Sirshendu Chatterjee

• M.Sc, M.Tech, Ph.D.
• Professor (Associate) at Techno India University West Bengal)

The healing activity of gallic acid enriched ethanolic extract (GAE) of Phyllanthus emblica fruits (amla) against the indomethacin-induced gastric ulceration in mice was investigated. The activity was correlated with the ability of GAE to alter the cyclooxygenase- (COX-) dependent healing pathways. Histology of the stomach tissues revealed maximum...

The current study aims to determine the healing activity of water soluble polysaccharide-rich fraction of a wild mushroom, Termitomyces eurhizus (TEps) against the indomethacin induced gastric ulceration in mice model. Gastric tissue histology, myeloperoxidase (MPO) activity, cyclooxygenases (COX) 1 and 2 expression, prostaglandin E2 (PGE2) synthes...

L-Theanine is a unique non-protein-forming amino acid present in tea [Camellia sinensis (L.) O. Kuntze]. In the present work, we evaluated the healing effect of L-theanine on NSAID (indomethacin)-induced gastric ulcer. Histology of the stomach tissues revealed maximum ulceration on the third day after indomethacin administration (18 mg/kg, single d...

Tea is known as nature low calorie wonder drink. Consumption of hot tea decoction became popular from the ancient times. Currently researchers observed that many secondary metabolites that are heat sensitive might get destroyed on heating. Moreover people, who are permanently live at higher altitude or the members of high altitude expedition team,...

Escherichia coli is a gram- negative bacteria and is common for bacterial disease that affects the intestinal tract. DNA gyrase A was an enzyme which is responsible for DNA breakage and reunion are mostly released by Escherichia coli bacteria in human gastrointestinal tract, causing a situation called gastroenteritis. Normally in native DNA gyrase...

Background: Mangifera indica L. Known as the mango, is a type of flowering plant in the Anacardiaceae family that has been grown for thousands of years in India. Mango fruit is a source of fiber, essential amino acids and number of vitamins and other phytochemicals. Traditional medicine systems have widely used different parts of mango plant as a p...

Plants are proved as a beneficial source of natural products having therapeutic uses for long back periods. Epidemiological studies suggested that approximately 33% of drugs in developed countries are derived from a plant. Pithecellobium dulce is one of the plants which have significant diverse medicinal properties. It is a native fruit of tropical...

Indian spices and medicinal herbs are well known throughout the world. Both have many different physiological and pharmacological characteristics. The current biomedical research is mostly concentrated on finding chemicals extracted from natural sources that are pharmacologically efficient and have little to no side effects for application in food...

Cancer is considered a fatal disease across the globe, irrespective of the economic or social condition of any country. Therefore, the search for its effective cure is one of the most crucial tasks for humankind. Even after extensive research, many patients around the world still face the adversities of this incurable malady. According to ancient a...

Over the last few decades, seed-mediated nutraceutical-based research for dietary phytonutrients has expanded on a large scale. But most often, the seeds of the edibles are excluded as worthless material, beyond having enough understanding about their efficiency as an origin of biologically effective resources. Momordica charantia Linn. commonly no...

Cancer, being a multiphase approach and portrayed by sporadic differentiation of cells, often penetrates and damages the healthy neighbouring cells inside the body, therefore causing an additional degree of inequality. There are multiple causative agents, for example, tobacco smoking, exposures to various hazardous chemicals, or some dietary factor...

The aetiology of breast cancer is complicated. In population health, breast cancer significantly impacts the most typical invasive malignancy and the second most typical death source for women. The most crucial point for the best prognosis is identifying early-stage cancer cells. The conventional diagnostics test for breast cancer includes a physic...

Objectives: The anticancer effect of an Indian herbal preparation was studied under a cancer cell line, as well as the in silico computational methods that explain the probability of protein ligands binding to ER- α and HER-2 receptors. Method: The in vitro anticancer activity of Body Revival® suspension (BR) was determined using cytotoxicity tests...

