Süleyman Sayar

Objective: There are many instruments to measure disease activity in ulcerative colitis. While determining clinical activity according to these instruments, many clinical and laboratory parameters are needed to be followed. Determination of disease activity with non-invasive and objective inflammatory indicators may be a practical and objective wa...

Background/aims: Hepatitis B reactivation (HBVR) is an important risk of treatment with tumor necrosis factor inhibitors (anti-TNF). While antiviral prophylaxis is recommended before treatment in HBsAg-positive patients, there is no clear approach for the follow-up or prophylactic treatment of patients with past hepatitis B virus (HBV) infection....

Objective: An association of gastric cancer and precursor lesions with gastric xanthelasma has frequently been reported. However, the incidence of both gastric xanthelasma and gastric cancer precursor lesions increases with age. The aim of this study was to evaluate the frequency and characteristics of atrophic gastritis, intestinal metaplasia and...

Objective: The fibrosis stage during diagnosis and the response to ursodeoxycholic acid in the 1st year of treatment are considered to be prognostic indicators in primary biliary cholangitis (PBC). Determining these indicators with non-invasive models can enable the risk of liver failure to be monitored with continuous variables from the moment of...

Background: The aim of this study was to evaluate the prevalence of osteopenia and osteoporosis in adult patients with celiac disease (CD) at diagnosis and/or in the follow-up after a gluten-free diet (GFD). Methods: Adult patients diagnosed with CD were retrospectively screened through follow-up records and computer databases. Patients assessed...

A 56-year-old male patient with a history of total colectomy and ileoanal pouch anastomosis for ulcerative colitis 20 years prior was hospitalized with intestinal obstruction, high C-reactive protein (CRP) level, and hypoalbuminemia. Magnetic resonance enterography (MRE) revealed 3 ileal short-segment inflammatory stenoses close to the pouch inlet....

Objectives Management of malignant gastrointestinal (GI) obstruction presents a significant challenge. Most patients are in a profoundly decompensated state due to underlying malignancy and are not ideal candidates for invasive surgical procedures. Self-expandable metallic stents (SEMSs) are used to provide permanent or temporary patency in all end...

Background/aim: Post-ERCP pancreatitis (PEP), post-sphincterotomy bleeding (PSB), and Post-ERCP perforation are the most common complications of endoscopic retrograde cholangiopancreatography (ERCP). Identification of risk factors for post-ERCP complications is critical for postoperative follow-up. This study aimed to evaluate the most common post...

Background and Aim: Portal vein thrombosis (PVT) is particularly detected in advanced liver cirrhosis patients. We aimed to analyze the risk factors for PVT in liver transplant candidates. Materials and Methods: Dataset for consecutive 165 cirrhotic patients who were evaluated for liver transplantation (LT) were retrospectively analyzed. We sorted...

The differential diagnosis of bloody diarrhea is necessary to specify etiology and plan treatment. Misdiagnosis can lead to catastrophic results with the treatments to be given. In this case report, we present a case of schistosomal colitis mimicking ulcerative colitis in a 26-year-old Guinean male patient diagnosed in 2021.

Background: The effect of hepatic steatosis on the response to antiviral therapy administered in chronic hepatitis B patients is yet to be clarified. In this study, our aim was to determine the effect of hepatic steatosis on the virological response in chronic hepatitis B patients who were treated with entecavir or tenofovir disoproxil fumarate. Me...

BNT162b2 is a messenger RNA vaccine for the prevention of the novel coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 infection. The widespread use of this vaccination has brought along several adverse events. We present a patient with newly diagnosed ulcerative colitis after BNT162b2 vaccine.

Metastases to the pancreas are rare and can be confused with the primary adenocarcinoma of the pancreas. Metastasis of renal pelvis urothelial carcinomas to the pancreas are extremely rare. Endoscopic ultrasound‐guided fine‐needle aspiration (EUS‐FNA) biopsy is a very safe and effective diagnostic method. In this study, we present a 65‐year‐old mal...

Cite this article as: Ak C, Sayar S, Tarikci Kilic E, Kahraman R, Ozturk O, Zemheri IE, et al. EUS-FNA and ROSE in solid lesions of the pancreas; have the same diagnostic efficacy compared to pancreatic sites? North Clin Istanb 2022;9(5):464-469. P ancreatic cancer (PC) is the seventh leading cause of death from cancer worldwide. The 5-year surviva...

Background/aim: Gastric botulinum toxin A (BTX-A) injection is a type of endoscopic obesity treatment option that delays gastric emptying. However, there is little and contradictory information concerning the treatment efficacy of BTX-A injection. This study evaluated the treatment efficacy of BTX-A injection in the treatment of obesity. Material...

Background: Coronavirus disease 2019 (COVID-19) can have a wide clinical spectrum. Objectives: The current study aimed to analyze the clinical and laboratory risk factors of the severe course of disease in patients with COVID-19. Methods: Consecutive patients with a diagnosis of COVID-19 pneumonia were included in the present study. The demographic...

