Sharada L Deore

Sharada L Deore
Govt. College of Pharmacy, Amaravati-444604 MS India · Pharmacognosy and Phytochemistry

M.Pharm, Ph.D

About

52
Publications
21,530
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1,236
Citations
Citations since 2017
2 Research Items
870 Citations
2017201820192020202120222023050100150200
2017201820192020202120222023050100150200
2017201820192020202120222023050100150200
2017201820192020202120222023050100150200
Additional affiliations
December 2016 - March 2017
Govt. College of Pharmacy, Amaravati-444604 MS India
Position
  • Professor
July 2008 - December 2008
Sant Gadge Baba Amravati University
Position
  • Researcher
October 2006 - June 2016
Govt. College of Pharmacy, Amaravati
Position
  • Professor (Assistant)

Publications

Publications (52)
Article
Silver nanoparticles owing to its wide range of biomedical application has recently gained remarkable interest in cancer nanomedicine. The present research work was stemmed to investigate the anticancer activity of phytosynthesized silver nanoparticles against human cancer cell lines. Phytosynthesis of silver nanoparticles (SNP) was achieved by usi...
Book
Key features: Easy to carry handbook Unique outline of topics Focus on only necessary information Quick-reference tabular formats Useful for GPAT/NIPER/NET/SET examinations Index 1. Sources of Crude drug, Plant families, Biogenesis of Phytochemicals 2. Crude Drug Classification 3. Microscopy of crude drugs: Stomata, Trichomes, Crystals, Vessels...
Article
Thus present research work deals with the development and evaluation of topical photo protective formulation, containing antioxidant, wound healing, anti-inflammatory and rather photo protective poly phenols like curcumin, quercetin, resveratrol and safranal. The present research work provides stable natural photo protective formulation with antiox...
Article
Traditional oral dosage forms prone to first pass metabolism and degradation due to enzymes but mucoadhesive films able to bypass first pass metabolism and related degradation. It also offers more patient compliance without risk of chocking in case of paediatric and geriatric patients. Present review has summarised basics of mucoadhesion, compositi...
Article
Lipid dosage forms are attractive delivery systems for hydrophobic drug molecules. Emulsion is one of the popular system since many decades. Pharmaceutical applications of emulsions widened especially after micro and nano-emulsion emergence. This paper is an attempt to summarise comparative aspects like definition, theories, types, methods of prepa...
Article
Nebivolol is a third-generation beta-a drenoceptor antagonist. It differs from other beta-a drenoceptor an tagonists as it combines highly selective beta (1)-adrenoceptor antagonist properties with nitric oxide-mediated vasodilator actions and beneficial effects on endothelial function. But this very useful drug use is limited due to challenge of p...
Article
Candesartan is potent antihypertensive drug of class angiotensin II receptor antagonist. But it exhibits poor water solubility and extensive first pass metabolism. Present research deals with development of candesartan buccal film. Optimisation of buccal film was done by design expert. Optimised concentration range selected for development of trial...
Article
Sunlight despite of source of life and energy creating major health challenges like sunburn, pigmentation, wrinkles, dermatitis, urticaria, ageing, immune-suppression and number of skin cancers too. Sun protective clothes and or sunglasses provide insufficient and less convenient approach to get rid of all these health hazards. So sunscreen protect...
Article
Roots of Chlorophytum tuberosum are very popular and well known for its aphrodisiac, immune-modulatory andtonic properties. In this study the antioxidant effect ethanolic and aqueous extract of dried roots of Chlorophytumtuberosum Baker was evaluated by 2,2-diphenyl-1,1-picrylhydrazyl (DPPH) radical scavenging, Nitric oxideradical scavenging assay...
Article
Objective: To establish comparative pharmacognostic, phytochemical and biological evaluation parameters between five Chlorophytum species i.e. Chlorophytum borivilianum Santapau and Fernades, Chlorophytum comosum (Thunb.) Jacq., Chlorophytum tuberosum Br., Chlorophytum laxum R. Br. and Chlorophytum arundinaceum Baker, of very popular Ayurvedic plan...
Article
