Stephanie Seneff

Massachusetts Institute of Technology | MIT · Department of Electrical Engineering and Computer Science

Lutein dietary rich supplementation has the potential to alleviate inflammatory processes caused by SARS-CoV-2 spike protein. Lutein can alleviate oxidative and nitrosamine stress found in Post COVID 19 and mRNA vaccination Injury syndromes. Best way to provide diet rich lutein is in the Extra Virgin Olive Oil (EVOO), when lutein is maintained stab...

As a result of the spread of SARS-CoV-2, a global pandemic was declared. Indiscriminate COVID-19 vaccination has been extended to include age groups and naturally immune people with minimal danger of suffering serious complications due to COVID-19. Solid immuno-histopathological evidence demonstrates that the COVID-19 genetic vaccines can display a...

We report on an aggressive, infiltrating, metastatic, and ultimately lethal basaloid type of carcinoma arising shortly after an mRNA vaccination for COVID-19. The wife of the patient, since deceased, gave the consent for publishing the case. The malignancy was of cutaneous origin and the case showed symptoms consistent with Bell's palsy and trigemi...

The SARS-CoV-2 spike protein is a long-lasting foreign pathogenic protein found in cells and tissues after COVID-19 respiratory illness and COVID-19 vaccination. The spike protein incites an inflammatory response and is a potent activator of nuclear factor kappa light chain enhancer of activated B cells (NF-κB). It can adversely impact any of the v...

The SARS-CoV-2 spike protein is a long-lasting foreign pathogenic protein found in cells and tissues after COVID-19 respiratory illness and COVID-19 vaccination. The spike protein incites an inflammatory response and is a potent activator of nuclear factor kappa light chain enhancer of activated B cells (NF-κB). It can adversely impact any of the v...

The SARS-CoV-2 spike protein is a long-lasting foreign pathogenic protein found in cells and tissues after COVID-19 respiratory illness and COVID-19 vaccination. The spike protein incites an inflammatory response and is a potent activator of nuclear factor kappa light chain enhancer of activated B cells (NF-κB). It can adversely impact any of the v...

As a result of the spread of SARS-CoV-2, a global pandemic was declared. Indiscriminate COVID-19 vaccination has been extended to include age groups and naturally immune people with minimal danger of suffering serious complications due to COVID-19. Solid immuno-histopatholog-ical evidence demonstrates that the COVID-19 genetic vaccines can display...

Human prion protein and prion-like protein misfolding are widely recognized as playing a causal role in many neurodegenerative diseases. Based on in vitro and in vivo experimental evidence relating to prion and prion-like disease, we extrapolate from the compelling evidence that the spike glycoprotein of SARS-CoV-2 contains extended amino acid sequ...

Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and prions use common pathogenic pathways to induce toxicity in neurons. Infectious prions rapidly activate the p38 mitogen activated protein kinase (MAPK) pathway, and SARS-CoV-2 spike proteins rapidly activate both the p38 MAPK and c-Jun NH2-terminal kinase (J...

The SARS-CoV-2 spike protein and prions use common pathogenic pathways to induce toxicity in neurons. Infectious prions activate the p38 mitogen activated protein kinase (MAPK) pathway, and SARS-CoV-2 spike proteins induce the p38 MAPK and c-Jun NH2-terminal kinase (JNK) pathways through toll-like receptor signaling, indicating the potential for si...

Background The findings of a sequence embedded in Human DNA that was almost identical to a sequence in the SARS-CoV-2 genome, and the identification of plausible integration of SARS-CoV-2 RNA into human DNA by endogenous reverse transcriptase activity expressed by Long Interspersed Nuclear Element (LINE)-1 (17% of Human DNA) have raised concerns ab...

Background: The integration of genetic code from RNA viruses into host DNA, once thought to be a rare or even impossible phenomenon, is now recognized as probable. The Long Interspersed Nuclear Element (LINE)-1 mediated mechanism of insertion implies that many viral RNAs (apart from retroviral) can be reverse transcribed and then stably incorporate...

