Shantala Hegde

Shantala Hegde
National Institute of Mental Health & Neuro Science · Department of Clinical Psychology

MSc, MPhil(Cli Psych), PhD (Cli Neuropsychology)

About

65
Publications
11,334
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462
Citations
Additional affiliations
June 2012 - present
National Institute of Mental Health and Neuro Sciences
Position
  • Professor (Assistant)
June 2012 - January 2017
National Institute of Mental Health and Neuro Sciences
Position
  • Assistant Professor (Neuropsychology)

Publications

Publications (65)
Article
Full-text available
Background Cognitive deficits are one of the core features of major depressive disorder (MDD) that play crucial role in functional recovery. Studies have explored cognitive deficits in MDD, however, given inconsistent results, especially in mild-moderate MDD. Recently, studies have explored music as cognitive ability in various clinical conditions....
Article
Non-motor symptoms (NMS) are common among Parkinson's disease (PD) patients and have a significant impact on quality of life. NMS such as deficits in emotion perception are gaining due focus in the recent times. As emotion perception and cognitive functions share certain common neural substrates, it becomes pertinent to evaluate existing emotion pe...
Poster
Full-text available
This is a single case study aiming to evaluate effectiveness of cognitive retraining (CR) in young stroke. Baseline neuropsychological evaluation was carried out with patient and based on Neuropsychological profle, drill based , hierarchial cognitive retraining tasks and music based tasks were designed targeting specific cognitive functions. In add...
Preprint
Full-text available
This paper is a written account of the ICMPC-ESCOM 2021 workshop “Cross-Cultural and Decolonized Research,” and an opportunity to dig deeper into some of the topics that were discussed over the course of organizing and presenting the workshop. The paper is divided into four sections: 1) why we organized the workshop, and our reflections on it; 2) a...
Article
Cognitive impairment of different severity with eventual progression to dementia in Parkinson’s disease (PD) appears during the course of the disease. In this study, transcranial magnetic stimulation (TMS) was used to assess cortical excitability changes in PD patients with varying cognitive impairment. We aimed to identify the TMS parameters that...
Article
INTRODUCTION: Psychosis is one of the incapacitating non-motor symptoms of Parkinson’s disease (PD). Although several risk factors that include older age, rapid eye movement sleep (REM) behavior disorder (RBD), depression, and cognitive dysfunction have been identified, the exact neural correlates remain elusive. As cognitive impairment has a close...
Article
Full-text available
ABSTRACT Background: Post-traumatic stress disorder (PTSD) is an understudied construct in the psychiatric setting. The majority of existing Indian studies on PTSD focus on the general population or disaster-stricken communities. Here, we present data from a five-year retrospective chart review from a tertiary care psychiatric center in India. M...
Article
Full-text available
Purpose: The health-related quality of life (HRQoL) is an important endpoint in modern clinical practice with improved survival of pediatric posterior fossa malignant brain tumors (PFMBTs). We evaluated the effect of environmental and psychosocial milieu on QoL and cognitive functioning (CF) of Indian children with PFMBT. Methods: In a cross-sec...
Article
Full-text available
Objective: Voice tremor (VT) is one of the characteristics of essential tremor (ET). This study was designed to describe the group and phonatory characteristics of classic ET patients with VT. Methods: This retrospective case-control study compared classic ET patients with age and sex-matched controls. The ET population was subgrouped based on a...
Article
Full-text available
Background: Awake craniotomy encompasses surgical resection of focal zone of neurological impairment, using intraoperative functional zone mapping. The strength of the procedure is maximum retention of functionally significant zones to ensure better function and quality of life outcomes in patients. A clinical neuropsychologist plays a vital role...
Poster
Full-text available
This study aimed at evaluating relationship between neuro-cognition, music-cognition and emotion perception in mild-moderate Major depressive disorder. Patients and matched healthy controls were assessed on neuropsychological tests, music cognition and music emotion perception. Significant relationship between these variables was observed on correl...
Chapter
Full-text available
Global collaborative networks have been established in multiple fields to move beyond research that over-relies on "WEIRD" participants and to consider central questions from cross-cultural and epistemological perspectives. As researchers in music and the social sciences with experience building and sustaining such networks, we participated in a vi...
Article
Full-text available
Abstract: BACKGROUND AND PURPOSE: The corpus callosum (CC) consists of topographically arranged white matter (WM) fibers. Previous studies have indicated the CC to be discretely involved in WD. In this study, we strived to characterize the macrostructural properties of the CC using midsagittal cross-sectional area and thickness profile measureme...
Article
Full-text available
Background: Parkinson’s disease (PD) is characterized by bradykinesia, tremor, rigidity, postural instability and cognitive deficits in attention, executive functions, learning and memory. Motor speed, measured using Finger Tapping Test (FTT), is an important indicator and predictor of cognitive and motor functions. Deficits in motor speed have sig...
Preprint
