Shu-Chen Li

Shu-Chen Li
Technische Universität Dresden (TU Dresden) · Psychology and Centre for Tactile Internet with Human-in-the-Loop

Ph.D.

About

264
Publications
46,019
Reads
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15,381
Citations
Citations since 2017
82 Research Items
6801 Citations
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Introduction
Shu-Chen Li currently works at the Faculty of Psychology and Centre for Tactile Internet with Human-in-the-Loop (CeTI), Technische Universität Dresden (TU Dresden). TU Dresden is one of the 11 Excellence universities in Germany. Shu-Chen Li holds the Chair of Lifespan Developmental Neuroscience (https://tu-dresden.de/mn/psychologie/ipep/epsy) in Psychology and is a PI and one of the co-speakers of the research center CeTI (https://www.ceti.one/).
Additional affiliations
October 2012 - present
Technische Universität Dresden
Position
  • Prof. of Lifespan Developmental Neuroscience
January 2001 - August 2012
Max Planck Institute for Human Development
Position
  • Research Scientist/Project Leader

Publications

Publications (264)
Article
Full-text available
Gait recognition is the process of identifying humans from their bipedal locomotion such as walking or running. As such, gait data is privacy sensitive information and should be anonymized where possible. With the rise of higher quality gait recording techniques, such as depth cameras or motion capture suits, an increasing amount of detailed gait d...
Article
Full-text available
How congruence cues and congruence-based expectations may together shape perception in virtual reality (VR) still need to be unravelled. We linked the concept of plausibility used in VR research with congruence-based modulation by assessing brain responses while participants experienced vehicle riding experiences in VR scenarios. Perceptual plausib...
Article
Full-text available
Previous studies indicate a role of dopamine in spatial navigation. Although neural representations of direction are an important aspect of spatial cognition, it is not well understood whether dopamine directly affects these representations, or only impacts other aspects of spatial brain function. Moreover, both dopamine and spatial cognition decli...
Preprint
Full-text available
Forward planning is crucial to maximize outcome in complex sequential decision-making scenarios. In this cross-sectional study, we were particularly interested in age-related differences of forward planning. We presumed that especially older individuals would show a shorter planning depth to keep the costs of modelbased decision-making within limit...
Article
Full-text available
Empirical evidence has shown that visually enhancing the saliency of reward probabilities can ease the cognitive demands of value comparisons and improve value-based decisions in old age. In the present study, we used a time-varying drift diffusion model that includes starting time parameters to better understand (1) how increasing the saliency of...
Article
Full-text available
We recently showed that incentive motivation improves the precision of the Approximate Number System (ANS) in young adults. To shed light on the development of incentive motivation, the present study investigated whether this effect and its underlying mechanisms may also be observed in younger samples. Specifically, seven-year-old children (n = 23;...
Article
Under high cognitive demands, older adults tend to resort to simpler, habitual, or model-free decision strategies. This age-related shift in decision behavior has been attributed to deficits in the representation of the cognitive maps, or state spaces, necessary for more complex model-based decision-making. Yet, the neural mechanisms behind this sh...
Preprint
Full-text available
Gait recognition is the process of identifying humans from their bipedal locomotion such as walking or running. As such gait data is privacy sensitive information and should be anonymized. With the rise of more and higher quality gait recording techniques, such as depth cameras or motion capture suits, an increasing amount of high-quality gait data...
Article
Full-text available
While the importance of social affect and cognition is indisputable throughout the adult lifespan, findings of how empathy and prosociality develop and interact across adulthood are mixed and real-life data are scarce. Research using ecological momentary assessment recently demonstrated that adults commonly experience empathy in daily life. Further...
Article
Full-text available
Introduction: Given rapid global population aging, developing interventions against age-associated cognitive decline is an important medical and societal goal. We evaluated a cognitive training protocol combined with transcranial direct current stimulation (tDCS) on trained and non-trained functions in non-demented older adults. Methods: Fifty-s...
Article
Full-text available
Antenatal synthetic glucocorticoid (sGC) treatment is a potent modifier of the hypothalamic-pituitary-adrenal (HPA) axis. In this context, epigenetic modifications are discussed as potential regulators explaining how prenatal exposure to GCs might translate into persistent changes of HPA axis “functioning”. The purpose of this study was to investig...
Article
Full-text available
In the early 2020s, the coronavirus pandemic brought the notion of remotely connected care to the general population across the globe. Oftentimes, the timely provisioning of access to and the implementation of affordable care are drivers behind tele-healthcare initiatives. Tele-healthcare has already garnered significant momentum in research and im...
Article
Brain aging at the neurochemical, anatomical, and functional levels has direct implications for various cognitive, motivational, and affective functions in old age. With global population demographics heading towards a faster-growing trend in the population aged 60 and above than all other age groups, the task to maintain and enhance cognitive, mot...
