Siddhartha Pati

Siddhartha Pati
NatNov Bioscience, Skills Innovation & Academic Network Institute

Ph.D. PDF
Exploring of biosources for small molecules, macromolecules & biochemical information to be used in scientific industry.

About

94
Publications
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Introduction
Dr. Siddhartha Pati working as Director at Natnov Bioscience and Association For BiodiversityConservation & Research. His international experience includes various programs, contributions and participation in different countries for study on Biotechnology, Marine Bioprospecting, Food Science, Biodiversity conservation.
Additional affiliations
January 2020 - January 2021
Universiti Malaysia Terengganu
Position
  • PostDoc Position
Education
April 2015 - May 2019

Publications

Publications (94)
Article
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Dairy cheese ball (Rasgulla) is one of the most commercially acclaimed dairy-based sweetmeat products in the Indian subcontinent. The main constrain with rasgulla export is the prediction of its shelf-life period, as there are several factors upon which the perishability of the product is dependent. Twenty-five nodes or concepts were chosen after a...
Research Proposal
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Climate is a phenomenon shaped by atmospheric, lithospheric and hydrosphere interaction and exhibits itself differently throughout the biosphere. Climate divides the earth into its various habitats e.g. tundra, temperate, tropical, etc. . For the largest water body, the ocean, the climate is responsible for events that take place in the photic and...
Research Proposal
Full-text available
About this special issue: The use of nanomaterials may help to improve the physiochemical stability of goods, distribute active substances, and improve their ultimate application. Nanomaterials have long piqued the interest of academics and scientists due to their exceptional qualities, which may be employed in a variety of fields. Recent advances...
Research Proposal
Full-text available
We are writing to invite you to contribute to the Special Issue on "Biopolymers for Enhanced Health Benefits" in International Journal of Molecular Sciences (IJMS—ISSN 1422-0067), We are pleased to share with you that the latest predicated *Impact Factor* of /IJMS/ would reach above 6.0 and has received the new Citescore 6.9. This Special Issue int...
Article
Antibiotics, used to treat human and animal diseases are often found ineffective due to rapidly increasing antibiotic resistance. Many of the acute and chronic diseases are caused by biofilm producing microbes. Since the emergence of antibiotic resistance throughout the world has been a point of concern some alternative therapeutic measure must be...
Research Proposal
Full-text available
Dear Researchers, We are approaching you with the request that we are in the process of editing a book entitled “Recent Frontiers of Phytochemicals: Applications in Food, Pharmacy, Cosmetics and Biotechnology”. The publisher is Elsevier Inc., Cambridge USA. You may kindly send your abstract to tanmay@wbscte.ac.in/ tanmays468@gmail.com with a tenta...
Article
Crime is a social problem faced by all communities and ranges from property loss or damage to violent events such as murder and robbery. Crime trends are associated with many factors including mental health, unemployment rates, educational status and policing strategies. In this article, we provide property crime datasets for Malaysia from 2007 to...
Article
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The seaweed industries generate considerable amounts of waste that must be appropriately managed. This biomass from marine waste is a rich source of high-value bioactive compounds. Thus, this waste can be adequately utilized by recovering the compounds for therapeutic purposes. Histone deacetylases (HDACs) are key epigenetic regulators established...
Article
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Microbial communities within fermented food (beers, wines, distillates, meats, fishes, cheeses, breads) products remain within biofilm and are embedded in a complex extracellular polymeric matrix that provides favorable growth conditions to the indwelling species. Biofilm acts as the best ecological niche for the residing microbes by providing food...
Article
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In recent times, the seafood industry is found to produce large volumes of waste products comprising shrimp shells, fish bones, fins, skins, intestines, and carcasses, along with the voluminous quantity of wastewater effluents. These seafood industry effluents contain large quantities of lipids, amino acids, proteins, polyunsaturated fatty acids, m...
Article
Biofilm‐associated infections have increased excessively over the recent years due to the increased population having impaired immune systems or as a result of certain medical conditions like transplantation, cancer, and any other chronic ailments. The abrupt enhancement of antibiotic resistance and enhanced utilization of biomedical devices offer...
Article
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Importance: The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. Objective: To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic...
Article
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Aegle marmelos is a sacred fruit with several medicinal properties, though availability is limited in a certain period of the year. It is therefore preserved in the form of leather through dehydration. In total, 16 concepts or nodes were selected after an interview with 27 stakeholders from different segments of food industries (packaging technolog...
