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April 2021 - August 2023
Roche S.p.A
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- Collaborator
Publications
Publications (4)
In this work, we present a fast, globally convergent, iterative algorithm for computing the asymptotically stable states of nonlinear large-scale systems of quadratic autonomous ordinary differential equations (ODE) modeling, e.g., the dynamic of complex chemical reaction networks. Toward this aim, we reformulate the problem as a box-constrained op...
Introduction: Chemical reaction networks (CRNs) are powerful tools for describing the complex nature of cancer’s onset, progression, and therapy. The main reason for their effectiveness is in the fact that these networks can be rather naturally encoded as a dynamical system whose asymptotic solution mimics the proteins' concentration profile at equ...
Chemical reaction networks are powerful tools for computing the complex nature of cancer's onset, progression, and therapy. The main reason for their effectiveness is in the fact that these networks can be rather naturally encoded as a dynamical system whose asymptotic solution mimics the proteins' concentration profile at equilibrium. The paper re...
In this work we present a fast, globally convergent, iterative algorithm for computing the asymptotically stable states of nonlinear large--scale systems of quadratic autonomous Ordinary Differential Equations (ODEs) modeling, e.g., the dynamic of complex chemical reaction networks. Towards this aim, we reformulate the problem as a box--constrained...