Seyi Soremekun

Seyi Soremekun
London School of Hygiene and Tropical Medicine | LSHTM · Department of Population Health

PhD

About

48
Publications
9,532
Reads
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1,370
Citations
Citations since 2017
22 Research Items
1059 Citations
2017201820192020202120222023050100150200
2017201820192020202120222023050100150200
2017201820192020202120222023050100150200
2017201820192020202120222023050100150200
Additional affiliations
October 2004 - August 2008
University of Warwick
Position
  • PhD Student
October 2003 - September 2004
Imperial College London
Position
  • Research Associate

Publications

Publications (48)
Article
Background: Early adversities negatively impact children’s growth and development, putatively mediated by chronic physiological stress resulting from these adverse experiences. We aimed to estimate the associations between prospectively measured cumulative early adversities with growth and cognition outcomes in rural Indian preschool children and t...
Article
Full-text available
Background Globally, nearly half of all deaths among children under the age of 5 years can be attributed to malaria, diarrhoea, and pneumonia. A significant proportion of these deaths occur in sub-Saharan Africa. Despite several programmes implemented in sub-Saharan Africa, the burden of these illnesses remains persistently high. To mobilise resour...
Preprint
Background The majority of post-neonatal deaths in children under 5 are due to malaria, diarrhoea and pneumonia (MDP). The WHO recommends integrated community case management (iCCM) of these conditions using community-based health workers. However iCCM programmes have suffered from poor implementation and mixed outcomes. We designed and evaluated a...
Article
Background: Early adversities negatively impact children’s growth and development, putatively mediated by chronic physiological stress resulting from these adverse experiences. We aimed to estimate the associations between prospectively measured cumulative early adversities with growth and cognition outcomes in rural Indian preschool children and t...
Article
Background: The World Health Organization and others promote responsive caregiving to support all children to thrive, particularly in low- and middle-income countries. The 14-item Mother’s Object Relations Scales – Short Form (MORS-SF) may be of use in research and public health programmes because of its basis in attachment theory and ability to ca...
Article
Full-text available
Background Globally adopted health and development milestones have not only encouraged improvements in the health and wellbeing of women and infants worldwide, but also a better understanding of the epidemiology of key outcomes and the development of effective interventions in these vulnerable groups. Monitoring of maternal and child health outcome...
Article
Full-text available
Background Successful implementation of community-based research is dominantly influenced by participation and engagement from the local community without which community members will not want to participate in research and important knowledge and potential health benefits will be missed. Therefore, maximising community participation and engagement...
Conference Paper
Full-text available
Background The period through pregnancy and the early years is crucial for optimising child growth, development and lifelong well-being. Son-preference (family desire for male over female children) disadvantages girls through mechanisms including unequal distribution of resources (e.g. food or medicine) and parental-time, abuse, short birth interva...
Article
Full-text available
Objective: To evaluate the associations of depressive symptoms and antidepressant use during pregnancy with the risks of preterm birth, low birth weight, small for gestational age (SGA), and low Apgar scores. Data sources: MEDLINE, EMBASE, ClinicalTrials.gov, and PsycINFO up to June 2016. Methods of study selection: Data were sought from studi...
Article
Full-text available
Background There is an urgent need to fill the gap of scalable cognitive assessment tools for preschool children to enable identification of children at-risk of sub-optimal development and to support their timely referral into interventions. We present the associations between growth in early childhood, a well-established marker of cognitive develo...
Article
Full-text available
Background Maternal morbidity occurs several times more frequently than mortality, yet data on morbidity burden and its effect on maternal, foetal, and newborn outcomes are limited in low- and middle-income countries. We aimed to generate prospective, reliable population-based data on the burden of major direct maternal morbidities in the antenatal...
Article
Background: The World Health Organization and others promote responsive caregiving to support all children to thrive, particularly in low- and middle-income countries. The 14-item Mother’s Object Relations Scales – Short Form (MORS-SF) may be of use in research and public health programmes because of its basis in attachment theory and ability to ca...
Article
Child sexual abuse (CSA) is a global health problem with significant health consequences. The World Health Organization recommends immediate and long-term treatment for all survivors. However, in low- and middle-income countries, less than 10 % of sexually abused children seek health services. Community health workers (CHWs) can potentially increas...
Article
Full-text available
Background: Maternal and perinatal mortality are still unacceptably high in many countries despite steep increases in facility birth. The evidence that childbirth in facilities reduces mortality is weak, mainly because of the scarcity of robust study designs and data. We aimed to assess this link by quantifying the influence of major determinants...
Article
Full-text available
