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  • Sirenia Lizbeth Mondragon Gonzalez
Sirenia Lizbeth Mondragon Gonzalez

Sirenia Lizbeth Mondragon Gonzalez
Sorbonne Université | UPMC · Centre de Recherche de l'Institut du Cerveau et de la Moelle Epinière


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Publications (5)
Full-text available
A prominent electrophysiological feature of compulsive behaviours is striatal hyperactivity; but its underlying dysfunctional cellular mechanisms still need to be characterized. Within the striatum, parvalbumin-positive interneurons (PVI) exert a powerful feedforward inhibition essential for the regulation of striatal activity. To investigate the p...
Full-text available
The analysis of multi-unit extracellular recordings of brain activity has led to the development of numerous tools, ranging from signal processing algorithms to electronic devices and applications. Currently, the evaluation and optimisation of these tools are hampered by the lack of ground-truth databases of neural signals. These databases must be...
Behavioral flexibility is the ability of a subject to change its behavior according to contextual cues. In humans, Obsessive Compulsive Disorders (OCD) is characterized by repetitive behavior, performed through rigid rituals. This phenomenological observation has led to explore the idea that OCD patients may have diminished behavioral flexibility....
Full-text available
Toxoplasma gondii proliferates and organizes within a parasitophorous vacuole in rosettes around a residual body and is surrounded by a membranous nanotubular network whose function remains unclear. Here, we characterized structure and function of the residual body in intracellular tachyzoites of the RH strain. Our data showed the residual body as...


Questions (2)
I would like to know what are the commutator systems that are being used in other labs for in-vivo neural recording (and stimulation) in rodents?
In the lab we tested some cheap non-motorized commutators such as adafruit's and moflon's. The initial mechanical resistance is very high for a mouse to easily make it turn.
I know there are some motorized options but they are super expensive (>4k) and/or super big (need to be installed in the ceiling)
Thank you!
Hi all,
I would like to know your experience/opinion about working with tungsten and nichrome wires to make tetrodes for chronic electrode implants. Which one is the best and why? Assuming they have the same insulation and diameter?
I've heard that some people skip the gold plating stage for tungsten wires, have you done this? 
Thank you


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