Simone Morganti

Simone Morganti
University of Pavia | UNIPV · Department of Electrical, Computer and Biomedical Engineering

Mechanical Engineering

About

49
Publications
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1,140
Citations

Publications

Publications (49)
Article
Objective Several studies addressed characteristics of aortic wall in patients with bicuspid aortic valve (BAV) compared to those with tricuspid aortic valve (TAV). Different patients population and lack of randomization were the main limitations in many of such studies, focused furthermore, only on ultimate properties (at rupture). In this study w...
Article
Full-text available
Background: Challenging surgical cases are becoming more and more frequent, making the optimization of decision making process and an accurate preoperative planning mandatory in order to improve postoperative outcomes. Aims: Here we present an original multidisciplinary approach aimed at optimizing decision making in a peculiar case of double ao...
Article
Thoracic endovascular aortic repair of the ascending aorta is becoming an option for patients considered unfit for open surgery. Such an endovascular procedure requires careful pre-operative planning and the customization of prosthesis design. The patient-specific tailoring of the procedure may call for dedicated tools to investigate virtual treatm...
Article
The increasing use of Computational Fluid Dynamics (CFD) for simulating blood flow in clinics demands the identification of appropriate patient‐specific boundary conditions for the customization of the mathematical models. These conditions should ideally be retrieved from measurements. However, finite resolution of devices as well as other practica...
Article
Although Thoracic EndoVascular Aortic Repair (TEVAR) is a consolidated procedure to treat thoracic aortic diseases, it still has relevant complications mainly related to suboptimal wall apposition of the stent-graft, impairing the post-operative hemodynamics and the clinical outcomes. Accurate stent-graft sizing and patient selection are the key as...
Article
Full-text available
Isogeometric collocation is for the first time considered as a simulation tool for fluid-saturated porous media. Accordingly, with a focus on one-dimensional problems, a mixed collocation approach is proposed and tested in demanding situations, on both quasi-static and dynamic benchmarks. The developed method is proven to be very effective in terms...
Chapter
The investigation of aortic hemodynamics in physiological and pathological conditions by computational fluid dynamics is still one of the major topic of vascular biomechanics. In particular, thanks to the developments of new endovascular technologies such as Thoracic EndoVAscular Repair (TEVAR), a lot of attention is paid to the hemodynamics analys...
Article
Aneurysms of the ascending aorta (AsAA), i.e., a progressive and localized dilatation of the first part of the aorta, represent a severe life-threatening condition, often occurring with no symptom. AsAA formation is associated with a degeneration of the aortic wall tissue, which leads to changes in the tissue mechanical properties, and in particula...
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Full-text available
Computer-based simulations are nowadays widely exploited for the prediction of the mechanical behavior of different biomedical devices. In this aspect, structural finite element analyses (FEA) are currently the preferred computational tool to evaluate the stent response under bending. This work aims at developing a computational framework based on...
Article
One of the main properties of cardiovascular stents is to properly bend in order to accommodate the tortuous vascular structure and Finite Element Analyses (FEA) are currently the preferred computational tool to properly evaluate the stent response under bending. Isogeometric Analysis (IgA) has recently emerged as a cost-effective alternative to cl...
Article
Transcatheter aortic valve implantation (TAVI) is a minimally invasive procedure introduced to treat aortic valve stenosis in elder patients. Its clinical outcomes are strictly related to patient selection, operator skills, and dedicated pre-procedural planning based on accurate medical imaging analysis. The goal of this work is to define a finite...
Article
Full-text available
The purpose of this study is to quantitatively evaluate the impact of endovascular repair on aortic hemodynamics. The study addresses the assessment of post-operative hemodynamic conditions of a real clinical case through patient-specific analysis, combining accurate medical image analysis and advanced computational fluid-dynamics (CFD). Although t...
Article
The gold standard for the study of the macro-anatomy of the aortic root are multi-detector computed tomography (MDCT) and magnetic resonance (MR) imaging. Both technologies have major advantages and limitations. Although 4D echo is entering the study of the aortic root, 2D echo is the most commonly used diagnostic tool in daily practice. We designe...
Article
The main key performance factors of honeycombs are represented by the ability to withstand through-thickness compression and to absorb energy by plastic deformation of the cell walls. The knowledge of the constituent material properties, including the sensitivity of these structures to material defects, and of the folding mechanism occurring during...
Article
Finite element analysis is nowadays a well-assessed technique to investigate the impact of stenting on vessel wall and, given the rapid progression of both medical imaging techniques and computational methods, the challenge of using the simulation of carotid artery stenting as procedure planning tool to support the clinical practice can be approach...
Conference Paper
The use of SMA is becoming more and more popular for both reusable and disposable biomedical devices especially for minimally-invasive cardiovascular procedures. In this scenario, the design of innovative devices able to combine the peculiar SMA material features with the clinical requirements is certainly challenge and calls for dedicated engineer...
Article
Full-text available
Until recently, heart valve failure has been treated adopting open-heart surgical techniques and cardiopulmonary bypass. However, over the last decade, minimally invasive procedures have been developed to avoid high risks associated with conventional open-chest valve replacement techniques. Such a recent and innovative procedure represents an optim...
Article
