fingerprint profiling (n-hexane, successive chloroform, successive ethanol), tota...
Data
The table contains the list of medicinal plants of South India which are authenticated by various molecular techniques.
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Traditional medical systems are advancing to the level of modern medicines in treatment and preventive aspects. The increased trade in medicinal plants provides income source for herbalists while substitution of rare ingredients with cheaper and more readily available species is misleading the end users. The prime cause of the problems associated w...
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The identification of plants by conventional keys and description is complex and tedious, due to the use of specific botanical terms making it quite difficult for non-experts and novices. In automated plant identification, leaf-based recognition is more common and reliable as it is claimed to be easily accessible and abundant compared to other plan...
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Siddha system of medicine was practiced thousands of years back. According to Siddha maruthuvar almost all plants bear medicinal properties. The medicinal properties are due to the phytochemicals found in them. Due to abundant availability these plants were used without any particular standardization process and safety precautions in the past. Nowa...
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Murungai poo, the flowers of Moringa oleifera Lam. are highly used in various traditional medical systems. The flowers contain bioactive phytochemicals and possesses promising antibacterial, antifungal, anti-larval, antioxidant, anti-inflammatory and anticancer properties. The authenticated flowers of M. oleifera were subjected to detailed macro mi...
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Background: In Siddha System of Medicine, Meliaceae members such as Azadirachta indica A. Juss., Melia azedarach L., Aglaia odorata Lour. etc., have been used as an ingredient in several formulations owing to their high potential therapeutic values. In recent decades, another member of this family Swietenia macrophylla King (broad leaved mahogany)...
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Murungai poo, the flowers of Moringa oleifera Lam. are highly used in various traditional medical systems. The flowers contain bioactive phytochemicals and possesses promising antibacterial, antifungal, anti-larval, antioxidant, anti-inflammatory and anticancer properties. The authenticated flowers of M. oleifera were subjected to detailed macro mi...
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Full-text available
Background: In Siddha System of Medicine, Meliaceae members such as Azadirachta indica A. Juss., Melia azedarach L., Aglaia odorata Lour. etc., have been used as an ingredient in several formulations owing to their high potential therapeutic values. In recent decades, another member of this family Swietenia macrophylla King (broad leaved mahogany)...
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Inflammatory bowel disease is an idiopathic, immune mediated and chronic inflammatory condition of intestine. The objective of the present study was to elucidate the protective effect of aqueous extract of fruits of Garcinia pedunculate (AEGP) in acetic acid induced ulcerative colitis in Swiss albino mice. The mice were grouped into four different...
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Background: Adulteration and substitution of Nagakesara is a well-established fact in the medicinal plant literature though it is referred by the authors of important Ayurvedic texts to cure piles, dysentery, hiccup etc.The botanical identities of controversial sources of Nagakesara are flowers of Mesua ferrea L. and Ochrocarpus longifolius Benth....
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ABSTRACT Ruta graveolens is known as common rue, belongs to family Rutaceae. Rue oil is obtained from steam distillation of fresh plant material and used as anthelminthic, antispasmodic, antiepileptic, rubefacient and emmenagogue. It’s a potential drug used in all the traditional systems of medicine. Aruvatha mattirai and Aruvathac curanam are the...
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Introduction: Dried flowers of Punica granatum L. constitute the drug Matulam poo which is widely used in both traditional and modern medicine. In Siddha it is used for the treatment of diabetes and gastro intestinal diseases. The present study deals with detailed pharmacognosy including morphological, anatomical, quantitative and powder microscopi...
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Introduction: Siddha system which aims at both curative and preventive aspects is a holistic treatment methodology using herbals, metals, minerals and animal products. Medicinal plant conservation is one of global concerns because the consequence is loss of many species useful in the primary healthcare of mankind. These natural resources are dwindl...
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Siddha system of therapeutic medicine is largely practiced in the South India. Root barks possess wide chemical compounds which has immense biological activity and medicinal values. Macro-microscopic detailing of three important root bark drugs in Siddha, Alangium salviifolium (L.f.) Wangerin (Azinjil verpattai) Senna auriculata (L.) Roxb. (Aavaram...
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Highlights The current study aims at exploring the bioactive molecules in Siddha Polyherbal Nilavembu Kudineer alleviating symptoms of Dengue/ Chikugunya. Editor’s Summary Nilavembu Kudineer is one of the thirty-two types of internal medicines described in the ancient Siddha system of medicine in south India which reduces fever and relieves body...
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Background: Medicinal plants are playing very active role in traditional medicines for the treatment of various ailments. Thiripala chooranam tablet, a polyherbal Siddha formulation is used for treating gastric ulcer, skin disease, constipation, piles, wounds, gum bleeding, liver diseases etc. Therapeutic efficacy of many Siddha formulations depend...
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Background: Dioscoria species is a Kanda Shakha (tuberous vegetable) useful as vegetable and grows abundantly around Udupi district, Karnataka, India. Dioscorea esculenta Burkill is one of the rare and costly tuber cultivated in very few areas of Udupi. Colloquially known as Duk-Genasu and Tuppa-Genasu the boiled tuber is used as a nutritional supp...
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About: Panchavalkala is a combination of five bark drugs indicated in wide range of therapeutics in Ayurveda. These are the barks of five trees ie. Nyagrodha (Ficus benghalensis L.), Udumbara (Ficus racemosa L.), Ashwatha (Ficus religiosa L.), Plaksha (Ficus lacor Buch. Ham.), Parisha (Thespesia populnea (L.) Sol.ex Correa). Barks of these trees ar...
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Introduction: Urolithiasis is a complex process that occurs from series of several physicochemical event including super-saturation, nucleation, growth, aggregation and retention within the kidneys. Data from in-vitro, in-vivo and clinical trials reveal that phytotherapeutic agents could be useful as either alternative or an adjunct therapy in the...