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Stephen Ian Foote

Stephen Ian Foote


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A systems engineer of 45 years experience, i have an interest in the evolution and function of biological systems. I Suggest current hair research ignores a fundamental growth control that must be involved in hair follicle enlargement. I have added my review of historic and current hair research, that describes the implications of this missed connection.


Publications (7)
Full-text available
Full-text available
This short article is intended to outline a clear contradiction in one area of peer reviewed research, to the widely accepted science in the field. This issue has implications in Mammalian and Human evolution, and some serious gender related diseases.
Androgen-related changes in hair growth represent something of a mystery. Through the action of dihydrotestosterone (DHT), hair growth is increased in specific areas of the body. Elevated levels of DHT produce a general increase over the larger part of the body, often accompanied by hair loss in specific areas of the scalp. Because of this 'opposit...
It is accepted that the detailed mechanisms of changes in human hair growth patterns are poorly understood. It is this uncertainty that has encouraged many charlatans to operate in this area. From my perspective as an engineer, however, there is a simple mechanism that makes sense of these changes. I suggest this mechanism is closely connected with...


Question (1)
As a systems engineer, I am a believer in the advantages of the systems approach as described by Professor Denis Noble and colleagues. Here I propose what I consider to be an example of how this approach can answer the questions in physiology the molecules alone cannot. I would respectfully request comments and criticisms on my arguments.
For reasons of copyright, I could not directly use the diagrams I wanted in the paper. I have a pdf version that includes these, but I don't seem able to attach this here. They say a pictures worth a thousand words, and visualization is important to my proposal..
My argument could be called simplistic, but this is the whole point. I am not concerned with the genetics, rather the structures the genes ultimately produce and how these interact. One thing is for sure, the genes cannot produce structures that can avoid the basic laws of physics. I do not attribute any physical characteristics to the structures involved that are not already accepted. All I am doing here is making a simple connection with these structures and known tissue growth controls.
The proposal involves the evolution and function of hair growth. Hair growth research has traditionally involved the reductionist approach of looking at molecular changes. The implicated mechanism of my proposal, demonstrates that any molecular changes are downstream and not causal. This answers the questions that the molecular approach has failed to do in around 60 years of trying. There is a lot more to be said about the implications of the indicated mechanism here. I will do my best to answer any questions or points relating to this.
For me, the most interesting thing here is evolutions use of "Hydraulics" in the function of biological systems. Life evolved in fluid, the fluid came first as it were. If evolution is about advantages, there are advantages to be had from hydraulics, as this mechanism demonstrates. I think there are other examples of hydraulics in human physiology that are important, and should be discussed.
I look forward to comments.


Project (1)
To demonstrate that modern Human hairlessness and increased sweating ability,, was a simple adaptation from an already existing feature in mammals and primates.