Sivaperuman Saravanan

• M.Sc., Ph.D. (Chemistry)
• Professor (Assistant) at Ayya Nadar Janaki Ammal College

Title compounds (V) are prepared in two steps by condensation of N-alkylamines with aromatic aldehydes followed by microwave-assisted addition of thioglycolic acid to imines (III), both under solventless conditions.

This article describes the acetic anhydride induced rearrangement of nitrone to amide and the addition of Grignard reagent to the nitrones yielding substituted hydroxylamines. It has been found that the conversion of C-phenyl-N-(1-methyl- 2-aryl)ethyl nitrones 1 to N-(1-methyl-2-arylethyl) arylcarboxamides 2 is clean, selective and quantitative und...

Only one of the two keto groups of the title compound (I) reacts with hydrazine.

The reactions of 2-(4,5-dihydrothiazol-2-ylthio)-1-arylethanone with different nucleophiles including semicarbazide hydrochloride, hydroxylamine hydrochloride, hydrazine, ethylenediamine and aminoethanol have been investigated, and the formation of a variety of products with different reagents is highlighted.

The 1H and 13C NMR spectral features of l, l-bis(carbethoxy)-2-aryl-4- phenyl/(4-chlorophenyl)-4-oxobutane la-j and their carbonyl derivatives 2a-e are discussed in the light of their diastereotopic characteristics and preferred conformational structures for 1 and 2 are proposed.

The H-1 and C-13 NMR spectral features of 1,1-bis(carbethoxy)-2-aryl-4-phenyl/(4-chlorophenyl)-4-oxobutane 1a-j and their carbonyl derivatives 2a-e are discussed in the light of their diastereotopic characteristics and preferred conformational structures for 1 and 2 are proposed.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

The chemoselective reactions of selenium dioxide with differently substituted adducts generated by 1,4-addition on benzylidene acetophenone are described. This reaction has been shown to be dependent on the nature of the substituent present, leading to different products by α-oxidation/α-oxidation followed by dehydrogenation/dehydrogenation, enoliz...

The synthesis and characterization of new 5-(2-nitro-l-arylpropyl)-4-aryl- 1,2,3-selenadiazoles, obtained from the α-functionalised semicarbazones are described. The structures of these compounds have been established by 1H and13C NMR spectral data.

The synthesis and characterization of new 5-(2-nitro-l-arylpropyl)-4-aryl-1,2,3-scienadliazoles, obtained from the alpha-functionalised semicarbazones are described. The structures of these compounds have been establislieci by (1)H and (13)C NMR spectral data.

The synthesis of a new set of selenadiazoles, 4-aryl-5-(1-aryl-2-methyl-2-nitropropyl)-1,2,3-selenadiazoles (4) derived from 2-[4-methyl-4-nitro-1,3-diarylpentylidene]-1-hydrazinecarboxamide (3) has been reported. THF has been found to be the solvent of choice for this reaction. Structural features of 3 and 4 have been analyzed by NMR and X-ray tec...

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

A novel method for the synthesis of 1,3-enynes is described through oxidative cyclization of the semicarbazones of Michael adducts having potential nitrile functionality. Reaction of these 1,3-enynes with diaryl nitrones has yielded a diastereomeric mixture of highly substituted 2,3-dihydro-1H-pyrrole derivatives via a tandem regioselective additio...

In the title compound, C22H21N3O6Se, the heterocyclic ring makes dihedral angles of 50.03 (11) and 67.75 (11)°, respectively, with the benzene and phenyl rings. The terminal C atoms of the ester groups are disordered over two positions: the site occupancies for the C atoms are 0.62 (3)/0.38 (3) and 0.48 (3)/0.52 (3). In the crystal structure, weak...

The reaction of hydroxylamine hydrochloride with ethyl 3-aroyl-1-cyano-4-hydroxy-2,4,6-triarylcyclohexanecarboxylate has led to the formation of ethyl 2-[amino(hydroxyimino)methyl]-3-aryl-5-(hydroxyimino)-5-arylpentanoate via a tandem ring opening and oximation process. The structures of the products are confirmed by NMR and X-ray techniques, and t...

In the title compound, C18H15Cl2N3O2Se, the selenadiazole ring makes dihedral angles of 49.87 (3) and 55.70 (3)° with the two benzene rings. The dihedral angle between the two benzene rings is 11.90 (5)°. In the crystal structure, intramolecular C—H...O and C—H...Se interactions and intermolecular C—H...O, C—H...Cl and C—H...N interactions are obse...

In the title compound, C18H15Cl2N3O2Se, the selenadiazole ring makes dihedral angles of 49.87 (3) and 55.70 (3)° with the two benzene rings. The dihedral angle between the two benzene rings is 11.90 (5)°. In the crystal structure, intra­molecular C—H⋯O and C—H⋯Se inter­actions and inter­molecular C—H⋯O, C—H⋯Cl and C—H⋯N inter­actions are observed.

In the title compound, C22H21N3O6Se, the heterocyclic ring makes dihedral angles of 50.03 (11) and 67.75 (11)°, respectively, with the benzene and phenyl rings. The terminal C atoms of the ester groups are disordered over two positions: the site occupancies for the C atoms are 0.62 (3)/0.38 (3) and 0.48 (3)/0.52 (3). In the crystal structure, weak...

In the title compound, C18H17N3O2Se, the selenadiazole ring makes dihedral angles of 37.71 (8) and 66.79 (6)° with the adjacent phenyl ring and the aromatic ring of the phenylpropyl group, respectively. The molecular structure is stabilized by weak intramolecular C—H...Se interactions and the crystal packing is stabilized by a weak C—H...π interact...

