Sridharan Gurunagarajan

Srimad Andavan Arts and Science College (Autonomous) · Biochemistry

Coronavirus disease 2019 (COVID-19) management has been challenging for patients with comorbidities. Patients with diabetes and COVID-19, in particular, have shown severe symptoms and rapid progression of the disease. They also have a high mortality rate compared to the non-diabetic population. The high mortality rate is caused in people with diabe...

Zanthoxylum armatum DC, a medicinal plant species in India, is an exceptionally nutritious vegetable with a variety of potential uses in treating rheumatism, venomous bites, and microbial infections. In the present study, we aimed to investigated the antidiabetic and antioxidant effects of aqueous extracts of Z. armatum Stem Bark (Za-Aq) in High Fa...

In this study, the aqueous extract of Chenopodium album Linn. was examined for its antidiabetic activity using alloxan monohydrate-induced experimental rats. HPLC analysis of the extract showed substantial concentrations of polyphenols, mainly gallic acid (0.02%, w/w) and kaempferol (0.001%, w/w). In vitro studies showed profound inhibition of α-am...

Probiotics are living microbes that play a significant role in protecting the host in various ways. Gut microbiota is one of the key players in maintaining homeostasis. Cancer is considered one of the most significant causes of death worldwide. Although cancer treatment has received much attention in recent years, the number of people suffering fro...

Cancer is a multifaceted disease, the second leading cause of death in the world exemplified by uncontrolled cell growth and cell division. Plant as medicinal source have gained more research interest in recent years, particularly terpenoids like salvicine, ursolic acid from plant sources are important anti-cancerous drugs which are under clinical...

Background Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease causing severe locomotor disability and deterioration in the quality of life. Existing treatments for RA mainly focus on the use of immunomodulators and the suppression of synovial inflammation, and many have significant side effects. Medicinal plants are regarded as...

Background Obesity is a medical condition often associated with chronic diseases such as hyperlipidemia, Type 2 diabetes mellitus, colon cancer, other cardiovascular diseases etc., and is become a major health problem worldwide in recent years. The non-satisfactory long term effectiveness as well as the side effects associated with the modern pharm...

Asthma is a chronic inflammatory respiratory disease with increasing prevalence which has been linked to the interaction of genetic and environmental factors. Specific types of infections and environmental exposure, alongside a predisposed set of genes, can lead to a systemic propensity for allergic T‐helper (Th) type 2 cells to induce cytokine res...

Objectives: To analyze the microscopic, macroscopic, physicochemical, and phytochemical standards of the Zanthoxylum armatum DC. (stem bark). Methods: Pharamacognostic studies, namely macroscopic, microscopic, and powder microscopic analysis of stem bark were carried out. Physicochemical standards - ash content including total ash content, water so...

Citrus sinensis (L.) Osbeck is extensively cultivated worldwide and one of the most consumed fruits in the world. We evaluated the therapeutic properties of the methanol extract from Citrus sinensis fruit peel (CSMe) in high-fat diet-fed streptozotocin-induced insulin-resistant diabetic rats. Body weight, food intake, and water consumption were ana...

Objective: To evaluate the microscopical, physicochemical and phytochemical analysis of Gardenia jasminoides (Ellis).Methods: The leaves of Gardenia jasminoides (Ellis) was studied through macroscopic, microscopic, physicochemical standards such as moisture content, ash values, extractive values and phytochemical analysis includes preliminary scree...

Export Date: 18 October 2014

Present study, we utilized the bio-reductive potential of the Elaeagnus indica Servett for the synthesis of silver nanoparticles (AgNPs). The green synthesized AgNPs was achieved at 80°C and found to be highly stable in room temperature for a month. The AgNPs was found to be spherical in shape with an average size of ~30nm in diameter. The AgNPs we...

Present study, we utilized the bio-reductive potential of the Elaeagnus indica servett,fo the synthesis of silver nanoparticles (AgNPs). The green synthesized AgNPs was achieved at 80°C and found to be highly stable in room temperature for a month. The AgNPs was found to be spherical in shape with an average size of ~30nm in diameter. The AgNPs wer...