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Dr. Shazia Kanwal Malik. PhD. (Molecular Genetics and Plant Biotechnology) MSc Botany (Gold Medalist) Academic Role of Honour MPhil Botany, Role of Honour I am a Student of The Spiritual Scientist Hazrat Khwaja Shamsuddin Azeemi. I am also the President of Volunteers of Humanity and Pakistan Agritech Society. Facebook Links https://www.facebook.com/pakistanagritechsociety https://www.facebook.com/volunteersofpakistan https://www.facebook.com/volunteersofhumanity
September 2016 - August 2018
- The Research project entitled "Anticarcinogenic activity of Terpenoid containing plants against induced Hepatocellular carcinoma (HCC). The research work critically examined the potential role of naturally occurring terpenoids from diverse botanical origins for chemoprevention as well as chemotherapy of liver tumors by both in vivo and in vitro experiments. We successfully identified the anticancer "Terpenes" giving better and non-toxic results against HCC in comparison to the synthetic drugs.
November 2009 - October 2010
Government College University, Lahore
- Research Officer
- The Research Project was to investigate the pharmacological (Antibacterial, antifungal, antioxidant, anthelmintic) properties of some medicinal tree of Pakistan i.e. Pterospermum acerifolium, Diospyros malabarica, Putranjiva roxburghii, and Cycas revoluta. their phytochemical and medicinal analysis revealed that all of them have significant antibiotic property against G+ and G- bacteria and fungi. Their extracts were equally active against oxidative stress and gastrointestinal worms of sheep.
January 2008 - December 2010
- This project was about establishment of biodiversity park at Kasur. This project was a joint venture between EPA department and GCU Lahore under the supervision of Dr Zaheer u Din Khan.
The current study encompassed the extraction of phytochemicals from the fruit of a well-known traditional medicinal tree, viz. Diospyros malabarica with different solvents and evaluation of their in-vitro antimicrobial and antioxidant activities using standard methods and standard drugs. The preliminary phytochemical investigation demonstrated the...
Background: Medicinal plants are used in anticancer therapies from ages. The very first time we have not only screened anticancer medicinal plants from Pakistan but also identified anticancer plant terpenes. This study will definitely pave the way towards anticancer drug development after animal trials. Materials and Methods | This study was based...
Purpose: To identify a novel source of terpenoid anticancer compounds from P. juliflora (Sw.) DC. (Leguminosae) pods as a medicinal substitute for cancer medicines. Methods: The pods were collected, dried and pulverized. The ethanol extract was prepared by maceration. Various phyto-constituents were detected in the extract by UV-VIS spectroscopy at...
In the current research, in vitro antiradical potential of some medicinal trees of Lahore, Pakistan was investigated. Various fruits and pods of 25 medicinal plants (Prosopis juliflora, Carissa carandas, Ceiba speciosa, Heterophragma adenophyllum Cestrum diurnum Jacaranda mimosifolia, Diospyros malabarica, Terminalia bellerica, Ficus lyrata, Diospy...
Terpenoid contents of traditionally used ethnobotanically important plants (n=25) were determined. Ethanol extracts of seeds, fruits, pods, branches, bark, rhizome and whole plant parts were prepared and preliminary phytochemical investigation was carried out. Total terpenoid contents in ethanol extracts were determined through qualitative and quan...
The present study is based on the antioxidant potential of an important t sago palm, Cycas revoluta Thunb. The crude extracts of seed pulp and leaf were extracted by maceration process in polar & non polar solvents, viz: petroleum ether, chloroform, methanol and water. Antioxidant profile of Cycas revoluta Thunb was evaluated by three methods: scav...
The aim of the present study was to evaluate the antimicrobial potential including MIC of traditionally used and ethnobotanically important tree Pterospermum acerifolium fruit. Laboratory isolates of six pathogenic microorganisms, viz., Staphylococcus saprophyticus, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Aspergillus parasi...
The current research is the investigation of an ethnopharmacological impact i.e., anthelmintic action of fruits of three traditionally used trees, i.e. Pterospermum acerifolium Linn. Diospyros malabarica Kostel and Putranjiva roxburghii Wall. The crude extracts of fruits were obtained in polar and non-polar solvents i.e., petroleum ether, chlorofor...
In the present study investigation was done to look at skin ailments created by utilized beauty care products and cosmetics testers. Twenty makeup specimens (Lipsticks) were collected from a super market. Each specimen underwent clinical examinations and laboratory tests such as direct KOH (20 %) analysis and culturing on Potato Dextrose Agar plate...
Sulfur is the element with the largest number of allotropes (30), but only a few are found in nature and occur in biological systems. Elemental sulfur as fungicidal is well documented in certain specialized prokaryotes but has rarely been detected in eukaryotes. In the current work isolation, purification and identification of crystalline sulfur (α...
The present study was based on the investigation of an ethnopharmacological activity, i.e. antioxidant potential of a traditionally used important tree, Pterospermum acerifolium Linn. The crude extracts of fruit, leaf, stem and bark were extracted in polar & non polar solvents, viz: petroleum ether, chloroform, methanol and water by maceration. Ant...
Present study describes the pretreatment of sugarcane bagasse with different physical and chemical agents for the production of cellulolyic enzymes by Trichoderma viride using submerged fermentation. Bagasse was pretreated with steam (121°C and 200°C) and different chemicals like NaOH, H2SO4, H2O2 and NaHClO3 to get the maximum yield of cellulases....
Present studies describe the optimization of process parameters for the production of cellulases by Trichoderma viride using submerged fermentation technique. The fermentation experiments were carried out in shake flasks using pretreated bagasse. Maximum production of cellulases (CMCase 1.57 U/ml/min, FPase 0.921 U/ml/min) was observed after a ferm...
I am interested to get natural red colour to add in food. Can anyone guide me about it easy and cheap natural source.
My PhD thesis entitled as "Anticarcinogenic activity of Terpenoid containing plants against induced Hepatocellular Carcinoma (HCC). My extensive experimental work critically examined the potential role of naturally occurring -terpenoids from 25 plants extracts for chemoprevention as well as chemoprotective against liver tumors by both in vivo and in vitro experiments. I successfully identified the anticancer "Terpenes" giving better and non-toxic results against HCC in comparison to the synthetic drugs.
Now I want to excel my experimental work with the use of colour therapy. If anyone of you is interested then contact me.
If a plant extract (1mg/mL) showed 28 % cytotoxic inhibition against normal cell line, then what would be its IC50.
Secondly, how can we calculate one exact dose of the same plant extract in in vivo testing, on the base on invitro test. plz guide and help me in calculations.
During GCMS analysis, the results shows different mass peaks of different compounds. What does this mass peak means, are the indicating peak number of the eluting compound.