Steve Kisely

Steve Kisely
The University of Queensland | UQ · School of Medicine

MD PhD DMedRes

About

625
Publications
66,973
Reads
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14,530
Citations
Introduction
I’m trained in psychiatry, public health and addiction medicine. My research and clinical interests are in epidemiology/pharmaco-epidemiology, chronic disease surveillance, consultation-liaison with both primary & secondary care, health services research (HSR), and physical & psychiatric co-morbidity. These include care pathways (CPs) in primary care and specialist services for mental illness.
Additional affiliations
September 2012 - present
Queensland Health
Position
  • Psychiatrist & Director of Research
September 2012 - present
Queensland Health
Position
  • Psychiatrist & Director of Research
February 2009 - present
The University of Queensland
Position
  • Professor
Education
May 2008 - December 2010
Griffith University
Field of study
  • Psychiatry & Epidemiology
September 1990 - July 1993
September 1988 - July 1990
The University of Manchester
Field of study
  • Psychiatry

Publications

Publications (625)
Article
The poor physical health (including oral health) of people with mental disorders is a global problem. The burden of oral diseases among this group is substantial given their high prevalence and ability to increase the personal, social, and economic impacts of mental disorders. This article summarizes causes of mental disorders and oral diseases, cr...
Article
Full-text available
A large number of early life exposures predict child maltreatment. Using data from a 30-year birth cohort study we examine 12 early life course risk factors of four types of self-reported childhood maltreatment recalled at the 30-year follow-up. Of the 7223 children in the sample at birth, 2425 responded to the Child Trauma Questionnaire at the 30-...
Article
Note: We respectfully refer to Aboriginal and Torres Strait Islander people as Indigenous in this study. Objective: To design and develop an Indigenous specific suicide intervention skills program that focuses on education and intervention training as an effective suicide prevention strategy. Method: Using a co-designed wrap-around framework, w...
Article
Background: Periodontal disease represents a global public health concern, with a disproportionate burden being borne by vulnerable populations. One such group is people with severe mental illness (SMI) and this study examined whether periodontal health is poorer in people with SMI than the general population. Methods: We conducted a systematic...
Article
Background: Most studies on the predictors and effectiveness of community treatment orders (CTOs) are restricted to health-related variables and do not consider forensic contacts as established by criminal justice databases or predictors from birth. We used linked administrative health and criminal justice data for a birth cohort in Queensland, Au...
Article
Objective Although wide variation in the use of community treatment orders mandating treatment for patients with mental illness is well known, there is much less information on the use of forensic orders mandating treatment for patients diverted from justice systems. We therefore examined the use of forensic mental health orders in Australia using...
Article
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Background Clozapine is the most effective medication for treatment–refractory schizophrenia but is associated with significant adverse drug effects, including hypotension and dizziness, which have a negative impact on quality of life and treatment compliance. Available evidence for the management of clozapine-induced hypotension is scant. Objecti...
Article
Background The long-term mental and physical health consequences of childhood maltreatment have been well documented. Less known are the longer-term consequences of childhood maltreatment, specifically the extent to which childhood maltreatment predicts adult life success. Objectives To prospectively assess the extent to which childhood experience...
Article
Background: Evidence shows that depressive symptoms during pregnancy increase the risk of an intervention during delivery (induction, the use of forceps or vacuum, and caesarean sections (CS)). Many women with depression during pregnancy are not identified and therefore will not receive appropriate follow up of their symptoms. We hypothesised that...
Article
Objective Metabolic syndrome is highly prevalent among people with schizophrenia. This study aims to assess the impact on metabolic and attendance outcomes of a co-located, dedicated, endocrinologist-led metabolic clinic in a stand-alone public community mental health service. Methods Demographic and metabolic data on the first 48 consecutive refe...
Article
Objectives There is an increasing interest in combining psilocybin or methylenedioxymethamphetamine with psychological support in treating psychiatric disorders. Although there have been several recent systematic reviews, study and participant numbers have been limited, and the field is rapidly evolving with the publication of more studies. We ther...
