
Sholto DavidNewcastle University | NCL · Institute for Cell and Molecular Biosciences
Sholto David
Bachelor of Science
About
6
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Publications
Publications (6)
A recently published meta-analysis on the use of intranasal esketamine for the treatment of major depressive disorder included a mistake in the data analysis. This letter explains the error and offers an alternative analysis. Fortunately in this case the results are little effected.
Background:
Septic shock is the most severe form of sepsis, in which profound underlying abnormalities in circulatory and cellular/metabolic parameters lead to substantially increased mortality. A clear understanding and up-to-date assessment of the burden and epidemiology of septic shock are needed to help guide resource allocation and thus ultim...
Background:
Echinacea preparations are commonly used to prevent and treat upper respiratory tract infection.
Objectives:
To assess current evidence for the safety and efficacy of echinacea containing preparations in preventing and treating upper respiratory tract infection.
Data sources:
MEDLINE, EMBASE, CAB extracts, Web of Science, Cochrane...
Copper (Cu) is essential for most organisms as a cofactor for key enzymes involved in fundamental processes such as respiration and photosynthesis. However, Cu also has toxic effects in cells, which is why eukaryotes and prokaryotes have evolved mechanisms for safe Cu handling. A new family of bacterial proteins use a Cys-rich four-helix bundle to...