Article
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The healing of chronic wound infections, especially cutaneous wounds, involves a complex cascade of events demanding mutual interaction between immunity and other natural host processes. Wound infections are caused by the consortia of microbial species that keep on proliferating and produce various types of virulence factors that cause the developm...
Article
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The chemical composition of any food material can be analyzed well by employing various an-alytical techniques. The physical properties of food are no less important than chemical compo-sition as results obtained from authentic measurement data are able to provide detailed infor-mation about the food. Several techniques have been used for years for...
Article
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The marine environment is a relatively unexplored source of functional ingredients that can be used in food processing, storage, and fortification in a variety of ways. Marine microorganisms are a possible source of novel bioactive chemicals with potential human utility. Some of these microbes can live in the harsh marine environments, resulting in...
Article
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Mango (Himsagar cultivar) is a high moisture-bearing seasonal fruit and cultivated in a wide range of the world. Mango pulp is generally preserved by sun drying. In recent days, industries are using hot-air oven, freeze, and microwave drying for mango leather (dried mango pulp in the sheet like texture) processing. Here, all these four drying metho...
Chapter
Anthropogenic activities influence the survival and reproduction of horseshoe crabs in their marine-associated habitats. On the northeast coast of Odisha, India, a large number of them die every year. The use of fishing gear has been identified as the major cause for their mortality. A total of 6546 specimens of entangled T. gigas were recorded in...
Research Proposal
Full-text available
This book mainly intends to highlight high-quality original research and review papers that include innovative bioactive compounds and cutting-edge characterization techniques that contribute significantly to the area of diverse potential applications.
Article
Fermented soy pulp (FSP) is currently capturing attention worldwide because of the high price of fish meal and its inconsistent supply in recent years. FSP replaces fish meal as a source of protein and energy towards improved fish health and growth. The protein replacement was employed in this study to assess the growth and health status, digestive...
Chapter
As a marine arthropod, horseshoe crab has persisted for more than 200 million years and is still enjoying its life on earth without much morphological modifications. Out of the four extant species, two species, namely Tachypleus gigas (Müller 1785) and Carcinoscorpius rotundicauda (Latreille 1802), are found along the northeast coast of Bay of Beng...
Chapter
The unregulated coastal land use in Pahang, East Coast of Peninsular Malaysia, has interfered with the landscape and natural hydrodynamic processes such as tides and currents. The river mouths of Balok and Pahang Tua have suffered from anthropic activities and resulted in the beach sediment morphology becoming unfavorable for horseshoe crab spawnin...
Article
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Leonurus sibiricus (Red verticilla, honeyweed) is a type of herbaceous plant predominantly found in Asian subcontinents as weed in crop fields and is widely used for treating diabetes, bronchitis, and menstrual irregularities. However, there is a dearth of study in the application of the plant phytocompounds for treating biofilm-associated chronic...
Article
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Increased resistance of Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter sp. (ESKAPE) pathogens against various drugs has enhanced the urge for the development of alternate therapeutics. Quorum sensing (QS) is a density dependent cell-to-cell communication mechanis...
Article
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Background In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15–39 years) are lacking. To address this...
Article
The crisis in worldwide health sectors due to rapidly growing enhancement in the antibiotic resistance of bacterial species has resulted in the search for alternate therapeutics. Since often such resistance is attributed to the biofilm matrix synthesized by bacterial cells, a search is being made to explore new compounds with easy permeability. The...
Article
Mangoes are rich in vitamins, carotenes, organic acids and minerals. Sun, convective, microwave, and freeze-drying have been adopted for mango leather processing. Raw mango pulp (RMP) was found superior in vitamin A (1.52±0.06 mg/100g) and ascorbic acid (41.58±1.36 mg/100g) content. Vitamin D was not detected in the raw or dried product. Citric aci...
Article
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Major population in the Boudh district of Odisha, India basically depends upon groundwater for various household needs. The presence of underlying hard-rock terrain increases the scarcity, and fluoride content in the groundwater. Hydrochemical studies have been conducted to evaluate the quality of groundwater using GIS. A field reconnaissance surve...
Article
Full-text available
Exosomes being non-ionized micro-vesicles with a size range of 30–100 nm possess the ability to bring about intracellular communication and intercellular transport of various types of cellular components like miRNA, mRNA, DNA, and proteins. This is achieved through the targeted transmission of various inclusions to nearby or distant tissues. This i...