Article
Background Perinatal depression is often underdiagnosed; consequently, many women suffer perinatal depression without follow-up care. Screening for depressive symptoms during the perinatal period has been recommended in Australia to increase detection and follow-up of women suffering from depressive symptoms. Screening rates have gradually increase...
Article
Objective Most studies of the association between psychiatric disorders and poor oral health have been conducted in clinical settings. Where available, data from community surveys have generally been cross-sectional or considered anxiety and depression as a consequence of poor oral health, not the other way round. This study therefore used a birth...
Article
Background Health anxiety is a subtype of the older term of hypochondriasis, in which there is worry rather than conviction of having an illness. Information on the association between childhood maltreatment and health anxiety in adulthood often comes from retrospective questionnaires that may be subject to recall bias. There are no prospective dat...
Article
Background: Clozapine is the most effective medication for treatment-refractory schizophrenia but is associated with significant adverse drug reactions, including nocturnal enuresis and urinary incontinence. This side effect can be burdensome and lead to medication nonadherence and psychotic relapse. Evidence to guide treatment of clozapine-induce...
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Background Psychological therapies may play an important role in the treatment of bipolar disorders. Several meta-analyses that examine the effectiveness of psychotherapies for patients with bipolar disorder include conclusions about the impact upon bipolar depression. However, these tend not to consider differences in depression outcome depending...
Article
There is a strong association between self-reported child abuse and subsequent psychosis in retrospective data. Prospective studies of reports to statutory agencies are less common with limited information on people in their 30s. There have also been no comparisons of the influence of self- and agency-reported abuse on psychosis in adulthood. We th...
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Background Experiencing traumatic life events is associated with an increased risk of common mental disorders (CMDs), but studies investigating this association within Indigenous populations are limited. Aims The aim of this study was to investigate associations between trauma and CMDs after controlling for other exposures. Method Trauma exposure...
Article
Objective Most studies that examine psychiatric illness in people who offend have focused on incarcerated samples, with little known about the larger population of individuals with criminal justice system contact. We examine the overlap between proven offences and psychiatric diagnoses with an emphasis on experiences for Indigenous Australians. Me...
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Objectives Research has shown that mindfulness in athletes is associated with positive outcomes. We therefore assessed the effect of mindfulness training on increasing mental toughness (MT) and psychological well-being (PWB). Methods This was a parallel-group, pre-and post-test, randomised controlled pilot trial. Forty-five female athletes from Ir...
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Objective Rates of anxiety have increased during the coronavirus disease 2019 (COVID-19) pandemic, partially attributable to the experience of COVID-19 related concerns. It remains pivotal to determine the implications of such concerns on the severity of anxiety as they may represent opportune targets for public health preventative or therapeutic e...
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Background: The prevalence and prognosis of post-acute stage SARS-CoV-2 infection fatigue symptoms remain largely unknown. Aims: We performed a systematic review to evaluate the prevalence of fatigue in post-recovery from SARS-CoV-2 infection. Method: Medline, Embase, PsycINFO, CINAHL, Web of Science, Scopus, trial registries, Cochrane Central...
Preprint
Full-text available
Objectives To evaluate the utilisation and persistence of antipsychotics for the treatment of schizophrenia in Australia. Methods A retrospective study using the Australian Pharmaceutical Benefits Scheme database of a representative 10% sample. All adults with schizophrenia who were dispensed three or more supplies of oral (including clozapine) or...
Article
Objective: Information on the oral health outcomes of childhood maltreatment in adulthood is limited and reliant on retrospective questionnaires that are subject to recall bias. There are no data from prospective studies using maltreatment reports to statutory agencies. We therefore assessed the effect on dental outcomes and oral health care at 30...