Background The findings of a sequence embedded in Human DNA that was almost identical to a sequence in the SARS-CoV-2 genome, and the identification of plausible integration of SARS-CoV-2 RNA into human DNA by endogenous reverse transcriptase activity expressed by Long Interspersed Nuclear Element (LINE)-1 (17% of Human DNA) have raised concerns ab...

Background: Recent research suggests that Tourette Syndrome and tic-related disorders can be alleviated by dietary and other CAM (Complementary and Alternative Medicine) interventions. In this study we explore the hypothesis that these disorders and associated comorbidities stem from abnormalities in gut microbiome (gut dysbiosis). The GAPS Nutriti...

The mRNA SARS-CoV-2 vaccines were brought to market in response to the public health crises of Covid-19. The utilization of mRNA vaccines in the context of infectious disease has no precedent. The many alterations in the vaccine mRNA hide the mRNA from cellular defenses and promote a longer biological half-life and high production of spike protein....

The Initial Common Pathway of Inflammation, Disease, and Death, Abstract and Poster presented to American Chemical Society June 10-13, 2012, 86th Colloid & Surface Science Symposium, Johns-Hopkins University, Baltimore, Md, USA Presentation Abstract Title: The Initial Common Pathway of Inflammation, Disease, and Death Presentation Monday, Jun 11...

The mRNA SARS-CoV-2 vaccines were brought to market in response to the widely perceived public health crises of Covid-19. The utilization of mRNA vaccines in the context of infectious disease had no precedent, but desperate times seemed to call for desperate measures. The mRNA vaccines utilize genetically modified mRNA encoding spike proteins. Thes...

A growing amount of research highlights the relationship between damaged gut microbiome and chronic illnesses - mental and physical. Healing the gut is becoming a priority in treating any chronic disease. The GAPS Nutritional Protocol has been designed for this purpose and has been used all over the world for twenty years. It has yielded successful...

Background: PANDAS is a debilitating psychiatric condition that appears suddenly in childhood characterized by obsessive and compulsive behaviour, anxiety, fear, phobias, tics, irritability, mood swings, developmental regression, sleep issues and hallucinations. It is often hypothesized that this range of symptoms is caused by an autoimmune respons...

Operation Warp Speed brought to market in the United States two mRNA vaccines, produced by Pfizer and Moderna. Interim data suggested high efficacy for both of these vaccines, which helped legitimize Emergency Use Authorization (EUA) by the FDA. However, the exceptionally rapid movement of these vaccines through controlled trials and into mass depl...

Biological water exists in at least two distinct forms: bulk and interfacial. While the former possesses widely understood properties , little has been written about the formation , maintenance, and functional role of interfacial water in living systems. In this paper we equate interfacial water with Exclusion Zone (EZ) water described by Pol-lack...

Chronic kidney disease of unknown etiology (CKDu) is a global epidemic. Sri Lanka has experienced a doubling of the disease every 4 or 5 years since it was first identified in the North Central province in the mid-1990s. The disease primarily affects people in agricultural regions who are missing the commonly known risk factors for CKD. Sri Lanka i...

Quantum entanglement is a phenomenon in theoretical physics that happens when pairs or groups of particles are generated in such a way that the quantum state of each particle cannot be described independently of the others, even when the particles are separated by a large distance. Instead, a quantum state must be described for the system as a whol...

On 28 April 2018 the European Parliament voted for a complete and permanent ban on all outdoor uses of the three most commonly used neonicotinoid pesticides. With the partial exception of the state of Ontario, Canada, governments elsewhere have failed to take action. Below is a letter, signed by 232 scientists from around the world, urgently callin...

Mesoamerican Nephropathy (MeN), also known as Chronic Kidney Disease of unknown etiology (CKDu), is an unusual form of kidney disease affecting agricultural workers in Central America. Its prevalence is alarmingly high among young male sugarcane workers in Nicaragua and El Salvador. The absence of known etiologies for CKD, such as hypertension and...

