Soumya Sachdeva

Soumya Sachdeva
Atal Bihari Vajpayee Institute of Medical Sciences (ABVIMS) and Dr. Ram Manohar Lohia Hospital · Dermatology

Doctor of Medicine
MBBS, MD (DVL), DNB, ECFMG (USA).

About

32
Publications
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63
Citations
Introduction
Dermatologist. Blogger. Poet. ECFMG Certified physician
Skills and Expertise

Publications

Publications (32)
Article
Type 1 lepra reaction (T1R) is a major complication seen in nonpolar forms of leprosy and leads to significant morbidity. The classification of T1R as up and downgrading, based on previously defined histopathological criteria (by Ridley), has therapeutic and prognostic implications. The trigger factors for these reactions are poorly described, espe...
Article
Glucocorticoids are arguably the most widely used and misused drug in dermatology. There have been recent updates in its mode of action which can impact on its judicious use. There is need to use the correct steroid preparation to maximise results and minimise side effects. We present an updated review on glucocorticoids focusing on its mode of act...
Article
Full-text available
Purpose Second wave of COVID-19 pandemic was associated with an unprecedented rise in cases of mucormycosis, treatment of which has been challenging owing to the availability and side effects associated with amphotericin. Methods All patients presenting with rhino-orbital cerebral mucormycosis (ROCM) following COVID-19 infection between April 2021...
Article
Psoriatic involvement of nails manifests in the form of irregular, deep and large pits, splinter hemorrhages, subungual hyperkeratosis, oil drop spot, and onycholysis of the nail bed. Retinoids are one of the treatment modalities for nail psoriasis. Pseudogynecomastia is an uncommonly reported side effect of retinoids. We hereby describe an 11-year...
Article
Erythema nodosum leprosum (ENL), or type 2 lepra reaction, presents with crops of evanescent, tender erythematous nodules accompanied by fever, arthralgia, weight loss, malaise, and organ-specific manifestations, and is seen in borderline and lepromatous leprosy. The drugs approved for ENL include nonsteroidal anti-inflammatory drugs, systemic ster...
Article
Type 2 lepra reaction (or erythema nodosum leprosum [ENL]) is an immune complex-mediated reaction which has been reported to occur for up to 8 years after successful completion of multibacillary multidrug therapy. The management of ENL is a challenge with the patient often becoming steroid dependent; predisposing to recurrent episodes in 39%–77% of...
Article
Background While a plethora of literature continues to be published on the role of nutritional agents both in lay press and indexed journals, the data is not on a firm footing and leaves the dermatologist in a quandry and the patient confused. The various agents include vitamins, minerals, amino acids, antioxidants, diets & gluten. A proper knowled...
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Full-text available
Orofacial granulomatosis (OFG) is a rare disorder with varied etiological, immunological and infectious mechanisms playing a role and is believed to be a umbrella term which includes Melkersson Rosethal syndrome (MRS). We describe a 17 year old female who was diagnosed with OFG and was successfully treated with a combination of minocycline and clof...
Article
We read with interest and alarm the study of voriconazole ‐ a reserve drug for deep and systemic mycoses‐ in dermatophytoses and would like to caution and revise the principles that enshrine antifungal usage in dermatophytoses. It is pertinent to note that there are established tenets for administering an oral antifungal for dermatophytoses which m...
Article
Oxidative stress(OS) has been implicated as one of the etiologies in the multifactorial etiopathogenesis of alopecia areata (AA). But with the existing data, it is unclear whether oxidative stress is a cause or effect of the disease state in Alopecia areata. Aim To measure the oxidative stress parameters viz .malon-di-aldehyde(MDA),superoxide dism...
Article
Acute generalized exanthematous pustulosis is a severe, life-threatening, drug-induced cutaneous eruption that is associated with appearance of non-follicular sterile pustules on an erythematous base usually with oedema. We report a case of acute generalized exanthematous pustulosis induced by ofloxacin given for acute diarrhea. The patient was the...
Article
Colchicine is an anti-inflammatory agent which has been used for decades in the treatment of gout. The drug has a number of dermatological indications like Psoriasis, Sweet's syndrome, aphthosis, Behcet's disease, erythema nodosum, leukocytoclastic vasculitis and is consistently effective in neutrophilic disorders. Thought it is an affordable with...
