Shengbo Sang

Shengbo Sang
Taiyuan University of Technology · MicroNano System Research Center

PhD

About

296
Publications
31,160
Reads
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4,527
Citations
Introduction
Skills and Expertise
Additional affiliations
December 2010 - April 2016
Technische Universität Ilmenau/Taiyuan University of Technology
Position
  • Managing Director

Publications

Publications (296)
Article
C-reactive protein (CRP) in human blood have crucial clinical significance as a valid biomarker for acute infection or inflammation. There is an increasing demand for paper-based magnetoelastic biosensors with water repellency and convenience for CRP detection, currently. Herein, we have developed a paper-based Magnetoelastic (ME) biosensor with hy...
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To address the calibration challenge in 3D printing technology, an improved calibration system has been developed, which facilitates the widespread use of bionic stents. Crucially, this system only requires a reference object with known dimensions for automatic calibration. To acquire the required compensation coefficients, various operations are c...
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A pulse‐driven electrochemical synaptic transistor for supersensitive and ultrafast biosensor is proposed. image
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Receptor-functionalized membranes provide a new paradigm for developing mechanical biosensors. However, the lower sensitivity of these biosensors is still a challenge. In this research, a sensitive and thin (1.5 [Formula: see text]m) gold nanoparticles-polydimethylsiloxane (AuNPs-PDMS) membrane is fabricated by reducing HAuCl 4 . Experimental resul...
Article
Recently, mechanical biosensors have attracted more attention on single molecule detection due to its high accuracy, low cost, and convenience. However, the sensitivity of the mechanical biosensors restricted their clinical application. Herein, a mechanical biosensor based on membrane-mediated magneto-stress-electric coupled sensitization (MSEC-MMB...
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There is a growing demand for flexible pressure sensors in environmental monitoring and human–robot interaction robotics. A flexible and susceptible sensor can discriminate multidirectional pressure, thus effectively detecting signals of small environmental changes and providing solutions for personalized medicine. This paper proposes a multidimens...
Article
Electrohydrodynamic (EHD) printing is a micro–nano printing technology based on the principles of electric field and fluid dynamics. It is characterized by high resolution, high precision, and high speed, applied to various materials, including metals, ceramics, and organic materials. Compared with traditional printing technologies, EHD printing of...
Article
The demand for flexible pressure sensors is increasing with the rapid development of wearable smart devices, dexterous manipulators, and human-machine application interfaces. Despite the development of flexible sensors capable of effectively sensing multidimensional forces, the challenge of directly restoring information from objects in contact rem...
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High sensitivity and fast response are the figures of merit for benchmarking commercial sensors. Due to the advantages of intrinsic signal amplification, bionic ability, and mechanical flexibility, electrochemical transistors (ECTs) have recently gained increasing popularity in constructing various sensors. In the current work, we have proposed a p...
Preprint
In the present study, a dual-dielectric planar waveguides (PWGs) coupling sensor was developed to break the waveguide performance limit. Its designs consisted of a sensor planar waveguide (PWG1) for the realization of multimode sensing and a reference planar waveguide (PWG2) for the realization of Fano and EIT-like resonance. The sensitivity and qu...
Preprint
In the present study, a dual-dielectric planar waveguides (PWGs) coupling sensor was developed to break the waveguide performance limit. Its designs consisted of a sensor planar waveguide (PWG1) for the realization of multimode sensing and a reference planar waveguide (PWG2) for the realization of Fano and EIT-like resonance. The sensitivity and qu...
Article
The conventional mechanical biosensor based on stress and electrical conversion can be an effective method to detect key human biomarkers for clinical diagnosis and early disease prevention. However, the applications of this type of biosensor are greatly limited due to their unsatisfactory sensitivity. In this work, a magnetic-sensitized (MS) mecha...
Article
The undulating microstructure rete ridge (RR) located at the junction between the dermis and epidermis plays a crucial role in improving skin mechanical properties and maintaining skin homeostasis. However, the investigation of RR microstructures is usually neglected in current tissue engineering for skin regeneration. Here, to create an epidermal...
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Currently, there is a lack of suitable models for in‐vitro studies of malignant melanoma and traditional single cell culture models no longer reproduce tumor structure and physiological complexity well. The tumor microenvironment is closely related to carcinogenesis and it is particularly important to understand how tumor cells interact and communi...