In the title compound, C18H17N3O2Se, the selenadiazole ring makes dihedral angles of 37.71 (8) and 66.79 (6)° with the adjacent phenyl ring and the aromatic ring of the phenyl­propyl group, respectively. The mol­ecular structure is stabilized by weak intra­molecular C—H⋯Se inter­actions and the crystal packing is stabilized by a weak C—H⋯π inter­ac...

In the title compound, C19H19N3O2Se, the heterocyclic ring makes dihedral angles of 40.74 (12) and 70.38 (15)° with the phenyl and methylphenyl rings, respectively. The molecular structure is stabilized by weak intramolecular C—H...Se interactions, and the crystal packing is stabilized by weak C—H...π interactions.

The reaction of hydroxylamine hydrochloride with ethyl 3‐aroyl‐1‐cyano‐4‐hydroxy‐2,4,6‐triarylcyclohexanecarboxylate has led to the formation of ethyl 2‐[amino(hydroxyimino)methyl]‐3‐aryl‐5‐(hydroxyimino)‐5‐arylpentanoate via a tandem ring opening and oximation process. The structures of the products are confirmed by NMR and X‐ray techniques, and t...

In the title compound, C19H18ClN3O2Se, the heterocyclic ring makes dihedral angles of 40.74 (12) and 51.76 (11)° with the chlorophenyl and methylphenyl rings, respectively. The molecular structure is stabilized by weak intramolecular C—H...Se and C—H...O interactions, and the crystal packing is stabilized by weak intermolecular C—H...O interactions...

In the title compound, C19H19N3O2Se, the heterocyclic ring makes dihedral angles of 40.74 (12) and 70.38 (15)° with the phenyl and methyl­phenyl rings, respectively. The mol­ecular structure is stabilized by weak intra­molecular C—H⋯Se inter­actions, and the crystal packing is stabilized by weak C—H⋯π inter­actions.

In the title compound, C19H18ClN3O2Se, the heterocyclic ring makes dihedral angles of 40.74 (12) and 51.76 (11)° with the chloro­phenyl and methyl­phenyl rings, respectively. The mol­ecular structure is stabilized by weak intra­molecular C—H⋯Se and C—H⋯O inter­actions, and the crystal packing is stabilized by weak inter­molecular C—H⋯O inter­action...

Synthesis of novel 1,2,3-selena/thiadiazoles, linked to different benzo-1,3-heteroazole ring by sulfur has been reported. Structural features of the compounds have been analyzed by 1H and 13C NMR, mass and single crystal X-ray studies.

The synthesis and characterization of a new set of selenadiazoles, 3-aryl-3-[4-aryl-1,2,3-selenadiazol-5-yl]-2-phenyl-2-propenenitrile derived from corresponding semicarbazones have been reported. The structural features of selenadiazoles synthesized have been analyzed by 1H NMR, 13C NMR and X-ray techniques.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

The title compound, C17H17N5OS, adopts the configurations Z around the imine C=N bond and E around the C(O)—NH bond. The configurations are stabilized by two intra­molecular N—H⋯N hydrogen bonds. In the crystal structure, mol­ecules are linked together by N—H⋯O hydrogen bonds, forming a three-dimensional network.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

The chemoselective reaction of hydrazine on the ketone rather than the ester in a gem diester system with a γ‐keto group by hydrazinium sulfate and a tandem deesterification of one of the esters in this system by N,N‐dimethylformamide are reported.

The mass spectra of diethyl 2-[aryl(4-aryl-1,2,3-selenadiazol-5-yl)methyl] malonaic have been studied by electron impact method using high resolution mass spectrometry. The X-ray structure of a representative compound is also investigated.

magnified image magnified image The synthesis of a new set of selenadiazoles, 4‐aryl‐5‐(1‐aryl‐2‐methyl‐2‐nitropropyl)‐1,2,3‐selenadiazoles ( 4 ) derived from 2‐[4‐methyl‐4‐nitro‐1,3‐diarylpentylidene]‐1‐hydrazinecarboxamide ( 3 ) has been reported. THF has been found to be the solvent of choice for this reaction. Structural features of 3 and 4 hav...

The 1,3-tautomerism associated with 2-(2-hydroxy-5-substituted-aryl)benzimidazoles was studied in different solvents. The effect of hydrogen bonding involving the hydroxyl group of the 2-aryl ring on the tautomerism was investigated using NMR spectroscopy. The influence of the solvent concentration on 2-(2-hydroxy-5-chloroaryl)benzimidazole was stu...

The conformational features of diethyl 2-[3-{2-(aminocarbonyl)hydrazono}-1-(4-methoxyphenyl)-3-phenylpropyl]malonate are analysed in solid and solution states in the light of the diastereotopic characteristics, and compared with that of {3-[4-(N,N-dimethylamino)phenyl]-1-(4-methylphenyl)-3-(phenylsulfanyl)propylidene} semicarbazide.

For Abstract see ChemInform Abstract in Full Text.

Synthesis and characterization of several diethyl 2-[aryl(4-aryl-1,2,3-selenadiazol-5-yl)methyl]malonates are reported.

In the title compound, C25H28N4OS, the benzene rings are nearly perpendicular to the central C—C—C—S linkage, whereas the semicarbazide plane forms a dihedral angle of 67.7 (1)° with the central linkage. In the crystal structure, inversion-related mol­ecules exist as N—H⋯O hydrogen-bonded dimers.

In the title compound, C25H28N4OS, the benzene rings are nearly perpendicular to the central C—C—C—S linkage, whereas the semicarbazide plane forms a dihedral angle of 67.7 (1)° with the central linkage. In the crystal structure, inversion-related mol­ecules exist as N—H…O hydrogen-bonded dimers.