Moringa oleifera (Family-Moringaceae) is a native plant of India but also seen in tropical and subtropical region of the world. It is commonly known as "drumstick tree" but in Bengali it is known as "Sajne." Every part of the plant is rich in nutritive components. The leaves, bark, roots, pods and flowers are rich in essential vitamins, minerals an...

Moringa oleifera (Family-Moringaceae) is a native plant of India but also seen in tropical and subtropical region of the world. It is commonly known as "drumstick tree" but in Bengali it is known as "Sajne." Every part of the plant is rich in nutritive components. The leaves, bark, roots, pods and flowers are rich in essential vitamins, minerals an...

Oestrogen synthesis pathway is one of the bottom line steps for breast cancer advancement; involving, aromatase enzyme (Cyp450), which transform androgens to oestrogens. Thus endocrine-based therapies comprising of human aromatase blockage is the most necessary way in order to decrease the oestrogen levels and thereafter prohibiting the chances of...

Computer aided drug designing as well as drug repurposing implies the usage of molecular modelling techniques like analysis of the structures of receptor and ligand, molecular docking, pharmacokinetics and toxicity prediction, to explain the bioactivity of the synthetic molecules or plant secondary metabolites to design more efficient drug candidat...

Background: Nanotechnology, concerned with the nanoparticles having a size of 1-100 nm in one dimension is one of the ultimate expeditiously advanced areas of technology that has opened up many new edges of research for modern day society. These nano-conjugates can be synthesized via different methods. Although, the green approach is the most favou...

Vitamin C is a vital circulating antioxidant with anti-inflammatory and immune-boosting properties that are required for good health throughout the life cycle. The coronavirus disease (SARSCov-2) pandemic is now being done; every doctor has suggested consuming vitamin C as a dietary supplement. Besides an extensive range of significances, we want t...

There are many Cassia species which are used in preparing diverse range of herbal products. As per the necessity the present review study reports that Cassia fistula used as medicinal plant for curig various critical diseases. Cassia fistula belong Caesalpinaceae family, commonly known Bandarlati or Sondal. The plant generally grows in India, Bangl...

Plant pigments are one of the main groups of vegetal active principles, with the most crucial therapeutic role. Plant pigments have vital role in the maintenance of human health as well as in the environmental parameters. The major plant pigments are chlorophylls, carotenoids, flavonoids, anthocyanins and betalains. During photosynthesis, green...

The use of nutraceuticals, i.e., food components or their extracts, as well as nutrition supplements, can be used as a means of protecting against oxidative stress and other diseases associated with it. In addition to their high antioxidant capacities, nutraceuticals are recognized as a useful method of preventing oxidative stress. Oxidative stre...

Nanotechnology belongs to one of the areas of modern science, demonstrated numerous positive developments in the realm of medical research, basically deals with the particle size ranging between 1-100 nm. Out of so many methods for developing the metal nanoparticles, the green approach for metal nanoparticles preparation is less hazardous, eco-frie...

The outbreak of the COVID-19 pandemic has caused a severe public health disaster across the planet. The infection may result in a cough, cold, fever, exhaustion, pneumonia, pulmonary troubling syndrome or may be mortality. From starting of the COVID-19 pandemic time folkloric herbal treatments with significant effects have been applied alone or in...

The pollution of the environment by heavy metals is becoming a serious problem. Environmental pollution directly or indirectly influences the condition of atmosphere, biosphere, hydrosphere, pedosphere and lithosphere. Heavy metals that are present in environment are outcome from industrial, thermal, and nuclear pollution. Non-biodegradable, heavy...

Recently, there has been an increasing study on seeds so as to use them as potential sources of therapeutics because they contain many bioactive secondary metabolites. Our experimental research focused mostly on comparing quantified phyto-nutrient estimations, assessing the antioxidant and antibacterial properties of raw and ripe Carica papaya seed...