Mesoamerican nephropathy (MeN), also known as chronic kidney disease of unknown etiology (CKDu), is an unusual form of kidney disease not associated with diabetes, hypertension, or glomerular nephritis. It has a number of known risk factors, none of which adequately explain the skyrocketing prevalence of the disease among sugarcane workers in El Sa...

p>A rising epidemic among Americans threatens to disrupt the new US administration’s promise of affordable health insurance for all. The epidemic consists of a dramatic and ongoing increase in the incidence of autoimmune diseases (AD) across the populations of nearly all Western countries, diagnosed under approximately 100 different disease labels,...

Usage of the herbicide glyphosate on core crops in the USA has increased exponentially over the past two decades, in step with the exponential increase in autoimmune diseases including autism, multiple sclerosis, inflammatory bowel disease, type 1 diabetes, coeliac disease, neuromyelitis optica and many others. In this paper we explain how glyphosa...

Despite enjoying a high standard of living, the United States ranks 46th among nations reporting infant survival rates to the World Health Organization. Among factors that increase infant mortality are environmental toxicants. Toxic metals such as mercury, aluminum, and lead interact synergistically with fluoride compounds to produce metal fluoride...

Despite enjoying a high standard of living, the United States ranks 46th among nations reporting infant survival rates to the World Health Organization. Among factors that increase infant mortality are environmental toxicants. Toxic metals such as mercury, aluminum, and lead interact synergistically with uoride compounds to produce metal fuoride c...

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease involving several protein mutations in glycine-rich regions with limited treatment options. 90-95% of all cases are non-familial with epidemiological studies showing a significant increased risk in glyphosate-exposed workers. In this paper, we propose that glyphosate, the acti...

Glyphosate, a synthetic amino acid and analogue of glycine, is the most widely used biocide on the planet. Its presence in food for human consumption and animal feed is ubiquitous. Epidemiological studies have revealed a strong correlation between the increasing incidence in the United States of a large number of chronic diseases and the increased...

Many types of chemicals, including pesticides and pharmaceutical drugs, cause metabolic acidosis and mitochondrial disorder. We provide evidence from the scientific literature that glyphosate can be metabolized by humans, that it disrupts the intestinal microbiota, causes severe metabolic acidosis when ingested in high doses and leads to mitochondr...

Glyphosate is the most widely used herbicide on the planet, and its increasing use over time in the United States aligns well with the increasing rates of autism determined by the Centers for Disease Control. Based on the known mechanism of glyphosate toxicity, we hypothesize that a pregnant woman's exposure at mid-pregnancy to glyphosate-formulate...

Osteonecrosis of the jaw (ONJ), a rare side effect of bisphosphonate therapy, is a debilitating disorder with a poorly understood etiology. FDA's Adverse Event Reporting System (FAERS) provides the opportunity to investigate this disease. Our goals were to analyze FAERS data to discover possible relationships between ONJ and specific conditions and...

An analysis of selected datasets from the FDA’s drug Adverse Event Reporting System (FAERS) leads us to hypothesize that glyphosate contamination in both food and drugs is a major contribu- tor to chronic and acute kidney failure respectively. In chronic kidney failure, glyphosate-induced pancreatitis results in the release of trypsin, causing a le...

In consideration of the “universal nonspecific mesenchymal reaction”, also referred to as the Sanarelli-Shwartzman phenomenon, we raise the question: how can the SULTs (sulfotransferases) and PAPS molecules assemble and perform the multitude of sulfation reactions required to produce all of the many posttranslational modifications of mucopolysaccha...

We propose that the Ascorbate radical and its 2-O-substituted-L-ascorbate radicals provide lifelong modulators of redox kinetics and universal group transfer catalysts in inflamed tissue during the Sanarelli-Shwartzman Phenomenon, DIC syndrome, cancer, sepsis, neurodevelopment, and atherosclerosis. We propose that the Ascorbate radical is capable o...

