Stephane Rothen

Hôpitaux Universitaires de Genève | HUG · Service d'addictologie

History and Objectives This study addresses the increasing global concerns surrounding Internet gaming disorder (IGD) by exploring their connection to physical activity (PA) as a potential preventive and early intervention measure. The research aims to examine the relationship between PA and the progression of IGD. Methods Longitudinal data from t...

Introduction While research on drug use motives has primarily focused on widely used substances like alcohol, tobacco, and cannabis, understanding the motivations behind MDMA use is crucial for developing targeted therapeutic, preventive, and harm reduction strategies. Objectives The objective of this study is to present the findings of an online...

Dans cet article, nous avons pour objectif de décrire un modèle interdisciplinaire de psychothérapie assistée par psychédéliques (PAP) que nous avons développé dans un cadre institutionnel aux hôpitaux universitaires de Genève. La psychothérapie assistée par psychédéliques (PAP) est une approche psychothérapeutique exploitant l’altération de l’état...

This article proposes 10 points considered essential on the ethics associated with the practice of psychotherapy assisted by psychedelics (PAP) : 1) respect of the legal framework (LStup) of the use of psychotropic drugs ; 2) adequately manage psychedelics (storage, production and safety) ; 3) announce adverse effects to the competent authority ; 4...

Introduction: There is considerable effort in legalizing recreational use of cannabis globally. The successful implementation of a program of regulated access to recreational cannabis (PRAC) depends on the consumers' engagement. The aim of this study was to examine the acceptability of twelve different regulatory aspects by cannabis users includin...

Case report of a patient with GAD and claustrophobia who underwent exposure therapy using psilocybin-assisted psychotherapy. The patient had failed to respond to conventional psychotherapeutic treatment. After three sessions of psilocybin-assisted psychotherapy, the patient experienced a reduction in anxiety and fear associated with closed spaces,...

A scientometric analysis was realized to outline clinical research on psychedelics over the last century. Web of Science Core Collection was searched up to March 18, 2022, for publications on psychedelics. Network analyses and bibliometrics were combined, to identify research themes and trends with Bibliometrix and CiteSpace. The primary aim was to...

Gaming disorder (GD) is a new health condition still requiring a lot of evidence established around its underlying and related psychological mechanisms. In our study we focused on Massively Multiplayer Online Role Playing Games (MMORPGs), a specific very popular and engaging game genre, to determine that benefit, motivation and control aspects coul...

Craving and impulsivity are addiction components which explain why heroin-dependant individuals (HDI), continue using heroin despite not wanting to do so. Opioid maintenance treatment (OMT), such as slow-release oral morphine (SROM), is the most effective treatment for opioid dependence. However, the impact of SROM on craving and impulsivity remain...

Opioid maintenance treatment (OMT) is the most effective treatment for opioid use disorder (OUD). However, persistence of cocaine abuse in the population receiving OMT can be a considerable clinical concern. The primary aim of our study was to determine whether individuals with OUD receiving OMT exhibit higher impulsivity when presenting concurrent...

World of Warcraft (WoW) is a popular Massively Multiplayer Online Role-Playing Games (MMORPG) in which players create an avatar that evolves and interacts with other avatars in a persistent virtual world. In a previous study about motivations to play MMORPG, participants were asked whether they agree or not to have their avatar monitored on the lon...

Suicidal behavior (SB) is a major problem in patients with substance use disorders (SUDs). However, little is known about specific SB risk factors in this population, and pathogenetic hypotheses are difficult to disentangle. This study investigated some SB and SUD-related endophenotypes, such as impulsivity, aggression, trait anger, and risk-taking...

Intuitive eating has been described as representing a positive relationship with food that can support health. However, to date, most of the extant research on intuitive eating has been conducted among young women, limiting our understanding of how intuitive eating can contribute to supporting health in aging women. This study aimed to bridge this...

In this crowdsourced initiative, independent analysts used the same dataset to test two hypotheses regarding the effects of scientists' gender and professional status on verbosity during group meetings. Not only the analytic approach but also the operationalizations of key variables were left unconstrained and up to individual analysts. For instanc...

Background: Seniors have been only little considered in studies examining problematic internet use and associated health issues, although they may present risk factors that make them particularly vulnerable for the development of problematic internet use. Objectives: (1) To compare Internet use and problematic use among seniors in Switzerland and P...