Citrus Bioactive Compounds Mediated In-Silico Therapeutic Arbitration against Human Aromatase Cytochrome P450: A Traditional Path of Phytotherapy

People throughout the world have long used various fruits, leaves, and plant parts as nutraceuticals and valuable sources of herbal treatments. Apples (Malus domestica) are a popular fruit with a high level of medicinal efficacy, whose seeds have also demonstrated a very high therapeutic and nutritional value when ingested in the right amount and f...

Ayush Kwath (AK), a traditional herbal remedy from India, is used to treat viral and bacterial infections of the respiratory tract. A GC-MS analysis of essential oils isolated from AK revealed 52 components, of which 10 had known medicinal uses. These substances included α-zingiberene, α-curcumene, cinnamaldehyde, β-caryophyllene), β-bisabolene, β-...

Background: Coronavirus (SARS-CoV-2), the leading cause of the epidemic in 2019, also known as COVID-19, has raised ongoing global concerns. The most favourable target protein for this flu is 3CLpro (conserved 3-chymotrypsin-like protease), also known as Mpro. Covaxin and Covishield vaccination is going in India. Remdesivir, as well as some antimal...

Tea harbours more than 700 bioactive compounds viz, different classes of polyphenols, unique amino acid L-Theanine, alkaloids (Caffeine, Theobromine), and Volatile Flavor Compounds (VFC). Tea's polyphenols make its inherent therapeutic potential unlimited. Tea's significance in managing cancer, diabetes, stomach ulcer, influenza, neurological disea...

Consumption of various foods and maintaining a diet inhibit or promote human breast cancer development. Different types of fats have different effects on breast cancer development. Meat consumption is associated with exposure to heterocyclic amine (HCA), alcohol consumption may increase the risk of breast cancer risk, different fibre shows differen...

Chlorophyll, a member of an essential class of green pigments, is predominantly found in all mature plant cells, whether in the leaf of a green plant or any photosynthetic organisms, including cyanobacteria or algal species. The primary function of this pigment is to convert the light energy into chemical energy through a series of synthesizing sev...

Herbs are an important source of bioactive substances. These are widely used to treat several disorders for better function in the human body, minimum toxic effects, and widespread availability. A total of two medicinal herbs from West Bengal, India, such as Oldenlandia corymbosa (Diamond flower) and Ocimum sanctum (Holy basil), are being considere...

Herbs are an important source of bioactive substances. These are widely used to treat several disorders for better function in the human body, minimum toxic effects, and widespread availability. A total of two medicinal herbs from West Bengal, India, such as Oldenlandia corymbosa (Diamond flower) and Ocimum sanctum (Holy basil), are being consid...

Trianthema portulacastrum Linn. (Biskhapra) is an annual herb belongs to the family Aizoacae, which is used to treat for many oxidative stresses related diseases. The current study was done to characterize the organoleptic and proximate characteristics and to estimate the phytochemical components and to investigate antioxidant activity of aqueous e...

Breast cancer on becoming one of the leading cancer types, emerged as an important barrier in increasing life expectancy of the overall population. In the current study, some compounds were screened based on literature survey for the identification of natural bioactive compounds as potential inhibitors of Lyn tyrosine kinase. Therefore, a multi-ste...

Tabernaemontana divaricata Linn. is an ornamental, evergreen and highly useful ethno medicinal plant which is utilized for various traditional treatment purposes worldwide. The plant is commonly called Crepe Jasmine and it is belonging to the family of Apocynaceae. The plant is found in Asia, Australia, China, Japan, India and Myanmar. The plant is...

Trianthema portulacastrum Linn. (Biskhapra) is an annual herb belongs to the family Aizoacae, which is used to treat for many oxidative stresses related diseases. The current study was done to characterize the organoleptic and proximate characteristics and to estimate the phytochemical components and to investigate antioxidant activity of aqueou...

The novel anti-neoplastic glycopeptide T11TS retards glioma both in in-vitro clinical samples and in-vivo models. The present study investigates the correlation between altering the glioma microenvironment with glioma arrest and death. Flowcytometry, immunoblotting, ELISA, and co-immunoprecipitation were employed to investigate glioma cell arrest a...

