Sukho Park

Sukho Park
Daegu Gyeongbuk Institute of Science and Technology | DGIST · Department of Robotics Engineering

Ph. D

About

732
Publications
82,234
Reads
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14,117
Citations
Additional affiliations
January 2009 - June 2015
Chonnam National University
Position
  • Professor (Associate)

Publications

Publications (732)
Article
Full-text available
Precise sensing of pressure is essential for various mechanical and electrical systems. The recent emergence of flexible pressure sensors has enabled novel applications, such as human–machine interfaces, soft robotics, and wearable devices. Specifically, the piezoresistive sensing scheme is widely adapted for flexible pressure sensors as it is simp...
Article
In this study, for intention recognition, a convolutional neural network (CNN) classification model using the electromyography (EMG) signals acquired from the subject was developed. And, for sensory feedback, a rule-based wearable proprioceptive feedback haptic device, a new method for providing feedback on the grip information of a robotic prosthe...
Article
Full-text available
Drug‐Loaded Mucoadhesive Patch In article number 2100203, Sukho Park and co‐workers demostrate a drug‐loaded patch equipped in wireless capsule, which is delivered to the gastrointestinal tract rapidly and accurately by an external magnetic field. The patch has excellent mucoadhesive properties even in a wet gastrointestinal environment. Since magn...
Article
Flexible electronic devices with flexible sensors have drawn enormous attention due to their wide variety of applications, such as wearable health monitoring devices, bendable touch screens, flexible storage devices, artificial skins, etc. However, the mechanical and electrical performance of devices should be enhanced by new materials design or an...
Article
Full-text available
Herein, a mucoadhesive patch for gastrointestinal tracts with active delivery, hyperthermia, and controlled drug release function using a magnetically actuated capsule is proposed to overcome the drug delivery and efficiency challenges of wireless structures. The proposed patch has excellent adhesion to the gastrointestinal tract and contains antic...
Article
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The attention in lab-on-a-chip devices with their potent application in medical engineering has prolonged swiftly over the last ten years. Travelling through the technology development, innovative microfluidics devices shown enormous potential to lift the lab-on-a-chip biomedical research in traditions that are not imaginable using conventional tec...
Cover Page
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The ZIF-67 based additively manufactured triboelectric nanogenerator to shed light upon the room temperature solvent assisted synthesis, physiochemical properties and self-powered robot object detection.
Article
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The ionic polymer transducers (IPT) have been widely proposed for actuators, energy harvesting, pressure sensing, and robotics applications owing to their exceptional flexibility and actuation performance. However, IPT sensors have a limitation of low output voltage (<1 V) with bending strain that hampers their application in energy harvesting devi...
Article
Harvesting mechanical energy from surroundings can be a promising power source for micro/nano-devices. The triboelectric nanogenerator (TENG) works in the principle of triboelectrification and electrostatic induction. So far, the metals and polymers mostly dominate the conventional triboelectric series, but there is a need to find novel materials t...
Article
High-performance foldable metal-coated ionic polymer-metal nanocomposites (IPMNCs) with crack minimized electrode are desired for wearable electronics, energy harvesting devices, tactile sensors, structural health monitors, humidity sensors, and supercapacitor devices. However, the IPMNC shows the cracked structure that seriously decreases the perf...
Article
Recently, natural exosomes have attracted attention as an ideal drug carrier to overcome the limitations of existing drug delivery systems which are toxicity induction and low cancer-targeting performance. In this study, we propose an exosome-based hybrid nanostructure (EHN) with improved targeting ability and therapeutic efficacy against colorecta...
Article
Therapeutic drug delivery microrobots capable of accurate targeting using an electromagnetic actuation (EMA) system are being developed. However, these drug delivery microrobots include a large number of magnetic nanoparticles (MNPs) for accurate EMA targeting, which causes side effects, such as problems with membrane integrity and normal cell apop...
Article
Full-text available
In this paper, we propose the active delivery of multi-layer drug-loaded microneedle (MN) patches using a capsule that can be driven by an external magnetic field. Firstly, the multi-layer drug-loaded MN patches consist of three delivered MN patches which are composed of a drug-loaded MN patch and polydimethylsiloxane layer. The drug-loaded MN patc...
