Sriram Iyengar

University of Arizona College of Medicine Phoenix · Medicine

Background Persuasive technology is an umbrella term that encompasses software (eg, mobile apps) or hardware (eg, smartwatches) designed to influence users to perform preferable behavior once or on a long-term basis. Considering the ubiquitous nature of mobile devices across all socioeconomic groups, user behavior modification thrives under the per...

Background As a major public health crisis, the novel coronavirus disease 2019 (COVID-19) pandemic demonstrates the urgent need for safe, effective, and evidence-based implementations of digital health. The urgency stems from the frequent tendency to focus attention on seemingly high promising digital health interventions despite being poorly valid...

Objectives: Telehealth implementation is a complex systems-based endeavour. This paper compares telehealth responses to (COrona VIrus Disease 2019) COVID-19 across ten countries to identify lessons learned about the complexity of telehealth during critical response such as in response to a global pandemic. Our overall objective is to develop a heal...

In this extensive review of behavioral digital obesity interventions, we reviewed randomized control trials aimed at weight loss or maintaining weight loss and identifying persuasive categories and principles that drive these interventions. The following databases were searched for long-term obesity interventions: Medline, PsycINFO, Academic Search...

Background: In Fiji and other South Pacific island countries, depression and suicide are of great concern. There is a pressing need to rapidly identify those at risk and provide treatment as soon as possible. Objective: Design, develop and test a mobile health tool that enables CHNs to easily and rapidly identify individuals at risk for suicide...

Background: Although there is a rise in the use of mobile health (mHealth) tools to support chronic disease management, evidence derived from theory-driven design is lacking. Objective: The objective of this study was to determine the impact of an mHealth app that incorporated theory-driven trigger messages. These messages took different forms fol...

BACKGROUND While the use of mHealth tools to support chronic disease management is on the rise, there is still lack of evidence on theory-driven mHealth interventions, particularly utilizing different types of behavioral trigger messages based on the Fogg Behavior Model. OBJECTIVE The objective of our study was to determine the impact of the mHeal...

Objectives Spouses and partners of individuals with bipolar disorder (BD) experience significant burden. As there are some limitations to standard psychosocial caregiver interventions, mobile health technology (mHealth) may be a way to reduce burden and improve well-being in these caregivers. The purpose of this study was to explore how the well-be...

RESUMO Introdução: A dor é um problema se saúde pública mundial, sendo que as lacunas no processo de ensino e aprendizagem sobre a avaliação da dor contribuem para esta situação. O desenvolvimento de estratégias inovadoras para o ensino-aprendizagem, como objetos virtuais de aprendizagem, pode colaborar para melhoraria do cuidado de pacientes com...

Background: Patient safety is a fundamental component of high-quality delivery of health care. However, despite scientific advances, surgical patients continue to face risks. Among the most common complications in surgery are operations on the wrong patient, performance of the wrong procedure or operation on the wrong surgical site, lack of adequa...

Introdução: A dor é um problema se saúde pública mundial, sendo que as lacunas no processo de ensino e aprendizagem sobre a avaliação da dor contribuem para esta situação. O desenvolvimento de estratégias inovadoras para o ensino-aprendizagem, como objetos virtuais de aprendizagem, pode colaborar para melhoraria do cuidado de pacientes com dor, sen...

Introduction: The increasing use of Health Information Technology (HIT) can add substantially to workload on clinical providers. Current methods for assessing workload do not take into account the nature of clinical cases and the use of HIT tools while solving them. Methods: The Clinical Case Demand Index (CCDI), consisting of a summary score and v...

Problem definition: Diagnostic errors annually affect at least 5% of adults in the outpatient setting in the United States. Formal analytic techniques are only infrequently used to understand them, in part because of the complexity of diagnostic processes and clinical work flows involved. In this article, diagnostic errors were modeled using fault...

Background: Severe mental illnesses (SMIs) have been found to be associated with both increases in morbidity-mortality, need for treatment care in patients themselves, and burden for relatives as caregivers. A growing number of web-based and mobile software applications have appeared that aim to address various barriers with respect to access to c...

With the rapid emergence of mobile technologies in recent years, mobile health (m-health) has become fundamental to healthcare. Persuasion strategies and behavior change support features are widely used in m-health applications to increase the effectiveness of these applications on users. However, in the literature, there is a lack of research to a...

Recent changes in health information technology have dramatically altered the face, delivery, and management of healthcare particularly as it relates to mHealth. With increases in smart phone ownership, mHealth potentially has the ability to provide far-reaching transformation of chronic disease management particularly when aligned with behavioral...

In recent years, the presence or absence of behavior change techniques used in mobile applications for physical activity have been investigated by several authors in the context of content analysis and qualitative studies. However, users’ adoption and evaluation of application specific features remains to be an unexplored area. In this study, mobil...

