Stuart Cooper

Stuart Cooper
Environmental Science & Research | ESR · Forensic Biology

Master of Science

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5
Publications
1,247
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149
Citations

Publications

Publications (5)
Article
The analysis of forensic DNA profiles is complicated by the presence of undesirable artefactual peaks such as stutter, pull-up, and dye blobs. We describe the developmental validation of FaSTR™ DNA analysis software, which can assist with the streamlined analysis of forensic DNA profiles. A total of 3403 single-source and mixed DNA profiles generat...
Article
Until recently, forensic DNA profile interpretation was predominantly a manual, time‐consuming process undertaken by analysts using heuristics to determine those genotype combinations that could reasonably explain a recovered profile. Probabilistic genotyping (PG) has now become commonplace in the interpretation of DNA profiling evidence. As the co...
Article
STRmix™ uses several laboratory specific parameters to calibrate the stochastic model for peak heights. These are modelled on empirical observations specific to the instruments and protocol used in the analysis. The extent to which these parameters can be borrowed from laboratories with similar technology and protocols without affecting the accurac...
Article
In 2015 the Scientific Working Group on DNA Analysis Methods published the SWGDAM Guidelines for the Validation of Probabilistic Genotyping Systems [1]. STRmix™ is probabilistic genotyping software that employs a continuous model of DNA profile interpretation. This paper describes the developmental validation activities of STRmix™ following the SWG...
Article
Recently there has been a drive for standardisation of DNA profile interpretation within and between different forensic laboratories. The continuous interpretation software STRmix™ has been adopted for use by laboratories in Australia and New Zealand for profile interpretation. Within this paper we examine the concordance in profile interpretation...

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