Sindre Andre Pedersen

Sindre Andre Pedersen
Norwegian University of Science and Technology | NTNU

PhD

About

83
Publications
6,834
Reads
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1,425
Citations
Citations since 2016
17 Research Items
911 Citations
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Introduction
Trained as an animal physiologist at the Norwegian University of Science and Technology I'm applying my broad research interests in conservation physiology. My research aims to understand how evolutionary pressures have shaped physiological systems and the degree to which adaptation and acclimation to natural and environmental perturbations, such as anthropogenic climate change (e.g. rising temperature and ocean acidification), can occur.

Publications

Publications (83)
Article
Full-text available
Climate change-induced warming and ocean acidification are considered two imminent threats to marine biodiversity and current ecosystem structures. Here, we have for the first time examined an animal's response to a complete life cycle of exposure to co-occurring warming (+3°C) and ocean acidification (+1,600 μatm CO2), using the key subarctic plan...
Article
Full-text available
Background and purpose of article: Crisis Resolution Teams (CRT) for rapid assessment and short-term treatment of mental health problems have increasingly been implemented internationally over the last decades. Among the Nordic countries, the CRT model has been particularly influential in Norway, where 'Ambulante akutteam (AAT)' is a widespread ps...
Article
Full-text available
Sexual and gender minorities, for example, lesbian, gay, bisexual, transgender and questioning (LGBTQ) youth, are overrepresented in the child welfare system and an increasing number of LGBTQ people are becoming foster parents. The objective of this scoping review is to provide an overview of the existing empirical research on the practices of chil...
Article
Full-text available
Breast milk is the primary source of nutrition and hydration for the newborn infant but also plays an important role in the child’s first immune defense. Additionally, several breast milk factors have been implicated in immune-related health outcomes later in life, including immunoglobulins, cytokines, chemokines, growth factors and, more recently,...
Article
Full-text available
Aims To synthesise evidence of the psychometric properties of the Five‐item World Health Organization Well‐being Index in mental health settings and critically appraise the methodologies of the included studies. Design Protocol for a systematic psychometric review. Methods The review protocol has been registered in the International Prospective R...
Article
Full-text available
Background: This paper is a systematic review and meta-analysis of the efficacy of available medications for the treatment of restricted/repetitive behavior (RRBs) in Autism Spectrum Disorder (ASD). Method: We searched MEDLINE, Embase, PsycINFO, The Cochrane Library (Cochrane Database of Systematic Reviews (CDRS), the Cochrane Central Register o...
Article
Full-text available
Background: Blockchain can be described as an immutable ledger, logging data entries in a decentralized manner. This new technology has been suggested to disrupt a wide range of data-driven domains, including the health domain. Objective: The purpose of this study was to systematically review, assess and synthesize peer-reviewed publications uti...
Article
Full-text available
https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-019-1166-6 Background Obsessive-compulsive disorder (OCD) is a chronic mental health disorder characterized by recurring obsessions and compulsions affecting 1–3% of children and adolescents. Current treatment options are limited by accessibility, availability, and quality...
Article
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A growing number of studies are focusing on the associations between human milk (HM) immunological composition and allergic diseases. This scoping review aims to identify statistical methods applied in the field and highlight pitfalls and unmet needs. A comprehensive literature search in MEDLINE and Embase retrieved 13,607 unique records. Following...
Article
Based on few clinical trials, flunarizine is considered a first-line prophylactic treatment for migraine in several guidelines. In this meta-analysis, we examined the pooled evidence for its effectiveness, tolerability, and safety. Prospective randomized controlled trials of flunarizine as a prophylaxis against migraine were identified from a syste...
Article
Full-text available
Background Violence against intimate partners is a worldwide public health problem. Cognitive behavioural therapy delivered in a group format is widely used for the treatment of men’s violent behaviour towards their female partners. A Cochrane review about the effectiveness of this therapy from 2011 revealed a lack of controlled studies. Our aim is...
Article
Based on few clinical trials, flunarizine is considered a first-line prophylactic treatment for migraine in several guidelines. In this meta-analysis, we examined the pooled evidence for its effectiveness, tolerability, and safety. Prospective randomized controlled trials of flunarizine as a prophylaxis against migraine were identified from a syste...
Presentation
Full-text available
Session code: AT20 Session title: e-Mental health interventions Session type: Free Papers Symposium Chair: Glenn Melvin, Australia FP 128: Acceptability, feasibility and effectiveness of iCBT interventions for pediatric OCD: a systematic review L. Babiano Espinosa1, L. Wolters1, V. op de Beek1, S.A. Pedersen2, B. Weidle1, N. Skokauskas1. 1Norges t...
Data
Supplement to the paper "Ocean acidification ameliorates harmful effects of warming in primary consumer"
Article
Context: Migraine is a common problem in children and adolescents, but few satisfactory prophylactic treatments exist. Objective: Our goal was to investigate the pooled evidence for the effectiveness of using biofeedback to reduce childhood migraine. Data sources: A systematic search was conducted across the databases Medline, Embase, CENTRAL,...
Article