Background: The majority of the world's children live in low- and middle-income countries and face multiple obstacles to optimal wellbeing. The mechanisms by which adversities - social, cultural, psychological, environmental, economic - get 'under the skin' in the early days of life and become biologically embedded remain an important line of enqu...
Conference Paper
Full-text available
Background and aims Improving early childhood development globally will lead to improved health and wellbeing for all and is key to achieving the ambitious Sustainable Development Goals. Exposure to a cumulative burden of adversity is detrimental to child health and wellbeing across the lifecourse, but the relative importance of the very early year...
Article
Full-text available
Introduction Early childhood development is key to achieving the Sustainable Development Goals and can be negatively influenced by many different adversities including violence in the home, neglect, abuse and parental ill-health. We set out to quantify the extent to which multiple adversities are associated with impaired early childhood growth & de...
Article
Full-text available
Background: A key barrier to appropriate treatment for malaria, diarrhoea, and pneumonia (MDP) in children under 5 years of age in low income rural settings is the lack of access to quality health care. The WHO and UNICEF have therefore called for the scale-up of integrated community case management (iCCM) using community health workers (CHWs). Th...
Article
Full-text available
Background: Modelled mortality estimates have been useful for health programmes in low-income and middle-income countries. However, these estimates are often based on sparse and low-quality data. We aimed to generate high quality data about the burden, timing, and causes of maternal deaths, stillbirths, and neonatal deaths in south Asia and sub-Sa...
Article
Full-text available
Background: In Kenya, most sexual violence survivors either do not access healthcare, access healthcare late or do not complete treatment. To design interventions that ensure optimal healthcare for survivors, it is important to understand the characteristics of those who do and do not access healthcare. In this paper, we aim to: compare the charac...
Article
Full-text available
Background: Antibody responses to sand fly saliva have been suggested to be a useful marker of exposure to sand fly bites and Leishmania infection and a potential tool to monitor the effectiveness of entomological interventions. Exposure to sand fly bites before infection has also been suggested to modulate the severity of the infection. Here, we...
Article
Full-text available
Objective To estimate neonatal mortality, particularly within 24 hours of birth, in six low- and lower-middle-income countries. Methods We analysed epidemiological data on a total of 149 570 live births collected between 2007 and 2013 in six prospective randomized trials and a cohort study from predominantly rural areas of Bangladesh, Ghana, India...
Article
Full-text available
Objectives The AMANHI mortality study aims to use harmonized methods, across eleven sites in eight countries in South Asia and sub–Saharan Africa, to estimate the burden, timing and causes of maternal, fetal and neonatal deaths. It will generate data to help advance the science of cause of death (COD) assignment in developing country settings. Me...
Article
Full-text available
Facility delivery is an important aspect of the strategy to reduce maternal and newborn mortality. Geographic access to care is a strong determinant of facility delivery, but few studies have simultaneously considered the influence of facility quality, with inconsistent findings. In rural Brong Ahafo region in Ghana, we combined surveillance data o...
Article
Full-text available
Objectives To evaluate the impact of Newhints community-based surveillance volunteer (CBSV) assessments and referrals on access to care for sick newborns and on existing inequities in access. Design We evaluated a prospective cohort nested within the Newhints cluster-randomised controlled trial. Setting Community-based intervention involving more t...
Article
Full-text available
Background: Every year, 2·9 million newborn babies die worldwide. A meta-analysis of four cluster-randomised controlled trials estimated that home visits by trained community members in programme settings in Ghana and south Asia reduced neonatal mortality by 12% (95% CI 5–18). We aimed to estimate the costs and cost-effectiveness of newborn home vi...
Article
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We report a cluster-randomised trial of a home-based counselling strategy, designed for large-scale implementation, in a population of 1.2 million people in rural southern Tanzania. We hypothesised that the strategy would improve neonatal survival by around 15%. In 2010 we trained 824 female volunteers to make three home visits to women and their...
Article
Full-text available
Objectives To assess the impact of probable depression in the immediate postnatal period on subsequent infant mortality and morbidity. Design Cohort study nested within 4 weekly surveillance of all women of reproductive age to identify pregnancies and collect data on births and deaths. Setting Rural/periurban communities within the Kintampo Health...
Article
Full-text available
If trained, equipped and utilised, community health workers (CHWs) delivering integrated community case management for sick children can potentially reduce child deaths by 60%. However, it is essential to maintain CHW motivation and performance. The inSCALE project aims to evaluate, using a cluster randomised controlled trial, the effect of interve...
Article
Full-text available
Background The burden of malaria remains high for children in parts of Africa despite the use of insecticide-treated bed nets (ITNs). Chemoprevention has the potential of reducing the malaria burden; however, limited data exist on the efficacy and safety of anti-malarial therapy in the setting of chemoprevention.Methods600 children 4¿5 months of ag...
Article
