Spyridon Papageorgiou

University of West Attica | TEIATH · Biomedical Sciences

This study introduces a novel, robust, and efficient method for the simultaneous quantitative determination of three sunscreen filters, namely, 4-methylbenzylidene camphor, octyl methoxycinnamate, and avobenzone, in a moisturizing sunscreen cream specifically designed for acne-prone skin. The method employs high-performance liquid chromatography wi...

This study introduces a novel, robust, and efficient method for the simultaneous quantitative determination of three sunscreen filters namely 4-methylbenzylidene camphor, octyl methoxycinnamate, and avobenzone, in a moisturizing sunscreen cream specifically designed for acne-prone skin. The method employs high performance liquid chromatography with...

Patients with diabetes, the elderly, and those who have certain inherited conditions are particularly vulnerable to atypical wound healing with lingering repercussions. Remarkably, the current remedies are insufficient since, despite the plethora of wound healing options, only limited efficacy is observed. This review is a bibliographic survey on e...

With the increase in interest for natural innovative skin care products, an effort was made in our laboratory to study the beneficial effects of cannabinoids and prebiotics/probiotics on the skin. Through efficacy studies, the contribution of the specific active substances to improving the health and appearance of the skin was investigated. The pre...

The aim of the present experimental study is the incorporation of an extract of the Porphyra Umbilicalis seaweed, which contains mycosporin derivatives (MAAs) in a sunscreen formulation, in combination with organic filters, in order to study its influence on the SPF and UVA PF. The results obtained from the in vitro SPF and UVA PF measurements as w...

Hyaluronic acid (HA) is a natural component of the body and especially of the skin, which exerts an important role in its hydration, regeneration and healing process. HA has shown a wide range of pharmacological activities such as antiinflammatory, immunomodulatory, antitumor, antidiabetic, antiaging and skin repair. Moreover, HA contributes in reg...

The aim of this research was to evaluate the abrasive dentin wear that can be induced by three commercial whitening toothpastes following a tooth-brushing simulation (TBS) corresponding to a three-month period. Sixty human canines were selected, and the roots were separated from the crowns. Then the roots were randomly divided into six groups (n =...

Sunscreen use has increased in recent years, as sunscreen products minimize the damaging effects of solar radiation. Active ingredients called ultraviolet (UV) filters or UV agents, either organic or inorganic, responsible for defending skin tissue against harmful UV rays, are incorporated in sunscreen formulations. UV agents have a serious impact...

A key focus in designing sunscreen products is to select a combination of ultraviolet (UV) filters that delivers the target sun protection factor (SPF) and affords broad-spectrum protection with maximum efficiency, in such a way as to minimize the overall cost and any negative skin effects. The presence of more than one UV filter can lead to synerg...

A global tendency for products considered environmentally sustainable, and ecologically obtained led the industry related to personal care formulations to fund the research and the development of personal care/cosmetics containing ingredients from natural resources. Furthermore, consumers are aware of environmental and sustainability issueans, thus...

A novel High-Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS) method was developed for the simultaneous determination of the in vitro skin permeation profile of four UV filters. The sunscreen products contained the following components: octocrylene (OC), ethylhexyl methoxycinnamate (EHMC), diethylamino hydroxybenzoyl hexyl be...

Purpose: The aim of this in vitro study was to investigate the effectiveness of a novel charcoal-containing whitening toothpaste and a mouthwash on tooth color change and the alterations of enamel that may be induced after toothbrushing, corresponding to a 90-day period. Materials and Methods: Forty human canines were used, stained with coffee, and...

Papain is a sulphydryl, proteolytic enzyme isolated from papaya latex and is readily available from a number of sources. This enzyme has been widely used in pharmaceutical, cosmetic and nutrition area. It is used in topical formulations as a debriding agent for the healing of open, extensive wounds and burnings. It is also employed as an enhancer f...

Objective: To develop and validate a simple reversed phase HPLC method for the quantitation and evaluation of stability of α-Lipoic acid in cosmetics, according to International Conference on Harmonization (ICH) Guidelines. Methods: The chromatography was performed on a reversed-phase Luna C18, analytical column (150 x 4.6 mm id, 5 μm particle s...

The high demand for cosmetic products of plant origin and the parallel development of research in cosmology to find original plant products has led to the exploration and use of cannabis ingredients. The two main components of industrial cannabis (Cannabis sativa L or cannabis) are cannabidiol (CBD) and tetrahydro-cannabinol (THC) and belong to the...

Background: Numerous oncology patients who receive targeted therapy suffer from the skin adverse effects induced. Novel agents, that is tyrosine kinase inhibitors and RAS-RAF-MEK-ERK pathway, have given good results in patient survival while decreasing the systemic toxicities in comparison to conventional cytotoxic chemotherapy, but are also relat...

A global tendency for products considered environmentally sustainable, and ecologically obtained led the industry related to personal care formulations to fund the research and the development of personal care/cosmetics containing ingredients from natural resources. Furthermore, consumers are aware of environmental and sustainability issueans, thus...

Lipoic acid (α-LPA), 1.2-dithiolane-3-pentanoic acid, is an universal antioxidant present in prokaryotic and eukaryotic cells. It acts as a cofactor in different multi-enzyme complexes. It plays an important role in the synergism of antioxidants by directly recycling vitamin C, glutathione and coenzyme Q10 and indirectly recycling vitamin E. Due to...

Sep Sci plus 2018, 1, 159–167 DOI: 10.1002/sscp.201800016 The cover picture shows a representation of the determination of oligopeptides in cosmetic creams by hydrophilic interaction liquid chromatography/electrospray ionization mass spectrometry (HILIC–ESI/MS) and it was graphically designed by Nikolas Panteris, Senior Colorist. Peptide cosmeceuti...

