Shima Jazayeri

Tehran University of Medical Sciences | TUMS · Department of Nutrition and Biochemistry

Background Dietary fatty acids can affect brain health by modifying neuronal membrane fluidity. Dietary lipophilic index (LI) and load (LL) may be related to cell membrane fluidity. This study aimed to determine the relationship between dietary LI and LL with symptoms of depression, anxiety and stress. Methods In this cross-sectional study, taken...

Hesperidin, as an antioxidant and anti‐inflammatory agent, has beneficial effects on cardiovascular diseases. This study aimed to determine the effects of hesperidin supplementation on inflammation, oxidative stress, and lipid profile in depressed coronary artery bypass graft surgery (CABG) patients. Eighty patients after coronary artery bypass gra...

Background The association between the Mediterranean-DASH diet Intervention for Neurodegenerative Delay (MIND) diet, odds, and severity of anxiety disorders (AD) is still unclear. We aimed to investigate whether adherence to MIND diet is associated with odds and severity of AD. Methods The present case–control study carried out on 85 patients who...

Abstract Background Depression is more common in diabetic patients, with a 1.5-fold increased risk of death.Melissa officinalis (M. officinalis) have anti-diabetic and anti-depression activities. The study aimed to determine the efficacy of M. officinalis extract on depression, anxiety, and sleep quality in patients with type 2 diabetes with depres...

Objectives: Cornus mas fruit has various antioxidants and anti-inflammatory properties, so this study aims at assessing its effect on menopausal symptoms and sex hormones in postmenopausal women. Methods: In the current randomized, double-blind clinical trial, 84 individuals (42 per group) were participated. C mas hydroalcoholic extract was prep...

Background Dietary pattern has been represented as a contributor to the duration and quality of sleep. This study aimed to review the evidence on this relation among children and adolescents. Study Design This was a systematic review on the association of dietary pattern and sleep. Methods A literature search was conducted for all articles publis...

The drastic decrease in estrogen levels in menopausal women can elevate bone resorption and osteoporosis. Cornus mas extract (C. mas extract) is a potential candidate for treating menopausal‐related bone complications because of its phytoestrogen and anti‐inflammatory contents. It was an interventional double‐blind placebo‐controlled randomized stu...

This study aimed to evaluate the clinical efficacy of probiotic and prebiotic supplementation on the metabolic parameters, liver enzymes, and inflammation in patients with nonalcoholic fatty liver disease (NAFLD). In this study, patients with NAFLD were assigned to receive either probiotic capsule + placebo of prebiotic (probiotic group), oligofruc...

Objective: The aim of this study was to investigate the effects of zinc, vitamin D, and their co-supplementation versus placebo on changes in the Beck Depression Inventory II (BDI-II) score, serum cortisol level, and brain-derived neurotrophic factor (BDNF) in obese/overweight patients with depressive symptoms. Method: This 2 × 2 factorial, doub...

Objectives: Studies have shown that probiotics may decrease anxiety symptoms, but to our knowledge so far no trial has investigated the effects of probiotics in generalized anxiety disorder (GAD). The aim of the present study was to determine the effects of probiotics as adjunctive therapy on anxiety severity and quality of life (QOL) in patients w...

Objective: Diet plays a critical role in the management of non-alcoholic fatty liver disease (NAFLD). Studies on the NAFLD's experimental models have reported that soy had positive effects on the improvement of metabolic parameters. However, there is a lack of clinical trials regarding the efficacy of whole soy foods. Therefore, this study was con...

Background: The assessment of pediatric diet quality is of high interest because food habits that develop in childhood can predict adult diet-related disease. The aim of this study was to examine the association between the Nutrient-Rich Foods (NRF) index score and weight and height status. Methods: This cross-sectional study was conducted in prima...

Background: Although a growing body of evidence suggests an association between obesity and depressive disorder, the association remains inconclusive. Metabolically healthy obese (MHO) phenotype, defined by favorable lipid profile, and normal insulin sensitivity, blood pressure, may be considered as a possible explanation for these inconsistencies....

Objectives: Previous studies have shown that serum levels of vitamin D were lower in attention deficit hyperactivity disorder (ADHD) children compared to healthy controls. The aim of the study was to determine the effect of vitamin D supplementation as adjunctive therapy to methylphenidate on symptoms of children with ADHD. Methods: Sixty-two child...