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In medical and surgical scenarios, the trajectory planning of a collaborative robot arm is a difficult problem. The artificial potential field (APF) algorithm is a classic method for robot trajectory planning, which has the characteristics of good real-time performance and low computing consumption. There are many variants of the APF algorithm, amo...
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The retinal vessels in the human body are the only ones that can be observed directly by non-invasive imaging techniques. Retinal vessel morphology and structure are the important objects of concern for physicians in the early diagnosis and treatment of related diseases. The classification of retinal vessels has important guiding significance in th...
Article
C-Reaction protein (CRP) is a marker of nonspecific immunity for vital signs and wound assessment, and it can be used to diagnose infections in clinical medicine. However, measuring CRP level currently requires hospital-based instruments, high-cost reagents, and a complex process, all of which have limited its full capabilities for self-detection,...
Article
Alpha-fetoprotein (AFP) is a serum biomarker mainly for early-stage diagnosis and prognosis of primary liver cancer in clinical analysis. As a label-free analyte-specific biosensor with ultrahigh sensitivity and broad detection range, photoelectrochemical (PEC) sensor is promising for AFP detection. A unique feature of the PEC sensor, the separatio...
Article
In this study, inspired by the components of cartilage matrix, a photo-cross-linked extracellular matrix (ECM) bioink composed of modified proteins and polysaccharides was presented, including gelatin methacrylate, hyaluronic acid methacrylate, and chondroitin sulfate methacrylate. The systematic experiments were performed, including morphology, sw...
Article
Three-dimensional (3D) printed skin substitutes have great potential for wound healing. However, current 3D printed skin models are limited in simulating heterogeneity and complexity of skin tissue due to the lack of customized bioinks optimized for different skin layers. Herein, different gelatin methacrylate (GelMA)/nano-cellulose (BNC) bioink fo...
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The need for Alpha2-Macroglobulin (α2-M) detection has increased because it plays an important role in the diagnosis of diabetic nephropathy (DN). However, few sensors can realize the high-sensitive detection for α2-M with characteristics of being fast, flexible, wearable and portable. Herein, a biosensor based on a MnFe2O4@chitosan/MWCNTs/PDMS com...
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Plasmon‐enhanced photocatalysis has emerged as a promising technology for solar‐to‐chemical energy conversion. Compared to isolated or disordered metal nanostructures, by controlling the morphology, composition, size, spacing, and dispersion of individual nanocomponents, plasmonic nanostructure arrays with coupling architectures yield strong broadb...
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A factor closely associated with renal disease status in clinical diagnosis is abnormal human serum albumin (HSA) concentration levels in human body fluids urine, serum, etc. The surface stress biosensor was developed as a new type of biosensor to detect protein molecule concentration and has a wide range of clinical applications. However, further...
Article
Osteoarthritis (OA) is one of the most common joint disorders affecting human health. Early detection of OA is essential for effective treatment of the disease. There is a growing demand of techniques for highly sensitive detection of trace OA markers. Herein, the magnetoelastic (ME) biosensor based on Metglas alloy 2826MB is presented to detect ma...
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Osteochondral defect caused by trauma or osteoarthritis exhibits a major challenge in clinical treatment with limited symptomatic effects at present. The regeneration and remodeling of subchondral bone play a positive effect on cartilage regeneration and further promotes the repair of osteochondral defects. Making use of the strengths of each prepa...
Article
Two-dimensional (2D) transition metal carbides (MXene) have attracted great attention for device applications due to their unique structures and excellent properties, such as high electrical conductivity and abundant functional groups on the surface. However, gas sensors based on Ti3C2Tx MXene have the problems of high detection limit and poor long...
Article
A single biomaterial is disadvantageous for constructing skin in vitro, so a mixed biomaterial is more conducive to skin research. In this study, agarose‐chitosan scaffolds with a final concentration of 4% were constructed by freeze‐drying, in which the concentration ratios of agarose to chitosan were 1:3, 2:2, and 3:1. The scaffolds were coated wi...
Article
Graphene nanoflakes (GNFs), with intriguing zigzag edge magnetism, have great potential for the application in high-speed and low-power nanoelectronics and spintronics. However, scattering from edge defects can substantially degrade this novel edge magnetism. Precisely controlled growth of GNFs with zigzag edges on dielectric substrates to suppress...
Article
Gallium nitride (GaN) based NO2 sensor was successfully fabricated via facile hydrothermal and further nitridation method. The morphology and structure indicate that GaN nanoshuttles have large specific surface areas and plentiful oxygen adsorption sites. The most superior response of around 14.56 towards 100 ppm NO2 at the operating temperature of...