Article
In article 2000118, Sukho Park and co‐workers propose a bilayer hydrogel sheet‐type intraocular microrobot consisting of a therapeutic layer and an magnetic nanoparticles (MNPs) layer. The bilayer hydrogel microrobot capable of locomotion using a magnetic field can accurately move to a target lesion, dissolve the therapeutic layer by alternatingmag...
Article
In order to overcome the limitations of the A* algorithm in the autonomous control of electromagnetically actuated microrobots, this study introduces three modified path planning algorithms (A*-WAPP, A*-waypoints, A*-WAPP-waypoints) using the concept of Wall Avoiding Path Planning (WAPP) and waypoints. Through the autonomous driving experiment of a...
Article
Magnetic drug targeting (MDT) is a therapeutic method that delivers drug carriers containing magnetic nanoparticles to a target lesion by directing them using an external magnetic field. To minimize the possible side effects on the surrounding normal cells, focused magnetic drug targeting (FMDT) has been introduced, which allows drug carriers to be...
Article
By virtue of minimum invasiveness and driving ability using a magnetic field, drug delivery with the aid of a microrobot has an inherent potential for targeted treatment for the eye. The use of microrobots, however, has the limitation of leaving magnetic nanoparticles (MNPs) in the eye that can cause side effects. In this study, a bilayer hydrogel...
Article
Twisted string actuators (TSAs) have been used where conversion of the rotational motion of a motor into a translatory motion by twisting two strings to control the length of the actuator is needed, e.g., in robot applications. Speed mode TSA (SM-TSA) improves the translatory motion achieved in previous TSAs by adding a shaft between two strings. H...
Article
Recently, significant attention has been paid to the development of electromagnetically actuated microrobots. Various types of electromagnetic actuation (EMA) systems have been proposed and put into practice. Owing to their limited workspace and driving force, the previous EMA systems were used restrictively in microrobots of specific sizes. Arguab...
Article
For manipulators used in minimally invasive surgery (MIS), variable stiffness and miniaturization are very important characteristics. However, previously proposed mechanisms are difficult to miniaturize due to large and complex structures; thus, they do not achieve variable stiffness characteristics, consequently being difficult to be applied to ma...
Article
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Until now, magnetic hyperthermia is applied to remove solid tumors by targeting magnetic nanoparticles (MNPs) to tumor sites. In this study, leukemia cells in the bloodstream were directly removed under whole-body hyperthermia, using leukemia cell-specific MNPs. Epithelial cellular adhesion molecule (EpCAM) antibody was immobilized on the surface o...
Article
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Graphene quantum dots (GQDs)-decorated hollow copper sulfide nanoparticles (CuS NPs) were developed as a multifunctional platform for controlled intracellular drug release and enhanced photothermal-chemotherapy. The CuS NPs were firstly synthesized to encapsulate anticancer drug doxorubicin (DOX) followed by the GQDs decoration on the surface of Cu...
Article
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Nanorobots are safe and exhibit powerful functionalities including delivery, therapy, and diagnosis. Therefore, they are in high demand for the development of new cancer therapies. Although many studies have contributed to the progressive development of the nanorobot system for anticancer drug delivery, these systems still face some critical limita...
Article
A twisted string actuator (TSA) is an effective method that can change the rotational motion of a motor into a linear motion, as well as control the speed and stiffness of the actuator. In particular, because the speed mode of the TSA (SM-TSA) can adjust the rotation–linear motion ratio by changing the diameter and length of the twisting shaft, it...
Article
Drug therapy using cancer-targeted drug delivery particles is widely adopted as a general anti-cancer therapy. In this approach, anticancer drug particles target mainly cancer cells, thereby reducing the side effects caused by anticancer drug particles against normal cells. However, these cancer-targeted drug delivery particles still have many risk...
Article
This paper introduces electromagnetically actuated biomedical microrobots using external stimulus responsive hydrogels. We briefly summarize several research trends using representative magnetic actuated hydrogel microrobots developed to date and introduce our three developed types of magnetic actuated hydrogel microrobots. First, we propose a sele...
Article
Full-text available
Currently, microrobots are receiving attention because of their small size and motility, which can be applied to minimal invasive therapy. Additionally, various microrobots using hydrogel with the characteristics of biocompatibility and biodegradability are also being developed. Among them, microrobots that swell and deswell in response to temperat...