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Full-text available
Psoriasis vulgaris is a chronic inflammatory disorder that affects the skin and joints. Mild disease is treated with topical corticosteroids (CS) which forms the first line of treatment for localized disease. While it is well established that prolonged use of oral or parenteral corticosteroids can lead to iatrogenic Cushing's Syndrome and suppressi...
Article
Hydroxychloroquine is one of the most frequently used drugs in dermatology with a wide variety of uses due to its immunomodulatory, anti-inflammatory, photoprotective, and metabolic actions and low side effect profile. Demonstration of its antiviral action in vitro has led to renewed interest by physicians worldwide during the ongoing coronavirus d...
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Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are adverse cutaneous drug reaction that has been associated with various drugs like antibiotics, anticonvulsant and non-steroidal anti-inflammatory agents. Fluconazole has rarely been associated with SJS and TEN. A 39-year-old male patient of SJS due to fluconazole, who was subseq...
Article
A 46 year old Jamaican man was seen in the ED with a history of subjective fever and productive cough, followed by confusion, hallucinations and slurred speech. His examination revealed decreased breath sounds over the left chest and rhonchi were present. Labs revealed neutropenia, hyponatremia, transaminitis, increased creatinine. X ray revealed l...
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Substance abuse has been defined as the use of chemical substances for non medical purposes in order to achieve alterations in psychological functioning. The substances commonly abused in India include nicotine, alcohol, cannabis and opioids. However, the use of solvents and propellants is also on the rise as these are inexpensive, legally availabl...
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Heart disease today is a major cause of morbidity and mortality plaguing mankind worldwide. The present research was undertaken to ascertain global research trends in clinical trials in Cardiology involving human subjects over the last two decades. Cross-sectional study. A detailed search strategy was employed in December 2013, using the PubMed dat...
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A 13-year-old female child presented with bilateral proptosis and subconjuctival hemorrhage of 2 months duration. Subsequently, the biopsy and peripheral smears confirmed the diagnosis of acute myeloid leukemia (AML). Recurrent cytogenetic translocation t(8:21) in AML associated with extramedullary manifestation; was discovered which is a rare even...
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Langerhans cell histiocytosis (LCH) is a disorder associated with proliferation of Langerhans cells in various organs. LCH secondary to multisystem involvement can present in a variety of ways. Because of its infiltrative nature, LCH can involve the skin, lymph nodes, the lung or the liver. Jaundice in LCH is a manifestation of liver disease; bilia...
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Full-text available
Nasal encephalocele are rare congenital anomalies; these benign masses may be confused with nasal dermoids, hemangiomas, nasal gliomas and anterior skull base masses. These lesions have concomitant defects in the anterior cranial fossa thus this potential communication can cause recurrent episodes of meningitis and/or difficulty in breathing and co...
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Full-text available
Dialysis is initiated in a patient with End stage renal disease. The recent guidelines suggest the initiation of dialysis when symptoms and signs of kidney failure are present and not merely a decrease in GFR. The most common complication postdialysis is the occurrence of hypotension. However many dialysis patients are found to be hypertensive. In...
Article
Background: Pulmonary agenesis is the complete absence of bronchus, parenchyma and vessels. Unilateral lung agenesis is more common (Aggarwal et al., 2002). Accumulation of bronchial secretions and products of inflammation are chief determinants that determine the degree of respiratory distress (Krivchenya et al., 2000). Anomalies frequently associ...
Article
Background: Retinopathy of prematurity (ROP) is a disease related to low birth weight, prematurity, oxygen administration, and various other factors, which are yet to be identified. Aims: The aim was to find incidence of ROP and risk factors for causation in babies weighing

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