[fulltext link of article: http://www.tandfonline.com/eprint/t2WfcucSxwm63mjmE8zd/full] Objective: Previous studies have shown that the bioflavonoid quercetin has anti-inflammatory and anti-nociceptive effects. We investigated the effect of quercetin supplementation on inflammation, disease severity, and clinical symptoms in women with rheumatoid...

Background: Acceleration in sputum smear conversion helps faster improvement and decreased probability of the transfer of TB. In this study, we aimed to investigate the effect of green tea extract supplementation on sputum smear conversion and weight changes in smear positive pulmonary TB patients in Iran. Methods: In this double blind clinical...

Effectiveness of school‑based interventions to prevent or control overweight and obesity among school children was reviewed for a 11‑year period (January 2001 to December 2011). All English systematic reviews, meta‑analyses, reviews of reviews, policy briefs and reports targeting children and adolescents which included interventional studies with a...

Non-alcoholic fatty liver, a chronic inflammatory disease, is accompanied by accommodation of extra fat and occurrence of oxidative stress in liver. L-carnitine with anti-inflammatory and anti-oxidant properties may have beneficial effects on NASH. This study was designed to assess the antioxidant and anti-inflammatory effects of L-carnitine on NAS...

Animal studies have shown antioxidant effects of Royal Jelly (RJ) and its effect on insulin resistance as the most common complication of Type 2 diabetes. This study was conducted to determine the effect of RJ intake on serum total antioxidant capacity, Malondialdehyde and insulin resistance in T2DM. In this randomized controlled trial, forty-six t...

Fat deposition and obesity are the primary events in nonalcoholic steatohepatitis (NASH). L-carnitine with function of fatty acid transporting to mitochondria and fat degradation may influence body composition in NASH. This study conducted to investigate the beneficial effect of L-carnitine supplement on body composition in NASH patients following...

Objective: The aim of this study was to determine effects of probiotic yogurt and multispecies probiotic capsule supplementation on mental health and hypothalamic-pituitary-adrenal axis in petrochemical workers. Methods: The present randomized double-blind, placebo-controlled trial was conducted on 70 petrochemical workers. Subjects were randoml...

We are aware of limited data about the effects of purslane on diabetes. Earlier studies have mostly indicated the beneficial effects in animal models. This study aimed to evaluate the effect of purslane seeds on glycemic status and lipid profiles of persons with type 2 diabetes. This cross-over randomized controlled clinical trial was conducted on...

Study design: A randomized, double-blind, placebo-controlled clinical trial. Objective: To assess the effect of alpha-lipoic acid (ALA) supplementation on IL-6, hs-CRP, FBS, anthropometric indices, food intake and blood pressure in male patients with chronic spinal cord injury (SCI). Setting: Imam Khomeini Hospital, Tehran University of Medica...

Low grade inflammation and oxidative stress are the key factors in the pathogenesis and development of diabetes and its complications. Coenzyme Q10 (CoQ10) is known as an antioxidant and has a vital role in generation of cellular energy providing. This study was undertaken to evaluate the effects of CoQ10 supplementation on lipid profiles and glyce...

Considering the increased production of free radicals and inflammatory factors in rheumatoid arthritis (RA) and the effects of bioflavonoid quercetin on reducing oxidative stress, inflammation and blood pressure, the present study examined the effects of bioflavonoid quercetin on total antioxidant capacity (TAC) of plasma, lipid peroxidation and bl...

Objectives: Multiple sclerosis (MS) is an immune-mediated neurodegenerative disease of central nervous system and recent studies show that inflammatory processes are highly associated with neurodegeneration in the brain. The purpose of this study was to investigate the effect of coenzyme Q10 supplementation on inflammatory and anti-inflammatory ma...

Objective: Previous studies have shown a positive effect of zinc as an adjunctive therapy on reducing depressive symptoms. However, to our knowledge, no study has examined the effect of zinc monotherapy on mood. The aim of the present study was to determine the effects of zinc monotherapy on depressive symptoms and serum brain-derived neurotrophic...

This study was conducted to identify the dietary patterns among workers of Oil Terminals Company and to assess their association with socio-demographic and lifestyle factors.The sample size (392) was estimated by considering minimum correlation (r=0.2) between variables. This cross-sectional study was conducted in a representative sample of workers...

N-3 Fatty acids reduce the risk of cardiovascular disease. Previous studies have shown that they may reduce inflammation, oxidative stress, and fat mass in patients with type 2 diabetes, but the results are inconclusive, due, in part, to type of omega-3 fatty acids used. The aim of this study was to determine the effects of pure eicosapentaenoic (E...