Article
This chapter presents an overview of the recent findings from the World Health Organization World Mental Health Surveys Initiative. Many consistent patterns of association emerge in all countries: mental disorders begin relatively early in the lifespan; they are most prevalent among the young and the socially disadvantaged; they are often highly im...
Article
This handbook is currently in development, with individual articles publishing online in advance of print publication. At this time, we cannot add information about unpublished articles in this handbook, however the table of contents will continue to grow as additional articles pass through the review process and are added to the site. Please note...
Article
Full-text available
The abilities to monitor one’s actions and novel information in the environment are crucial for behavioural and cognitive control. This study investigated the development of error and novelty monitoring and their electrophysiological correlates by using a combined flanker with novelty-oddball task in children (7–12 years) and adolescents (14–18 yea...
Article
Full-text available
The ability to perceive differences in depth is important in many daily life situations. It is also of relevance in laparoscopic surgical procedures that require the extrapolation of three-dimensional visual information from two-dimensional planar images. Besides visual-motor coordination, laparoscopic skills and binocular depth perception are dema...
Article
Full-text available
Anticipating population ageing to reach a historically unprecedented level in this century and considering the public goal of promoting well-being until old age, research in many fields has started to focus on processes and factors that contribute to healthy ageing. Since human interactions have a tremendous impact on our mental and physical well-b...
Preprint
While the importance of social affect and cognition is indisputable throughout the adult lifespan, findings of how empathy and prosociality develop and interact across adulthood are mixed, and real-life data are scarce. Research using ecological momentary assessment recently demonstrated that adults commonly experience empathy in daily life. Furthe...
Preprint
Full-text available
While the importance of social affect and cognition is indisputable throughout the adult lifespan, findings of how empathy and prosociality develop and interact across adulthood are mixed, and real-life data are scarce. Research using ecological momentary assessment recently demonstrated that adults commonly experience empathy in daily life. Furthe...
Preprint
Full-text available
Previous studies indicate a role of dopamine in hippocampus-dependent spatial navigation. Although neural representations of direction are an important aspect of spatial cognition, it is not well understood whether dopamine directly affects these representations, or only impacts other aspects of spatial brain function. Moreover, both dopamine and s...
Article
Full-text available
Spatial learning can be based on intramaze cues and environmental boundaries. These processes are predominantly subserved by striatal- and hippocampal-dependent circuitries, respectively. Maturation and aging processes in these brain regions may affect lifespan differences in their contributions to spatial learning. We independently manipulated an...
Article
Full-text available
Numerous technological solutions have been proposed to promote piano learning and teaching, but very few with market success. We are convinced that users’ needs should be the starting point for an effective and transdisciplinary development process of piano-related Tactile Internet with Human-in-the-Loop (TaHIL) applications. Thus, we propose to in...
Article
Full-text available
Humans differ in their capacity for integrating perceived events and related actions. The “Theory of event coding” (TEC) conceptualizes how stimuli and actions are cognitively bound into a common functional representation (or “code”), known as the “event file”. To date, however, the neural processes underlying the development of event file coding m...
Preprint
Empirical evidence has shown that visually enhancing the saliency of reward probability information can ease the cognitive demands of value comparisons and improve value-based decision-making in old age. In the present study, we used a time-varying DDM that includes starting time parameters (henceforth starting time DDM, stDDM) to better understand...
Article
Full-text available
We present a comprehensive scheme for the quality assessment of compressed vibrotactile signals with human assessors. Inspired by the multiple stimulus test with hidden reference and anchors (MUSHRA) from the audio domain, we designed a method in which each compressed signal is compared to its original signal and rated on a numerical scale. For eac...
Article
Full-text available
When under high cognitive demand older adults tend to resort to simpler, model-free decision strategies. This age-related shift in decision behaviour has been attributed to deficits in the representation of the cognitive maps, or state spaces, necessary for more complex model-based decision-making. Yet, the neural mechanism behind this shift remain...
Article
Full-text available
Background Gilles de la Tourette Syndrome (GTS) is a neurodevelopmental disorder with a peak of symptom severity around late childhood and early adolescence. Previous findings in adult GTS suggest that changes in perception-action integration, as conceptualized in the Theory of Event Coding (TEC) framework, are central for the understanding of GTS....
Article
Performing a goal-directed movement consists of a chain of complex preparatory mechanisms. Such planning requires especially integration (or binding) of various action features, a process that has been conceptualized in the “Theory of Event Coding”. Theoretical considerations and empirical research suggest that these processes are subject to develo...
Article
Full-text available
The ability to learn sequential contingencies of actions for predicting future outcomes is indispensable for flexible behavior in many daily decision-making contexts. It remains open whether such ability may be enhanced by transcranial direct current stimulation (tDCS). The present study combined tDCS with functional near-infrared spectroscopy (fNI...
