About
17
Publications
5,357
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
140
Citations
Introduction
Suman Panda currently works as a Post-Doctoral Scientist at the Department of Optics and Bioscience, Ecole Polytechnique (X), Institut Polytechnique de Paris, France. Suman does research in the area of Biophysics, Anti-Viral Molecules and Cancer Drug designing.
Current institution
Additional affiliations
September 2024 - present
Ecole Polytechnique | Institut Polytechnique de Paris | CNRS | INSERM | France
Position
- Post Doctoral Scientist
Description
- Suman Panda currently works at the LOB, Ecole Polytechnique, Institut Polytechnique de Paris. Suman does research in the area of Biophysics ,Medicinal Chemistry, and Drug designing.
July 2016 - June 2018
September 2015 - August 2016
Raja Peary Mohan College
Position
- Guest Faculty
Education
August 2012 - July 2014
Publications
Publications (17)
Summarising the study, RSV is an important pathogen that causes oncogenic transformation in its host via the action of a protein kinase that it expresses. The RSV genome is reverse‐transcribed into its complementary DNA, which then integrates into the host genome. This DNA thereafter serves as a template for transcription to manufacture viral prote...
Vascular endothelial growth factor-A (VEGF-A) is a growth factor and pluripotent cytokine that promotes angiogenesis in cancer cells, transitioning to an angiogenic phenotype. The binding of VEGF-A protein to VEGF receptors (VEGFR-1 and VEGFR-2) initiates a cascade of events that stimulates angiogenesis by facilitating the migration and enhancing t...
The Rous sarcoma virus (RSV) is an onco-retrovirus that infects avian species such as the chicken (Gallus gallus). RSV is the first oncovirus to be described and the oncogenic activity of this virus is related to the expression of a tyrosine kinase that induces carcinogenic transformation. Interestingly, we have noted that the RSV genome contains v...
ORAI1 is an intrinsic component of store-operated calcium entry (SOCE) that strictly regulates Ca2+ influx in
most non-excitable cells. ORAI1 is overexpressed in a wide variety of cancers, and its signal transduction has
been associated with chemotherapy resistance. There is extensive proteomic interaction of ORAI1 with other
channels and effect...
ORAI1 is an intrinsic component of store-operated calcium entry (SOCE) that strictly regulates Ca 2+ influx in most non-excitable cells. ORAI1 has been extensively studied to have been overexpressed in various cancer phenotypes, and its signal transduction has been associated with oncotherapy resistance. There is extensive proteomic interaction of...
Vascular Endothelial Growth Factor A (VEGF A), a pluripotent cytokine and angiogenic growth factor mediates the switch to an angiogenic phenotype in cancer cells. The interaction of VEGF A protein with the VEGF receptors (VEGFR 1and VEGFR 2) starts downstream effect that promotes angiogenesis by mediating migration and increasing the permeability o...
Most of the human cancers are dependent on telomerase to extend the telomeres. But ∼10% of all cancers use a telomerase-independent, homologous recombination mediated pathway called alternative lengthening of telomeres (ALT). Due to poor prognosis, the ALT status is not being considered yet in the diagnosis of cancer. No such specific treatment is...
Last few decades unveiled the existence of diverse pool of non-coding RNAs, small RNAs, and repetitive elements which can play a pivotal role in maintaining the cellular homeostasis and dysfunction. Time- and tissue-dependent gene regulation by these small RNAs in-vivo made them a new class of pharmacological agents. The therapeutic effects of conv...
Reactive oxygen and nitrogen species (RONS) can be produced in our system by several endogenous and exogenous processes, leading toward the accumulation of oxidative lesions throughout the genome. Oxidative DNA damage is a major threat to genomic integrity, thus resulting in the manifestation of various chronic diseases including cancer, cardiovasc...
Background
Antibiotic resistances of pathogens and breast cancer warrant the search for new alternative strategies. Phytoextracts can eradicate microbe-borne diseases as well as cancer with lower side effects compared to conventional antibiotics.
Aim
Unripe and ripe Azadirachta indica (neem) seed extracts were explored as potential antibiofilm and...
G-Quadruplex (GQ) nucleic acids are promising therapeutic targets in anticancer research due to their structural robustness, polymorphism, and gene-regulatory functions. Here, we presented the structure−activity relationship of carbazole-based monocyanine ligands using region-specific functionalization with benzothiazole (TCA and TCZ), lepidine (LC...
G-Quadruplex (GQ) nucleic acids are promising therapeutic targets in anticancer research due to their structural robustness, polymorphism, and gene-regulatory functions. Here, we presented the structure–activity relationship of carbazole-based monocyanine ligands using region-specific functionalization with benzothiazole (TCA and TCZ), lepidine (LC...
The drug resistance of cancer cells is a major concern in medical oncology, resulting in the failure of chemotherapy. Ca²⁺ plays a pivotal role in inducing multidrug resistance in cancer cells. Calcium signaling is a critical regulator of many cancer hallmarks, such as angiogenesis, invasiveness, and migration. In this review, we describe the invol...
G-quadruplex, a unique secondary structure in nucleic acids found throughout human genome, elicited widespread interest in the field of therapeutic research. Being present in key regulatory regions of oncogenes, RNAs and telomere, G-quadruplex structure regulates transcription, translation, splicing etc. Changes in its structure and stability leads...
Solute carrier proteins (SLCs), the most understudied and second largest group of membrane proteins, maintain cellular metabolic homeostasis via the export and import of various solute, ions, metabolites, and even drugs. Given the importance of SLCs in maintaining normal cellular function, dysregulation of these proteins leads to the dramatic progr...
G-quadruplex, a unique secondary structure in nucleic acids found throughout human genome elicited widespread interest in the field of therapeutic research. Being present in key regulatory regions of oncogenes, G-quadruplex structure regulates transcription, translation, splicing, telomere stability etc. Changes in its structure and stability lead...