In recent years, focus on plant-oriented research has been increasing as they are potential sources of therapeutic agents comprising secondary metabolites, free antioxidant radicals, and many other well-known phytochemicals that have a high salutary value and massive impact on the healthcare system. Our present research study mainly aims at the com...

Green synthesis of AuNPs that have potential anticancer properties is relatively simple, cheap and eco-friendly compared to the conventional chemical/physical approaches. Quercetin is known for its antioxidant and anticancer properties, i.e., induction of apoptosis, tumour suppression, etc. This study aims to characterize and compare between two di...

The last few decades have witnessed 'one size fits all' kind of conventional treatment strategy i.e. a similar line of treatment or usage of the same drug to treat a particular disease. This approach is not associated with specific personal characteristics but with individual genetic constitutions. Precision oncology holds great opportunities to im...

Cancer-associated genes, Precision Oncology

Vegetables are intrinsic to a healthy diet. But the peels are discarded as food waste, unknowing of their potential as the source of bioactive compounds. The study aims to find the nutritional constituents, antioxidant and antimicrobial activity of these food wastes. Here we make a comparative investigation among the five underutilized vegetable pa...

Air pollution is a significant matter of concern in today’s world. The current study objective is to determine the air pollution tolerance index (APTI) of Kolkata from five roadside medicinal plants, namely, Heliotropium indicum, Tridax procumbens, Cleome rutidosperma, Commelina benghalensis, and Euphorbia hirta. APTI was determined by fresh lea...

References | Article Metrics | Similar Articles Abstract Air pollution is a significant matter of concern in today's world. The current study objective is to determine the air pollution tolerance index (APTI) of Kolkata from five roadside medicinal plants, namely, Heliotropium indicum, Tridax procumbens, Cleome rutidosperma, Commelina benghalensis,...

Vegetables are intrinsic to a healthy diet. But the peels are discarded as food waste, unknowing of their potential as the source of bioactive compounds. The study aims to find the nutritional constituents, antioxidant and antimicrobial activity of these food wastes. Here we make a comparative investigation among the five underutilized vegetable pa...

In nature, there are plenty of medicinal herbs and plants which contain active compounds decisive for their diverse prophylactic/ therapeutic behaviour against many human diseases. A thorough analysis of these phyto-compounds for antimicrobial activities has considered greater importance in the context of recent days. There is an urgent need for al...

Fringed spider flower or purple cleome (Cleome rutidosperma), an important wild weed, has long been known for medicinal and nutritional activities. A close similarities of the seed of it with the mustard seed creates an aura of enthusiasm among us for isolation and analysis of the lipid. Initial qualitative analysis of seed extract showed a charact...

Fringed spider flower or purple cleome (Cleome rutidosperma), an important wild weed, has long been known for medicinal and nutritional activities. A close similarities of the seed of it with the mustard seed creates an aura of enthusiasm among us for isolation and analysis of the lipid. Initial qualitative analysis of seed extract showed a charact...

Non-steroidal anti-inflammatory drugs (NSAIDs) disrupts mucosal defense through inhibition of cyclooxygenase (COX) and depletion of endogenous prostaglandins, thus exerts its adverse effects. Tea flavonoids; catechins and its derivatives, in particular, are known to prevent various systemic diseases like ulcer, cancer, atherosclerosis, hypertension...

Non-steroidal anti-inflammatory drugs (NSAIDs) disrupts mucosal defense through inhibition of cyclooxygenase (COX) and depletion of endogenous prostaglandins, thus exerts its adverse effects. Tea flavonoids; catechins and its derivatives, in particular, are known to prevent various systemic diseases like ulcer, cancer, atherosclerosis, hypertension...

Phyllanthus amarus Linn. (Family: Euphorbiaceae) is found in tropical and subtropical region of the world. It is being used for the treatment of severe microbially infected disorders. The present study quantifies the phytochemical constituents. The present study also evaluated the in vitro antioxidant and antimicrobial properties of aqueous and 70%...

