Sundareswaran Loganathan

All India Institute of Medical Sciences Guwahati · Physiology

The Intergovernmental Panel on Climate Change, IPCC predicts that hot seasons will get even hotter due to global climate change. There exists a critical dependence of human metabolic processes on temperature. Changes in thermal balance therefore, have an adverse effect on health because they raise body temperature, cause excessive sweating, and acc...

The concept of serious games and gamification in medical education is gaining attention due to its nature of curiosity and to engage the student's attention by simultaneous cultivation of their higher-level thinking without the experience of boredom. Significant differences were reported among the present medical students, generations Y and Z compa...

Background & Objective: Oral examinations or viva is a common mode of assessment for medical students. It is not possible to cover the entire syllabus and students often feel that the “luck factor” plays a major role in deciding their performance. Efforts have been made to address these shortcomings associated with traditional viva exams, mainly by...

Objective The objective of our study was to assess the impact of heat stress on hydration and cognition among outdoor workers in hot environment. Methods Area heat stress assessments were measured using Quest Temp WBGT monitor. Sweat rate for dehydration and reaction time for acute cognitive processing were recorded using standard procedures. Res...

Serious games and gamification concept is gaining attention in medical education due to its ability to engage the student's attention by cultivation of their higher level thinking without the experience of boredom. Significant differences were noted among the learning styles of medical students Generation Y & Z compared to earlier generations. The...

Background: Various diagnostic tools are used to assess cutaneous psoriasis, but most of it were subjective. Sympathetic skin response (SSR), skin PH and temperature objectively measure the skin barrier functions that could aid clinicians to evaluate accurately and predict skin disease incidence even before the onset of clinical symptoms. Aim and...

Background: The stress levels among the 1st year MBBS students are high due to multiple factors. In this setting, an objective assessment of stress and coping strategies among medical students may provide a foundation to adopting specific measures to help them. Aims and Objectives: The specific objectives of the study were to compare stress levels...

Background Inappropriate sitting posture leads to musculoskeletal problems and is reported to be linked with the individual's confidence. This study explores the importance of recommended sitting posture on student, health, and sleep. Methods 70 volunteer adolescent students aged 18–26 years were enrolled in this study. Instructions and sensitizat...

Sedentary behaviour is hypothesized to be a potential target in its own right—the rising numbers of persons with cognitive impairment highlight the urgency to understand these risk factors better. Higher sedentary behaviour levels are associated with reduced global cognitive functioning and slower cognitive decline, especially in older persons. Neu...

Diabetes Mellitus is a very common disease prevalent all across the world including the Indian subcontinent. With over 69 million people with Type 2 DM, India has the second highest number of people living with diabetes mellitus worldwide. Considering the current scenario, understanding newer aspects of the pathophysiology of Diabetes Mellitus is o...

Background Globally, the current medical emergency for novel coronavirus 2019 (COVID-19) leads to respiratory distress syndrome and death. Purpose This review highlighted the effect of COVID-19 on systemic multiple organ failure syndromes. This review is intended to fill a gap in information about human physiological response to COVID-19 infection...

Background Sheetali pranayama is a cooling pranayama practiced for hypertension (HTN). The effects of Sheetali pranayama, as a solitary intervention on cardiovascular and autonomic changes in hypertension is unknown. Materials and methods The current study was conducted on 100 patients with HTN, randomly allocated to HTN with pranayama (Interventi...

Abstract Background Managing the condition of corticosteroid resistant asthmatic patients is quite difficult and challenging despite the advent of modern medications. Hot Foot and arm bath (HFAB) is a widely used treatment modality for the management of bronchial asthma in Naturopathy. However, no scientific documentation or study is available so f...

Abstract: Numerous studies have illustrated the impact of stress on addiction, its development, relapse vulnerability, and the dopamine mechanism. However, various studies on noise exposures as a stressor had been done, which could alter the hypothalamic–pituitary–adrenal (HPA) axis. Noise exposure harmful effect and changes in the individual’s hea...

Background: In neuropsychological assessment, the time taken by a subject or patient to respond to stimulus provides valuable information about processing in central and peripheral nervous system. Reaction time is a simple and inexpensive method commonly used in cognitive and sport physiology to assess the sensory-motor performance of an individual...

Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairment in social interactions, communication, restricted, and repetitive behaviors. Evidence‑based treatment options for ASD are limited. Yoga is practiced by over 20 million people worldwide, and multiple studies have investigated yoga as a possible ef...

Noise has detrimental effect on health. The negative consequences on health may differ according to the individual intensity and perception. Environmental influence on the inflammatory as well as immune pathways is associated with chronic inflammation, tissue damage and finally leads to disease. The aim of this study to investigate the noise exposu...

This study assesses the effect of long-term intake of aspartame on liver function and apoptosis signaling pathway in the Wistar albino rats. Several reports have suggested that methanol is one of the major metabolites of Aspartame. Non-primate animals are usually resistant to methanol-induced metabolic acidosis due to high levels of hepatic folate...

There is ample evidence stating Polychlorinated biphenyls (PCBs) as neurotoxins. In the current study, we have analyzed the behavioural impact of PCBs exposure in adult rats and assessed the simultaneous effect of antioxidant melatonin against the PCBs action. The rats were grouped into four and treated intraperitoneally with vehicle, PCBs, PCBs +...

Background: Noise acts as a stressor and is reported to have impact on individual health depending on nature, type, intensity and perception. Modern medicine has no effective drugs or cure to prevent its consequences. Being an environmental stressor noise cannot be avoided; instead minimizing its exposure or consuming anti-stressor and adaptogens f...

Background/Objectives: The present study was done to explain the importance of physical activity (PA) on autonomic nervous system. We have compared the short-term heart rate variability (HRV) between football players and normal controls lacking PA, fitness, and exercise. Design: Case–control study. Methods: The sample included 40 football players a...

Background: The objective of this study is to evaluate the immunization and stress dormant role in humoral and cell mediated response after sub-acute exposure of noise stress and immunomodulatory activity of Indigofera tinctoria (I. tinctoria). Method: Noise stress was done by broadband white noise generator (0–26 kHz), 100 dB, 4 h daily for 15 day...

Background: Heart rate variability (HRV) analysis is a simple and noninvasive technique capable of assessing autonomic nervous system modulation on heart rate (HR) in healthy as well as disease conditions. The aim of the present study was to compare (validate) the HRV using a temporal series of electrocardiograms (ECG) obtained by simple analog amp...

Background: Noise stress has different effects on memory and novelty and the link between them with an electroencephalogram (EEG) has not yet been reported. Objective: To find the effect of sub-acute noise stress on the memory and novelty along with EEG and neurotransmitter changes. Materials and methods: Eight-arm maze (EAM) and Y-maze to ana...

Aspartame (non-nutritive sweetener) is consumed by millions of people in products like beverages, instant breakfasts, desserts, breathe mints, sugar free chewing gum, vitamins, and pharmaceutical. On a weight basis, metabolism of aspartame generates approximately 50% phenylalanine, 40% aspartic acid and 10% methanol. The detailed mechanisms of thei...

Aspartame is a non-nutritive sweetener that is used predominantly in various ‘diet’ and ‘low-calorie’ products, such as beverages, instant breakfasts, desserts, breath mints, sugar-free chewing gum, vitamins, and pharmaceuticals, consumed by millions of people who are attempting weight loss, young adults and diabetic persons. On a weight basis, the...

The objective of this study is to find out 1) sub-acute noise stress effects on neutrophil functions and 2) to examine the effect of Scoparia dulcis as an immunomodulatory and anti-stressor agent. Four groups of rats were used control, control fed with Scoparia, noise-stress exposed, noise-stress exposed fed with Scoparia. Blood was used for the as...

The aim of the study is to elucidate the effect of acute noise stress on memory and novelty. Rats were exposed to acute noise/4 hr/day and analyzed for memory and novelty. The results were noted after noise exposure at the interval of 1 hr, 4 hr and post day and shows a significant alterations in working and reference memory, time to complete in ra...

Aspartame is most commonly found in low calorie beverages, desserts and table top sweeteners added to tea or coffee. It is widely consumed by humans who are diabetic and who are under weight loss regime. Aspartame is rapidly and completely metabolized in humans and experimental animals to aspartic acid (40%), phenylalanine (50%) and methanol (10%)....

Ever increasing reasons that generate more endangered species depends on various factors and also depends on the species involved. The causes for declining amphibian population declines are complex. Amphibians are playing key roles in the structure and function of natural habitats and also act as bio indicators of environmental change and may be de...