Craving is central in the prognosis of gambling disorder. The elaborated intrusion theory (EIT) provides a sound framework to account for craving in addictive disorders, and interference methods inspired from the EIT have substantiated their effectiveness in mitigating substance and food-related cravings. The principle of these methods is to recrui...

Evidence suggests that body image concerns and disordered eating exist in women even at older ages. Few studies have examined the factors that are related with body image and eating concerns in this age group. In particular, the roles of sociocultural influences and thin-ideal internalization remain unclear. In the present study, we tested a modifi...

Purpose The present study explored the potential factors associated with disordered eating behaviors and attitudes in older women. Methods Women aged 60–75 years were recruited in the community (n = 203) and completed questionnaires. The Eating Disorder Examination-Questionnaire (EDE-Q) was used to evaluate disordered eating behaviors and attitude...

Alcohol use disorder (AUD) is frequently comorbid with other psychiatric disorders. However, few studies investigated the psychometric properties of AUD screening tools in presence of co-occurring disorders. This study examined the diagnostic accuracy of a short AUD screening tool among young adults, in the presence of high vs. low or moderate symp...

Objectives We aimed to develop the transaddiction craving triggers questionnaire (TCTQ), which assesses the propensity of specific situations and contexts to trigger craving and to test its psychometric properties in alcohol use disorder (AUD). Methods This study included a sample of 111 AUD outpatients. We performed exploratory factor analysis (E...

Background and aims: Short screenings for alcohol use disorder (AUD) are crucial for public health purposes, but current self-reported measures have several pitfalls and may be unreliable. The main aim of our study was to provide empirical evidence on the psychometric performance of self-reports currently used. Our research questions were: compare...

Background and aims: Cybersex is increasingly associated with concerns about compulsive use. The aim of this study was to assess the roles of motives and sexual desire in the compulsive use of cybersex. Methods: The sample consisted of 306 cybersex users (150 men and 156 women). The participants were assessed using the Compulsive Internet Use Sc...

Both research and clinical practice acknowledge the importance of craving as a maintenance and relapse factor in gambling disorder. The elaborated intrusion theory (EIT; Kavanagh et al., 2005) of desire has been extensively investigated in relation to psychoactive substance or food cravings but, to date, has scarcely been studied in relation to gam...

About possible contributors and new perspectives to addictive use of cybersex The term « cybersex » refers to the use of the Internet for sexual purposes (pornography, webcams, dating). While moderate use of cybersex could have a positive effect on sexual life, a small fraction of these cyber-users could have difficulties to control their consumpti...

The term « cybersex » refers to the use of the Internet for sexual purposes (pornography, webcams, dating). While moderate use of cybersex could have a positive effect on sexual life, a small fraction of these cyber-users could have difficulties to control their consumption with negative consequences. This phenomenon, whose understanding of the mec...

This PDF contains the complete CISBA in its original French version. There is currently no English version. Any interested person can propose to make a translation. If you plan to use this inventory, feel free to adapt, update or complete it.There is no cut-off score or official composite score, this inventory aims to have a fairly broad overview o...

The use of social network sites (SNSs) has grown dramatically. Numerous studies have shown that SNS users may suffer from excessive use, associated with addictive-like symptoms. With a focus on the popular SNS Facebook (FB), our aims in the current study were twofold: First, to explore the heterogeneity of FB usage and determine which kind of FB ac...

Background and aims: The Internet is widely used for sexual activities and pornography. Little is known, however, about why people look for meetings and sexual interactions through the Internet and about the correlates of cybersex addiction. The goal of this study was to construct a questionnaire for cybersex motives [Cybersex Motives Questionnair...

Background: Dual diagnosis is common in Borderline Personality Disorder (BPD), one of the most common being Substance Use Disorder (SUD). Previous studies have shown that general psychiatric management (GPM) was effective in reducing borderline symptoms. In the present study, we tested whether the short GPM was as effective in the BPD + SUD as in...

Background: An increasing number of studies are concerned with various aspects of cybersex addiction, the difficulty some persons have in limiting cybersex use despite a negative impact on everyday life. Objective: The aim of this study was to assess potential links between the outcome variable cybersex addiction, assessed with the Compulsive In...

BACKGROUND An increasing number of studies are concerned with various aspects of cybersex addiction, the difficulty some persons have in limiting cybersex use despite a negative impact on everyday life. OBJECTIVE The aim of this study was to assess potential links between the outcome variable cybersex addiction, assessed with the Compulsive Intern...

