Sofia Morazzo

Sofia Morazzo
St. Ann's University Hospital Brno | FNUSA-ICRC · International Clinical Research Center (ICRC)

Doctor of Veterinary Medicine
PhD student in the Biomedical Sciences - Molecular Biology, Cancer Biology

About

2
Publications
197
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4
Citations
Introduction
Currently focused in exploring the MAPK signaling pathway in breast cancer, particularly, MAPK6 (ERK3) in breast cancer cell invasiveness.

Publications

Publications (2)
Chapter
Mare endometrial function involves innumerous mediators as hormones (progesterone, estradiol, oxytocin, prostaglandins), cytokines, nitric oxide, enzymes and others. When this complex interaction is disrupted reproductive function is impaired. While some mares carry on a pregnancy to term, others develop recurrent post-breeding endometritis and chr...
Article
Full-text available
Although proteases found in neutrophil extracellular traps (NETs) have antimicrobial properties, they also stimulate collagen type 1 (COL1) production by the mare endometrium, contributing for the development of endometrosis. Cathepsin G (CAT), a protease present in NETs, is inhibited by specific inhibitors, such as cathepsin G inhibitor I (INH; β-...

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Projects

Project (1)
Project
- To discover new signalling components of ERK3 pathway - To determine if ERK3 has a role in proliferative and/or migratory behavior of normal and cancer cells - To determine if ERK3 is an important component of invasive phenotype of cancer cells