Background: Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system in which a higher oxidative stress may contribute to its pathogenesis. The aim of this study was to investigate the effect of coenzyme Q10 (CoQ10) supplementation on oxidative stress and antioxidant enzyme activity in patients with MS. Materials and me...

Increased levels of pro-inflammatory factors, markers of oxidative stress and lipid profiles are known to be associated with several complications. The aim of this study was to determine the association of markers of systemic inflammation, oxidative stress and lipid profiles with insulin resistance in pregnant women in Kashan, Iran. In a cross-sect...

Exercise can lead to acute oxidative stress, which can result in oxidative damage and induce inflammation. Resveratrol may reduce the levels of inflammatory cytokines. Thus, we investigated the effects of this compound on the plasma levels of tumor necrosis factor-α (TNF-α) and interleukin 6 (IL-6) in male professional basketball players. Twenty he...

Background: Variation in cancer incidence in geographical locations is due to different lifestyles and risk factors. Diet and socio-economic position (SEP) have been identified as important for the etiology of cancer but patterns are changing and inconsistent. The aim of this study was to investigate correlations of the incidence of common cancers...

Objective: We aimed to investigate the efficacy of polyunsaturated fatty acids (PUFAs) as an adjuvant treatment in patients with ADHD receiving methylphenidate as well as its side effects. Method: This randomized clinical trial was conducted on 40 ADHD patients aged between 6 and 12 years. Both treatment and placebo groups received methylphenida...

Objective: To compare the therapeutic effects of vitamin D3 plus fluoxetine and fluoxetine alone in patients with major depressive disorder. Methods: In the present double-blind, randomized, placebo-controlled trial, 42 patients with a diagnosis of major depressive disorder based on DSM-IV criteria were randomly assigned into two groups to recei...

Due to the enhanced oxygen requirement of the mitochondria-rich placenta primarily during the third trimester, pregnancy is associated with elevated levels of oxidative stress. This study was designed to determine the effects of daily consumption of probiotic yogurt on oxidative stress among Iranian pregnant women. This randomized single-blind cont...

To determine the plasma total antioxidant capacity (TAC) and its related factors in pregnant Iranian women attending maternity clinics. In a cross-sectional study carried out in Naghavi Maternity Clinic, Shaheed Beheshti Specialty and Subspecialty Polyclinic and 10 antenatal centers, affiliated to Kashan University of Medical Sciences, Kashan, Iran...

Previous studies have shown that inflammatory factors increases in pregnancy and is associated with several complications of pregnancy. The aim of this study was to assess effects of daily consumption of probiotic yoghurt on inflammatory factors in pregnant women. In a randomized clinical trial, seventy primigravid (the first pregnancy) and singlet...

To assess the relationship between vitamin D and serum antioxidant vitamins E and A, and their deficiencies in pregnant women. This cross-sectional study was carried out in the maternity clinic of Naghavi Specialists and Subspecialities Polyclinic, affiliated to Kashan University of Medical Sciences Kashan, Iran between April 2008 and August 2009....

Treatment studies have suggested that omega-3 fatty acids (omega-3 FAs) as monotherapy or adjunctive treatment have therapeutic effects in depression. The authors recently reported a study in which fluoxetine and eicosapentaenoic acid (EPA), which is an omega-3 fatty acid, appeared to be equally effective in controlling depressive symptoms and thei...

Reactive Oxygen Species (ROS) play an important role in the pathogenesis of Rheumatoid Arthritis (RA) exposing these patients to oxidative stress. The aim of the present study was to evaluate the effects of antioxidant supplementations on oxidative status and disease activity in RA patients. Forty nine RA patients (41 females, 8 males, age 48.78±12...

The objective of the present study was to assess the therapeutic effects of the n-3 fatty acid EPA in depression as compared with the antidepressant agent fluoxetine, the common drug for alleviation of this widespread disease. Forty outpatients (twenty-seven females and thirteen males; age, 34.8 (SD 8.7) years; weight, 71 (SD 15.3) kg) with a diagn...

To compare therapeutic effects of eicosapentaenoic acid (EPA), fluoxetine and a combination of them in major depression. Sixty outpatients with a diagnosis of major depressive disorder based on DSM-IV criteria and a score >or=15 in the 17-item Hamilton Depression Rating Scale (HDRS) were randomly allocated to receive daily either 1000 mg EPA or 20...