Cette comédie dramatique américaine montre la perception de l’autisme dans les années 80. Le plus grand succès de Barry Levinson est un film précurseur sur le thème de l’autisme. Cependant, il met plutôt en avant une image stéréotypée de ce trouble. www.sanp.ch/online-onlycontent

Background and aims The DSM-5 includes criteria for diagnosing Internet gaming disorder (IGD) that are adapted from substance abuse and widely used in research and clinical contexts, although evidence supporting their validity remains scarce. This study compared online gamers who do or do not endorse IGD criteria regarding self-control-related abil...

Impulsivity is a multifaceted construct playing an important role in the development and maintenance of substance use disorders (SUD). The Short French UPPS-P consists of a 20-item scale measuring five impulsivity components: negative urgency, positive urgency, lack of premeditation, lack of perseverance, and sensation seeking. The aim of the prese...

Online gambling has gained popularity in the last decade, leading to an important shift in how consumers engage in gambling and in the factors related to problem gambling and prevention. Indebtedness and loneliness have previously been associated with problem gambling. The current study aimed to characterize online gamblers in relation to indebtedn...

Background: Dysfunctional cognitions regarding weight and shape and their implications for self-esteem are considered core features of anorexia nervosa and bulimia nervosa. However, they have also been associated with the severity of binge eating disorder (BED). Therefore, they should be screened with appropriate instruments to tailor treatment to...

Silver Linings Playbook («Happiness Therapy») est un film du genre comédie dramatique, réalisé en 2012 par David O. Russell. Il s'agit de l'adaptation du livre du même nom de Matthew Quick. Après avoir passé plusieurs mois au sein d'un hôpital psychiatrique dans lequel il a été interné suite à la violente agression envers l'amant de son épouse Nikk...

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Video games are widely practiced. Questions about their potential health risks arise, including the risk of addiction. If there is at present no official diagnosis of video games addiction, the DSM-5 proposes temporary criteria based on pathological gambling. Video game addiction affects a minority of at risk individuals. The proposed treatments ar...

Background The 7-item Game Addiction Scale (GAS) is a used to screen for addictive game use. Both cross cross-linguistic validation and validation in French and German is needed in adult samples. The objective of the study is to assess the factorial structure of the French and German versions of the GAS among adults. Methods Two samples of men from...

Background: It has been shown that religious beliefs and affiliations might be a protective factor for trying or using drugs. Objectives: This study focuses on whether the choice to try a specific drug is also influenced by religion. The data were collected in the Cohort Study on Substance Use Risk Factors (C-SURF), a longitudinal study designed to...

Background and aims: Video gaming addiction or problematic game use are heterogeneous concepts. Players differ widely in their involvement in games in terms of motivations and consequences. World of Warcraft (WoW) is one of the most played massive multiplayer online role playing games and characterization of Wow players involvement in the game is m...

Background and aims: Facebook is the most used online social networking service. Previous studies have assessed a potential addictive use of Facebook, but so far none of those papers, to our knowledge, described precisely what people are actually doing on this service (e.g., video-games, friends-relatives monitoring, etc.), and the risk factors ass...

Background and aims: The prevalence of Internet gamblingis increasing. However, little information is available ongamblers’ characteristics and risk factors for problemgambling. The current study aims to identify Internetgambler subgroups. Methods: Data was collected from 584 participants recruited online on gambling websites and forums. Participan...

Background and aims: Dichotomizing a questionnaire is a frequent habit in the scientific literature as well as in clinical practice. It has been advocates for about 30 years that this method should be avoided. Therefore, the presentation will attempt to show from a clinical, an epidemiological and a statistical point of view that dichotomizing a qu...

Despite the absence of adequate scientific evidence, disulfiram has been prescribed for decades and is still largely advocated. As the arguments sustaining its use cannot be evidence based, they have to be founded on other properties in order to be effective. The present paper reviews different forms of fallacies used to sustain disulfiram’s effica...

Background: Attitudes toward body shape and food play a role in the development and maintenance of dysfunctional eating behaviors. Nevertheless, they are rarely investigated together. Therefore, this study aimed to explore the interrelationships between implicitly assessed attitudes toward body shape and food and to investigate the moderating effec...

Background: The Internet Addiction Test (IAT) is the most widely used questionnaire to screen for problematic Internet use.Nevertheless, its factorial structure is still debated, which complicates comparisons among existing studies. Most previous studies were performed with students or community samples despite the probability of there being more p...