Peptides are a very popular category of cosmetic ingredients covering a wide range of applications in cosmetics. Hydrophilic interaction liquid chromatography is promising for the analysis and separation of such polar substances. In this work, the chromatographic behaviour of oligopeptide-20 and oligopeptide-24 was initially investigated on a zwitt...

Facial deformities are a major problem and originate either from congenital or from acquired malformations. With the term "congenital malformation" we mean the result of some protest during the formation of the fetus, which can take place between the sixth day and the end of the seventh month of pregnancy. With the term "acquired malformation" we m...

Assessment of study-level explorative factors assessed with random-effects meta-regression for the subgroup of studies that assessed 1-phase fixed appliance treatment

Results of the Egger's test for reporting bias for the primary and secondary outcome.

Meta-epidemiological assessment of matching within-studies.

Meta-epidemiological assessment of matching across-studies.

A priori eligibility criteria used in the review.

Risk of bias assessment for the included studies.

Table A in S1 File. Registry searches performed with identified hits. Table B in S1 File. List of included and excluded studies with reasons. Table C in S1 File. Differences in the time from completion to publication for the 33 published trials. (P values correspond to Kruskal-Wallis test). Table D in S1 File. Influence of protocol or trial publica...

Dataset of the current study. (XLSX)

Briefly we summarize the main adverse effects of radiation therapy in oncology patients. The ratio for radiation dermatitis and Epidermal Growth Factor Inhibitors (EGFRIs) side effects, if EGFRIs treatment is received in the same period as radiation than the case the radiation is received alone is discussed. Preventive topical techniques and pallia...

This study presents the association of different active substances in a multifunctional cosmetic formulation. A night cream containing an association of antioxidants (vitamins A, E and resveratrol oligomers), niacinamide, phyto-steroids (Soybean sterols and Dioscorea villosa root Extract, rich in diosgenin) and the collagen promoter Acetyl Tetrapep...

The aim of this study is to evaluate the antimicrobial efficacy of some alternative preservatives in combination with Phenoxyethanol in order to produce a series of safe cosmetic products for children with sensitive skin. A shampoo, a shower gel and moisturizing body milk for children with sensitive skin were formulated. We used Phenoxyethanol as t...

This article describes the development and validation of a selective high-performance liquid chromatography method that allows, after liquid-liquid extraction and pre-column derivatization reaction with quercetin, the quantification of aluminium chlorohydrate in antiperspirant creams. Chromatographic separation was achieved on an XTerra MS C18 anal...

Effect of sea mud compresses from Messolonghi lagoon as a treatment for cellulite

Preparation of a stable and safe gel with a combination of herbal ingredients and celllose for the treatment of unpleasant symptoms in the development of the first tooth in infants

Oligopeptide-20 is a growth-factor mimicking peptide used in cosmeceuticals. This article describes the development and validation of an ion-pair reversed-phase liquid chromatography method that allows, after liquid-liquid extraction, the quantification of oligopeptide-20 in cosmetic creams. Chromatographic separation was achieved on a cyanopropyl...

In this article the beneficial effects for human health of clay minerals is studied. Minerals have been used for medical purposes since Prehistory. The use of medicinal earths in Mesopotamia, Ancient Egypt and Ancient Greece has also been proven. Clay minerals are widely used in spas. They are mixed with water (geotherapy), mixed with sea or salt...

Background: Oligopeptide-20 acts as positive regulator of cell proliferation and increases collagen and hyaluronic acid levels in keratinocyte and fibroblast cultures. Methods: After randomization half the face of twenty volunteers was treated twice daily for two months with the oligopeptide-20 cream (0.003% w/w, 300 ppm) and the other half with th...

In this article the beneficial effects for human health of clay minerals is studied. Minerals have been used for medical purposes since Prehistory. The use of medicinal earths in Mesopotamia, Ancient Egypt and Ancient Greece has also been proven. Clay minerals are widely used in spas. They are mixed with water (geotherapy), mixed with sea or salt l...

Tyrosinase is an oxidase, which catalyzes melanogenesis and is responsible for enzymatic browning in damaged fruits. Neither hyperpigmentation in human skin nor enzymatic browning infruits are desirable. This article surveys tyrosinase inhibitors newly discovered from natural and synthetic sources, for use in foods and cosmetics.

pp. 107–123 This work was partially presented at the 7th Joint Meeting of AFRP, ASP, GA, PSE and SIF, Athens, Greece, and at the XIIIth COSMODERM Joint Meeting of ESCAD and the Hellenic Society of Dermatology and Venerology, Athens, Greece. In recent years, there is a considerable interest in the development of preservative‐free or self‐preserving...

Synopsis Preservatives are added to products for two reasons: first, to prevent microbial spoilage and therefore to prolong the shelf life of the product; second, to protect the consumer from a potential infection. Although chemical preservatives prevent microbial growth, their safety is questioned by a growing segment of consumers. Therefore, ther...

Since many questions have arisen regarding the safety of the chemical/ traditional preservatives, there has been a growing interest in the development of self-preserving or preservative-free cosmetic formulations. In self-preserving formulations chemical/traditional preservatives have been replaced by other cosmetic ingredients with anti-microbial...

Among the retinoids, which are important in modern therapy for dermatological treatment of wrinkled skin, retinol and retinyl palmitate are regarded desirable because of their lower irritating activity compared to retinoic acid. Since retinol is unstable in cosmetic preparations, retinyl palmitate and liposomal retinol are used to a great extent in...