Shiro Egawa

Shiro Egawa
National Center of Neurology and Psychiatry · National Institute of Neuroscience

Doctor of Philosophy

About

15
Publications
4,129
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178
Citations
Citations since 2017
12 Research Items
157 Citations
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201720182019202020212022202305101520253035
201720182019202020212022202305101520253035
201720182019202020212022202305101520253035

Publications

Publications (15)
Article
Full-text available
Significant evolutionary shifts in locomotor behaviour often involve comparatively subtle anatomical transitions. For dinosaurian and avian evolution, medial overhang of the proximal femur has been central to discussions. However, there is an apparent conflict with regard to the evolutionary origin of the dinosaurian femoral head, with neontologica...
Article
Full-text available
Living birds (Aves) have bodies substantially modified from the ancestral reptilian condition. The avian pelvis in particular experienced major changes during the transition from early archosaurs to living birds1,2. This stepwise transformation is well documented by an excellent fossil record2–4; however, the ontogenetic alterations that underly it...
Article
Living birds (Aves) have bodies dramatically modified from the ancestral reptilian condition. The avian pelvis in particular experienced dramatic changes during the transition from early archosaurs to living birds. This stepwise transformation is well documented by an excellent fossil record; however, the ontogenetic alterations that underly it are...
Article
Full-text available
Heterodonty is one of the hallmarks of mammals. It has been suggested that, homeobox genes, differentially expressed in the ectomesenchyme of the jaw primordium along the distal-proximal axis, would determine the tooth classes (homeobox code model) based on mouse studies. Because mouse has highly specialized tooth pattern lacking canine and premola...
Article
Full-text available
Background: Flight feathers, a type of feather that is unique to extant/extinct birds and some non-avian dinosaurs, are the most evolutionally advanced type of feather. In general, feather types are formed in the second or later generation of feathers at the first and following molting, and the first molting begins at around two weeks post hatchin...
Article
Full-text available
Understanding morphological evolution in dinosaurs from a mechanistic viewpoint requires the elucidation of the morphogenesis that gave rise to derived dinosaurian traits, such as the perforated acetabulum. In the current study, we used embryos of extant animals with ancestral- and dinosaur-type acetabula, namely, geckos and turtles (with unperfora...
Article
Elucidating how body parts from different primordia are integrated during development is essential for understanding the nature of morphological evolution. In tetrapod evolution, while the position of the hindlimb has diversified along with the vertebral formula, the mechanism responsible for this coordination has not been well understood. However,...
Article
Full-text available
Unlike microevolutionary processes, little is known about the genetic basis of macroevolutionary processes. One of these magnificent examples is the transition from non-avian dinosaurs to birds that has created numerous evolutionary innovations such as self-powered flight and its associated wings with flight feathers. By analysing 48 bird genomes,...
Data
Supplementary Figures, Supplementary Tables, and Supplementary References
Article
Full-text available
Despite the great diversity in digit morphology reflecting the adaptation of tetrapods to their lifestyle, the number of digits in extant tetrapod species is conservatively stabilized at five or less, which is known as the pentadactyl constraint. We found that an anuran amphibian species, Xenopus tropicalis (western clawed frog), has a clawed prot...
Article
Repair from traumatic bone fracture is a complex process that includes mechanisms of bone development and bone homeostasis. Thus, elucidation of the cellular/molecular basis of bone formation in skeletal development would provide valuable information on fracture repair and would lead to successful skeletal regeneration after limb amputation, which...
Chapter
Paired appendages (fins and limbs) are regarded as distinct morphologies by classification of skeletal patterns. On the basis of sequential orientation and articulation of tetrapod limb bones, we can understand that stylopodial/zeugopodial skeletal elements are present in an extinct and extant basal sarcopterygian (coelacanth and lungfish) fin and...

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