Objectives: The more often the endoscopy sedation is performed, the more the risk of adverse events, and therefore, advanced monitoring becomes more and more essential in endoscopy units. The present study aims to evaluate whether the Bispectral Index (BIS) monitoring is an early predictor of respiratory depression and to determine the compliance b...

Gardner syndrome, a subclass of familial adenomatosis polyposis, is an autosomal dominant disease. Intestinal polyposis, osteomas, and fibromas are characteristic findings of the syndrome. Intestinal polyps have a 100% malignant transformation rate if they are not treated; therefore, early diagnosis and close follow-up are crucial. In this report,...

Objectives: The aim of this study was to evaluate the diagnostic performance of non-invasive fibrosis markers [AST to platelet ratio (APRI), Fibrosis Index based on four factors (FIB-4) İndex, AST/ platelet/GGT/Alpha-fetoprotein (AFP) Index (APGA), FI, Fibro-quotient (FibroQ), AST/ALT ratio (AAR), GGT/Platelet ratio (GPR), Platelet-agephosphatase-...

Background: We aimed to investigate the long-term effects of tenofovir disoproxil fumarate and entecavir treatment on bone mineral density and evaluated the fracture risk assessment tool score in patients with chronic hepatitis B. Methods: A total of 58 chronic hepatitis B patients treated with tenofovir disoproxil fumarate (n = 40) and entecavi...

Background: Celiac disease (CD) is an enteropathy characterized with immune reaction to gliadin protein. Aim: In this study, we aimed to assess effect of CD on coronary microvascular circulation and the association between coronary flow velocity reserve (CFVR) and hs-CRP/Albumin ratio. Material and methods: Study was conducted between March 20...

Objective: The recurring inflammation of mucosal layer of intestines is known as inflammatory bowel disease (IBD), which can be accompanied by nutritional deficiencies. The association between inflammation and coronary artery disease has been established. Coronary flow reserve (CFR), which is an established method to evaluate combined microvascula...

INTRODUCTION: Hepatitis B virus reactivation (HBVR) is an important condition that can be seen under immunosuppressive therapy. HBVR characterized by necroinflammation of the liver and viral replication and may complicated with in liver failure and death. The risk of HBVR in Hbsag-positive patients using tumor necrosis factor inhibitors (Anti-TNF)...

INTRODUCTION: Determining stage of liver fibrosis is crucical for timing of theraphy in chronic hepatitis b (CHB) patients. Also it is important predictor of disease prognosis and response to treatment. Although liver biopsy is the gold standard for demonstrating fibrosis stage, non-invasive fibrosis markers may be useful as an alternative method d...

Background There are several indices and markers of inflammation used to determine disease activity in ulcerative colitis. CRP levels have limited efficiency to show disease activity. Low albumin levels are associated with unresponsiveness to treatment and severe disease activity. In this study we aim to show if there is a correlation of CRP/Albumi...

OBJECTIVE Bile leakage, while rare, can be a complication seen after cholecystectomy. It may also occur after hepatic or biliary surgical procedures. Etiology may be underlying pathology or surgical complication. Endoscopic retrograde cholangiopancreatography (ERCP) can play major role in diagnosis and treatment of bile leakage. Present study was a...

Background: Primary biliary cirrhosis (PBC) is a disease that affects liver with various severity and progression rates. It is important to diagnose advanced stage of the disease to lower liver-related morbidity and mortality. Since liver biopsy is an invasive method, liver biopsy tends to be replaced by noninvasive methods. In this study, we aim...

In this study, our objective was to investigate the relationship between the size of gastroesophageal varices and Child Pugh scores in cirrhotic patients. Retrospectively designed study included 186 cirrhotic patients with gastroesophageal varices who had been followed up by our gastroenterology polyclinic. The patients were classified into three g...

Objectives. Gastric intestinal metaplasia (IM) is frequently encountered and is considered a precursor of gastric adenocarcinoma. In the Van region of Turkey, gastric adenocarcinoma incidence is high but the prevalence of gastric IM is not known. Helicobacter pylori (H. pylori) infection is a main factor leading to atrophy, IM, and cancer developme...

Angiodysplasias are rare but important causes of gastrointestinal bleeding thtat are commonly seen in the colon but rarely in the stomach. Although various endoscopic modalities are used for the treatment of these lesions, argon plasma coagulation is the most commonly used approach. We present a report of two cases of gastric angiodysplasias leadin...

Brunner’s gland adenoma is a rare, benign lesion of the duodenum that is usually small in size and asymptomatic. Here we report a case treated with endoscopic polypectomy following adrenaline injection.

The endoscopic examination is widely used and also the the gold standard in lower gastrointestinal system (LGIS) in the diagnosis and treatment of mucosal pathology. Colon and rectum often hosts premalignant lesions and relatively easily accessible organs. Therefore, colorectal cancer (CRC) is a early detectable disease. And to prevent the developm...

Aim: Colon adenocarcinoma, is the most common cancer in gastrointesinal system (GIS). The whole world is an important cause of morbidity and mortality. TNM and modified Dukes classification which has great importance in the diagnosis and treatment of Colorectal cancer (CRC). TNM and Modified Dukes classification results of histopathological examin...