Development and electronic distribution of Clinical Practice Guidelines production is costly and challenging. This poster presents a rapid method to represent existing guidelines in auditable, computer executable multimedia format. We used a technology that enables a small number of clinicians to, in a short period of time, develop a substantial am...

Background: Thousands of patients seek health services every day with complaints of pain. However, adequate pain assessment is still flawed, a fact that is partly related to gaps in professional learning on this topic. Innovative strategies such as the use of a virtual learning object mediated by persuasive technology in the learning of undergradu...

Mobile devices, as persuasive technologies, represent an important platform to promote changes in attitudes and behaviors. They are not only understood as tools, but as a learning process that provides different opportunities to learn how to learn. The objectives of the study were to measure the quality of a virtual mobile learning object, to measu...

Mobile devices, as persuasive technologies, represent an important platform to promote changes in attitudes and behaviors. They are not only understood as tools, but as a learning process that provides different opportunities to learn how to learn. The objectives of the study were to measure the quality of a virtual mobile learning object, to measu...

Background The inclusion of new technologies in education has motivated the development of studies on mental workload. These technologies are now being used in the teaching and learning process. The analysis enables identification of factors intervening in this workload as well as planning of overload prevention for educational activities using the...

Unlabelled: Studies show that current modes of psychoeducation (PE) cannot be availed of by a substantial population of those in need. Mobile health technologies have great potential to serve such populations. However converting PE to mobile platforms is challenging. We present a methodology for this purpose based on existing learning styles theor...

The objective of our study was to evaluate usefulness and effectiveness of Human Centered GeoVis prototype”The SanaViz” against a conventional GeoVis application Instant Atlas. The SanaViz is an interactive, internet based application aimed at facilitating visual exploration of public health data, and in this context telehealth data from Brazil. A...

Social media is an interesting, relatively new topic in health and self-management, which is generating enormous amounts of data, but little is yet known about its effect on the health of participants. The goal of this study is to determine online interaction behaviours that predict weight loss performance. The problem is modelled as a binomial cla...

There are few tried and tested mobile technology applications to enhance and standardize the quality of health care by frontline rural health providers in low-resource settings. We developed a media-rich, mobile phone-based clinical guidance system for management of fevers, diarrhoeas and respiratory problems by rural health providers. Using a rand...

Standardization of second opinion question-answer pairs with a classification system can be used to facilitate data sharing and reuse. The Brazilian telehealth program faces the problem of representing biomedical knowledge from the primary care second opinion demands generated by rural health care teams. The objective is to determine if one of the...

Currently, in developing countries, there is considerable interest in using mobile phones as job-aids for community health workers (CHWs) to improve the care they provide. However, acceptance of new technologies can be inhibited if the workload imposed is perceived as excessive compared to existing methods. To compare perceived workload of CHWs usi...

Motivation: Although trauma is the leading cause of death for those below 45years of age, there is a dearth of information about the temporal behavior of the underlying biological mechanisms in those who survive the initial trauma only to later suffer from syndromes such as multiple organ failure. Levels of serum cytokines potentially affect the c...

Efficient allocation of medical resources for spaceflight is important for crew health. The Integrated Medical Model (IMM) was developed to estimate medical event occurrences, mitigation, and resource requirements. An optimization module was created for IMM that uses a systematic process of elimination and preservation to maximize crew health outco...

Today, there is an ever-increasing amount of biological and clinical data available that could be used to enhance a systems-based understanding of disease progression through innovative computational analysis. In this article, we review a selection of published research regarding computational methods, primarily from systems biology, which support...

In the current explosion of internet technologies and exponentially increasing usage of the web there exists a need for effective searching and retrieval of information and resources. This is particularly true in medical and health care education. In the mEducator EUC funded project (www.mEducator.net), the collbaorators are attempting to develop t...

Objectives: Crosstalk relates to how the molecular interactions in biological pathways determine functional specificity, how ubiquitous messengers transmit specific information, and how redundant messages crosslink within the system while undesired signals are minimized. Objective, quantitative measures of crosstalk can yield useful insights into u...

Background: As the volume of biomedical text increases exponentially, automatic indexing becomes increasingly important. However, existing approaches do not distinguish central (or core) concepts from concepts that were mentioned in passing. We focus on the problem of indexing MEDLINE records, a process that is currently performed by highly traine...

To study and analyze the possible benefits on performance of community health workers using point-of-care clinical guidelines implemented as interactive rich media job aids on small-format mobile platforms. A crossover study with one intervention (rich media job aids) and one control (traditional job aids), two periods, with 50 community health wor...

Interoperability is a requirement of recent electronic health record (EHR) adoption incentive programs in the United States. One approved structure for clinical data exchange is the continuity of care document (CCD). While primarily designed to promote communication between providers during care transitions, coded data in the CCD can be re-used to...

Shock is a prime inciting event for postinjury multiple organ failure (MOF), believed to induce a state of injurious systemic inflammation. In animal models of hemorrhagic shock, early (< 24 hours) changes in cytokine production are an index of the systemic inflammatory response syndrome. However, their predictive value in trauma patients remains t...

