Sophie Sanchez

Sophie Sanchez
Uppsala University | UU · Department of Organismal Biology

PhD

About

126
Publications
30,386
Reads
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1,539
Citations
Citations since 2017
76 Research Items
1077 Citations
2017201820192020202120222023050100150200250
2017201820192020202120222023050100150200250
2017201820192020202120222023050100150200250
2017201820192020202120222023050100150200250
Additional affiliations
April 2014 - April 2018
Uppsala University
Position
  • Lecturer
March 2010 - March 2012
European Synchrotron Radiation Facility
Position
  • PostDoc Position

Publications

Publications (126)
Article
Full-text available
Detailed histological analyses are desirable for zebrafish mutants that are models for human skeletal diseases, but traditional histological techniques are limited to two-dimensional thin sections with orientations highly dependent on careful sample preparation. On the other hand, techniques that provide three-dimensional (3D) datasets including µC...
Article
The origin and early diversification of jawed vertebrates involved major changes to skeletal and soft anatomy. Skeletal transformations can be examined directly by studying fossil stem gnathostomes; however, preservation of soft anatomy is rare. We describe the only known example of a three-dimensionally mineralized heart, thick-walled stomach, and...
Article
Full-text available
The Cretaceous–Palaeogene mass extinction around 66 million years ago was triggered by the Chicxulub asteroid impact on the present-day Yucatán Peninsula1,2. This event caused the highly selective extinction that eliminated about 76% of species3,4, including all non-avian dinosaurs, pterosaurs, ammonites, rudists and most marine reptiles. The timin...
Article
Full-text available
Significance Some lineages of organisms have undergone major evolutionary radiations, while others have not. Establishing why is a central goal of evolutionary research. Whole-genome duplication (WGD) is often proposed as having caused the spectacular evolutionary radiation of teleost fishes. However, due to the absence of genetic data for fossil s...
Article
Full-text available
Teleost fishes comprise one-half of all vertebrate species and possess a duplicated genome. This whole-genome duplication (WGD) occurred on the teleost stem lineage in an ancient common ancestor of all living teleosts and is hypothesized as a trigger of their exceptional evolutionary radiation. Genomic and phylogenetic data indicate that WGD occurr...
Preprint
Full-text available
The Cretaceous-Paleogene (KPg) mass extinction ~66 million years ago (Ma) was triggered by the Chicxulub impact on the present-day Yucatán Peninsula. This event caused the extinction of circa 76% of species, including all non-avian dinosaurs, and represents one of the most selective extinctions to date. The timing of the impact and its aftermath ha...
Article
Full-text available
Thyestiids are a group of osteostracans (sister‐group to jawed vertebrates) ranging in time from the early Silurian to Middle Devonian. Tremataspis is unique among thyestiids in having a continuous mesodentine and enameloid cover on its dermal elements, and an embedded pore‐canal system divided into lower and upper parts by a perforated septum. The...
Article
Full-text available
The production of blood cells (haematopoiesis) occurs in the limb bones of most tetrapods but is absent in the fin bones of ray-finned fish. When did long bones start producing blood cells? Recent hypotheses suggested that haematopoiesis migrated into long bones prior to the water-to-land transition and protected newly-produced blood cells from har...
Article
Full-text available
The ontogenetic trajectory of a marginal jawbone of Lophosteus superbus (Late Silurian, 422 Million years old), the phylogenetically most basal stem osteichthyan, visualized by synchrotron microtomography, reveals a developmental relationship between teeth and dermal odontodes that is not evident from the adult morphology. The earliest odontodes ar...
Article
Full-text available
Growth plate and articular cartilage constitute a single anatomical entity early in development but later separate into two distinct structures by the secondary ossification center (SOC). The reason for such separation remains unknown. We found that evolutionarily SOC appears in animals conquering the land - amniotes. Analysis of the ossification p...
Article
Full-text available
Growth plate and articular cartilage constitute a single anatomical entity early in development but later separate into two distinct structures by the secondary ossification center (SOC). The reason for such separation remains unknown. We found that evolutionarily SOC appears in animals conquering the land - amniotes. Analysis of the ossification p...
