Suellen Almeida-Corrêa

Suellen Almeida-Corrêa
Weizmann Institute of Science | weizmann · Department of Neurobiology

PhD

About

9
Publications
1,325
Reads
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109
Citations
Additional affiliations
December 2018 - present
Weizmann Institute of Science
Position
  • PostDoc Position
February 2014 - November 2018
Max Planck Institute of Psychiatry
Position
  • PhD Student
August 2011 - September 2013
Federal University of Rio de Janeiro
Position
  • Master's Student

Publications

Publications (9)
Article
Full-text available
Manganese-enhanced magnetic resonance imaging (MEMRI) is a powerful tool for in vivo non-invasive whole-brain mapping of neuronal activity. Mn2+ enters active neurons via voltage-gated calcium channels and increases local contrast in T1-weighted images. Given the property of Mn2+ of axonal transport, this technique can also be used for tract tracin...
Article
Manganese-enhanced magnetic resonance imaging (MEMRI) exploits the biophysical similarity of Ca²⁺ and Mn²⁺ to map the brain's activity in vivo. However, to what extent different Ca²⁺ channels contribute to the enhanced signal that MEMRI provides and how Mn²⁺ dynamics influence Mn²⁺ brain accumulation after systemic administration of MnCl2 are not y...
Article
Full-text available
Memory extinction involves the formation of a new associative memory that inhibits a previously conditioned association. Nonetheless, it could also depend on weakening of the original memory trace if extinction is assumed to have multiple components. The phosphatase calcineurin (CaN) has been described as being involved in extinction but not in the...
Article
Reconsolidation and extinction are two processes occurring upon memory retrieval that have received great attention in memory research over the last decade, partly due to their purported potential in the treatment of anxiety disorders. Due to their opposite behavioral effects, the two phenomena have usually been considered as separate entities, wit...
Article
Full-text available
When 5-lipoxygenase (5-LO) is inhibited, roughly half of the CNS effect of the prototypic endocannabinoid anandamide (AEA) is lost. Therefore, we decided to investigate whether inhibiting this enzyme would influence physiological functions classically described as being under control of the endocannabinoid system. Although 5-LO inhibition by MK-886...
Article
Full-text available
Dementia is a devastating age-related disorder. Its therapy would largely benefit from the identification of susceptible subjects at early, prodromal stages of the disease. To search for such prognostic markers of cognitive impairment, we studied spatial navigation in male BALBc vs. B6N mice in combination with in vivo magnetic resonance spectrosco...
Article
Expression of the lacZ-sequence is a widely used reporter-tool to assess the transgenic and/or transfection efficacy of a target gene in mice. Once activated, lacZ is permanently expressed. However, protein accumulation is one of the hallmarks of neurodegenerative diseases. Furthermore, the protein product of the bacterial lacZ gene is ß-galactosid...

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