Sinclair M Gore

Sinclair M Gore
Oxford University Hospitals NHS Trust | OUH NHS · Department of Plastic Surgery

MB BCh MA(Cantab) MD FRCS(Plast)

About

26
Publications
3,956
Reads
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292
Citations
Introduction
Additional affiliations
January 2012 - December 2012
Sydney Head and Neck Cancer Institute
Sydney Head and Neck Cancer Institute
Position
  • Surgical Fellow
January 2007 - August 2008
The Lister Hospital
Position
  • Plastic Surgery Registrar
January 2004 - January 2006
Queen Mary, University of London
Position
  • Research Associate

Publications

Publications (26)
Article
Background: Supraclavicular flap (SCF) repair is widely reported in head and neck surgery in select patients and defects. The authors' objective is to present our series of 30 patients who underwent SCF repair for varying defects and to review the scope and outcome of SCF repair in the literature. Methods: The authors contributed primary evidenc...
Article
Objective: Review factors and outcomes in extensive anterior skull base reconstruction based on scapular tip chimeric free flaps. Methods: Retrospective consecutive case series review of skull base reconstruction using scapular tip chimeric free flaps in one unit, with emphasis on radiological, functional, quality of life, and cosmetic outcome scor...
Article
Full-text available
A best evidence topic was written according to the structured protocol. The three part question addressed was: [In patients undergoing closure of surgical wounds with sutures] does [keeping the wound dry for the first 48 hours after closure] [reduce the incidence of surgical site infections (SSIs)]? 4 relevant papers were culled from the literature...
Article
Background: There are many patient-based and clinician-based scales measuring the severity of facial nerve paralysis and the impact on quality of life, however, the social perception of facial palsy has received little attention. The purpose of this pilot study was to measure the consequences of facial paralysis on selected domains of social perce...
Article
Nodal metastasis from cutaneous squamous cell carcinoma (cSCC) is poorly predicted clinically and is associated with a high mortality rate. From 2010 to 2013, patients with high-risk cSCC were assessed with SNB either at the time of primary cutaneous tumour resection or at secondary wide local excision. Of 57 patients, eight (14%) had nodal metasta...
Chapter
Non-melanoma skin cancer (NMSC) is the most common form of cancer worldwide. In 2008, approximately 430,000 cases of NMSC were diagnosed in Australia; of these, 296,000 were basal cell carcinoma (BCC) and 138,000 were squamous cell carcinoma (SCC) [1, 2]. Whereas many treatment options exist, the mainstay of management is surgical excision with ade...
Article
Background In this study we prospectively audited the impact of head and neck multidisciplinary team meetings (MDM) on patient management.Study design: prospective analysisMethods We collected clinical data, the pre-MDM treatment plan, the post-MDM treatment plans, and follow up data from all patients discussed at a weekly MDM and we recorded chang...
Article
Background The purpose of this study was to compare survival and functional outcomes in patients with advanced oral cavity squamous cell carcinoma (SCC) treated with either surgery + adjuvant radiotherapy (RT) or concurrent chemoradiotherapy (CRT).Methods Patients treated with curative intent by either surgery + RT or concurrent CRT were identified...
Article
Alar reconstruction can be challenging, and numerous solutions for reconstructing this potentially difficult area have been proposed. Our preferred solution is an island inversion flap based upon the superior alar artery. We performed a retrospective review of the medical notes and photographs of 103 consecutive patients undergoing alar reconstruct...
Article
Background: A number of microvascular free-flap tissue transfer techniques exist for reconstruction of head and neck defects. The scapular free flap is a versatile option that can be used for a wide variety of defects in this complex region. Methods: A series of 42 free flaps from 41 patients was retrospectively identified from the senior author...
Article
Full-text available
Objective: The aim of this procedure was to definitively treat periductal mastitis and periareolar sepsis which was previously resistant to multiple surgical procedures and nonoperative treatment of chronic nipple sepsis. Methods: We employed a multidisciplinary approach to the treatment of end-stage periductal mastitis using a combination of ce...
Article
The insertion of sizers in breast augmentation surgery is a common method of predicting the final volume of prosthesis required. However, saline-filled sizers may not accurately represent the shape of the cohesive-gel-augmented breast. PERTHESE cohesive-gel breast implants are produced with matching sets of reusable (sterilizable) cohesive-gel-fill...
Article
Rupture of silicone breast implants is a recognised complication. We report a 36-year-old lady that 16 years post-augmentation presented with a unilateral gradually swollen breast with no associated lymphadenopathy. Ultrasound examination reported implant rupture, and exchange of implants was subsequently performed, only to reveal serous fluid (neg...
Article
Triggering in young children is rare. In this report, we describe spontaneous bilateral ring finger triggering in a 7-year-old boy after a viral infection. The pathology completely resolved without intervention. We propose that the triggering resulted from a viral synovitis. Such a case highlights the importance of eliciting evidence of recent infe...
Article
Although deregulated Hedgehog signalling and elevated Gli transcription factor expression are known to promote the development of basal cell carcinoma (BCC), little is known about molecular mechanisms driving the development of specific growth pattern subtypes. Using gene array analysis, we have previously observed that over-expression of GLI1 in h...
Article
Extremely large chest wall defects may result following salvage oncological surgery. Typically these defects involve a large skin defect combined with a variable resected area of underlying muscle and ribs. In situations where the skin defect is very large the use of a large latissimus dorsi flap may require skin grafting to the donor site if a myo...
Article
This paper describes a useful way of ensuring complete surgical ablation of the germinal matrix of the nail bed by staining the proximal envelope with Bonney's Blue dye.
Thesis
Basal cell carcinoma (BCC) is the most common skin cancer in humans. The demonstration of genetic and protein alterations has, so far, had limited correlation with either biological behaviour or histological classification of these tumours. It was observed that Glil-overexpressing keratinocytes express elevated levels of genes known to be associate...
Article
Polyotia (mirror ear) is an extremely rarely reported congenital anomaly of the external ear. The aetiology of this condition is unclear, and there are few descriptions of surgical techniques used. We aimed to review our experience with this condition by performing a retrospective review of the cases treated in our unit. Eight cases of polyotia tre...
Article
Infection with antibiotic-resistant Acinetobacter spp. is an increasing problem in critical care environments worldwide. Acinetobacter spp. are known to produce an insulin-cleaving protease. We hypothesized that infection with Acinetobacter spp. was associated with the acquisition of glucose intolerance in burn patients. Data were collected prospec...

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