Full-text available
Objectives: We aimed to develop, compare and optimise rapid and high yield extraction method for saponins of Safed musli using conventional extraction techniques and as well as modern microwave assisted solvent extraction method. Materials and methods: Roots of Safed musli (Chlorophytum borivilianum) are extracted by maceration, soxhlet, sonication...
Book
CONTENTS Chapter 1: Extraction and Isolation Methods  Extraction of plant drugs  Choice of extraction method  Drying of crude drugs  Methods of extraction  Maceration  Percolation  Infusion  Decoction  Water distillation  Steam Distillation  Expression  Enfleurage  Ultrasound Extraction  Microwave assisted extraction  Craig apparatu...
Article
Full-text available
Context: Bombax ceiba Linn. (Bombacaceae) is a well-known plant for its antihypertensive, antioxidant, antidiabetic, aphrodisiac and uterine tonicity properties. Aims: To study pharmacognostical, physicochemical and phytochemically the roots of this plant. Methods: Pharmacognostical study included the macroscopic characters like size, color, surf...
Article
Full-text available
A new simple, rapid, selective and precise high performance thin layer chromatographic (HPTLC) method has been developed for simultaneous estimation of vasicine, glycyrrhizin, eugenol, and cineole in herbal cough syrup. The retention factors of vasicine, glycyrrhizin, eugenol, and cineole are 0.53, 0.44, 0.75, and 0.77, respectively. Chromatography...
Data
Full-text available
Archives Most popular articles Most cited articles Show all abstracts Show selected abstracts Export selected to Viewed PDF Cited ORIGINAL ARTICLES Protective effect of stem bark of Ceiba pentandra linn. against paracetamol-induced hepatotoxicity in rats.60584 PMID:21808535 [ABSTRACT] [FULL TEXT] [PDF] [CITATIONS] [PubMed] 11,208 256 16 Brine shrim...
Book
PART-I PHARMACOGNOSY CHAPTER 1: PHARMACOGNOSY: SCOPE AND HISTORY  Introduction  Scope  History o Alternative systems • Ayurveda • Siddha • Unani • Homeopathy • Chinese • Kampo • Aromatherapy • Naturopathy • Yoga  Crude drug: Classification  Alphabetical classification  Morphological classification  Taxonomic classification  Biological...
Article
The present study was designed to study the sunscreen activity of herbal cream formulation containing flavonoids extracted from Tagetes erecta Linn flowers (Family-Asteraceae), Cucumis sativus fruits (Family-Cucurbitaceae) and essential oil extracted from leaves of Ocimum sanctum (Family-Labiatae). The parameters of creams complies with official ac...
Article
In continuation to our work for the development of new anticancer agents, novel clubbed triazolylindenoisoquinoline derivatives were synthesized in good yields and characterized by IR, 1H NMR, mass spectral and elemental analyses. The prepared compounds were tested for their in vitro anticancer activity against 05 human cancer cell lines including...
Article
In the present study, a series of twenty new N-(1,5-diphenyl-4,5-dihydro- 1H-3-pyrazolyl)-N-(4-phenyl-1,3-thiazol-2-yl)amine (4a-j) and N-(5-phenyl-4,5-dihydro-1H-3-pyrazolyl)-N-(4-phenyl-1,3-thiazol-2-yl)amine (5a-j) have been synthesized in 70-85% yield by a microwave-assisted solvent-free condensation of N1-(4-phenyl-1,3-thiazol-2-yl)-(Z)-3-phen...
Article
Background Reserpine is an indole alkaloid and found to be very unstable in various conditions previously. Here a simple, selective, precise and stability indicating high-performance thin-layer chromatographic method of analysis of reserpine was developed and validated. Materials and methods The method employed TLC plates precoated with silica gel...
Article
Ayurvedic preparations contain toxic elements like heavy metals and other chemicals exceeding their permissible limits. Ayurvedic method of detoxification of such products involves Shodhana. Hence, in present paper it has been decided to replace Ayurvedic Shodhana process by chemical purification method and to study the benefits and/or drawbacks of...
Article
Full-text available
A new series of N-{4-methyl-5-[4-(4-oxo-2-phenyl(1,3-thiazolidin-3-yl)]-5-sulfanyl(1,2,4-triazol-3-yl)-1,3-thiazol-2-yl }acetamide (7a-l) was synthesized in order to determine their antimicrobial activity and feasible structure–activity relationships. The compounds were synthesized in good yield and the structures of all newly synthesized compounds...
Article
Full-text available