Cognitive impairment is a debilitating non-motor symptom of Parkinson’s disease (PD). The diagnosis of PD with cognitive impairment (PDCI) is essentially through clinical and neuropsychological examinations. There is an emerging need to identify biomarker(s) to foresee cognitive decline in PD patients, at an early stage. We performed label-free unb...
Article
Objectives We aimed to (i) analyse the clinical characteristics, treatment outcome and long-term prognosis of anti-NMDAR encephalitis and (ii) study the differences between paediatric and adult patients.Methods This was a chart review of all patients with anti-NMDAR encephalitis.ResultsThere were 28 patients with 18 patients belonging to the paedia...
Article
Introduction Cognitive impairment is reported but is poorly explored in spinocerebellar ataxia 2 (SCA2). This study was undertaken to evaluate and classify cognitive impairment (CI) in patients with SCA2 and to identify their grey matter (GM) correlates. Methods We evaluated the neurocognitive profile of 35 SCA2 and 30 age-, gender- and education-...
Article
Background: Following mild-moderate traumatic brain injury (TBI), an individual experiences a range of emotional changes. It is often difficult for the patient to reconcile with their post-injury persona, and the memory of pre-injury personhood is particularly painful. Insight into one's cognitive deficits subsequent to injury can lead to an exist...
Article
Full-text available
Background: A specific learning disability comes with a cluster of deficits in the neurocognitive domain. Phonological processing deficits have been the core of different types of specific learning disabilities. In addition to difficulties in phonological processing and cognitive deficits, children with specific learning disability (SLD) are known...
Article
Full-text available
Background: The plastic nature of the human brain lends itself to experience and training-based structural changes leading to functional recovery. Music, with its multimodal activation of the brain, serves as a useful model for neurorehabilitation through neuroplastic changes in dysfunctional or impaired networks. Neurologic Music Therapy (NMT) co...
Article
Objective: White matter (WM) integrity of Spinocerebellar ataxia 2 (SCA2) is poorly understood, more so in the early stages of SCA2. In this study, we evaluated the microstructural integrity of the WM tracts with an emphasis on the nature of in‐vivo pathological involvement in early SCA2. Materials and methods: We evaluated the MRI images of 26 ge...
Article
Objective The objective of the current study was to compare the microstructural integrity of the white matter (WM) tracts in patients having Parkinson disease (PD) with and without psychosis (PD-P and PD-NP) through diffusion tensor imaging (DTI). Methods This cross-sectional study involved 48 PD-NP and 42 PD-P who were matched for age, sex, and e...
Article
Reduced amplitude and increased latency of P300 auditory event-related potential (ERP) in patients with schizophrenia (SZ) indicate impairment in attention. Overall arousal level can determine the amount of processing capacity required for attention allocation. Music evokes strong emotions and regulates arousability. Music has been used to modulate...
Conference Paper
Objective: i. To identify CSF protein biomarker/s in Parkinson’s disease (PD) with cognitive impairment using LC-MS/MS proteomics. ii. To estimate the level of known AD biomarkers in CSF of PD with cognitive impairment using Enzyme Linked Immunosorbent Assay (ELISA) Background: Cognitive impairment is a major non-motor symptom of PD. The cognitive...
Article
Full-text available
Music is one of the major activities that alters the emotional experience of a person. Musical processing in the brain is a complex process involving coordination between various areas of the brain. There are less number of studies that focus on analyzing brain responses due to music using modern signal processing techniques. This research aims to...
Conference Paper
Objective: Psychosis is one of the debilitating non-motor symptom of Parkinson’s disease (PD) which commonly manifests through minor hallucinations (such as passage hallucinations, presence hallucinations, and illusions) and well-formed visual hallucinations. Cognitive impairment is strongly associated with psychosis in PD (PD-P). This study aimed...
Article
Full-text available
Introduction: Dementia is a leading cause of morbidity in view of increasing expectation of life all over the world. With reference to Pharmacotherapy as well as non-pharmacological treatment options to be effective, diagnosis and therapy should be initiated very early. Currently, Diagnosis is made on clinical grounds and there is gross time delay....
Article
Cognitive deficits in individuals diagnosed with schizophrenia are ubiquitous and, therefore, cognitive remediation is considered one of the prime targets of a comprehensive intervention program for schizophrenia. However, cognitive remediation is a resource consuming intervention and in lower and middle-income countries (LAMIC) such interventions...
Conference Paper
Full-text available
Music is one of the major activities that alters the emotional experience of a person. Musical processing in the brain is a complex process involving coordination between various areas of the brain. There are less number of studies that focus on analyzing brain responses due to music using modern signal processing techniques. This research aims to...
Article
Full-text available
Psychosis, manifested through formed visual hallucinations or minor hallucinations, is a common non-motor symptom of Parkinson’s disease (PD). The pathogenesis of psychosis in PD remains unclear; however, is possibly linked to structural and functional alterations in the hippocampus. To explore the role of hippocampus in psychosis, a detailed hippo...
Conference Paper
Full-text available
