Shuen Hsin Liu

Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare · Department of internal medicine, division of cardiology

Purpose: Ventricular arrhythmia (VA) is related to inflammatory activity. Rhodiola crenulate (RC) and its main active component, salidroside, have been reported as anti-inflammatory agents. The aim of this study was to demonstrate the effect of RC and salidroside in preventing VA via the inhibition of IL-17 in an ischemic heart failure (HF) model....

Background: We aimed to investigate the impact of interleukin (IL)-17 on ventricular remodeling and the genesis of ventricular arrhythmia (VA) in an ischemic heart failure (HF) model. The expression of the proinflammatory cytokine IL-17 is upregulated during myocardial ischemia and plays a fundamental role in postinfarct inflammation. However, the...

Introduction: Rhodiola, a popular plant in Tibet, has been proven to decrease arrhythmia. The aim of this study was to elucidate the molecular mechanism and electrophysiological properties of Rhodiola in the suppression of atrial fibrillation. Methods: This study consisted of 3 groups as follows: Group 1: normal control rabbits (n = 5); Group 2:...

Resveratrol has shown benefits in reducing ventricular remodeling and arrhythmias. This study aimed to assess the therapeutic efficacy of resveratrol in reducing atrial fibrillation (AF) in a heart failure (HF) model and explore underlying mechanisms. HF rabbits were created 4 weeks after undergoing coronary ligation. Group 1 (n = 6) included (a) n...

Background: This study aimed to investigate the mechanism by which colchicine suppresses atrial fibrillation (AF) in a rabbit heart failure (HF) model. Methods and results: HF was induced by coronary ligation. Using the Langendorff perfusion system, monophasic action potentials were recorded in the left atrial appendage (LAA) of normal rabbits (...

The atrial substrate in chronic atrial fibrillation (AF) patients with a left atrial spontaneous echo contrast (LASEC) has not been previously reported. The aim of this study was to investigate the atrial substrate properties and long-term follow-up results in the patients who received catheter ablation of chronic AF. Of 36 consecutive patients wit...

It is difficult to discriminate patients with and without paroxysmal atrial fibrillation (PAF). The atrial electromechanical interval determined by the transthoracic echocardiogram is demonstrated to be a predictor of new onset AF. The aim of our study was to investigate whether the electromechanical interval is a useful parameter to identify patie...

The CHADS₂ score (congestive heart failure, hypertension, age >75 years, diabetes, and previous stroke/transient ischemic attack) is used for the risk stratification of strokes in patients with atrial fibrillation (AF). This study aimed to investigate the associations between the CHADS₂ score, atrial substrate, and outcome of catheter ablation in p...

Case Presentation A 30-year-old man with antidromic AVRT had received transcatheter ablation of left posterolateral accessory pathway twice before, but it was recurred again. He was referred to our laboratory for further ablation. At our laboratory, antegrade accessory pathway could be manifested during atrial extrastimuli at 500/250 msec with the...