Many ayurvedic natural products have properties to rejuvenate and protect the skin from environmental pollution, chemicals, atmospheric temperature fluctuation, UVA and UVB radiation, wrinkling, hyperpigmentation (excessive tanning) and inflammation. The present review focuses on properties and mechanism of action of photoprotective antioxidant phy...
Article
The reaction of ethyl 2-amino-4-methylthiazole-5-carboxylate 1 with acetic anhydride followed by reaction with hydrazine hydrate yields the ethyl 2-acetamido-4-methylthiazole-5- carboxylate 2 and N-[5-(hydrazinecarbonyl)-4- methylthiazol-2- yl]acetamide 3, respectively. The compound 3 on further reaction with alcoholic potassium hydroxide-carbon di...
Article
The purpose of this study was to investigate the anticancer activity of saponin fractions of Chlorophytum borivilianum belonging to family liliaceae. The MTT (methylthiazolyldiphenyl-tetrazolium bromide) and SRB method was used to evaluate the antiproliferative activity of the mehanolic extract and crude saponin extract. DNA fragmentation assay was...
Article
The present communication deals with the identification and characterization of bioactive principles from the roots of Chlorophytum borivilianum. Methanolic extract and its fractions were used to isolate different phytoconstituents. The structures of isolated compounds were characterized and elucidated with chemical and spectroscopic techniques suc...
Article
A rapid and sensitive high-performance thin-layer chromatographic (HPLC) method was developed and validated for the quantitative estimation of boswellic acids in formulation containing Boswellia serrata extract (BSE). Simple extraction method was used for isolation of boswellic acid from formulation sample. The isolated samples were chromatographed...
Article
Many herbal remedies have been employed in various medical systems for the treatment and management of different diseases. The plant Argyreia speciosa Linn.f. (Syn: Argyreia nervosa) belongs to family convolvulaceae has been used in different system of traditional medication for the treatment of diseases and ailments of human beings. It is reported...
Article
Many herbal remedies have been employed in various medical systems for the treatment and management of different diseases. The plant, Argyreia speciosa Linn. f. (Syn: Argyreia nervosa) belongs to family convolvulaceae has been used in different system of traditional medication for the treatment of diseases and ailments of human beings. It is report...
Article
The present communication deals with the laboratory studies carried out to ascertain the anthelmintic properties of Chlorophytum borivilianum Sant. & Fernandez saponin extracts against Pheretima posthuma and Ascardia galli. Methanolic extract (ME), crude saponin extract (CSE) and purified saponin fractions (PSF) were used as test solutions. Piperaz...
Article
Alcohol and aqueous extracts from the leaves of Cleodendrum infortunatum were investigated for their anthelmintic activity against Pheretima posthuma and five concentrations (5, 10, 15, 20 and 25 mg/ml) of each extracts were studied in activity, which involved the determination of time of paralysis and time of death of the worm. Both the extracts e...
Article
Full-text available
Antioxidant activity of aqueous, chloroform and methanol extract of the aerial parts of plant of Tricholepis glaberrima DC were evaluated for the antioxidant activity by the FTC and TBA methods. Methanolic extract showed higher antioxidant activity than the chloroform and aqueous extract. The results obtained in the present study indicate that the...
Article
Full-text available
The present communication deals with the laboratory studies carried out to ascertain the larvicidal properties of Chlorophytum borivilianum Sant. and Fernand. saponin extracts for the mosquito species Anopheles stephensi, Culex quinquefasciatus and Aedes aegypti. Methanolic extract (ME), crude saponin extract (CSE) and purified saponin fractions (P...
Article
Full-text available
The plant, Lagenaria siceraria (Family: Cucurbitaceae), known as bottle gourd, Calabash, Doodhi, and Lauki, is a common fruit vegetable used throughout the India. The antioxidant activities of different concentrations of ethanol extracts of fruits of Lagenaria siceraria the were determined by the four assay techniques i.e. DPPH radical scavenging a...
Article