The Medical Algorithms Project, a web-based resource located at www.medal.org, is the world's largest collection of medical-related spreadsheets, consisting of over 13,500 Excel spreadsheets each encoding a medical algorithm from 45 different areas of medical practice. This free resource is in use worldwide with over 106,000 registered users as of...

Information overload is a problem for users of MEDLINE, the database of biomedical literature that indexes over 17 million articles. Various techniques have been developed to retrieve high quality or important articles. Some techniques rely on using the number of citations as a measurement of an article's importance. Unfortunately, citation informa...

Persuasive technologies for healthcare have great potential to beneficially impact the well-being of individuals with chronic disease, support self-care, and encourage adherence to correct treatment guidelines by non-physician care providers such as medics and community health workers. However healthcare poses special challenges with respect to des...

Currently, paper-based and/or electronic together with telecommunications links to Earth-based physicians are used to assist astronaut crews perform diagnosis and treatment of medical conditions during space travel. However, these have limitations, especially during long duration missions in which telecommunications to earth-based physicians can be...

INTRODUCTION: We demonstrated that critically injured trauma patients who develop MOF display differences in cytokine expression. Consensus is lacking on the predictive value of individual cytokines. We hypothesize that cytokine profiling can be used as a diagnostic tool for predicting MOF in trauma patients. METHODS: A prospective observational st...

Diagnostic tests are characterized by multiple performance measures whose complex mutual interactions are difficult for medical and nursing students to understand. We describe VITA (visual and interactive test analysis), an interactive multi-dimensional visualization system designed to display the intricate, non-linear relationships between these m...

Objectives: In multiple organ failure (MOF) post-trauma organs remote from injury location, including liver, heart, lungs, and kidneys, cease functioning. Pro and anti-inflammatory cytokines are implicated as signaling messengers in this process; their signaling pathways differ between MOF and non-MOF (NMOF) patients during the first 24 hours follo...

Objectives: During development of a method to identify biological signaling pathways implicated in multiple organ failure, we expected that the qualitative results of the molecular pathway analysis would be independent of the numerical units used. Methods: We analyzed BioRad immunoassay data for eleven serum cytokines from 48 patients sustaining ma...

Multiple organ failure (MOF) is the leading cause of in-hospital mortality in critically injured trauma patients (Ciesla et al, 2005). In this setting, organs remote from injury location, including liver, heart, lungs, and kidneys, cease functioning. Pro and anti-inflammatory cytokines are implicated as signaling messengers in this process (Moore e...

The Morphoproteomics paradigm in cancer research views tumorigenesis as a consequence of multifactorial interactions of genetics, cell cycle, signaling pathways, intracellular venues of specific protein-protein interactions, and others. Two important strategies for taming complexity are Abstraction: capturing the essential attributes of domain know...

Predictive modeling in biology is difficult because a) randomness is ubiquitous, and b) biological processes are profoundly complex, containing hundreds or thousands of component interactions. The latter leads to uncertainty, i.e., precise data about probabilities, pathway structure, rate constants, and parameters governing biochemical reactions ar...

The biological cell, a natural self-contained unit of prime biological importance, is an enormously complex machine that can be understood at many levels. A higher-level perspective of the entire cell requires integration of various features into coherent, biologically meaningful descriptions. There are some efforts to model cells based on their ge...

Databases continue to grow but the metrics available to evaluate information retrieval systems have not changed. Large collections such as MEDLINE and the World Wide Web contain many relevant documents for common queries. Ranking is therefore increasingly important and successful information retrieval systems, such as Google, have emphasized rankin...

Biological signaling networks comprise the chemical processes by which cells detect and respond to changes in their environment. Such networks have been implicated in the regulation of important cellular activities, including cellular reproduction, mobility, and death. Though technological and scientific advances have facilitated the rapid accumula...

Distributed computing systems consist of computers interconnected by communications links. In such systems, Load sharing is an important technique used to improve system performance in which jobs are transferred from overloaded nodes to underloaded ones. However, due to the ubiquitous and inescapable presence of network latencies, various pitfalls...

An abstract is not available.

GuideView is a system designed for structured, multi-modal delivery of clinical guidelines. Clinical instructions are presented simultaneously in voice, text, pictures or video or animations. Users navigate using mouse-clicks and voice commands. An evaluation study performed at a medical simulation laboratory found that voice and video instructions...

Background Neuroscience is experiencing explosive growth in detailed high-quality experimental information on neural processes underlying learning, memory and behavior. There is a need for computational models that can manage this outpouring of information, derive knowledge from information, and to generate novel, testable hypotheses. Many current...

College science laboratory instruction is shifting from prescribed to inquiry-based labs, using mostly lab manuals developed by each college. At the same time, class sizes are increasing and most colleges report having only one instructor in the lab. This combination leaves many instructors handling largely managerial tasks as opposed to engaging s...