Music is one of the major activities that alters the emotional experience of a person. Musical processing in the brain is a complex process involving coordination between various areas of the brain. There are less number of studies that focus on analyzing brain responses due to music using modern signal processing techniques. This research aims to...
Article
Introduction Patients with Parkinson’s disease (PD) may develop several non-motor symptoms (NMS). Psychosis is one of the debilitating NMS of PD. The neurobiology of psychosis is not fully understood. This study aims to compare the frontal lobe functions of PD patients with and without psychosis using the Frontal Assessment Battery (FAB). Methodol...
Article
Introduction: Psychosis is one of the common non-motor symptoms of PD, which substantially worsens the quality of life. Hence, it is important to identify factors that are associated with early onset of psychosis in PD. In order to identify those factors, the current study aims to compare various demographic and clinical features of PD patients wit...
Article
Full-text available
Cognitive deficits are reported in diabetes mellitus type 2 (DM2). Previous research has shown that music-based intervention can not only reduce hyperglycemia but also target cognitive functions as well as stress. The aim of this exploratory study was to understand the effect of active participation in music therapy (MT) on the cognitive deficits o...
Article
Full-text available
Music is a universal human trait. The healing power of music has been acknowledged in almost all traditions of music. Music therapy is moving from a social-science model focusing on overall health and well-being towards a neuroscience model focusing on specific elements of music and its effect on sensorimotor, language and cognitive functions. The...
Article
Cognitive deficits play a central role in recovery from Schizophrenia (SZ). Cognitive remediation (CR) is increasingly being examined to improve cognitive functions in SZ. It is becoming an inevitable component of treatment for this debilitating illness. This review article presents the current status of research on CR for SZ in India. In contrast...
Article
Abstract Background Patients with Parkinson’s disease (PD) have motor dysfunction, cognitive dysfunction, impairment in temporal processing and rhythm discrimination. Apart from beat-based rhythm discrimination, perception of other temporal components of rhythm such as meter, contour and beat perception in musical context has not been studied hith...
Article
Full-text available
Traumatic brain injury (TBI) is one of the common causes of disability in physical, psychological, and social domains of functioning leading to poor quality of life. TBI leads to impairment in sensory, motor, language, and emotional processing, and also in cognitive functions such as attention, information processing, executive functions, and memor...
Article
The aim was to examine the cognitive deficits profile in first episode schizophrenia patients as well as examine the correlation between cognitive deficits, psychopathology and global functioning. Better understanding of these various facets of this debilitating illness is imperative in planning treatment, thereby limiting decline in global functio...
Conference Paper
Full-text available
In Indian classical music (ICM) ‘ragas’ are the base for melodic improvisation. Ragas are closely associated with specific emotional themes, termed as ‘rasas’. Artists improvise and elaborate on a raga over different successive phases with variation in the melodic elaboration, tempo and rhythm to evoke the rasa of the raga. There has been little st...
Article
Music is a powerful elicitor of emotions. Emotions evoked by music, through autonomic correlates have been shown to cause significant modulation of parameters like heart rate and blood pressure. Consequently, Heart Rate Variability (HRV) analysis can be a powerful tool to explore evidence based therapeutic functions of music and conduct empirical s...
Article
Full-text available
We examined the effectiveness of a 2-month-long home-based cognitive retraining program together with treatment as usual (TAU; psychoeducation and drug therapy) on neuropsychological functions, psychopathology, and global functioning in patients with first episode schizophrenia (FES) as well as on psychological health and perception of level of fam...
Article
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Article
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Background: Systematic studies on neuropsychological profile in patients with Wilson′s disease (WD) are far and few. Aim: To examine the profile of cognitive deficits and their magnetic resonance imaging (MRI) findings in patients with WD. Patients and Methods: Twelve confirmed patients of WD (age at onset and evaluation, 13.7±11.2 and 21.7±5.3 yea...
Article
Full-text available
Systematic studies on neuropsychological profile in patients with Wilson's disease (WD) are far and few. To examine the profile of cognitive deficits and their magnetic resonance imaging (MRI) findings in patients with WD. Twelve confirmed patients of WD (age at onset and evaluation, 13.7±11.2 and 21.7±5.3 years, respectively; M-F ratio, 7:5) on de...
Article
Objective. Studies have demonstrated the independent effectiveness of cognitive retraining and family interventions in schizophrenia. The improvements in cognitive functions following the retraining are poorly sustained, which could be due to the absence of a supportive and congenial family environment to sustain the gains of the retraining program...

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Projects

Projects (4)
Project
Brain Imaging techniques and Brain Computer Interface training as new therapy approach in the field of language disorders. The BCI training in collaboration with the BCI Lab, B.R.A.I.N. Center, Department of Life Sciences, University of Trieste.