Shuntaro Yamada

Shuntaro Yamada
University of Bergen | UiB · Department of Clinical Dentistry

D.D.S., M.Sc.
Mechanical induction of osteogenesis and signal transduction targeting Rho/ROCK pathway

About

8
Publications
1,845
Reads
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51
Citations
Citations since 2016
8 Research Items
52 Citations
20162017201820192020202120220510152025
20162017201820192020202120220510152025
20162017201820192020202120220510152025
20162017201820192020202120220510152025
Introduction
Shuntaro Yamada is a Ph.D candidate at the department of Clinical Dentistry, the University of Bergen. He does research on signal transduction of mesenchymal stem cells by focusing on cytoskeltal regulation under dynamic culture condition.A previous work was on epithelial invagination during tooth morphogenesis.
Additional affiliations
November 2018 - October 2022
University of Bergen
Position
  • PhD Student
June 2017 - December 2018
King's College London
Position
  • Master's Student
Description
  • Investigation of tooth morphogenesis from mechanobiological aspects by means of advanced microscopy, image analyses and explant culture. Thesis Title: Mechano-biological regulation for cervical loop formation during tooth morphogenesis
March 2016 - October 2016
Malmö University
Position
  • Visiting research student (MClinSc)
Description
  • The investigation of bone formation/resorption around dental implant having different characteristics
Education
November 2018 - October 2022
University of Bergen
Field of study
  • Bone Tissue Engineering
June 2017 - September 2018
King's College London
Field of study
  • Regenerative Dentistry
April 2007 - March 2013
Kanagawa Dental University
Field of study
  • Clinical Dentistry

Publications

Publications (8)
Article
Full-text available
Tooth germs undergo a series of dynamic morphologic changes through bud, cap, and bell stages, in which odontogenic epithelium continuously extends into the underlying mesenchyme. During the transition from the bud stage to the cap stage, the base of the bud flattens and then bends into a cap shape whose edges are referred to as “cervical loops.” A...
Article
Full-text available
Various types of synthetic polyesters have been developed as biomaterials for tissue engineering. These materials commonly possess biodegradability, biocompatibility, and formability, which are preferable properties for bone regeneration. The major challenge of using synthetic polyesters is the result of low cell affinity due to their hydrophobic n...
Article
Full-text available
The fatal determination of bone marrow mesenchymal stem/stromal cells (BMSC) is closely associated with mechano-environmental factors in addition to biochemical clues. The aim of this study was to induce osteogenesis in the absence of chemical stimuli using a custom-designed laminar flow bioreactor. BMSC were seeded onto synthetic microporous scaff...
Article
Full-text available
Key points •Periodontal regeneration requires the hierarchical reorganization of soft and hard tissues, namely, periodontal ligament, cementum, alveolar bone, and gingiva. •Three-dimensional microporous scaffolds offer structural support and spatiotemporal guidance for cell growth and differentiation. •Biomimetic periodontal extracellular matrix sc...
Article
Full-text available
Various perfusion bioreactor systems have been designed to improve cell culture with three-dimensional porous scaffolds, and there is some evidence that fluid force improves the osteogenic commitment of the progenitors. However, because of the unique design concept and operational configuration of each study, the experimental setups of perfusion bi...
Article
Full-text available
Degradable polyester-based scaffolds are ideal for tissue engineering applications where long-term structural integrity and mechanical support are a requisite. However, their hydrophobic and unfunctionalized surfaces restrain their tissue-mimetic quality. Instead, hyaluronan (HA) hydrogels are able to act as cell-instructive materials with the abil...
Article
Full-text available
Three-dimensional printing (3D printing) is a promising technique for producing scaffolds for bone tissue engineering applications. Porous scaffolds can be printed directly, and the design, shape and porosity can be controlled. 3D synthetic biodegradable polymeric scaffolds intended for in situ bone regeneration must meet stringent criteria, primar...
Article
Full-text available
This study investigated the level of magnetic energy around implants possessing a static magnetic field (SMF) and assessed the in vivo influence of SMF on bone regeneration. Implants possessing a sintered neodymium magnet internally were placed in a rabbit femur. An implant without SMF was placed as control. After 12 weeks of healing in vivo, the b...

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Projects

Project (1)
Project
The aim of the project is to investigate the effects of physical stress on mesenchymal stem cells for bone tissue engineering.