Article
Rete ridges (RRs) are distinct undulating microstructures at the junction of the dermis and epidermis in the skin of humans and certain animals. This structure is essential for enhancing the mechanical characteristics of skin and preserving homeostasis. With the development of tissue engineering and regenerative medicine, artificial skin grafts hav...
Preprint
Full-text available
When robot hands work in a com plex environment, it not only needs to sense the objects in contact, but also needs to respond to remote events before physical contact. In this way, robot hands can make prediction, so as to better adapt to the complex environment. In this paper, we have designed a flexible sensor array, which integrates piezoresisti...
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Flexible pressure sensors usually exhibit high sensitivity, excellent resolution, and can be mass-produced. Herein, a high-resolution, capacitive, paper-based, 3D-printed pressure sensor with a simple, low-cost preparation method is proposed. The sensor has a wide detection range (300–44,000 Pa), a short response time (<50 ms), and high mechanical...
Article
A new design of flexible magnetoelastic (ME) biosensor based on TbDyFe/polystyrene-poly (ethylene-butylene)-polystyrene block copolymer (SEBS) film for the osteoarthritis (OA) marker matrix metalloproteinase 3 (MMP-3) detection is presented. This article studied a novel flexible ME film to replace the traditional rigid substrate for biosensors. The...
Article
Piezoelectric flexible sensors have been used to detect biomolecules such as sweat and glucose because of their passive, simple structure and high sensitivity. This paper proposes a novel flexible piezoelectric Au-BaTiO3-FeGa & PDMS biosensor in which magnetostrictive deformation amplifies the surface stress generated by biomolecules combining on t...
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Individual chemotherapeutic drugs usually suffered drug resistance in the cancer treatment, and the combination therapy has aroused great interest which can reduce the resistance. Glutamine inhibitor (V9302) and chemotherapy drug doxorubicin (DOX) were combined for the first time to construct a pH‐sensitive multi‐mode synergistic treatment system B...
Article
ZnO/NiO heterojunction nanofibers were synthesized by an electrostatic spinning technique in this work. The morphologies, crystal structures, and compositional features of the ZnO/NiO nanofibers were analyzed by SEM, TEM, XRD, and EDS characterization. ZnO/NiO nanofibers with Zn contents of 37.5 at% showed a 46% response to 300-ppm ammonia gas at r...
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In current industrial production, robots have increasingly been taking the place of manual workers. With the improvements in production efficiency, accidents that involve operators occur frequently. In this study, a flexible sensor system was designed to promote the security performance of a collaborative robot. The flexible sensors, which was made...
Article
Although fantastic milestones of Gallium nitride (GaN)-based materials in optoelectronic devices had been reached, the focus on the optimization of their geometrical structure for gas-sensing applications was relatively scarce. In this work, we demonstrated NO2 gas sensor based on p-type GaN hexagonal pits (GaN-HP) with high surface-to-volume ratio...
Article
Accurate detection of NO2 gas with low concentration and high stability is of great significance to ecological protection and human health. In this work, hollow porous GaN nanofibers were fabricated by a low-cost solvothermal method and controlled nitridation process. Systematic characterizations results demonstrate large specific surface and abund...
Article
Black Phosphorus (BP) has attracted considerable attention in gas detection fields attributing to layer-dependent direct bandgap, and high carrier mobility. Currently, many researchers use blended polyethyleneimine/polyethylene-glycol (PEI/PEG) functionalized two-dimensional (2D) material to detect carbon dioxide (CO2). However, the detection rage...
Article
People with neurological deficits face difficulties perceiving their surroundings, resulting in an urgent need for wearable electronic skin (e-skin) that can monitor external stimuli and temperature changes. However, the monolithic structure of e-skin is not conducive to breathability and hinders hair growth, limiting its wearing comfort. In this w...
Preprint
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Objective To verify whether MicroRNA-1 (miR-1) small nucleic acid drugs can delay the progression of osteoarthritis (OA) by downregulating Indian hedgehog (Ihh). Methods Costal chondrocytes were isolated from male Sprague-Dawley rats aged 2–3 days. Second-generation chondrocytes were transfected with miR-1 mimic and empty vector with lipo3000 for...
