Shah Krupa

Shah Krupa
Manipal Academy of Higher Education | MAHE · Department of Obstetrics and Gynaecology

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25
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Publications

Publications (25)
Article
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Objective: First trimester aneuploidy screening (FTAS) has become an integral part of antenatal care in most of centers in India. The serum markers used for FTAS are pregnancy-associated plasma protein A (PAPP-A) and beta human chorionic gonadotropin. In the present study, we aimed to assess the role of PAPP-A in specific adverse fetal maternal ev...
Article
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Recurrent Pregnancy Loss (RPL) is an important reproductive issue, affecting 1-5% of couples. It is characterised by repeated miscarriage, impairing the ability to have a live birth. The proven causes are diverse, such as cytogenetic abnormality, uterine anomalies, antiphospholipid antibody, metabolic and endocrine abnormalities, and about 50% case...
Article
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Introduction: Routinely performed aneuploidy screen takes into account free beta human chorionic gonadotrophins (β-hCG), Pregnancy Associated Plasma Protein-A (PAPP-A), nuchal translucency, and various maternal characteristics. Incidental finding of extreme level of PAPP-A can generate anxiety. Association of low PAPP-A has been established with ch...
Article
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Nephrotic Syndrome (NS), a unique renal disease complex associated with heavy proteinuria (protein excretion >3.5 gm/day), hypoalbuminemia (<30 gm/L) and peripheral oedema is a rare entity in pregnancy with an incidence of about 0.012-0.025%. There have been very few reports of pregnancy with co-existing NS. We hereby report a case of steroid sensi...
Article
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Introduction: A female encounters various menstrual disorders from puberty to menopause. We evaluated menstrual disturbances in post-menarche age and young adult age. Aim: To know the prevalence and impact of menstrual abnormalities at early adolescent and young adult age and to evaluate course of disorders identified at early adolescent age. Mater...
Article
Congenital pulmonary airway malformation (CPAM) is a rare developmental lung abnormality. It is also referred as a congenital cystic adenomatoid malformation. The exact etiology is not known yet. The majority of cases are detected during targeted prenatal scan or within 2 years of the birth. Here, we report a case of CPAM type II diagnosed at 23 we...
Article
Case: We report a unique combination of neonatal bilateral proximal femoral focal deficiency with a congenital tibiofemoral fusion of the right leg. Conclusion: To the best of our knowledge, the combination of proximal femoral focal deficiency and the congenital absence of the knee joint in a child has not previously been reported.
Article
Tibial hemimelia is a rare congenital limb deficiency which is characterised by a hypoplastic/aplastic tibia. It actually represents a spectrum of anomalies, ranging from mild hypoplasia of the tibia to total absence of the tibia. Several classifications based on radiological description exist in the literature. The tibial hemimelia is usually desc...
Article
Urorectal septum malformation sequence (URSMS) is a rare, spectrum of malformations, involving various organ systems. Here, we present eight cases of URSMS, noted in autopsy, with different degrees of complexity, seven being the complete type and one being the partial type. All cases had gastrointestinal tract malformation in the form of the imperf...
Article
Amniotic constriction bands and osteogenesis imperfecta are disorders arising from a collagen defect. We report a rare association of amniotic bands with osteogenesis imperfecta in a child. The child was born with multiple amniotic bands involving the right leg, both hands and both feet. Multiple fractures of long bones of lower limbs occurred in c...
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Hypoparathyroidism is an uncommon endocrine deficiency characterised by low serum calcium, absent or inappropriately low parathyroid hormone and normal or high serum phosphorus levels. Parathyroid hormone is essential for calcium homoeostasis. Pregnancy and lactation are known for increased calcium requirement. They cause calcium stress as well as...
Article
Werner mesomelia is characterized by a sequence variation in the specific region (position 404) of the enhancer ZRS of SHH. The phenotype comprises variable mesomelia, abnormalities of the thumb and great toe and supernumerary digits. We describe extensive variation in limb phenotype in a large family and report on a novel sequence variation NG_009...
Article
Full-text available
Premature rupture of membrane is managed either expectantly or actively. The purpose of the study was to assess the effectiveness of early labor induction with cervical prostaglandin E2 versus expectant management in women with term premature rupture of membrane. Singleton pregnancy cases with cephalic presentation reported between 37 and 41 weeks...

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