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Shinji Kobayashi

Shinji Kobayashi
National Institute Of Public Health Japan · Center for Public Health Informatics

MD, PhD

About

50
Publications
6,887
Reads
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495
Citations
Introduction
Shinji Kobayashi is an associate professor, and currently works at the Department of EHR, Kyoto University. Shinji does research in Hematology and Internal Medicine (General Medicine). Their current project is 'global EHR System: Nation-wide EHR Implementation in JAPAN'. He is also a chair of the open source working group of International Medical Informatics Association.
Additional affiliations
June 2020 - present
National Institute of Public Health
Position
  • Senior Researcher
April 2018 - May 2020
Kyoto University
Position
  • Professor (Associate)
October 2013 - March 2018
Kyoto University
Position
  • Professor (Associate)
Education
April 2001 - March 2005
Kyushu University
Field of study
  • Medical Informatics
April 1988 - March 1995
Kyushu University
Field of study
  • Medicine

Publications

Publications (50)
Chapter
Full-text available
Objective: To assess the impact of open-source projects on making healthcare systems more resilient, accessible and equitable. Methods: In response to the International Medical Informatics Association (IMIA) call for working group contributions for the IMIA Yearbook, the Open Source Working Group (OSWG) conducted a rapid review of current open sour...
Article
Full-text available
Background As a major public health crisis, the novel coronavirus disease 2019 (COVID-19) pandemic demonstrates the urgent need for safe, effective, and evidence-based implementations of digital health. The urgency stems from the frequent tendency to focus attention on seemingly high promising digital health interventions despite being poorly valid...
Article
Full-text available
Objectives: The emerging COVID-19 pandemic has caused one of the world’s worst health disasters compounded by social confusion with misinformation, the so-called “Infodemic”. In this paper, we discuss how open technology approaches - including data sharing, visualization, and tooling - can address the COVID-19 pandemic and infodemic. Methods: In re...
Preprint
UNSTRUCTURED There is a consensus among researchers and practitioners recognizing that the use of artificial intelligence (AI)-based tools can provide high benefits in addition to having significant impacts not only on the practice of medicine but also on medical training and education. At the same time, although the development of AI-based tools i...
Article
Full-text available
Electronic Health Records (EHRs) are at the heart of reforms aimed at improving the efficiency and quality of healthcare services provided to citizens. Although there is still some skepticism, open source (OS) EHR is a growing phenomenon in health informatics. Given the widespread adoption of OS software (OSS) in several domains, including operatin...
Article
Full-text available
Medical Markup Language (MML) is a standard format for exchange of healthcare data among healthcare providers. Following the last major update (version 3), we developed new modules and discussed the requirements for the next major updates. Subsequently, in 2016 we released MML version 4 and used it to obtain clinical data from healthcare providers...
Preprint
Full-text available
The archetype-based approach has now been adopted by the major EHR interoperability standards. Soon, due to an increase in EHR adoption, more health data will be created and frequently accessed. Previous works show that conventional persistence mechanisms such as Relational and XML databases have scalability issues when storing and querying archety...
Article
Medication processes are consisted with multiple steps by professionals and consumers. Physicians prescribe drugs to patient with conformance, but sometimes they were changed to other drugs. We designed concept models to capture medication workflow process records by openEHR archetype models, and four templates were determined with each step of the...
Article
Electronic Health Records (EHRs) are at the heart of reforms aiming for improving the efficiency and quality of citizens healthcare services. Although there is still some skepticism, open source (OS) EHR is a growing phenomenon in health informatics. Given the widespread adoption of OS software (OSS) in several domains, including operating systems,...
Article
Laboratory tests results have potential secondary usage. Each healthcare facility has a laboratory test code. Hence, test code mapping is required to support laboratory technicians. An automatic code mapping can reduce the burden of manual mapping during data preparation. The authors developed a semi-automatic mapping support system that uses the n...
Article
Full-text available
Objectives: Artificial Intelligence (AI) offers significant potential for improving healthcare. This paper discusses how an “open science” approach to AI tool development, data sharing, education, and research can support the clinical adoption of AI systems. Method: In response to the call for participation for the 2019 International Medical Inform...
Article
Full-text available
Background: There are limited data on the prevalence and burden of severe eosinophilic asthma (SEA) both in Japan and globally. This study aimed to assess the prevalence and burden of SEA in Japan. Methods: This study was a retrospective, observational cohort analysis using health records or health insurance claims from patients with severe asth...
Article
Full-text available
Objective: The International Medical Informatics Association (IMIA) Open Source Working Group (OSWG) initiated a group discussion to discuss current privacy and security issues in the open data movement in the healthcare domain from the perspective of the OSWG membership. Methods: Working group members independently reviewed the recent academic and...
Article
Full-text available
openEHR is a widely used EHR specification. Given its technology-independent nature, different approaches for implementing openEHR data repositories exist. Public openEHR datasets are needed to conduct benchmark analyses over different implementations. To address their current unavailability, we propose a method for generating openEHR test datasets...
Article
Full-text available
