Shalini SanyalInstitute for Stem Cell Science and Regenerative Medicine · Laboratory of Self Assembled Bio-materials
Shalini Sanyal
Ph.D.
SERB National Post Doctoral Fellow, inStem
About
19
Publications
3,131
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63
Citations
Citations since 2017
Introduction
Currently working at Laboratory of Self Assembled Bio-materials, DBT-inStem. Recipient of Young Scientist Award’19 for my doctoral research, completed under the aegis of DST-INSPIRE Fellowship.
Contributed to the effort to battle the pandemic by working at NCBS-inStem COVID19 Facility & by translating scientific jargon into regional language as part of CovidGyan team.
Cell biologist by profession with background in murine behavior, cell culture,cellular assays, microscopy & flowcytometry.
Additional affiliations
March 2021 - March 2021
DBT-Institute for Stem Cell Science and Regenerative Medicine
Position
- PostDoc Position
Description
- Investigating ways to mitigate pesticide induced ocular insult.
August 2020 - February 2021
National Centre for Biological Sciences- Institute for Stem Cell Science and Regenerative Medicine
Position
- Scientific Staff
Description
- Frontline worker in the battle against the Coronavirus-2.
November 2019 - June 2020
Institute for Stem Cell Science and Regenerative Medicine
Position
- PostDoc Position
Education
September 2010 - September 2012
Publications
Publications (19)
The conversion of physiology to pathophysiology in hematological disorders viz: aplastic anemia, myelodysplastic syndrome (MDS) and leukemia in murine models was the subject of study in the present programme. Peripheral blood hemogram, spleno-somatic index, bone marrow smear study, cytochemical staining of marrow, cell release kinetics study during...
Pesticide exposure can occur directly or indirectly in an occupational setting or otherwise. The health hazards of pesticides have long been studied; however, little is known about the ocular insult of these potent chemicals. In this study, we examined the consequences of long-term pesticide exposure on the ocular tissue in animal model with specia...
Ocular toxicity as a consequence of chronic pesticide exposure is one of the health hazards caused due to extended exposure to pesticides. The cornea, due to its position as the outer ocular layer and its role in protecting the internal layers of the eye; is gravely affected by this xenobiotic insult to the eye, leading to ocular irritation and dam...
The consequences of chronic pesticide exposure on the ocular surface are not yet fully known and lacunae exist regarding the repercussions of this xenobiotic insult on cellular turnover. The present work aims to establish the mechanistic relationship between ocular morbidity and chronic pesticide exposure by analyzing the impact on key regulators r...
Pesticides aid in crop-protection against pests and increase yield. However, the xenobiotic stress exerted by pesticides leads to the deterioration of human and animal health. There is a lacuna in our knowledge about their impact on the ocular surface The present work sheds light on this gap by analysing the deterioration of visual acuity as a cons...
Wound healing is a complex, multiple-step mechanism and most lead to the development of scars, which may or may not affect the functional capability of the healed tissue. However, with the advanced healing techniques and our improved understanding of the wound-healing process, there has been some development towards limiting the scarification that...
The ocular surface, which is constantly exposed to the external environment, is one of the most sensitive zones and any complications which have a detrimental impact on it leading to reduced vision and/or blindness, severely impact the quality of life. The most commonly afflicted parts of the eye are the conjunctiva, eyelid, and cornea due to their...
Pesticides are extensively used to promote crop-development. However, this protection from loss of harvest is at the cost of various health defects such as neuropathies, haematological disorders, dermal problems and numerous issues associated with ocular discomfort due to the non-target effect of pesticides. Pesticide exposure can occur in both occ...
Hemoglobin is the major carrier of respiratory gases to the different tissues of the body. ...This chapter aims to provide a detailed introduction to hemoglobin and its characteristic features. The chapter discusses the different forms of globin genes, the structural and functional features of HbF and the detection methods for HbF. ...
Relevance:
Malignant peritoneal sarcomatosis related ascitic formation often leads to grave consequences but the therapeutic management of the fatal pathophysiological condition remains a rarely discussed issue. The present study investigates the anti-neoplastic activity of the plant alkaloid from Ruta graveolens on ascitic Sarcoma-180 bearing mic...
Questions
Questions (10)
I am looking to apply for post-doctoral positions in ocular research.
BRIEF BACKGROUND: My doctoral work was establishing pesticide-induced ocular damage using a murine model and my current (PD) work is on determining whether intervention through topical herbal instillations can mitigate the pesticide induced ocular damage.
I would like to apply for the MSCA Global Fellowship and am looking for a host.
Any leads would be appreciated.
Thanks in advance!
I received an invitation to author a book chapter in an open access book from a relatively well-known publishing house recently. When accepting the invite, I had mentioned my lack (complete absence, to be honest) of funding to pay OAPF and was assured of waivers. However, now that my chapter has been submitted- AND accepted, they are providing a 70% waiver, citing inability to provide full waiver. Post discount the amount is ~400GBP, which converted to my native currency is higher than my monthly fellowship. Are such high OAPF’s the norm? Especially for invited chapters?
And are there any sponsorships available to help me in paying this amount?
My only other alternative is withdrawing the chapter.
Please advise!
I have obtained a herbal extract obtained by directly crushing the tissue (no solvent used). If I store said extract at 4’C; some constituents appear to settle down at the bottom of the storage tube which dissolve immediately upon lightly shaking the tube. Moreover, the scent of the extract is also comparatively milder upon storage. Literature reviews have indicated that the extract is composed of several volatile components which undergo spontaneous conversion.
It would be much appreciated if methods for comparing fresh extract and the stored extract for any change in composition (apart from HPLC) can be recommended?
(Ps.- I do not have extensive background in chemistry, in case that is something that you need to know to make recommendations).
Projects
Project (1)
Mitigating ocular issues caused due to environmental exposure (specifically pesticides) by therapeutic intervention