The present investigation deals with the neuropharmacological investigations of different doses (100,300 mg/kg.) of methanol, chloroform, aqueous extract of aerial parts of Tricholepis glaberrima. The acute administration of extract reported increase in discrimination index in object recognition test, muscle relaxation, increase in reaction time in...
Article
Chlorophytum borivilianum belonging to family liliaceae is a very famous for its adaptogenic, immunomodulatory properties in traditional Indian system of ayurveda. In recent era there is a great thrust on screening of herbal extracts and formulations for Adaptogenic action as stress is a daily phenomenon faced by every human. The aim of the present...
Article
Ethanol and aqueous extracts from the fruits of L. siceraria were investigated for their anthelmintic activity against Pheretima posthuma and Ascardia galli. Various concentrations (25, 50, 100mg/mL) of aqueous and ethanolic extracts were tested in the bioassay, which involved determination of time of paralysis and time of death of the worms. Both...
Article
Full-text available
Alcohol and aqueous extracts from the seeds of Cassia tora were investigated for their anthelmintic activity against Pheretima posthuma and Ascardia galli. Three concentrations (25, 50 and 100 mg/ml) of each extracts were studied in activity, which involved the determination of time of paralysis and time of death of the worm. Both the extracts exhi...
Article
Full-text available
The antioxidant activities of different concentrations of ethanol extracts of the leaves of Croton caudatum were determinedby the four assay techniques i.e. DPPH radical scavenging assay, Reducing power ability, Hydrogen peroxidescavenging assay and thiocyanate method. Ethanol extract of leaves of Croton caudatum has shown effective antioxidantacti...
Article
Pterospermum acerifolium is used traditionally in the management of tumors. Ethanol and Water extracts showed good antimitotic activity against meristamatic cell growth. Both extracts also showed good inhibition on yeast cell growth with IC 50 47.88 mg/ml and 39.15 mg/ml respectively. The mode of action of both extract with antiproliferative activi...
Article
The aqueous, hydro alcoholic and methanolic extract of Chlorophytum borivilianum (liliaceae) roots were investigated for antiinflammatory and antioxidant activity. Antiinflammatory activity was studied by carragenan induced rat paw oedema model. Methanolic and aqueous extract shows most significant antiinflammatory activity as compared to hydro alc...
Article
Full-text available
Chlorophytum borivilianum, a medicinal plant belonging to family liliaceae, has been traditionally used as adaptogenic drug. Various aspects of its phytochemistry and pharmacology are going to be studied world over by researchers. Present study is done on mucilage, major constituent, obtained from tubers of C. borivilianum. Various physicochemical...
Article
Enicostemma axillare (Lam.) Raynal. syn. E. littorale Blume (Family— Gentianaceae) is a perennial herb found throughout the greater part of India. Locally it is known as chota chirayita and used in indigenous medicines in the treatment of fevers and as bitter tonic and forms one of ingredients of many hypoglycemic marketed formulations. In the pres...
Article
Plants and plants extracts have been used for many years as folklore medicine. Therefore the objective of present study was to screen different extracts of Butea monosperma for antidiabetic activity and to rationalize the folk claim. In light of the traditional claim of Butea monosperma in the treatment of diabetes, investigations were carried out...
Article
The Chlorophytum borivilianum belonging to family liliaceae is traditionally used medicinal plant having the folk claims like immunomodulator, anti-diabetic, anti-arthritic, used in prenatal and postnatal symptoms, in diarrhea etc. Present study has tried to evaluate in vitro antimicrobial activity (Well diffusion method) of aqueous, hydro alcoholi...
Article
Systemic lupus erythematosus (SLE) is a chronic, life-threatening autoimmune disease in which the immune system is unbalanced, causing inflammation and tissue damage to virtually any organ in the body. There is no safe and reliable therapy for most serious autoimmune diseases, such as systemic lupus erythomatosus. Severe cases require treatment wit...

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