The copepod Calanus finmarchicus is a key component of northern Atlantic food webs, linking energy-transfer from phytoplankton to higher trophic levels. We examined the effect of different ocean acidification (OA) scenarios (i.e. ambient, 1080, 2080 and 3080 μatm CO2) over two subsequent generations under limited food availability. Determination of...
Article
Full-text available
Ocean acidification poses an ongoing threat to marine organisms, and early life stages are believed to be particularly sensitive. The boreal calanoid copepod Calanus finmarchicus seasonally dominates the standing stock of zooplankton in the northern North Sea and North Atlantic, and due to its size and abundance is considered an ecological key spec...
Article
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The impact of medium-term exposure to CO 2 -acidified seawater on survival, growth and development was investigated in the North Atlantic copepod Calanus fin-marchicus. Using a custom developed experimental system, fertilized eggs and subsequent development stages were ex-posed to normal seawater (390 ppm CO 2) or one of three different levels of C...
Article
Full-text available
Ocean acidification and possible leakage from subsea CO2 storage may create unfavourable conditions for marine organisms. Deep-living animals are generally believed to be more vulnerable to elevated partial pressure of CO2 (pCO2, environmental hypercapnia) than shallow-living species, but so far only a limited number of studies have investigated th...
Article
With the advent of next generation sequencing, new avenues have opened to study genomics in wild populations of non-model species. Here, we describe a successful approach to a genome-wide medium density Single Nucleotide Polymorphism (SNP) panel in a non-model species, the house sparrow (Passer domesticus), through the development of a 10 K Illumin...
Article
Full-text available
The impact of chronic exposure to CO2-acidified seawater on survival, growth and development was investigated in the North Atlantic copepod Calanus finmarchicus. Using a custom developed microcosm system fertilized eggs and subsequent development stages were exposed to normal seawater (390 ppm CO2) or one of three different levels of CO2-induced ac...
Article
Full-text available
Small populations are likely to have a low genetic ability for disease resistance due to loss of genetic variation through inbreeding and genetic drift. In vertebrates, the highest genetic diversity of the immune system is located at genes within the major histocompatibility complex (MHC). Interestingly, parasite-mediated selection is thought to po...
Article
As the body fluid of freeze-tolerant organisms freezes, solutes become concentrated in the gradually smaller unfrozen fluid fraction, and dissolved trace metals may reach toxic levels. A dialysis technique was used to investigate the metal binding capacity of the low density fraction of the hemolymph from the freeze tolerant beetle Phyto depressus....
Article
Full-text available
Suppression subtractive hybridization (SSH) cDNA library construction and characterization was used to identify differentially regulated transcripts from oil exposure in liver of male Atlantic herring (Clupea harengus) fed a diet containing 900 mg crude oil/kg for 2 mo. In total, 439 expressed sequence tags (EST) were sequenced, 223 from the forwar...
Article
Antifreeze proteins (AFPs) are characterized by their capacity to inhibit the growth of ice and are produced by a variety of polar fish, terrestrial arthropods and other organisms inhabiting cold environments. This capacity reflects their role as stabilizers of supercooled body fluids. The longhorn beetle Rhagium inquisitor is known to express AFPs...
Article
Climatic stressors are environmental factors of paramount importance for biological systems. Numerous examples from terrestrial plants and animals show that, in particular, cold and drought are factors that dictate the distribution of species (for a review see Hoffmann and Parsons, 1991). Indeed, sediment records of insect remains have been convinc...
Chapter
of ice crystals in several cold blooded organisms. First discovered in fish, they have also been found in insects, plants, fungi and bacteria. Antifreeze proteins cause the non-colligative depression of the freezing point of water, a property which has been exploited in the practical applications of antifreeze proteins such as improving the texture...
Article
Antifreeze proteins are a structurally diverse group of proteins characterized by their unique ability to cause a separation of the melting- and growth-temperatures of ice. These proteins have evolved independently in different kinds of cold-adapted ectothermic animals, including insects and fish, where they protect against lethal freezing of the b...
Article
Binding of cadmium (Cd) to metallothionein (MT) and non-MT proteins with low contents of cysteine has been observed in terrestrial arthropods. We recently isolated a Cd-binding protein with no cysteine that was induced in Cd-exposed larvae of the beetle Tenebrio molitor. In this study we have examined the molecular distribution of Cd within extract...
Article
Full-text available
The strategy for cold-hardiness and water balance features of two closely related families of Coleoptera, Cerambycidae and Chrysomelidae, were investigated. Cerambycids were freeze-avoiding with low supercooling points, whereas chrysomelids froze at high temperatures and were tolerant to freezing. Hence, the two families have adopted different stra...
Article
We studied how transcript levels of metallothionein (MT), Cu/Zn-superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX) and glutathione reductase (GR) as well as functional protein levels of MT, SOD and CAT in brown trout tissues changed during a 15-days waterborne exposure to Cd and Zn. Trout from a river with low levels of metals...
Article
The effect of cadmium (Cd) exposure on Cd-binding ligands was investigated for the first time in a beetle (Coleoptera), using the mealworm Tenebrio molitor (L) as a model species. Exposure to Cd resulted in an approximate doubling of the Cd-binding capacity of the protein extracts from whole animals. Analysis showed that the increase was mainly exp...