Article
Decoding others’ intentions accurately in order to adapt one's own behavior is pivotal throughout life. In this study, we asked how younger and older adults deal with uncertainty in dynamic social environments. We used an advice-taking paradigm together with Bayesian modelling to characterize effects of aging on learning about others’ time-varying...
Chapter
The emerging new field of research on Tactile Internet with Human-in-the-Loop (TaHiL) aims to achieve significant breakthroughs to enhance collaborations between humans and machines or—more generally, Cyber-Physical System (CPS)—in real, virtual, and remote environments. The vision of TaHiL is to enable humans to interact with cooperating CPS over...
Chapter
Humans interact with the environments through their senses. Since Helmholtz's classical concept, it is well known in psychology and cognitive neuroscience that human perception and action are influenced by an individual's prior sensory and learning experiences, as well as by other factors, such as task-specific goals or contexts. Focusing on human...
Chapter
This chapter discusses the state of the art and current investigations by the authors in the field of perceptual haptic coding. The discussion covers both kinesthetic and tactile codecs, which take different types of input and target different objectives. Kinesthetic codecs are designed to reduce the number of packets to be exchanged bidirectionall...
Article
Perceptual decisions entail the accumulation of evidence until a decision criterion is reached. The amount of noise in this process is inversely related to the behavioral performance of the decision-maker. Hence, reducing the amount of perceived noise could improve performance in perceptual decisions. In this study, we investigated whether providin...
Article
Research on non‐invasive methods of modulating age‐associated cognitive decline has yielded promising results. Current evidence shows that transcranial direct current stimulation (tDCS), if administered with concurrent cognitive training, may successfully modulate cognitive performance. In the TrainStim‐Cog trial, we investigated in healthy older a...
Article
Aging attenuates frontostriatal network functioning, which could lead to deficits in value computation when decision-making involves uncertainty. Although it has been shown that visually enhancing information saliency of outcome probability can improve decision-making in old age, mechanisms of this effect are still unclear. In the present study, th...
Article
Full-text available
Background Given the growing older population worldwide, and the associated increase in age-related diseases, such as Alzheimer’s disease (AD), investigating non-invasive methods to ameliorate or even prevent cognitive decline in prodromal AD is highly relevant. Previous studies suggest transcranial direct current stimulation (tDCS) to be an effect...
Preprint
Full-text available
Learning is pervasive across the human lifespan and essential for adaptive behavior. Children and older adults are often slower to learn cognitive tasks than young adults. Here we build on established theory formalizing learning as predictive inference and consider the possibility that age-related learning differences emerge from satisficing in thi...
Preprint
Across the lifespan, humans rely on the ability to learn from new experiences to adapt to uncertain and changing environments. Here we investigated age-related differences in the reliance on default-belief settings during learning in these environments. We collected behavioral data with a predictive-inference task in children, adolescents as well a...
Article
Hippocampal and striatal circuits play important roles in spatial navigation. These regions integrate environmental information and receive intrinsic afferent inputs from the vestibular system. Past research indicates that galvanic vestibular stimulation (GVs) is a non-invasive technique that modulates hippocampal and striatal activities. There are...
Article
A comprehensive understanding of the basic molecular and cellular mechanisms of the brain is important for the scientific discovery of root causes, risk and protective factors for mental disorders in global mental health. Systematic research in cultural neuroscience within the research domain criteria (RDoC) framework investigates the fundamental b...
Article
Full-text available
The error-related negativity (ERN/Ne) as well as the early and late error positivity (Pe) are electrophysiological correlates known to reflect error detection and error awareness. Despite much evidence on age differences in mastering response conflicts, the development and the functional distinctiveness of these components across the lifespan is st...
Article
Attentional control is crucial for selectively attending to relevant information when our brain is confronted with a multitude of sensory signals. Graph-theoretical measures provide a powerful tool for investigating the efficiency of brain network communication in separating and integrating information. Albeit it has been demonstrated that atDCS ca...
Article
Full-text available
Recent studies show that training the approximate number system (ANS) holds promise for improving symbolic math abilities. Extending this line of research, the present study aims to shed light on incentive motivation of numerosity discrimination and the underlying mechanisms. Thirty-two young adults performed a novel incentivized dot comparison tas...
Article
Human aging is characterized by impaired spatial cognition and reductions in the distinctiveness of category-specific fMRI activation patterns. Yet, little is known about age-related decline in neural distinctiveness of information that humans use when navigating spatial environments. Here, we asked whether neural tuning functions of walking direct...