Article
Full-text available
Background There is limited evidence on interventions to minimise weight gain at clozapine commencement. We compared the effect of adjunctive metformin versus placebo at clozapine initiation. Methods People with schizophrenia commencing on clozapine were randomised to either metformin or placebo for 24 weeks. The primary outcome was difference in...
Article
Context Assessing temporal changes in the recorded diagnostic rates, incidence proportions, and health outcomes of substance-related disorders (SRD) can inform public health policymakers in reducing harms associated with alcohol and other drugs. Objective To report the annual and cumulative recorded diagnostic rates and incidence proportions of SR...
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This editorial discusses the psychological effects of isolation and quarantine in terms of both the SARS-CoV-2 (COVID-19) pandemic and previous epidemics in the past 20 years. Although much of the literature is based on healthcare settings, there is emerging evidence from home or hotel quarantine, particularly concerning international travellers. R...
Article
Objective Psychiatric patients have increased rates of comorbid physical illness. There are less data on dental disease, especially decay, despite risk factors including lifestyle and psychotropic side effects such as xerostomia. We therefore undertook an umbrella review of all meta-analyses on the association between mental illness and oral health...
Article
Objectives Clozapine levels may be a more useful predictor of therapeutic response than the dose, given the variability in clozapine metabolism between individuals. We therefore systematically reviewed and meta-analysed the impact of clozapine levels on response and/or relapse to provide guidance on optimal clozapine levels. Methods We systematica...
Article
Objective: Existing evidence on factors associated with community treatment order placement is largely restricted to administrative data. We utilised the data from a large nationally representative sample to compare the demographic, clinical, social functioning, substance use and service utilisation profiles of people living with psychosis under c...
Article
Background Mindfulness-based cognitive therapy (MBCT) is a promising adjunctive treatment for adolescents and young adults (AYAs) with Inflammatory Bowel Disease (IBD) and comorbid depression. Objectives This pilot randomised controlled trial (RCT) aimed to evaluate feasibility and efficacy of an adapted MBCT program for AYA, aged 16–29, with IBD....
Article
Full-text available
Objective To assess the impact, in the Australian setting, of the COVID-19 lockdown on antipsychotic supplies for patients with schizophrenia following a prescription from a new medical consultation when compared to the same periods in the previous 4 years. A secondary objective was to assess the volume of all antipsychotic supplies, from new and r...
Article
Background: Attendances at emergency departments (EDs) for dental conditions are unnecessary and come at a significant cost to health services. Methods: A population-based record-linkage analysis of a retrospective cohort over 2 years across state-based facilities in Queensland. This was to determine if people with mental illness were more likel...
Article
The Queensland Government issued a policy directive to lock all acute adult public mental health inpatient wards in 2013. Despite criticism from professional bodies and advocacy for an alternative, the policy has been retained to this day. A blanket directive to treat all psychiatric inpatients in a locked environment without individualised conside...
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Objective: To generate outcomes for the development of a culturally appropriate mental health treatment model for Indigenous Australians with depression. Methods: Three focus group sessions and two semi-structured interviews were undertaken over six months across regional and rural locations in South West Queensland. Data were transcribed verbat...
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Introduction Colorectal cancer (CRC) mortality is significantly higher in those with severe mental illness (SMI) compared with the general population, despite similar incidence rates, suggesting that barriers to optimal screening and cancer care may contribute to disparities in CRC mortality in those with SMI. This study aims to compare participati...
Article
Background and Aims Cannabis use is increasing among women of reproductive age, warranting a greater understanding of the impact of prenatal cannabis use on offspring developmental outcomes. We tested for a potential relationship between prenatal cannabis use disorders (CUD) and offspring educational outcomes across primary and secondary school. D...
Article
Background Treatment-resistant schizophrenia (TRS) is associated with high levels of functional impairment, healthcare usage and societal costs. Cross-sectional studies may overestimate TRS rates because of selection bias. Aims We aimed to quantify TRS rates by using first-episode cohorts to improve resource allocation and clozapine access. Metho...