Article
Ti3C2 MXene has received tremendous interest as a potential electrode in flexible electronics due to its promising electronic and mechanical properties. However, its inherent properties determine the interfacial performance and the interfacial properties with MoS2 are critical to nanoelectronics device. Based on first-principles calculations, the m...
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Superparamagnetic nanoparticles have been widely used as contrast agents in magnetic resonance imaging (MRI). The combined use of multiple imaging modes can provide more accurate information for clinical diagnosis. In this paper, a MRI/fluorescence dual-mode imaging contrast agent was developed by a simple method. The method is to make the fluoresc...
Article
Up to now, there were a large number of literatures on the detection of gaseous formaldehyde (HCHO), however the liquid HCHO, which had the same harmfulness as gaseous HCHO, was rarely paid attention to by people. In this work, the electrospinning nanomaterial preparation process was used to fabricate the liquid HCHO electrochemical sensor. Firstly...
Article
Black phosphorus (BP) has recently attracted significant interest in gas sensing because of its outstanding electronic and optical properties. In this paper, we demonstrated a series of gas sensors for detecting NH3 at room temperature that were based on BP nanosheets that were exfoliated for various durations. The BP nanosheet gas sensors showed e...
Article
Magnetoelastic (ME) biosensors based on the magnetoelastic effect can detect specific substances through surface functionalization and bioanalysis as described in the article number 2101216 by Zhongyun Yuan and co‐workers. Then change of the load on the ME biosensors can cause its resonance frequency to shift. Finally, the shift in resonance freque...
Article
In the present work, the dicyandiamide N-doped supra-CNDs were synthesized just within 24 hours. The supra-CNDs exhibited a new strong absorption band at longer wavelengths (450-900 nm) and higher photothermal conversion efficiency (55.49% and 46.02% irradiation at 730 nm and 808 nm, respectively). The supra-CNDs can still maintain excellent photot...
Article
The repair of nasal cartilage lesions and defects is still a difficult problem in nasal surgery, and nasal cartilage tissue engineering will be an effective way to solve this problem. Hydrogel has excellent application potential in tissue engineering. In order to produce a 3D printable scaffold for cartilage regeneration, we prepared gelatin methac...
Article
The vast majority of patients with corneal blindness cannot recover their vision due to the serious shortage of donor cornea. However, the technology to construct a feasible corneal substitute is a promising treatment method for corneal blindness. In this paper, methacrylated gelatin (GelMA)-methacrylated hyaluronic acid (HAMA) double network (GHDN...
Article
Background Tremendous progress has been made in the field of cartilage repair and regeneration, particularly with tissue-engineering approaches. This study aims to estimate the global status and current trends in the field of cartilage tissue engineering.Methods Publications from 2011 to 2020 on tissue engineering for cartilage repair and regenerat...
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The establishment of vascularization is the basic prerequisite for the survival and functionalization of three-dimensional (3 D) tissue-engineered constructs. The application of hydrogel to tissue regeneration has promoted the research and development of regenerative medicine. In this study, we fabricated the composite scaffold composed of gelatin...
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Back Cover: In article number 2100643 by Shengbo Sang and co‐workers, a paper‐based sensing array with layered structure and high sensitivity is prepared by using a writing method which is applied to graphic pressure sensing and distance position detection. Because many scenarios require a safe distance to be maintained, particularly under the infl...
Article
Dealloying technique is an important approach to design porous structures and highly active catalysts. In this work, monolithic nanoporous (Mn,Ni)-doped Cu2S skeletons with controllable composition and tunable porosity are synthesized via dealloying and sulfuration technique. The as-prepared S-np-Mn70Cu29Ni1 electrode exhibits outstanding catalytic...
Article
Nucleolus selective imaging can reveal the nucleolus structure and characters of cells in different states, and is considered critical in early disease diagnosis and treatment, and in designing targeted delivery systems. In this paper, we analyzed the factors affecting the nucleolus targeting properties of carbon dots by preparing a variety of carb...
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The development of wearable devices has shown tremendous dynamism, which places greater demands on the accuracy and consistency of sensors. This work reports a flexible sensing system for human health monitoring of parameters such as human pulse waveform, blood pressure and heart rate. The signal acquisition part is a vertically structured piezores...
Article
Carbon nanotube (CNT) composite materials are very attractive for use in neural tissue engineering and biosensor coatings. CNT scaffolds are excellent mimics of extracellular matrix due to their hydrophilicity, viscosity, and biocompatibility. CNTs can also impart conductivity to other insulating materials, improve mechanical stability, guide neuro...