Article
Full-text available
Growth plate and articular cartilage constitute a single anatomical entity early in development, but later separate into two distinct structures by the secondary ossification center (SOC). The reason for such separation remains unknown. We found that evolutionarily SOC appears in animals conquering the land - amniotes. Analysis of ossification patt...
Preprint
Full-text available
Ontogenetic data obtained by synchrotron microtomography of a marginal jawbone of Lophosteus superbus (Late Silurian, 422 Million years old), the phylogenetically basalmost stem osteichthyan, reveal developmental relationships between teeth and ornament that are not obvious from the adult morphology. The earliest odontodes are two longitudinal foun...
Article
Full-text available
Tetrapod life on land was the result of a lengthy process, the final steps of which resulted in full independence of amniotic tetrapods from the aquatic environment. Developmental strategies, including growth rate and the attainment of sexual maturity, played a major role in this transition. Early amniotes, such as Ophiacodon, tended to reach sexua...
Article
Osteocytes, cells embedded within the bone mineral matrix, inform on key aspects of vertebrate biology. In particular, a relationship between volumes of the osteocytes and bone growth and/or genome size has been proposed for several tetrapod lineages. However, the variation in osteocyte volume across different scales is poorly characterised, and mo...
Article
Full-text available
Studies on living turtles have demonstrated that shells are involved in the resistance to hypoxia during apnea via bone acidosis buffering; a process which is complemented with cutaneous respiration, transpharyngeal and cloacal gas exchanges in the soft-shell turtles. Bone acidosis buffering during apnea has also been identified in crocodylian oste...
Preprint
Full-text available
Osteocytes, cells embedded within the bone mineral matrix, inform on key aspects of vertebrate biology. In particular, a relationship between volumes of the osteocytes and bone growth and/or genome size has been proposed for several tetrapod lineages. However, the variation in osteocyte volume across different scales is poorly characterised, and mo...
Preprint
Full-text available
The growth of long bones occurs in narrow discs of cartilage, called growth plates that provide a continuous supply of chondrocytes subsequently replaced by newly formed bone tissue. These growth plates are sandwiched between the bone shaft and a more distal bone structure called the secondary ossification center (SOC). We have recently shown that...
Article
Full-text available
Hyneria lindae is one of the largest Devonian sarcopterygians. It was found in the Catskill Formation (late Famennian) of Pennsylvania, USA. The current study focuses on the palaeohistology of the humerus of this tristichopterid and supports a low ossification rate and a late ossification onset in the appendicular skeleton. In addition to anatomica...
Article
Full-text available
Whether hydroxyapatite (HA) orientation in fossilised bone samples can be non-destructively retrieved and used to determine the arrangement of the bone matrix and the location of muscle attachments (entheses), is a question of high relevance to palaeontology, as it facilitates a detailed understanding of the (micro-)anatomy of extinct species with...
Article
Full-text available
Archaeopteryx is an iconic fossil taxon with feathered wings from the Late Jurassic of Germany that occupies a crucial position for understanding the early evolution of avian flight. After over 150 years of study, its mosaic anatomy unifying characters of both non-flying dinosaurs and flying birds has remained challenging to interpret in a locomoto...
Article
Full-text available
Fossils of juvenile Mesozoic birds provide insight into the early evolution of avian development, however such fossils are rare. The analysis of the ossification sequence in these early-branching birds has the potential to address important questions about their comparative developmental biology and to help understand their morphological evolution...
Article
Full-text available
There are two types of dermal skeletons in jawed vertebrates: placoderms and osteichthyans carry large bony plates (macromery), whereas chondrichthyans and acanthodians are covered by small scales (micromery). Fin spines are one of the last large dermal structures found on micromeric taxa and offer a potential source of histology and morphology tha...
Data
Thin section (S2368) of a dermal plate of Romundina, deposited at the Natural History Museum of Stockholm. Arrows mark the cell lacunae and arrowheads mark the dentine tubules. Note the different colors of the outer layer and the inner layer, both of which have dentine tubules and cell lacunae. (TIF)