Risk factors for postnatal depression (PND), one of the most pervasive complications of child bearing, are poorly understood in Africa. A recent systematic review of 31 studies found that the strongest predictors are social and economic disadvantage and gender-based factors; only six of these studies were community based, and almost all were in Sou...
Article
Full-text available
Whilst there is compelling evidence of an almost 2-fold increased risk of still births, and suggestive evidence of increased mortality among offspring of mothers with psychotic disorders, only three studies have addressed the role of antenatal depression (AND) on survival of the baby. We examined these associations in a large cohort of pregnant wom...
Article
Full-text available
A World Health Organization (WHO)/United Nations Children's Fund (UNICEF) (2009) joint statement recommended home visits by community-based agents as a strategy to improve newborn survival, based on promising results from Asia. This article presents detailed evaluation of community volunteer assessment and referral implemented within the Ghana Newh...
Article
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Background Access to skilled attendance at childbirth is crucial to reduce maternal and newborn mortality. Several different measures of geographic access are used concurrently in public health research, with the assumption that sophisticated methods are generally better. Most of the evidence for this assumption comes from methodological comparison...
Article
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Objectives To assess the extent of socio-economic inequity in coverage and timeliness of key childhood immunisations in Ghana.Methods Secondary analysis of vaccination card data collected from babies born between January 2008 and January 2010 who were registered in the surveillance system supporting the ObaapaVita and Newhints Trials was carried ou...
Article
Objective To evaluate whether the Newhints home visits intervention increased the adoption of skin-to-skin care (SSC), in particular, among low birthweight (LBW) (<2.5kg) babies. MethodsA cluster-randomised trial, with 49 Newhints zones and 49 control zones, was conducted in seven districts in the Brong Ahafo Region, Ghana. It included all live bir...
Article
Background: In 2009, on the basis of promising evidence from trials in south Asia, WHO and UNICEF issued a joint statement about home visits as a strategy to improve newborn survival. In the Newhints trial, we aimed to test this home-visits strategy in sub-Saharan Africa by assessing the effect on all-cause neonatal mortality rate (NMR) and essent...
Article
Full-text available
This paper presents a method employed in building a semantically annotated corpus of 11,741 Verbal Autopsy documents, each annotated with Cause of Death, based on verbal records of deaths of mothers, stillbirths, and infants up to 1 year of age, captured for analysis in Ghana between December 2000 and July 2010. Verbal Autopsy is a technique which...
Article
Full-text available
An annotated corpus is essential to the development and evaluation of automatic approaches in corpus linguistics research. The biomedical domain is one area that is witnessing a high growth of corpus based approaches to the development of automatic systems. This paper presents a method employed in building a semantically annotated corpus of 11,741...
Article
Full-text available
Background Many sub-Saharan countries, including Ghana, have introduced policies to provide free medical care to pregnant women. The impact of these policies, particularly on access to health services among the poor, has not been evaluated using rigorous methods, and so the empirical basis for defending these policies is weak. In Ghana, a recent re...
Article
Background: Many sub-Saharan countries, including Ghana, have introduced policies to provide free medical care to pregnant women. The impact of these policies, particularly on access to health services among the poor, has not been evaluated using rigorous methods, and so the empirical basis for defending these policies is weak. In Ghana, a recent r...
Article
Full-text available
Background Tackling neonatal mortality is essential for the achievement of the child survival millennium development goal. There are just under 4 million neonatal deaths, accounting for 38% of the 10.8 million deaths among children younger than 5 years of age taking place each year; 99% of these occur in low- and middle-income countries where a lar...
Article
Summary Insecticide-treated nets have proved successful in the prevention of malaria as a result of both the personal protection with which they provide the sleeper and also the 'mass effect' on the local mosquito population when they are used on a community-wide basis. Personal protection estimates are normally based on comparisons of the numbers...
Article
Full-text available
Unregistered deaths account for over 67 percent of global annual deaths. These deaths occur in poor resource countries where no or weak death registration system exists. Verbal Autopsy is a technique recommended by the World Health Organization (WHO) to determine the causes of deaths in countries with poor death registration systems. Traditional ap...

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Projects

Projects (3)
Archived project
The Innovations at Scale for Community Access and Lasting Effects (inSCALE) project aimed to demonstrate that government-led iCCM programmes could be scaled up while maintaining quality of care by addressing the common barriers to iCCM implementation emphasised in the literature.
Project
This project will determine population-based burden, timing, and causes of maternal deaths, stillbirths and neonatal deaths in Bangladesh; identify the burden of severe acute maternal morbidity (SAMM) in the study populations and document the care received for each of the morbidities; and determine the association of maternal morbidity with stillbirth, preterm birth, intrauterine growth restriction and neonatal mortality. It is also aimed to establish a bio-repository for testing the bio marker of adverse maternal and perinatal outcome.