Article
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Bacterial cellulose (BC) is recognized as a multifaceted, versatile biomaterial with abundant applications. Groups of microorganisms such as bacteria are accountable for BC synthesis through static or agitated fermentation processes in the presence of competent media. In comparison to static cultivation, agitated cultivation provides the maximum yi...
Article
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Brain cancers, mainly high-grade gliomas/glioblastoma, are characterized by uncontrolled proliferation and recurrence with an extremely poor prognosis. Despite various conventional treatment strategies, viz., resection, chemotherapy, and radiotherapy, the outcomes are still inefficient against glioblastoma. The blood–brain barrier is one of the maj...
Article
Urinary tract infection (UTI) is one of the most common bacterial infections in humans, which are gradually becoming resistant to currently available therapies. Bacterial biofilms, an aggregate of microorganisms, are mainly responsible for persistent infections leading to recurrences and increased tolerances to major drug treatment. Bacterial biofi...
Article
The development of plant ingredients as an alternative to fish meal (FM) has received sustained interest in the aquaculture sector. The study investigated the replacement of FM with different percentages of dietary fermented soy pulp (FSP) to assess the growth performance, haematology, blood biochemical, liver, and gut morphology of African catfish...
Article
Full-text available
Although horseshoe crabs have ecological and biomedical value, their restricted distribution in the northeast coast (Odisha, West Bengal) to a limited number of researchers have made them an understudied arthropod in India. With an objective that uses ‘desktop review’ for horseshoe crab ecology, biology and their life cycle in India, it is learnt t...
Article
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Gold nanoparticles (AuNPs) have been widely explored and are well-known for their medical applications. Chemical and physical synthesis methods are a way to make AuNPs. In any case, the hunt for other more ecologically friendly and cost-effective large-scale technologies, such as environmentally friendly biological processes known as green synthesi...
Article
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COVID-19 is a disease that puts most of the world on lockdown and the search for therapeutic drugs is still ongoing. Therefore, this study used in silico screening to identify natural bioactive compounds from fruits, herbaceous plants, and marine invertebrates that are able to inhibit protease activity in SARS-CoV-2 (PDB: 6LU7). We have used extens...
Article
Contamination of food products with microorganisms from various sources is a serious concern as it not only affects the food quality also leads to spoilage and therefore may cause several illnesses. Chemical preservatives may not be considered as a potential way as it has many disadvantages. The use of bio-preservatives can replace it. Bacteriocins...
Article
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The application of coal ash (CA) in construction industries has grown rapidly, posing risk to the environment due to heavy metals leaching from the material. This research presents a simulation of ecological risk assessment and model risk indicators (ERI) of leached heavy metals (lead (Pb), copper (Cu), zinc (Zn) and arsenic (As)) from CA (FA: fly...
Research Proposal
Full-text available
Call for Papers- Frontiers in Marine Science/Marine Biotechnology Research Topic: High Throughput Omics Technologies for Understanding Molecular Stress Response and Devising Mitigation Actions About this Research Topic: The oceans act as the ultimate sinks for a wide range of anthropogenic and natural pollutants, which act as stressors for the orga...
Cover Page
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Dear Researchers/Colleagues, As per your expertise, it is our pleasure to invite you to contribute your paper for the Special Issue: Recent advances on Potential Bioactive compounds and their Biotechnological application to be published in Applied Biochemistry and Biotechnology, Springer, with Impact factor- 2.92. The purpose of this Special Issue...
Article
The release of petroleum and petroleum derivatives, such as polycyclic aromatic hydrocarbons (PAHs), in the environment owing to anthropogenic activities, has become a major global threat to human health and ecological equilibrium. It causes a number of diseases and petroleum hydrocarbon (PH) compounds bind to soil components, making their removal...
Article
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The green synthesis of silver nanoparticles (AgNPs) has currently been gaining wide applications in the medical field of nanomedicine. Green synthesis is one of the most effective procedures for the production of AgNPs. The Diospyros malabarica tree grown throughout India has been reported to have antioxidant and various therapeutic applications. I...
Article
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Freshwater supply is critical for domestic, agriculture and industrial purposes. A good supply of clean water is normally obtained from surface and groundwater water bodies. Nonetheless, many localities rely heavily on the later as the main source of their water resource. Therefore, proper mapping, exploitation and conservation of groundwater resou...