Article
The relationship between tics and preceding urges in Tourette syndrome suggests that abnormal internal monitoring is reflected in abnormal perceptual, attentional, and response selection. This article uses the theory of event coding to conceptualize Tourette syndrome as a disorder of the integration of perception and action. Given that Tourette syn...
Article
Context: Antenatal synthetic glucocorticoid (sGC) treatment constitutes a potent programming factor of the hypothalamic-pituitary-adrenal (HPA) axis. Previous findings from our group revealed long-term changes in cortisol stress reactivity following antenatal sGC therapy. However, the few prior studies exclusively relied on spot measurements of ph...
Preprint
Full-text available
Human aging is characterized by impaired spatial cognition and reductions in the distinctiveness of category-specific fMRI activation patterns. Yet, little is know about age-related decline in neural distinctiveness of spatial information. Here, we asked whether neural tuning functions of walking direction are broadened in older versus younger adul...
Article
Full-text available
Background With increasing aging populations worldwide, developing interventions against age-associated cognitive decline is particularly important. Evidence suggests that combination of brain stimulation with cognitive training intervention may enhance training effects in terms of performance gain or transfer to untrained domains. This protocol de...
Poster
Full-text available
Younger adults' decision-making behavior is often a combination of model-free (MF) and model-based (MB) decision strategies. In contrast, older adults seem to primarily rely on MF strategies. This age-related shift in decision strategies has been interpreted in terms of a deficit in the representation of transition structures necessary for MB decis...
Article
Full-text available
Hippocampal and striatal circuits play important roles in spatial navigation. These regions integrate environmental information and receive intrinsic afferent inputs from the vestibular system. Past research indicates that galvanic vestibular stimulation (GVS) is a non-invasive technique that modulates hippocampal and striatal activities. There are...
Article
Full-text available
Aging and dopamine modulation have both been independently shown to influence the functional connectivity of brain networks during rest. Dopamine modulation is known to decline during the course of aging. Previous evidence also shows that the dopamine transporter gene (DAT1) influences the re-uptake of dopamine and the anyA9 genotype of this gene i...
Article
Full-text available
Successful action control requires the ability to attend to relevant sensory signals in the environment. This, however, can be complicated when different sensory inputs compete for the brain’s limited resources. Under such conditions, sensory processes interact with top-down attention to selectively process goal-relevant stimuli, while inhibiting i...
Article
Older adults experience difficulties in daily situations that require flexible information selection in the presence of multiple competing sensory inputs, like for instance multi-talker situations. Modulations of rhythmic neural activity in the alpha–beta (8–30 Hz) frequency range in posterior brain areas have been established as a cross-modal neur...
Preprint
Decoding others’ intentions accurately in order to adapt one’s own behavior remains pivotal throughout life. Yet, it is a process that is imbued with uncertainty since others’ intentions are not directly observable and may change over time. In this study, we asked the question of how younger and older adults deal with uncertainty in dynamic social...
Article
Adolescence is a period of life in which social influences-particularly if they come from peers-play a critical role in shaping learning and decision preferences. Recent studies in adults show evidence of a risk contagion effect; that is, individual risk preferences are modulated by observing and learning from others' risk-related decisions. In thi...
Article
Full-text available
Goal-directed behavior requires sufficient resource allocation of cognitive control processes, such as the ability to prioritize relevant over less relevant information in working memory. Findings from neural recordings in animals and human multimodal imaging studies suggest that reward incentive mechanisms could facilitate the encoding and updatin...
Preprint
Full-text available
Older adults experience difficulties in daily situations that require flexible information selection in the presence of multiple competing sensory inputs, like for instance multi-talker situations. Modulations of rhythmic neural activity in the alpha–beta (8–30 Hz) frequency range in posterior brain areas have been established as a cross-modal neur...
Article
Context Antenatal synthetic glucocorticoid (sGC) therapy has been identified as potent programming factor of the hypothalamic-pituitary-adrenal (HPA) axis. We previously observed significantly increased cortisol stress responses in 6-11-yr-old, term-born children exposed to antenatal sGC treatment compared to controls. These findings clearly call f...
Article
The ability to selectively perceive and flexibly attend to relevant sensory signals in the environment is essential for adaptive behavior in everyday life. The fronto-striatal gain control mechanisms likely serve as an important regulatory interface of selective attention and perception. These gain control mechanisms are likely to be modulated by t...
Article
Carrying conversations in public spaces with a plethora of competing sensory inputs demands flexible interactions between attention and perception for selectively processing goal-relevant information. We postulate that the fronto-striatal network plays a key role in regulating this interaction. However, to date the underlying gain control mechanism...
Article
The ability to selectively perceive and flexibly attend to relevant sensory signals in the environment is essential for action control. Whereas neuromodulation of sensory or attentional processing is often investigated, neuromodulation of interactive effects between perception and attention, i.e. high attentional control demand when the relevant se...