Gamma-glutamyltransferase (GGT) is a well-established serum marker for alcohol-related liver disease. However, GGT’s predictive utility applies well beyond liver disease: elevated GGT is linked to increased risk to a multitude of diseases and conditions, including cardiovascular disease, diabetes, metabolic syndrome (MetS), and all-cause mortality....

The authors wish to make the following correction to their paper [1]. The correct reference 190 in the reference list should be: [...]

A new hypothesis as to the organizational basis of cells, organism, and nervous system - the “fractal dimension” - is presented. Alteration in biological water dynamics likely precedes the onset of inflammation, maternal immune activation, and IL-6 elevations, in autism. Exogenous interfacial water stress (EIWS) leads to concomitant disruption of m...

A significant degradation in the health of wild animals in Montana has been recorded over the past two decades. We surmise that the health issues are related to pesticide exposure. We present some of the evidence of the deterioration of the health in wildlife, which we used to inspire investigations on human health in the US population. While the a...

Despite a vast literature, atherosclerosis and the associated ischemia/reperfusion injuries remain today in many ways a mystery. Why do atheromatous plaques make and store a supply of cholesterol and sulfate within the major arteries supplying the heart? Why are treatment programs aimed to suppress certain myocardial infarction risk factors, such a...

Manganese (Mn) is an often overlooked but important nutrient, required in small amounts for multiple essential functions in the body. A recent study on cows fed genetically modified Roundup-Ready feed revealed a severe depletion of serum Mn. Glyphosate, the active ingredient in Roundup , has also been shown to severely deplete Mn levels in plants....

Because of the abundance of aluminum in the Earth’s crust, it was regarded as harmless before its use in products became prevalent. Humans are exposed to aluminum from food, water, medicinals, vaccines, cosmetics, and industrial exposure. However, Al is toxic to living systems and has no physiological role in biological systems. Beginning with the...

Glyphosate is the active ingredient in the pervasive herbicide, Roundup, and its usage, particularly in the United States, has increased dramatically in the last two decades, in step with the widespread adoption of Roundup®-Ready core crops. The World Health Organization recently labelled glyphosate as “probably carcinogenic.” In this paper, we rev...

Many neurological diseases, including autism, depression, dementia, anxiety disorder and Par-kinson's disease, are associated with abnormal sleep patterns, which are directly linked to pineal gland dysfunction. The pineal gland is highly susceptible to environmental toxicants. Two pervasive substances in modern industrialized nations are aluminum a...

The causes of autism spectrum disorder (ASD) are not well understood. Only a minority of cases are explainable by specific abnormalities in DNA sequence, whereas the majority are widely assumed to be linked to epigenetic effects, and/or likely impacted by environmental factors. Here, we postulate autism causation via environmental and/or dietary so...

Bio-event extraction is an important phase towards the goal of extracting biological networks from the scientific literature. Recent advances in word embedding make computation of word distribution more ef- ficient and possible. In this study, we investigate methods bringing distributional characteristics of words in the text into event extraction...

Over the last 200 years, mining, smelting, and refining of aluminum (Al) in various forms have increasingly exposed living species to this naturally abundant metal. Because of its prevalence in the earth's crust, prior to its recent uses it was regarded as inert and therefore harmless. However, Al is invariably toxic to living systems and has no kn...

The number of sports-related concussions has been steadily rising in recent years. Diminished brain resilience syndrome is a term coined by the lead author to describe a particular physiological state of nutrient functional deficiency and disrupted homeostatic mechanisms leading to increased susceptibility to previously considered innocuous concuss...

Over the last 200 years, mining, smelting, and refining of aluminum (Al) in various forms have increasingly exposed living species to this naturally abundant metal. Because of its prevalence in the earth’s crust, prior to its recent uses it was regarded as inert and therefore harmless. However, Al is invariably toxic to living systems and has no kn...