Medicinal plants are the predominant source of phytochemicals and nutraceuticals, and it is used for the treatment of many diseases for its high effectiveness, low cost, and wide availability. In the current research study five, commonly used ethnomedicinal weeds of West Bengal, and India namely; Heliotropium indicum, Tridax procumbens, Cleome ruti...

Phytomedicine and herbal drugs are used in healthcare treatment system from ancient time. Medicinal plants had been used by different societies, ethnic groups and cultures throughout the world since long. Plants are the potential source of medicinal substances which have high pharmacological values and huge utility in healthcare development. Herbal...

Medicinal plants are the only source for the treatment of physiological disorders in ancient days. In India, herbs are always acted as the primary source of traditional medicine. Leucas aspera (Willd.) Link (family-Lamiaceae), an annual herbaceous medicinal weed, and it is locally known as "Shwetdron." The plant is distributed throughout India from...

The ancient world had huge faith on the herbal medicines for curing various ailments. Scoparia dulcis Linn. is a medicinal herb of family Scrophulariaceae is considered to be one of such plants which have remarkable curative property. Scoparia dulcis is the commonly known as Sweet broom weed and is distributed throughout the tropical and subtropica...

Protein is an important primary metabolite of our living systems. There are several studies based upon analysing the different, individual protein sources from various plant species are still on searching mode. On parallel with this context, traditionally edible plants has been proven to be an enriched source of protein based nutrition and large...

Black tea, the most widely consumed aromatic non-alcoholic beverage second to water, is prepared by boiling cured leaves of Camellia sinensis. It is reported that black tea contains plenty of bioactive constituents, including complex polyphenols like theaflavins (TF 2 A, TF 2 B, TF 3) and thearubigins that exhibit a wide range of pharmacological pr...

Trianthema portulacastrum Linn. (Aizoaceae) is an important ethnomedicinal herb which is utilized for various traditional treatment purposes worldwide. It is found in India, Pakistan, Sri Lanka, Africa, West Asia and Tropical America. The plant species are endemic in South America. In Ayurveda, Sidhha and Homeopathy treatment system the plant is us...

Trianthema portulacastrum Linn. (Aizoaceae) is an important ethnomedicinal herb which is utilized for various traditional treatment purposes worldwide. It is found in India, Pakistan, Sri Lanka, Africa, West Asia and Tropical America. The plant species are endemic in South America. In Ayurveda, Sidhha and Homeopathy treatment system the plant is us...

The field of nanotechnology is the most renowned area of research in modern day science. One of the most convenient and comprehensive technique related to the synthesis of nanoparticles using plant extracts and their subsequent action. On the other hand, herbal medicines become an integral part of modern-day treatment strategy around the glob...

The field of nanotechnology is the most renowned area of research in modern day science. One of the most convenient and comprehensive technique related to the synthesis of nanoparticles using plant extracts and their subsequent action. On the other hand, herbal medicines become an integral part of modern-day treatment strategy around the glob...

Oxalis corniculata Linn. is a highly useful and important traditionally used medicinal herbaceous plant which is found in tropical and subtropical areas of the world. The plant is commonly called creeping wood sorrel and it is belonging to the family Oxalidaceae. The plant has been used in different system of traditional medication for the treatmen...

Background: Medicinal plants are a source of phytochemicals and they are used for the treatment of several oxidative stress-related or other diseases for their effectiveness, low toxicity and easy availability. Five traditionally used and less characterized herbaceous weeds of West Bengal, India, namely, Heliotropium indicum, Tridax procumbens, Cle...

Background: Medicinal plants are a source of phytochemicals and they are used for the treatment of several oxidative stress-related or other diseases for their effectiveness, low toxicity and easy availability. Five traditionally used and less characterized herbaceous weeds of West Bengal, India, namely, Heliotropium indicum , Tridax procumbens , C...

Nanotechnology is one of the most rapidly progressing fields of technology, and it has opened up many new frontiers of research for modern society. It deals with the nanoparticles having a size of 1-100 nm in one dimension. These nano-conjugates can be prepared easily by different chemical, physical, and biological approaches. However, the green sy...

