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Steven’s research focuses on examining how early-life adversities contributes to onset of neurodevelopmental disorders. He combines bioinformatics, cellular, and molecular approaches to characterise how vertically transferred immune mediators impact inflammatory signalling in the offspring with behavioural and pathological consequences. Simultaneously, he obtains data from longitudinal cohorts to transfer the results found in mice into human settings.
October 2015 - September 2017
University of Trier
Field of study
October 2012 - September 2015
University of Bremen
Field of study
Life-long brain function and mental health are critically determined by developmental processes occurring before birth. During mammalian pregnancy, maternal cells are transferred to the fetus. They are referred to as maternal microchimeric cells (MMc). Among other organs, MMc seed into the fetal brain, where their function is unknown. Here, we show...
Background: The SARS-COVID-19 pandemic and its associated disease control restrictions have in multiple ways affected families with young children, who may be especially vulnerable to mental health problems. Studies report an increase in perinatal parental distress as well as symptoms of anxiety or depression in children during the pandemic. Curren...
Purpose To assess maternal mental health during the first weeks after birth including birth experience, postpartum adjustment to early motherhood and the perception of newborn behaviour, and how this may be influenced by the first wave of the COVID-19 pandemic. Methods Ninety women who gave birth after the first enforcement of nation-wide disease...
During mammalian pregnancy, immune cells are vertically transferred from mother to fetus. The functional role of these maternal microchimeric cells (MMc) in the offspring is mostly unknown. Here we show a mouse model in which MMc numbers are either normal or low, which enables functional assessment of MMc. We report a functional role of MMc in prom...
Milestones of brain development in mammals are completed before birth, which provide the prerequisite for cognitive and intellectual performances of the offspring. Prenatal challenges, such as maternal stress experience or infections, have been linked to impaired cognitive development, poor intellectual performances as well as neurodevelopmental an...
Postpartum follow-up survey of parents with respect to their mental well-being, early parenthood and childhood development under COVID-19 conditions during the first months of life.