Mass screening of adults was performed to manage employee healthcare. The screening service defined the data collection format as HL7 Clinical Document Architecture (CDA) R2. To capture mass screening data for nationwide electronic health records (her), we programmed a model within the CDA format and mapped the data items to the ISO13606/openEHR ar...
Article
Many isolated EHRs in Japan hinders the availability of patients' clinical data who need treatment in a region outside the scope of their local EHR. We propose a timelier approach that increases availability of patient clinical data to unknown doctors and has the patient and their representative involved; they can grant access to doctors who are an...
Article
Shared clinical information is an important contribution to regional medicine. Clinical information sharing with patients is also recommended to motivate patients and promote health. On the other hand, the threat of information leaks, caused by internet connected records, is critical to hospitals. The traditional approach is complete isolation of h...
Article
Full-text available
In 2001, we developed an EHR system for regional healthcare information inter-exchange and to provide individual patient data to patients. This system was adopted in three regions in Japan. We also developed a Medical Markup Language (MML) standard for inter- and intra-hospital communications. The system was built on a legacy platform, however, and...
Article
A clinical study requires massive amounts of of lab test data, especially for rare diseases. Before creating a protocol, the hypothesis if the protocol will work with enough amount of patients' dataset has to be proved. However, a single facility, such as a university hospital, often faces a lack of number of patients for specific target diseases....
Article
Achieving interoperability between clinical electronic medical records (EMR) systems and cloud computing systems is challenging because of the lack of a universal reference method as a standard for information exchange with a secure connection. Here we describe an information exchange scheme using HTML5 microdata, where the standard semantic contai...
Article
Full-text available
This article describes the Web application framework for Electronic Health Records (EHRs) we have developed to reduce construction costs for EHR sytems. The openEHR project has developed clinical model driven architecture for future-proof interoperable EHR systems. This project provides the specifications to standardize clinical domain model implem...
Article
Full-text available
The objective is to introduce 'clinical archetype' which is a formal and agreed way of representing clinical information to ensure interoperability across and within Electronic Health Records (EHRs). The paper also aims at presenting the challenges building quality labeled clinical archetypes and the challenges towards achieving semantic interopera...
Article
Medical staff members should match blood products with patients using a barcode authentication system for blood transfusion to prevent medical accidents. However, our hospital only verifies the blood products of the Japanese Red Cross Society and the preserved autologous blood, not the autologous blood salvaged during the operation or from the oxyg...
Article
About 20% of TTP are resistant to plasma exchange. As reported in a few case reports and small case series, rituximab has been used in the treatment of TTP with some benefit. However, the optimal dosing, frequency, and timing of rituximab remain to be determined. We treated three cases of refractory TTP with rituximab. Case 1 exhibited brain sequel...
Conference Paper
The healthcare domain has a specific workflow for medical treatment. The introduction of information security measures that does not considers the behavioral principles of medical workers not only interferes with treatments but may also increase medical risk as a result of human errors due to attempts to bypass these security measures. This is beca...
Article
Full-text available
Because intractable diseases result from unidentifiable causes and are very difficult to treat, they require a lifelong epidemiology database. Japan does not use global unique identifiers, such as social security numbers, so we conducted a feasibility study regarding an electronic health record (EHR). An EHR can be used as a lifelong database and r...
Article
Our hospital acts as a regional core hospital through inter-hospital collaboration. Geographical information is necessary to guide patients to the other hospitals. Although paper maps, which contain directions, nearest public transportation, etc., are usually provided to guide patients to the hospitals, the geographical information tends to change...
Article
Tumor lysis syndrome (TLS) is rare in the treatment of hepatocellular carcinoma (HCC), but here we report a case of acute TLS associated with transcatheter hepatic arterial chemoembolization (TACE) for HCC, in a hepatitis C virus-infected 71-year-old woman with a serum alpha-fetoprotein level at 5,688ng/mL. She underwent TACE therapy with an emulsi...
Article
Objective: Collaboration among medical specialists is necessary for effective care. Although a number of regional medical collaboration systems have been developed using client/server (C/S) models, the drawback of this system is that collaboration between doctors is limited to within this network. To overcome this barrier to collaboration, we have...
Article
Full-text available
A 51-year-old man with non-Hodgkin's lymphoma (NHL) was treated with high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation (PBSCT). Although he had HLA-DRB1 0405 and a positive rheumatoid factor, he was unlikely to develop rheumatoid arthritis (RA) according to diagnostic criteria. However, the patient developed R...
Article
Janus kinases (Jaks) play an important role in signal transduction via cytokine receptors. Tyk2 is a Janus kinase, and we developed tyk2-deficient mice to study the requirement for tyk2 in vivo. Tyk2-deficient mice show no overt developmental abnormalities; however, they display a lack of responsiveness to a small amount of IFNalpha, although a hig...

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Projects

Projects (2)
Project
To provide a method for patients to control access to their EMR based on their access control preferences
Project
This research is supported by "Clinical Study Oriented ICT Infrastructure Development Project - Sustainable Massive Health and Clinical Data Repository for Secondary Use" from Japan Agency for Medical Research and Development, AMED (15lk1010001h0001).