Preprint
Background The prevalence and prognosis of post-acute stage SARS-CoV-2 infection fatigue symptoms remain largely unknown.AimsWe performed a systematic review to evaluate the prevalence of fatigue in post-recovery from SARS-CoV-2 infection.Method Medline, Embase, PsycINFO, CINAHL, Web of Science, Scopus, trial registries, Cochrane Central Register o...
Preprint
Full-text available
Background The prevalence and prognosis of post-acute stage SARS-CoV-2 infection fatigue symptoms remain largely unknown. Aims We performed a systematic review to evaluate the prevalence of fatigue in post-recovery from SARS-CoV-2 infection. Method Medline, Embase, PsycINFO, CINAHL, Web of Science, Scopus, trial registries, Cochrane Central Regis...
Article
Objectives: To examine the association between child maltreatment (abuse and neglect) in one sibling and that in another as well as associated risk factors. Methods: The participants were 520 sibling pairs enrolled in a population-based birth cohort study in Brisbane, Australia (N = 1040). Exposure to suspected child maltreatment was measured by...
Article
Full-text available
Objective Trauma is reported by 70% of the global population and 4% of those exposed develop post-traumatic stress disorder (PTSD), but data from Indigenous populations are limited. We aimed to determine the prevalence, types and age of occurrence of traumatic events among community-living Indigenous Australians and associations with PTSD. Design...
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Background People with schizophrenia have a 15–20-year reduction in life expectancy, driven in part by the metabolic effects of antipsychotics. Clozapine is associated with the highest rates of weight gain. As clozapine remains the most effective antipsychotic for treatment-resistant schizophrenia (TRS), identifying treatments to ameliorate clozapi...
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Full-text available
Aims Limited information exists about the prevalence of psychiatric illness for Indigenous Australians. This study examines the prevalence of diagnosed psychiatric disorders in Indigenous Australians and compares this to non-Indigenous Australians. The aims were to: (1) determine prevalence rates for psychiatric diagnoses for Indigenous Australians...
Article
Objective A recent meta-analysis of 17 randomized, controlled trials (RCTs) showed that Short-term Psychodynamic Psychotherapy (STPP) for functional somatic disorders (FSD) reduced somatic symptoms compared to wait list, minimal treatment, and treatment-as-usual controls. A clinically important yet unanswered question is how much improvement patien...
Article
Objective: Obesity and adverse metabolic outcomes in patients with severe mental illness are clinically significant but potentially preventable. Importantly, the evidence for switching to antipsychotics to reduce cardiometabolic burden is unclear. Method: PubMED, Embase, PsycINFO, and Cochrane were searched from inception to March 8, 2020. Artic...
Article
Background Retrospective studies show a strong association between child abuse and subsequent psychiatric morbidity. Prospective studies are less common with conflicting data in young adults. We assessed the effect on psychological outcomes at 30-year follow-up of prospective agency notifications compared to retrospective self-reports of childhood...
Article
Background Indigenous peoples and those from non-Caucasian, poorer or rural backgrounds are at greater risk of emergency department (ED) presentations for non-traumatic or avoidable dental conditions. There is no information on people with mental illness. Objective To compare avoidable dental ED admissions in psychiatric patients with those of the...
Article
Introduction Administrative health databases (AHD) are critical to guide health service management and can inform the whole spectrum of substance‐related disorders (SRD). This study estimates prevalence and mortality rates of SRD in administrative health databases. Methods The Quebec Integrated Chronic Disease Surveillance System consists of linke...
Article
Antenatal depression is the strongest predictor for postpartum depression including psychiatric admission. Universal screening for depressive symptoms during pregnancy may increase the detection of clinical depression and reduce consequent morbidity. We therefore hypothesised that antenatal screening for depressive symptoms could reduce the risk of...
Article
Introduction Retrospective studies show a strong association between self-reported child abuse and subsequent tobacco use. Prospective studies using reports to statutory agencies are less common with limited information on people in their 30s. In addition, there have been no comparisons of the effect of self- and agency-reported abuse on smoking. W...