ABSTRACT Celiac disease, and, more generally, gluten intolerance, is a growing problem worldwide, but especially in North America and Europe, where an estimated 5% of the population now suffers from it. Symptoms include nausea, diarrhea, skin rashes, macrocytic anemia and depression. It is a multifactorial disease associated with numerous nutrition...

Celiac disease, and, more generally, gluten intolerance, is a growing problem worldwide, but especially in North America and Europe, where an estimated 5% of the population now suffers from it. Symptoms include nausea, diarrhea, skin rashes, macrocytic anemia and depression. It is a multifactorial disease associated with numerous nutritional defici...

This paper postulates that water structure is altered by biomolecules as well as by disease-enabling entities such as certain solvated ions, and in turn water dynamics and structure affect the function of biomolecular interactions. Although the structural and dynamical alterations are subtle, they perturb a well-balanced system sufficiently to faci...

Glyphosate, the active ingredient in Roundup ® , is the most popular herbicide used worldwide. The industry asserts it is minimally toxic to humans, but here we argue otherwise. Residues are found in the main foods of the Western diet, comprised primarily of sugar, corn, soy and wheat. Glyphosate's inhibition of cytochrome P450 (CYP) enzymes is an...

This paper makes two claims: (1) autism can be characterized as a chronic low-grade encephalopathy, associated with excess exposure to nitric oxide, ammonia and glutamate in the central nervous system, which leads to hippocampal pathologies and resulting cognitive impairment, and (2), encephalitis is provoked by a systemic deficiency in sulfate, bu...

Multisystem interactions are well established in neurological disorders, in spite of conventional views that only the central nervous system (CNS) is impacted. We review evidence for mutual interactions between the immune and nervous systems and show how these seem to be implicated in the origin and progression of nervous system disorders. Well-est...

Theoretical inferences, based on biophysical, biochemical, and biosemiotic considerations, are related here to the pathogenesis of cardiovascular disease, diabetes, and other degenerative conditions. We suggest that the “daytime” job of endothelial nitric oxide synthase (eNOS), when sunlight is available, is to catalyze sulfate production. There is...

There are many Web-based platforms where people could share user-generated content such as reviews, posts, blogs, and tweets. However, online communities and social networks are expanding so rapidly that it is impossible for people to digest all the information. To help users obtain information more efficiently, both the interface for data access a...

Autism is a brain disorder involving social, memory, and learning deficits, that normally develops prenatally or early in childhood. Frustratingly, many research dollars have as yet failed to identify the cause of autism. While twin concordance studies indicate a strong genetic component, the alarming rise in the incidence of autism in the last thr...

In a recent paper, we proposed that a contributing factor in autism is a deficiency in cholesterol sulfate supply. In this paper, we investigate a link between preeclampsia and subsequent autism in the child, and we hypothesize that both conditions can be attributed to a severe depletion of cholesterol sulfate. Through studies on the Vaccine Advers...

Autism is a condition characterized by impaired cognitive and social skills, associated with compromised immune function. The incidence is alarmingly on the rise, and environmental factors are increasingly suspected to play a role. This paper investigates word frequency patterns in the U.S. CDC Vaccine Adverse Events Reporting System (VAERS) databa...

In reviewing the literature pertaining to interfacial water, colloidal stability, and cell membrane function, we are led to propose that a cascade of events that begins with acute exogenous surfactant-induced interfacial water stress can explain the etiology of sudden death syndrome (SDS), as well as many other diseases associated with modern times...

Colloidal & Surface Forces We propose, herein, that exogenous interfacial water stress (EIWS) is the initial common pathway for inflammation, disease, and death. We further propose that acute coronary syndromes and myocardial infarction are the result of a cascade triggered by EIWS-induced activation of platelets and the coagulation pathway. The st...

This paper presents a generic web-based dialogue game framework, "Mercurial", for language learning. The system capabilities are demonstrated within a flight domain application. The system randomly generates a flight-booking scenario according to the current difficulty level. The student accomplishes the scenario by interacting with the system thro...