Article
Purpose As a promising intravascular therapeutic approach for autonomous catheterization, especially for thrombosis treatment, a microrobot or robotic catheter driven by an external electromagnetic actuation system has been recently investigated. However, the three-dimensional (3D) real-time position and orientation tracking of the microrobot remai...
Article
This work proposes the targeted transport of therapeutic agents using a thermo-electromagnetically actuated microrobot. This microrobot is fabricated via UV polymerization using 2D lithography and is composed of an electromagnetically actuated layer (polyethyleneglycol diacrylate dispersed with iron(II,III) oxide and a thermo-responsive layer (N-is...
Article
Full-text available
Despite advancements in treating ruptured cerebral aneurysms, an aneurysmal subarachnoid hemorrhage (aSAH) is still a grave cerebrovascular disease associated with a high rate of morbidity and mortality. Based on the literature published to date, worldwide academic and governmental committees have developed clinical practice guidelines (CPGs) to pr...
Article
Multifunctional polymeric micelles were developed as a promising dual tumor-targeted drug delivery platform for magnetic resonance (MR) imaging and combined photothermal-chemotherapy. HA-C16 copolymers were synthesized via peptide formation process with subsequent co-encapsulation of therapeutic agent docetaxel (DTX) and superparamagnetic iron oxid...
Chapter
This chapter introduces tumor-targeting bacteriobots. In the first part, the fabrication of microstructures as a theragnostic part of the bacteriobot using biocompatible materials, such as poly lactic-co-glycolic acid (PLGA), and poly ethylene glycol (PEG), is explained. Then, the motility control of bacteriobots is explained. At the end of the cha...
Article
We propose the use of folate-receptor-targeted, near-infrared-sensitive polydopamine nanoparticles (NPs) for chemo-photothermal cancer therapy as an enhanced type of drug-delivery system which can be synthesized by in situ polymerization and conjugation with folic acid. The NPs consist of a Fe3O4/Au core, coated polydopamine, conjugated folic acid,...
Article
During algal bloom periods, operation of seawater reverse osmosis (SWRO) pretreatment processes (e.g. ultrafiltration (UF)) has been hindered due to the high concentration of algal cells and algal organic matter (AOM). The present study evaluated for the first time the performance of titanium salts (i.e. titanium tetrachloride (TiCl4) and polytitan...
Article
A cable-driven parallel robot (CDPR) is a robot in which rigid links are replaced with cables, unlike conventional serial or parallel robots. The main advantages of a CDPR are a relatively large workspace, high payload capacity, and high speed. Given the advantages of CDPR, it has recently been widely studied in the field of monitoring, constructio...
Chapter
In this paper, we present two preliminary experiments, under laboratory environment, in order to determine whether or not our robotic bed needs a deflection correction function due to patient’s various weights and its postures. We measured (1) robotic arm’s deflection with various loads from 0 to 80 kg, and (2) variation of carbon bed’s deflection...
Article
Autologous cell-based therapy using scaffold has attracted great interests in articular cartilage regeneration. In article number 1601378, a magnetically actuated microscaffold with the capability of targeted mesenchymal stem cell delivery for articular cartilage regeneration is described by Sukho Park and co-workers. They show that the porous micr...
Article
Patient-friendly capsule endoscopes with a high-definition camera have gradually become a popular solution to the diagnosis of digestive systems. As a promising method for an active and precise diagnosis, an active locomotive intestinal capsule endoscope (ALICE) with wireless functionality using an electromagnetic actuation (EMA) system has been pr...
Article
Recently, many researchers have focused on wireless microrobots as therapeutic agents for active drug delivery. Owing to their size limitation, they cannot be equipped with actuators/sensors, controllers and batteries. Therefore, external devices (magnetic field generator, position recognition devices, and control system) are used to realize the ma...
Article
This study proposes a magnetically actuated microscaffold with the capability of targeted mesenchymal stem cell (MSC) delivery for articular cartilage regeneration. The microscaffold, as a 3D porous microbead, is divided into body and surface portions according to its materials and fabrication methods. The microscaffold body, which consists of poly...
Article
Human-friendly electronic products, such as smart mobile phones, soft haptic devices, wearable electronics, and implantable or disposal biomedical devices, will require the use of high-performance durable soft electroactive actuators with eco-friendly, biocompatible, and biodegradable functionalities. Here, we report a high-fidelity bioelectronic m...