Article
To compare the post-discharge outcomes of people admitted to community-based residential mental health rehabilitation facilities subject to a Community Treatment Order (CTO) who do and do not have this order discontinued prior to discharge. People subject to a CTO who were admitted across five Community Care Units (CCUs) in Queensland, Australia b...
Article
Individuals with mental illness are overrepresented in custodial settings. We examine the overlap between incarceration and diagnosed mental illness in a population‐based cohort born in Queensland in 1990. Data were extracted when the cohort was 23 or 24 years old. The population included 44,952 individuals (6.3 per cent Indigenous Australians, 45....
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Full-text available
Aims The use of mechanical restraint is a challenging area for psychiatry. Although mechanical restraint remains accepted as standard practice in some regions, there are ethical, legal and medical reasons to minimise or abolish its use. These concerns have intensified following the Convention on the Rights of Persons with Disabilities. Despite nati...
Article
Objectives The aim of this study was to identify current physical health guidelines for severe mental illness (SMI) and appraise them using the Appraisal of Guidelines for Research and Evaluation (AGREE) II Instrument. Methods Relevant research databases and grey literature were systematically searched to identify physical health guidelines for peo...
Article
Objectives A major challenge for hospitals and clinicians is the early identification of neonates at risk of developing adverse conditions. We develop a model based on routinely collected administrative data, which accurately predicts two common disorders among early term and preterm (<39 weeks) neonates prior to discharge. Study design The data in...
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Full-text available
Objectives: Mindfulness-based cognitive therapy (MBCT) is effective in treating psychosocial comorbidities in inflammatory bowel disease (IBD); however, there have been no qualitative studies of MBCT experiences among youth with IBD. We aimed to examine the experiences of youth with IBD and depression who completed an adapted MBCT group programme,...
Article
Background There is little known about how two sources of child maltreatment reports correspond, specifically for emotional, physical, sexual abuse and emotional or physical neglect. Objective To compare agency and self-reports of child maltreatment and determine whether they are predicted by similar early life course adverse experiences. Particip...
Article
Introduction and Aims Retrospective studies have shown a strong association between experiencing maltreatment in childhood and subsequent illicit substance or alcohol use. Prospective studies are rarer, with limited data following subjects into adulthood. We report findings from a prospective record‐linkage analysis, which examines whether notified...
Article
Background Cognitive behavioural therapy for psychosis (CBTp), an effective treatment for people with schizophrenia, may have a role in clozapine refractory schizophrenia. Aims A systematic-review and meta-analysis on the impact of CBTp on psychotic symptoms in people on clozapine. Methods We searched PubMed, Embase, PsycInfo, CINAHL and Cochrane...
Article
Objective Withdrawal from psychoactive medication such as quetiapine is a well-documented phenomenon. Despite the extensive use of quetiapine, there have been few studies into the presence of discontinuation symptoms. We therefore performed a systematic review of published literature for evidence of quetiapine withdrawal or symptoms associated with...
Article
The Convention on the Rights of Persons with Disabilities (2006) (CRPD) has been instrumental for initiating and shaping the reform of mental health legislation in many countries, including the eight Australian jurisdictions. Multiple approaches have been proposed to assess and monitor the compliance of States Parties' mental health legislation wit...
Article
Background Lithium in drinking water may have significant mental health benefits. We investigated the evidence on the association between lithium concentrations in drinking water and their neuropsychiatric outcomes. Methods We conducted a systematic review and meta-analysis and searched Pubmed, Embase, Web of Science, PsycINFO and CINAHL up to 19...
Article
Potential long-lasting adverse effects of child maltreatment have been widely reported, although little is known about the distinctive long-term impact of differing types of maltreatment. Our objective for this special article is to integrate findings from the Mater-University of Queensland Study of Pregnancy, a longitudinal prenatal cohort study s...