Article
Full-text available
Palaeospondylus gunni Traquair, 1890 is an enigmatic Devonian vertebrate whose taxonomic affinities have been debated since it was first described. Most recently, Palaeospondylus has been identified as a stem-group hagfish (Myxinoidea). However, one character questioning this assignment is the presence of three semicircular canals in the otic region of...
Conference Paper
Full-text available
In order to understand the ecological dimension of the fish-tetrapod transition, which occurred within the tetrapod stem group during the Devonian Period (419-359 million years ago), we need life-history data from transitional forms. Only recently have serious attempts begun to utilize limb-bone histology as a source of such data. Here we present h...
Conference Paper
Full-text available
Recently, attempts have been made to utilize limb-bone histology as a source of data for understanding the ecological dimension of the fish-tetrapod transition. Here we present histological life history data from a humerus (ANSP 21483) of Hyneria lindae, a fish member of the tetrapod stem group from the Late Devonian Catskill Formation (Pennsylvani...
Article
Full-text available
The numerous cushion-shaped tooth-bearing plates attributed to the stem group osteichthyan Lophosteus superbus, which are argued here to represent an early form of the osteichthyan inner dental arcade, display a previously unknown and presumably primitive mode of tooth shedding by basal hard tissue resorption. They carry regularly spaced, recumbent...
Article
Full-text available
Placoderms are considered as the first jawed vertebrates and constitute a paraphyletic group in the stem-gnathostome grade. The acanthothoracid placoderms are among the phylogenetically most basal and morphologically primitive gnathostomes, but their neurocranial anatomy is poorly understood. Here we present a near-complete three-dimensional skull...
Data
Anatomical abbreviations used in the figures. (XLS)
Data
Romundina stellina, MNHN.F.CPW1, filling of the internal structures and rotation around the specimen. (0400–0750 (Nouveau).avi: Maya Autodesk; 25 MB. (AVI)
Data
Romundina stellina, MNHN.F.CPW1, rotation of the endocranial cavity. olaf_002: Mimics; 5,28 MB. (AVI)
Data
Romundina stellina, MNHN.F.CPW1, rotation of the right inner ear. olaf_006: Mimics; 8,61 MB. (AVI)
Data
Remark concerning the myodomes and the extrinsic muscles in the orbit. (DOC)
Data
Romundina stellina, MNHN.F.CPW1, complete run-through (contrasted) (complete_runthrough_contrasted_avi.avi; 19,8 MB). ImageJ. (AVI)
Data
Skull of Romundina stellina Ørvig, 1975. Specimen MNHN.F.CPW6. A. Dorsal view. B. Left lateral view. C. anterior view. D. posterior view. Scale bar 10 mm. Notice in B the light in the foramen for the pituitary vein indicating that it opens in a canal opening in the right orbit. (TIF)
Data
Romundina stellina, MNHN.F.CPW1, rotation of the dermal bone and perichondral bone vasculature (vertical_rotation.avi; VG StudioMax, SS and PT). (AVI)
Data
Romundina stellina, MNHN.F.CPW1, apparition of the 3D model emerging from below the photograph of the actual specimen. The dermal skull roof opens to reveal the internal perichondral structures. 0001–0125 (nouveau).avi: Maya Autodesk; 3,88 MB. (AVI)
Data
Romundina stellina, MNHN.F.CPW1, rotation around the internal perichondral bone ossification, revealing the lace pattern. 0125–400 (nouveau).avi: Maya Autodesk; 21,3 MB. (AVI)
Data
Romundina stellina, MNHN.F.CPW1,: rotation of model with external perichondral bone opaque. olaf_004; Mimics;16,9 MB. (AVI)
Data
Romundina stellina, MNHN.F.CPW1, rotation of model with external perichondral bone semitransparent. olaf_005; Mimics;16,9 MB. (AVI)
Data
Romundina stellina, MNHN.F.CPW1, rotation of left inner ear. olaf_007; Mimics; 8,35 MB. (AVI)
Data
Romundina stellina, MNHN.F.CPW1, rotation of opaque dermal bone of the skull roof. olaf_012; Mimics; 14 MB. (AVI)
Data
Romundina stellina, MNHN.F.CPW1, endocranial cavity filled plus cranial nerves plus part of the sensory line system. olaf_020: Mimics; 7,73 MB. (AVI)
Data
Romundina stellina, MNHN.F.CPW1, rotation of external perichondral bone semitransparent with internal vacularization opaque. olaf_021; Mimics; 12,1 MB. (AVI)
Data
Romundina stellina, MNHN.F.CPW1, rotation of endocranial cavity, inner ears and right endolymphatic duct. olaf_019; Mimics; 10,5 MB. (AVI)
Data
Romundina stellina, MNHN.F.CPW1, rotation of model without external perichondral and dermal bone. olaf_003; Mimics;11,4 MB. (AVI)
Data
Romundina stellina, MNHN.F.CPW1, rotation of dermal bone vasculature, nerves, arteries and veins. olaf_010; Mimics; 12,5 MB. (AVI)