With the increase of life expectancy and population average age, heart valve diseases have become more frequent, representing an always increasing percentage among cardiovascular diseases, which are the predominant cause of death in the western country. For this reason, research activities within such a context and, in particular, computer-based pr...
Article
In some cases of aortic valve leaflet disease, the implant of a stentless biological prosthesis represents an excellent option for aortic valve replacement (AVR). In particular, if compared with the implant of mechanical valves, it provides a more physiological haemodynamic performance and a reduced thrombogeneticity, avoiding the use of anticoagul...
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Full-text available
Aortic valve-sparing (AVS) procedures have been introduced to treat ascending aorta dilatation and aortic valve insufficiency in the presence of preserved native aortic valve leaflets. Although the surgical technique has been standardized, the choice of best type and size of Dacron graft to be used remains a matter of debate. Herein are presented p...
Article
The use of shape memory alloys (SMA) in an increasing number of applications in many fields of engineering, and in particular in biomedical engineering, is leading to a growing interest toward an exhaustive modeling of their macroscopic behavior in order to construct reliable simulation tools for SMA devices. In this paper we review the properties...
Article
Full-text available
In this study, the shape memory effect of SMA beams under complex stress conditions is studied by means of a finite element model. The 1D version of a well-established SMA constitutive model is utilized in the numerical computations and the required parameters are obtained experimentally starting from thermal cycling tests in tension under differen...
Article
In some cases of aortic valve leaflet disease, the implant of a stentless biological prosthesis represents an excellent option for aortic valve replacement (AVR). In particular, if compared to more classical surgical approaches, it provides a more physiological hemodynamic performance and a minor trombogeneticity avoiding the use of anticoagulants....
Article
Full-text available
Sinotubular junction dilation is one of the most frequent pathologies associated with aortic root incompetence. Hence, we create a finite element model considering the whole root geometry; then, starting from healthy valve models and referring to measures of pathological valves reported in the literature, we reproduce the pathology of the aortic ro...
Article
The use of shape memory alloys (SMA) in an increasing number of applications in many fields of engineering, and in particular in biomedical engineering, is leading to a growing interest toward an exhaustive modeling of their macroscopic behavior in order to construct reliable simulation tools for SMA-based devices. In this paper, we review the prop...
Article
Full-text available
We present a measurement of the Cabibbo-Kobayashi-Maskawa matrix element |V(cb)| and the form-factor slope rho2 in B --> Dl- nu(l) decays based on 460x10(6) BB events recorded at the Upsilon(4S) resonance with the BABAR detector. B --> Dl- nu(l) decays are selected in events in which a hadronic decay of the second B meson is fully reconstructed. We...
Article
Full-text available
Searches for lepton-flavor-violating decays of a tau lepton to a lighter mass lepton and a photon have been performed with the entire data set of (963+/-7)x10{6} tau decays collected by the BABAR detector near the Upsilon(4S), Upsilon(3S) and Upsilon(2S) resonances. The searches yield no evidence of signals and we set upper limits on the branching...
Article
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A precise measurement of the cross section of the process e(+)e(-) --> pi(+)pi(-)(gamma) from threshold to an energy of 3 GeV is obtained with the initial state radiation (ISR) method using 232 fb(-1) of data collected with the BABAR detector at e(+)e(-) center-of-mass energies near 10.6 GeV. The ISR luminosity is determined from a study of the lep...
Article
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We search for invisible decays of the Upsilon(1S) meson using a sample of 91.4 x 10(6) Upsilon(3S) mesons collected at the BABAR/PEP-II B factory. We select events containing the decay Upsilon(3S) --> pi(+)pi(-)Upsilon(1S) and search for evidence of an undetectable Upsilon(1S) decay recoiling against the dipion system. We set an upper limit on the...
Article
We present evidence of D{0}-D[-over ]{0} mixing using a time-dependent amplitude analysis of the decay D{0}-->K+pi{-}pi;{0} in a data sample of 384 fb{-1} collected with the BABAR detector at the PEP-II e+e{-} collider at the Stanford Linear Accelerator Center. Assuming CP conservation, we measure the mixing parameters x{Kpipi{0}}{'}=[2.61{-0.68}{+...
Article
Full-text available
We present an analysis of the decays B{0}-->K{*0}(892)gamma and B{+}-->K{*+}(892)gamma using a sample of about 383 x 10{6} BB[-over ] events collected with the BABAR detector at the PEP-II asymmetric energy B factory. We measure the branching fractions B(B{0}-->K{*0}gamma)=(4.47+/-0.10+/-0.16) x 10{-5} and B(B{+}-->K{*+}gamma)=(4.22+/-0.14+/-0.16)...
Article
Full-text available
The unique features characterizing shape memory alloys (SMAs), such as superelasticity and shape memory effect, stimulate a deep investigation that aims at fully understanding their behavior through experimental tests. In the present work, we compare numerical results obtained using the phenomenological model proposed by Auricchio and Petrini in 20...
Article
Full-text available
The paper reports the first results of the Project WADI (Sustainability of European Irrigated Agriculture under Water Directive and Agenda 2000), funded under the 5th Framework Programme of the European Union (EU). The objective of the project is to evaluate the economic, social and environmental sustainability of European irrigated farming under d...
Article
A high sensitivity interferometer has been used to test the suspension of the Virgo interferometric antenna for gravitational wave search. Since Virgo is planning to enlarge the detection window down to 10 Hz, particular care is taken to improve the sensitivity in the low frequency region. Noise spectra are discussed. Between 20 and 100 Hz the limi...
Article
The mirrors of VIRGO, a proposed gravitational wave interferometer, must be aligned and locked onto an interference fringe. The special requirements of the force transducer lead us to the need for a coil system which has a very uniform magnetic field gradient. We describe the design, construction, and testing of a coil system which provides a magne...

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