Nanotechnology is one of the most rapidly progressing fields of technology, and it has opened up many new frontiers of research for modern society. It deals with the nanoparticles having a size of 1-100 nm in one dimension. These nano-conjugates can be prepared easily by different chemical, physical, and biological approaches. However, the green sy...

Phytochemical Screening and Quantitative Study

Phytochemical Screening Poster

Medicinal plants are the only source for the treatment of physiological disorders in ancient days. In India, herbs are always acted as the primary source of traditional medicine. Leucas aspera (Willd.) Link (family-Lamiaceae), an annual herbaceous medicinal weed, and it is locally known as "Shwetdron." The plant is distributed throughout India from...

Tea, one of the most commonly consumed rejuvenating beverages all across the world, had recently gained immense attention in the field of research with a keen focus on the exploitation of its medicinal value and therapeutic potential as a form of complementary and alternative medicine (CAM). In this backdrop, a very popular natural ingredient clove...

In the recent era, medicinal weeds are receiving massive attention for their therapeutic efficacy on different oxidative stress-related diseases. In the present study, five common medicinal herbaceous weeds of West Bengal, and India namely; Heliotropium indicum, Tridax procumbens, Cleome rutidosperma, Commelina benghalensis, and Euphorbia hirta hav...

Heliotropium indicum Linn. (Family Boraginaceae), an annual herbaceous medicinal plant, is usually known as Indian heliotrope. Glycosmis pentaphylla (Retz.) DC (Family Rutaceae) is a perennial shrub, commonly known as orange-berry. These traditionally used medicinal plants originate from tropical and temperate parts of the world along with India,...

Heliotropium indicum Linn. (Family Boraginaceae), an annual herbaceous medicinal plant, is usually known as Indian heliotrope. Glycosmis pentaphylla (Retz.) DC (Family Rutaceae) is a perennial shrub, commonly known as orange-berry. These traditionally used medicinal plants originate from tropical and temperate parts of the world along with India, S...

Heliotropium indicum Linn. (Family Boraginaceae), an annual herbaceous medicinal plant, is usually known as Indian heliotrope. Glycosmis pentaphylla (Retz.) DC (Family Rutaceae) is a perennial shrub, commonly known as orange-berry. These traditionally used medicinal plants originate from tropical and temperate parts of the world along with India, S...

Heliotropium indicum Linn. (Family Boraginaceae), an annual herbaceous medicinal plant, is usually known as Indian heliotrope. Glycosmis pentaphylla (Retz.) DC (Family Rutaceae) is a perennial shrub, commonly known as orange-berry. These traditionally used medicinal plants originate from tropical and temperate parts of the world along with India, S...

Allamanda cathartica Linn. (Family-Apocynaceae) is a perennial shrub, found in various parts of the world. The common name of the plant is Golden Trumpet flower, and in Bengali, it is known as Harkakra. The plant is also known to deal with heat and different toxic products; it activates blood circulation and diuresis. It works well against snake bi...

In this era of novel technological innovations, human beings have adopted such a changed lifestyle where food intake is devoid of adequate beneficial nutrients. This problem resulted in increased risk of systemic diseases like diabetes, obesity, hypertension, cancer, cardiovascular and various other lifestyle diseases and as remedy, pharmaceutical...

Now a day's herbal medicines are taking the leading positions in the healthcare system. It was the essential driving force for better treatment from ancient time. Commelina benghalensis Linn. belongs to Commelinaceae family is an annual herbaceous weed commonly known as Bengal Dayflower. These plants are found in tropical and temperate parts of the...

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Cleome rutidosperma DC. (Nil Hurhure), belonging to the family Cleomaceae being used for the treatment of oxidative stress related and microbial infected diseases. The research study was carried out to estimate the phytochemical components and to investigate anti-oxidant and anti-microbial activity of aqueous and 70% ethanolic extracts of leaves of...