Article
Full-text available
The biggest challenge in the present-day healthcare scenario is the rapid emergence and spread of antimicrobial resistance due to the rampant use of antibiotics in daily therapeutics. Such drug resistance is associated with the enhancement of microbial virulence and the acquisition of the ability to evade the host's immune response under the shelte...
Article
Full-text available
DNA profiling of X-chromosomal short tandem repeats (X-STR) has exceptional value in criminal investigations, especially for complex kinship and incest cases. In this study, Investigator® Argus X-12 Quality Sensor (QS) kits were successfully used to characterize 12 X-STR loci in 199 unrelated healthy Kedayan individuals living in Sabah and Sarawak,...
Article
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Introduction: Hereditary hemochromatosis (HH) is an autosomal recessive disorder that causes accumulation of iron in circulating blood and organs. The disease is associated with H63D, S65C and C282Y variants of the haemo-chromatosis (HFE) gene and, if not treated can cause organ damage and may prove fatal. The main objectives of the present survey...
Article
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The capacity of organisms to change their sex has evolved independently in several species. Sex change has been widely studied, but research approaches have differed and conclusions have often been specific. Although sex allocation theory provides a unifying framework for the study of sex change, this unity has not always been appreciated, Environm...
Article
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Bacterial biofilms are responsible for the development of various chronic wound related and implant mediated infections and confer protection to the pathogenic bacteria against antimicrobial drugs and host immune responses. Hence biofilm mediated chronic infections have created tremendous burden upon health care systems worldwide. The development o...
Article
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The γ-irradiated horseshoe crab chitosan was used as food coating to extend the shelf life of marine shrimp and fish. Fourier-transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FE-SEM), and X-ray diffraction (XRD) were used to characterize the γ-irradiated chitosan. After employing control (untreated seafood sample...
Article
Full-text available
Biofilm is a syntrophic association of sessile groups of microbial cells that adhere to biotic and abiotic surfaces with the help of pili and extracellular polymeric substances (EPS). EPSs also prevent penetration of antimicrobials/antibiotics into the sessile groups of cells. Hence, methods and agents to avoid or remove biofilms are urgently neede...
Article
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Diosgenin encapsulated PCL-Pluronic nanoparticles (PCL-F68-D-NPs) have been developed by nanoprecipitation method to improve the performance in brain cancer (glioblastoma) therapy. The nano-particles were characterized by DLS/Zeta potential, FTIR, XRD, FESEM and TEM. The encapsulation efficiency, loading efficiency and yield were calculated. The in...
Article
Full-text available
Bacteria are considered as the major cell factories which can effectively convert nitrogen and carbon sources to a wide variety of extracellular and intracellular biopolymers like polyamides, polysaccharides, polyphosphates, polyesters, proteineceous compounds and extracellular DNA. Bacterial biopolymers find applications in pathogenicity and their...
Article
Full-text available
Horseshoe crabs (Tachypleus tridentatus) are arthropods that restrict their distributions to natal vicinities. Briefly, shore perturbation from boating (Kudat), electric, cyanide and bombing (Kunak) and tourism (Semporna) in Sabah can impair the T. tridentatus growth and produce sexually mature adults with unusual size. The 8-point morphometry of T...
Preprint
p>Corona viruses were first identified in 1931 and SARS-CoV-2 is the most recent. COVID-19 is a pandemic that put most of the world on lockdown and the search for therapeutic drugs is still on-going. Therefore, this study uses in silico screening to identify natural bioactive compounds from fruits, herbaceous plants and marine invertebrates that ar...
Preprint
First report Macrolactin A could be an effective therapeutical agent for SARS-CoV-2protease (6LU7) inhibition.
Article
Full-text available
Emergence of bacterial resistance to antibiotics has led to the search for alternate antimicrobial treatment strategies. Engineered nanoparticles (NPs) for efficient penetration within the living system became more common in the world of health and hygiene. The use of microbial enzymes/proteins as a potential reducing agent for synthesizing NPs has...
Article
Being a seasonal fruit mango cannot be cherished over the year; dehydration may be a solution to preserve the deliquesce of mango as mango leather. The processing parameters like puree load (0.4-0.6 g/cm 2), total soluble solid (20-30°B), oven temperature (60-80°C), and microwave power level (100-300 W) were optimised for a superior tex-tural attri...