While addictions to substances such as alcohol, tobacco, and other drugs have been extensively investigated, interest has been growing in potential non-substance-related addictive behaviors (e.g., excessive gambling, buying or playing video games). In the current study, we sought to determine the prevalence and characteristics of a wide range of ad...

Background and aims: Evidence on the representativeness of self-selected samples in online surveys is lacking. Current study aims to test the representativeness of a self-selected sample of online gamers. More precisely, this study com - pares the characteristics of two samples of self-selected ava - tars with a randomly selected sample of avatars....

Background and aims: Harm reduction has been developed primary for drug use and addiction. Its definition according to the international harm reduction association is: “It refers to policies, programmes and practices that aim to reduce the harms associated with the use of psychoactive drugs in peo - ple unable or unwilling to stop”. When it comes t...

Background: The use of the family history method is recommended in family studies as a type of proxy interview of non-participating relatives. However, using different sources of information can result in bias as direct interviews may provide a higher likelihood of assigning diagnoses than family history reports. The aims of the present study were...

In WHO Meeting report Public Health Implications of Excessive Use of the Internet, Computers, Smartphones and Similar Electronic Devices http://apps.who.int/iris/bitstream/10665/184264/1/9789241509367_eng.pdf

ntroduction Homosexuality and bisexuality have been associated to increased risks of substance use. Affiliation with the gay culture is one of the explanatory models. According to this model, homosexual persons should, compared to heterosexual persons, preferentially use (or at least try) substances which are usual within the gay scene. Objectives...

Introduction Substance abuse by young people remains one of the most widespread and costly problems in Europe. Some previous studies reported an association between sexual orientation and substance use whereas it is assumed that religiosity could be a protective factor regarding substance use. Objectives To better understand the relationship betw...

Chemical and behavioral addictions are highly prevalent in our societies. Nevertheless, studies investigating a large panel of addictive behaviors in a community sample are lacking from the current literature on the topic. The aim of the current study is to explore addictive behaviors prevalence, characteristics, and interrelations in a sample of F...

Behavioral addictions (gambling, gaming, internet use) are new challenges for policy makers, and the question arises if harm reduction is an applicable concept. Gambling addiction policies are trying to include harm reduction models (limitation of the amount of money you can bet, limitation in access to gambling venues). We will discuss if these mo...

Disulfiram's use is not supported by scientific evidence but nevertheless largely advocated and used. This would be less odd in case of lacking or just preliminary evidence. What is peculiar in the case of disulfiram's prescription is its persistence against evidence. Hence arise the question how it is possible that its use can be supported, i.e. b...

Background: The number of medical studies performed through online surveys has increased dramatically in recent years. Despite their numerous advantages (eg, sample size, facilitated access to individuals presenting stigmatizing issues), selection bias may exist in online surveys. However, evidence on the representativeness of self-selected sample...

To assess (1) the lifetime prevalence of exposure both to trauma and post-traumatic stress disorder (PTSD); (2) the risk of PTSD by type of trauma; and (3) the determinants of the development of PTSD in the community. The Diagnostic Interview for Genetic Studies was administered to a random sample of an urban area (N = 3,691). (1) The lifetime prev...

Objective The aims of the present study were to assess the associations between mood, anxiety and substance use disorders, including their subtypes, and the prevalence of cardiovascular risk factors (CVRFs). Method Thorough physical investigations, biological measures and standardized interview techniques were used to assess 3716 subjects of an urb...

There is limited information on the specificity of associations between parental bipolar disorder (BPD) and major depressive disorder (MDD) and the risk of psychopathology in offspring. The chief aim of the present study was to investigate the association between mood disorder subtypes in the two parents and mental disorders in the offspring. A tot...

To assess the specific effect of alcohol dependence (AD) or heroin dependence (HD) in patients and their spouses on the risk of psychopathology in their 276 6.0- to 17.9- year-old children (mean 11.3 years). The sample included 101 offspring of patients with AD, 23 of patients with HD, and 152 of medical controls, as well as their 2 parents. Partic...

Few studies have assessed whether offspring resemble their parents regarding Behavioral Inhibition (BI) and whether inhibition is associated with parenting attitudes. The goals of the present paper were 1) to establish the associations between retrospectively assessed childhood BI features in parents and current reports of BI in their 12 year-old o...