Article
The aim of this work is to prepare and evaluate a novel lipid-polymer hybrid liposomal nanoplatform (hyaluronic acid-magnetic nanoparticle-liposomes, HA-MNP-LPs) as a vehicle for targeted delivery and triggered release of an anticancer drug (docetaxel, DTX) in human breast cancer cells. We first synthesize an amphiphilic hyaluronic acid hexadecylam...
Article
Background: Reactivation of hepatitis B virus (HBV) is one of the most important side effects in IBD patients with HBV infection treated with anti-TNF-alpha agents. We investigated the rate of prophylaxis and the risk of HBV reactivation in HBV infected patients with IBD receiving anti-TNF-alpha therapy. Methods: This was a retrospective multicente...
Article
Background: Although the use of anti-TNFs or immunomodulators (IMs) in the early course of disease is believed to be effective in improving long-term outcomes of patients with Crohn's disease (CD), especially those with poor prognostic factors, this concept was not clearly proved in Asian patients. Methods: We retrospectively analyzed clinical data...
Article
Background: The aim of this study was to evaluate the diagnostic role of fecal calprotectin (FC) as a noninvasive marker for the disease activity of ulcerative colitis (UC) in the Korean cohort. Methods: A total of 168 fecal samples were collected from 168 UC patients (April 2015-September 2016). FC was measured using the Quantum Blue® Calprotectin...
Article
Background: Large scaled-studies regarding long-term outcomes of adalimumab (ADA) treatment in Korean patients with Crohn's disease (CD) are still lacking. Methods: We retrospectively analyzed long-term outcomes of ADA treatment in Korean CD patients who started to be given scheduled ADA treatments at Asan Medical Center between November 2008 and J...
Article
The fabrication of strong conducting composite sheets (CCSs) using a simple technique with cost-effective materials is desirable for capacitor, decoupling capacitor, and electromagnetic interference (EMI) shielding applications. Here, we used cost-effective graphite flakes (GFs) as a conducting filler and amorphous poly (styrene-co-acrylonitrile) (...
Article
In this paper, we proposed a magnetically steerable guidewire device composed of two parts: steering part and feeding part. The steering part consists of a magnet attached to the end of a commercial guidewire and 2-pair Helmholtz coils, and the feeding part consists of a motorized stage and a device for holding the guidewire. In detail, the 2-pair...
Article
This article presents a haptic-guided teleoperation for a tumor removal surgical robotic system, so-called a SIROMAN system. The system was developed in our previous work to make it possible to access tumor tissue, even those that seat deeply inside the brain, and to remove the tissue with full maneuverability. For a safe and accurate operation to...
Article
Full-text available
Patients with severe stroke due to acute large cerebral artery occlusion are likely to be severely disabled or die if reperfusion is not achieved in a timely manner. Intravenous tissue plasminogen activator (IV-TPA) administered within 4.5 hours after stroke onset was previously the only proven therapy, but IV-TPA alone does not sufficiently improv...
Article
Seasonal green algae blooms in freshwaters have raised attention on the need to develop novel effective treatment processes for the removal of algae in water. In the present study, the performance of newly developed polytitanium tetrachloride (PTC) coagulant for the removal of freshwater microalga Chlorella vulgaris has been investigated and compar...
Article
Full-text available
Background and Purpose There is conflicting evidence for whether or not the incidence of stroke is influenced by the daily temperature. The association between daily temperature and incidence of stroke is largely unknown in Korea. This study attempted to evaluate whether the maximum or minimum daily temperature is associated with increased numbers...
Article
This paper describes a robotic patient positioning system (PPS) for a fixed-beam heavy-ion therapy system. In order to extend the limited irradiation angle range of the fixed beam, we developed a 6-degree-of-freedom (6-DOF) serial-link robotic arm and used it as the robotic PPS for the fixed-beam heavy-ion therapy system. This research aims to deve...
Article
Most robotic colonoscopes do not allow sufficient space for high capacity motors since their power sources are equipped in their bodies. Therefore, a robotic colonoscope activated by an external motor through a flexible shaft has been presented. Unfortunately, robot rotations resulting from excessive input torque are observed under some input volta...
Article
We fabricated a pore size–controlled porous Nafion membrane using a silica sol–gel process and hydrofluoric acid etching and we developed an enhanced ionic polymer–metal composite actuator using the porous Nafion membrane through the electroless plating and ion exchange procedure. As the pore size of the proposed porous Nafion membrane decreased, t...